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1. 发明申请

US20110274673A1 Bacillus amyloliquefaciens Strain 有权
标题翻译：解淀粉芽孢杆菌菌株
公开(公告)号：US20110274673A1
公开(公告)日：2011-11-10
申请号：US13099717
申请日：2011-05-03
申请人： Yaowei Kang , Shawn Semones , Jessica Smith , Michael Frodyma
发明人： Yaowei Kang , Shawn Semones , Jessica Smith , Michael Frodyma
IPC分类号： A01N63/00 , C12N9/26 , C12N9/42 , C12N9/16 , A01P3/00 , C12N9/88 , C12N9/08 , C12N9/02 , C12N9/50 , C12N1/20 , C12N9/24
CPC分类号： C12R1/07 , A01N63/00 , A01N63/02 , C11D3/381 , C11D3/38609 , C11D3/38618 , C12N1/20 , Y10S435/832
摘要： The present disclosure relates to a strain of Bacillus amyloliquefaciens bacteria that hyperproduces amylase enzyme and protease enzyme. The strain is also suitable for producing lipase for the degradation of oleaginous materials such as fats, greases and cooking oils. The strain also has excellent fungicidal and/or fungistatic qualities. The strain of the present disclosure and the enzymes produced thereby have a number of applications, including agricultural uses, laundry and dish detergents, drain cleaners and spot removers, and among other things, baking applications.
摘要翻译：本公开涉及超生产淀粉酶和蛋白酶的解淀粉芽孢杆菌细菌菌株。该菌株也适用于生产用于脂肪，油脂和食用油等含油物质降解的脂肪酶。该菌株还具有优异的杀真菌和/或抑菌特性。本公开的菌株和由此产生的酶具有许多应用，包括农业用途，洗衣和洗涤剂，排水清洁剂和斑点去除剂，以及其它烘焙应用。

2. 发明授权

US08236549B2 Bacillus amylollquefaciens strain 有权
标题翻译：淀粉芽孢杆菌菌株
公开(公告)号：US08236549B2
公开(公告)日：2012-08-07
申请号：US13099717
申请日：2011-05-03
申请人： Yaowei Kang , Shawn Semones , Jessica Smith , Michael Frodyma
发明人： Yaowei Kang , Shawn Semones , Jessica Smith , Michael Frodyma
IPC分类号： A01N63/00 , C12N1/20
CPC分类号： C12R1/07 , A01N63/00 , A01N63/02 , C11D3/381 , C11D3/38609 , C11D3/38618 , C12N1/20 , Y10S435/832
摘要： The present disclosure relates to a strain of Bacillus amyloliquefaciens bacteria that hyperproduces amylase enzyme and protease enzyme. The strain is also suitable for producing lipase for the degradation of oleaginous materials such as fats, greases and cooking oils. The strain also has excellent fungicidal and/or fungistatic qualities. The strain of the present disclosure and the enzymes produced thereby have a number of applications, including agricultural uses, laundry and dish detergents, drain cleaners and spot removers, and among other things, baking applications.
摘要翻译：本公开涉及超生产淀粉酶和蛋白酶的解淀粉芽孢杆菌细菌菌株。该菌株也适用于生产用于脂肪，油脂和烹饪油等含油物质降解的脂肪酶。该菌株还具有优异的杀真菌和/或抑菌特性。本公开的菌株和由此产生的酶具有许多应用，包括农业用途，洗衣和洗涤剂，排水清洁剂和斑点去除剂，以及其它烘焙应用。

3. 发明授权

US08999698B2 Competitive and effective bacterial strains 有权
标题翻译：竞争有效的细菌菌株
公开(公告)号：US08999698B2
公开(公告)日：2015-04-07
申请号：US13436268
申请日：2012-03-30
申请人： Yaowei Kang , Jessica Smith , Shawn Semones , Kristi Woods
发明人： Yaowei Kang , Jessica Smith , Shawn Semones , Kristi Woods
IPC分类号： C12N1/20 , A01N63/02 , C12R1/41 , A01N63/00 , C05F11/08 , C12R1/01
CPC分类号： C05F11/08 , A01N43/16 , A01N43/90 , A01N63/00 , A01N63/02 , C12R1/01 , C12R1/41
摘要： According to the present invention new isolates of bacterial strains have been shown to possess unique properties. These bacterial strains are plant growth-promoting rhizobacterium (PGPR), posses an enhanced competitive advantage at colonizing leguminous plants, and enhance the overall performance of leguminous plant growth. Further still, the present invention discloses a novel method for screening and selecting bacterial strains having the aforementioned beneficial characteristics.
摘要翻译：根据本发明，细菌菌株的新分离物已显示具有独特的性质。这些细菌菌株是植物生长促进的根瘤菌（PGPR），在定植豆科植物方面具有更强的竞争优势，并提高豆科植物生长的整体表现。此外，本发明还公开了一种筛选和选择具有上述有益特征的细菌菌株的新方法。

