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    • 4. 发明授权
    • Fumaric acid derivatives and ophthalmic lenses using the same
    • 富马酸衍生物和使用其的眼科镜片
    • US08101701B2
    • 2012-01-24
    • US11766857
    • 2007-06-22
    • Takahito ItohTakahiro UnoMasato OhnishiYasuyuki KatoTakashi Otsu
    • Takahito ItohTakahiro UnoMasato OhnishiYasuyuki KatoTakashi Otsu
    • C08F26/06C08F230/08G02C7/02
    • C07F7/0838
    • Fumaric acid derivatives and ophthalmic lenses using them are disclosed. More specifically, a fumaric acid derivative having a hydrophilic group and a silicon-containing alkyl group within a molecule, and contact lenses or intraocular lenses using the same are disclosed. The fumaric acid derivatives of the present invention provide, on one hand, superior oxygen permeability by having a silicon-containing alkyl group within the molecular structure, and on the other hand, improved compatibility with other hydrophilic monomers by having a hydrophilic group within the same molecule. When ophthalmic lenses obtained by polymerizing monomer compositions containing the fumaric acid derivative are constructed as, for example, water content lenses, lenses with high oxygen permeability independent from the water content may be obtained, wherein the fumaric acid derivatives is superior in compatibility with the hydrophilic monomer used in combination and allows the combination in various mixing ratios.
    • 公开了富马酸衍生物和使用它们的眼科镜片。 更具体地,公开了在分子内具有亲水基团和含硅烷基的富马酸衍生物,以及使用其的隐形眼镜或人工晶状体。 本发明的富马酸衍生物一方面通过在分子结构内具有含硅烷基而提供优异的透氧性,另一方面通过在其内具有亲水性基团来提高与其它亲水性单体的相容性 分子。 当通过聚合含有富马酸衍生物的单体组合物获得的眼镜片被构造为例如含水透镜时,可以获得与透湿性无关的具有高氧渗透性的透镜,其中富马酸衍生物与亲水性相容性优异 单体组合使用并允许以各种混合比例组合。
    • 5. 发明申请
    • Fumaric Acid Derivatives and Ophthalmic Lenses Using the Same
    • 富马酸衍生物和使用其的眼科镜片
    • US20080132666A1
    • 2008-06-05
    • US11766857
    • 2007-06-22
    • Takahito ItohTakahiro UnoMasato OhnishiYasuyuki KatoTakashi Otsu
    • Takahito ItohTakahiro UnoMasato OhnishiYasuyuki KatoTakashi Otsu
    • C08F30/08C07F7/08C07F7/10C08G77/20C08F26/06
    • C07F7/0838
    • The present invention relates to fumaric acid derivatives and ophthalmic lenses using them. More specifically, the present invention relates to a fumaric acid derivative having a hydrophilic group and a silicon-containing alkyl group within a molecule, and to contact lenses or intraocular lenses.The fumaric acid derivatives of the present invention provide, on one hand, superior oxygen permeability by having a silicon-containing alkyl group within the molecular structure, and on the other hand, improved compatibility with other hydrophilic monomers by having a hydrophilic group within the same molecule. When ophthalmic lenses obtained by polymerizing monomer compositions containing the fumaric acid derivative are constructed as, for example, water content lenses, lenses with high oxygen permeability independent from the water content may be obtained, wherein the fumaric acid derivatives is superior in compatibility with the hydrophilic monomer used in combination and allows the combination in various mixing ratios.
    • 本发明涉及使用它们的富马酸衍生物和眼用透镜。 更具体地,本发明涉及分子内具有亲水基团和含硅烷基的富马酸衍生物,并且涉及隐形眼镜或人工晶状体。 本发明的富马酸衍生物一方面通过在分子结构内具有含硅烷基而提供优异的透氧性,另一方面通过在其内具有亲水性基团来提高与其它亲水性单体的相容性 分子。 当通过聚合含有富马酸衍生物的单体组合物获得的眼镜片被构造为例如含水透镜时,可以获得与透湿性无关的具有高氧渗透性的透镜,其中富马酸衍生物与亲水性相容性优异 单体组合使用并允许以各种混合比例组合。