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    • 8. 发明授权
    • DNA fragments containing gene having function relating to autonomous proliferation of plasmid
    • 含有与质粒自主增殖有关的功能基因的DNA片段
    • US07557202B2
    • 2009-07-07
    • US10482156
    • 2002-07-03
    • Wataru MizunashiFujio Yu
    • Wataru MizunashiFujio Yu
    • C07H21/04C12N1/20C12N15/00
    • C07K14/195C12N15/69
    • Provided are a DNA fragment containing a gene relating the autonomous replication of a plasmid, and a DNA fragment containing a gene relating to the autonomous replication of a plasmid wherein a mutation point capable of increasing the number of copies of a plasmid is present in at least one site in the gene. Also provided are a DNA fragment containing a gene having a function relating to the autonomous replication of a plasmid within the bacteria of the genus Rhodococcus, a DNA fragment wherein a mutation point capable of increasing the number of copies of a plasmid is present in at least one site in the gene, and a plasmid carrying a DNA fragment wherein a mutation point capable of increasing the number of copies of a plasmid is present in at least one site of the gene.
    • 提供了含有与质粒自主复制有关的基因的DNA片段和含有与质粒自主复制有关的基因的DNA片段,其中能够增加质粒拷贝数的突变点至少存在 基因中的一个位点。 还提供了含有与红球菌属细菌中的质粒自主复制有关的功能的基因的DNA片段,其中至少存在能增加质粒拷贝数的突变点的DNA片段 该基因的一个位点和携带DNA片段的质粒,其中能够增加质粒拷贝数的突变点存在于该基因的至少一个位点。