4. 发明申请

US20120252672A1 Competitive and Effective Bacterial Strains 有权
标题翻译：竞争和有效的细菌菌株
公开(公告)号：US20120252672A1
公开(公告)日：2012-10-04
申请号：US13436268
申请日：2012-03-30
申请人： Yaowei Kang , Jessica Smith , Shawn Semones , Kristi Woods
发明人： Yaowei Kang , Jessica Smith , Shawn Semones , Kristi Woods
IPC分类号： A01N63/02 , A01P21/00 , C12N1/20
CPC分类号： C05F11/08 , A01N43/16 , A01N43/90 , A01N63/00 , A01N63/02 , C12R1/01 , C12R1/41
摘要： According to the present invention new isolates of bacterial strains have been shown to possess unique properties. These bacterial strains are plant growth-promoting rhizobacterium (PGPR), posses an enhanced competitive advantage at colonizing leguminous plants, and enhance the overall performance of leguminous plant growth. Further still, the present invention discloses a novel method for screening and selecting bacterial strains having the aforementioned beneficial characteristics.
摘要翻译：根据本发明，细菌菌株的新分离物已显示具有独特的性质。这些细菌菌株是植物生长促进的根瘤菌（PGPR），在定植豆科植物方面具有更强的竞争优势，并提高豆科植物生长的整体表现。此外，本发明还公开了一种筛选和选择具有上述有益特征的细菌菌株的新方法。

5. 发明公开

US20230248616A1 Pacifier Fabrication Method 审中-公开
公开(公告)号：US20230248616A1
公开(公告)日：2023-08-10
申请号：US18135512
申请日：2023-04-17
申请人： Jessica Smith
发明人： Jessica Smith
IPC分类号： A61J17/00
CPC分类号： A61J17/001 , A61J17/105
摘要： A method for fabricating a pacifier having surface features replicating those of a nursing mother's nipple, wherein the nipple has a length, the method including steps of utilizing the nursing mother's nipple as a positive mold to cast a first negative mold; utilizing the first negative mold to cast a replica of the nursing mother's nipple; modifying the replica of the nursing mother's nipple so that said replica has a length greater than that of the nursing mother's nipple; utilizing the modified replica of the nursing mother's nipple as a second positive mold to cast a second negative mold; and utilizing the second negative mold to cast an extended length replica of the nursing mother's nipple.

6. 发明申请

US20090053451A1 DECORATIVE COVERINGS FOR ORTHOPEDIC SUPPORT 审中-公开
标题翻译：用于正确支持的装饰性覆盖物
公开(公告)号：US20090053451A1
公开(公告)日：2009-02-26
申请号：US12197846
申请日：2008-08-25
申请人： Jessica Smith
发明人： Jessica Smith
IPC分类号： B32B38/10 , B32B33/00
CPC分类号： B44C1/1712 , Y10T428/1486 , Y10T428/24802
摘要： A decorative covering is provided for application to an exterior portion of an orthopedic support, Such an orthopedic support may be a cast made out of a curable resin impregnated fabric or any other orthopedic support known in the art. In one embodiment, the decorative covering may be formed on an at least partially translucent thermally deformable sheet member. In this embodiment a design layer may be printed on the sheet member such that the design layer makes up a decorative design. The sheet member may be applied to the orthopedic support using an adhesive applied to a side of the sheet member opposite the side on which the design layer is printed. Once initially adhered, the sheet member may be thermally deformed to at least partially conform to the contours of the underlying orthopedic support. In one embodiment, the sheet member has a pre-applied adhesive along with a release liner that covers the adhesive.
摘要翻译：提供了用于矫形外科支架外部的装饰性覆盖物。这种整形外科支架可以是由可固化树脂浸渍织物或本领域已知的任何其它矫形支架制成的铸件。在一个实施例中，装饰性覆盖物可以形成在至少部分半透明的可热变形的片状构件上。在该实施例中，设计层可以印刷在片材上，使得设计层构成装饰设计。片材可以使用施加到片材的与印刷设计层相对的一侧的粘合剂施加到整形外科支架上。一旦最初粘附，片材构件可以被热变形以至少部分地符合下面的整形外科支架的轮廓。在一个实施例中，片材具有预先施加的粘合剂以及覆盖粘合剂的剥离衬垫。

