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    • 5. 发明申请
    • Automatic Multi-Level Therapy Based on Morphologic Organization of an Arrhythmia
    • 基于心律失常的形态学组织的自动多层次治疗
    • US20110166613A1
    • 2011-07-07
    • US13048582
    • 2011-03-15
    • Dan LiYayun Lin
    • Dan LiYayun Lin
    • A61N1/365A61N1/39
    • A61N1/3622A61B5/04525A61B5/0464A61N1/36585A61N1/3962
    • Methods and systems for selecting tachyarrhythmia therapy based on the morphological organization level of the arrhythmia are described. Morphological organization levels of arrhythmias are associated with cardiac therapies. The morphological organization levels are related to cardiac signal morphologies of the arrhythmias. An arrhythmia episode is detected and the morphological organization level of the arrhythmia episode is determined. A cardiac therapy associated with the morphological organization level of the arrhythmia episode is delivered to treat the arrhythmia. For example, the morphological organization levels may be associated with the cardiac therapies based on one or more of retrospective database analysis, patient therapy tolerance, and physician input. The associations may be static or may be dynamically adjusted based on therapy efficacy.
    • 描述了基于心律失常形态组织水平选择快速性心律失常治疗的方法和系统。 心律失常的形态学组织水平与心脏治疗有关。 形态组织水平与心律失常的心脏信号形态有关。 检测到心律失常发作,确定心律失常发作的形态组织水平。 与心律失常发作的形态组织水平相关的心脏治疗被递送以治疗心律失常。 例如,形态组织水平可以基于回顾性数据库分析,患者治疗耐受性和医师输入中的一种或多种与心脏疗法相关联。 协会可以是静态的,或者可以基于治疗功效来动态调整。
    • 6. 发明授权
    • Cardiac template generation based on patient response information
    • 基于患者应答信息的心脏模板生成
    • US07933651B2
    • 2011-04-26
    • US10995704
    • 2004-11-23
    • Shelley Marie CazaresYayun LinAlok S. Sathaye
    • Shelley Marie CazaresYayun LinAlok S. Sathaye
    • A61B5/0452
    • A61B5/042A61N1/3702A61N1/3925
    • Cardiac treatment methods and devices provide for templates representative of past tachyarrhythmia events, each template associated with a therapy. Methods involve providing a cardiac waveform representative of a patient's cardiac activity and identifying a portion that indicates an arrhythmic event. A cardiac template corresponding to the portion is generated, and a therapy is associated with the template useful for treating a subsequent arrhythmia. The waveform portion may be identified by a physician using a patient-external device to display the cardiac waveform. The template may be generated by a physician selecting the cardiac waveform, and determining if the therapy associated with the template was satisfactory and/or effective in treating the arrhythmia. Identification may involve matching the event to templates generated using cardiac waveforms other than the patient's cardiac waveforms. The template may be generated in a patient-internal or patient-external medical device such as a programmer, and/or an advanced patient management system.
    • 心脏治疗方法和装置提供代表过去快速性心律失常事件的模板,每个模板与治疗相关联。 方法包括提供代表患者心脏活动的心脏波形并识别指示心律失常事件的部分。 产生对应于该部分的心脏模板,并且与可用于治疗随后的心律失常的模板相关联的治疗。 波形部分可以由医师使用患者外部设备来识别,以显示心脏波形。 模板可以由医师选择心脏波形产生,并且确定与模板相关联的治疗是否令人满意和/或有效地治疗心律失常。 识别可能涉及将事件与使用除患者心脏波形之外的心脏波形产生的模板进行匹配。 模板可以在诸如程序员和/或高级患者管理系统的患者内部或患者外部医疗设备中生成。
    • 7. 发明申请
    • Arrhythmia discrimination based on determination of rate dependency
    • 基于速率依赖性确定的心律失常辨别
    • US20070142737A1
    • 2007-06-21
    • US11312280
    • 2005-12-20
    • Shelley CazaresJaeho KimYayun LinCarlos Ricci
    • Shelley CazaresJaeho KimYayun LinCarlos Ricci
    • A61B5/04
    • A61B5/0464A61B5/04525A61B5/7264
    • Cardiac systems and methods provide for discriminating between supraventricular tachyarrhythmia and ventricular tachyarrhythmia based on a determination that the patient's supraventricular rhythm exhibits rate dependency. One approach involves determining if a patient's supraventricular rhythm exhibits rate dependent morphology. If the patient's supraventricular rhythm is determined to exhibit rate dependent morphology, an implantable device classifies a detected tachyarrhythmia episode based on one or more templates selected from a plurality of rate-indexed templates stored in the device. Determining if the supraventricular rhythm exhibits rate dependent morphology may also include determining one or more rates at which the rate dependent morphology occurs.
    • 心脏系统和方法基于确定患者的室上节律表现出速率依赖性,确定了室上性快速性心律失常与室性快速性心律失常之间的区别。 一种方法涉及确定患者的室上节律是否表现出速率依赖性形态。 如果确定患者的室上节律表现出与速率相关的形态,则可植入装置基于从存储在装置中的多个速率索引模板中选择的一个或多个模板来分类检测到的快速性心律失常发作。 确定室性心律显示出速率依赖性形态还可以包括确定发生速率依赖形态的一个或多个速率。