7. 发明申请

US20170146519A1 STING AGONISTS AND METHODS OF SELECTING STING AGONISTS 审中-公开
公开(公告)号：US20170146519A1
公开(公告)日：2017-05-25
申请号：US15357685
申请日：2016-11-21
申请人： Victor DeFilippis , Tina Sali , Kara Pryke , Jinu Abraham , Andrew Liu , Iris Archer , Kayla Sheridan , Aaron Nilsen , Rebecca Broeckel , Jessica Smith , Lisi Amsler , Daniel Streblow , Andrew Placzek
发明人： Victor DeFilippis , Tina Sali , Kara Pryke , Jinu Abraham , Andrew Liu , Iris Archer , Kayla Sheridan , Aaron Nilsen , Rebecca Broeckel , Jessica Smith , Lisi Amsler , Daniel Streblow , Andrew Placzek
IPC分类号： G01N33/50 , C07D279/16 , C07D417/12
CPC分类号： G01N33/5041 , A61K31/5415 , C07D279/16 , C07D417/12 , G01N2333/705 , Y02A50/382
摘要： Disclosed are small molecules capable of activating the type I interferon (IFN) response by way of the transcription factor IFN regulatory factor 3 (IRF3) were identified. A high throughput in vitro screen yielded 4-(2-chloro-6-fluorobenzyl)-N-(furan-2-ylmethyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (referred to herein as G10), which was found to trigger IRF3/IFN-associated transcription in human fibroblasts. To define cellular proteins essential to elicitation of the antiviral activity by the compound a reverse genetics approach that utilized genome editing via CRISPR/Cas9 technology was employed. This allowed the identification of IRF3, the IRF3-activating adaptor molecule STING, and the IFN-associated transcription factor STAT1 as required for observed gene induction and antiviral effects.

8. 发明授权

US08585500B2 Game apparatus 有权
标题翻译：游戏机
公开(公告)号：US08585500B2
公开(公告)日：2013-11-19
申请号：US12629765
申请日：2009-12-02
申请人： Jessica Smith , Soon Park
发明人： Jessica Smith , Soon Park
IPC分类号： A63F9/24 , A63F13/00 , G06F17/00 , G06F19/00
CPC分类号： A63F9/24 , A63F3/00895 , A63F2009/2411 , A63F2009/2413 , A63F2009/2414 , A63F2009/2419 , A63F2009/242 , A63F2009/2432 , A63F2009/247
摘要： A game apparatus that includes a processor, a microphone, a memory, a speaker, and an audio playback actuator. The memory stores a first plurality of audio messages, each corresponding to an audio input received by the microphone, and a second plurality of pre-recorded audio messages. The audio playback actuator causes the processor to randomly select a first audio message from the first plurality of audio messages and a second audio message from the second plurality of pre-recorded audio messages, and to play the first and second audio messages through the speaker.
摘要翻译：包括处理器，麦克风，存储器，扬声器和音频回放致动器的游戏装置。存储器存储第一多个音频消息，每个音频消息对应于由麦克风接收的音频输入和第二多个预先记录的音频消息。音频播放执行器使得处理器从第一多个音频消息中随机选择第一音频消息，并从第二多个预先录制的音频消息中随机选择第二音频消息，并通过扬声器播放第一和第二音频消息。

9. 发明申请

US20110130202A1 GAME APPARATUS 有权
标题翻译：游戏装置
公开(公告)号：US20110130202A1
公开(公告)日：2011-06-02
申请号：US12629765
申请日：2009-12-02
申请人： Jessica Smith , Soon Park
发明人： Jessica Smith , Soon Park
IPC分类号： A63F9/24
CPC分类号： A63F9/24 , A63F3/00895 , A63F2009/2411 , A63F2009/2413 , A63F2009/2414 , A63F2009/2419 , A63F2009/242 , A63F2009/2432 , A63F2009/247
摘要： A game apparatus that includes a processor, a microphone, a memory, a speaker, and an audio playback actuator. The memory stores a first plurality of audio messages, each corresponding to an audio input received by the microphone, and a second plurality of pre-recorded audio messages. The audio playback actuator causes the processor to randomly select a first audio message from the first plurality of audio messages and a second audio message from the second plurality of pre-recorded audio messages, and to play the first and second audio messages through the speaker.
摘要翻译：包括处理器，麦克风，存储器，扬声器和音频回放致动器的游戏装置。存储器存储第一多个音频消息，每个音频消息对应于由麦克风接收的音频输入和第二多个预先记录的音频消息。音频播放执行器使得处理器从第一多个音频消息中随机选择第一音频消息，并从第二多个预先录制的音频消息中随机选择第二音频消息，并通过扬声器播放第一和第二音频消息。

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