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1. 发明授权

US09066657B2 Methods and systems of optical imaging for target detection in a scattering medium 有权
标题翻译：散射介质中目标检测的光学成像方法和系统
公开(公告)号：US09066657B2
公开(公告)日：2015-06-30
申请号：US12952359
申请日：2010-11-23
申请人： Siavash Yazdanfar , Floribertus Heukensfeldt Jansen , Stephen Lomnes , Xinghua Wang
发明人： Siavash Yazdanfar , Floribertus Heukensfeldt Jansen , Stephen Lomnes , Xinghua Wang
IPC分类号： G06K9/40 , F21V9/16 , G01J1/58 , G01T1/10 , G21H3/02 , G21K5/00 , H01J65/06 , H01J65/08 , H01L27/00 , G01N21/86 , G01V8/00 , A61B5/00
CPC分类号： A61B5/0059 , A61B5/0064
摘要： A method for enhancing contrast in fluorescence imaging is provided. The method comprises providing a patterned illumination source for illuminating one or more regions corresponding to a scan step, scanning at least a portion of a surface of a subject using a plurality of scan steps, acquiring image frames corresponding to two or more scan steps, deducting a background fluorescence from the image frames corresponding to the two or more scan steps to form one or more processed image frames, and reconstructing an image using one or more of the processed image frames.
摘要翻译：提供了一种增强荧光成像对比度的方法。该方法包括提供用于照亮与扫描步骤相对应的一个或多个区域的图案化照明源，使用多个扫描步骤扫描对象的表面的至少一部分，获取对应于两个或更多个扫描步骤的图像帧，扣除来自对应于两个或更多个扫描步骤的图像帧的背景荧光，以形成一个或多个经处理的图像帧，以及使用一个或多个处理后的图像帧重建图像。

2. 发明申请

US20090290236A1 ENDOSCOPE OBJECTIVE LENS WITH LARGE ENTRANCE PUPIL DIAMETER AND HIGH NUMERICAL APERTURE 有权
标题翻译：内窥镜具有大的入口直径和高数值孔径的目镜
公开(公告)号：US20090290236A1
公开(公告)日：2009-11-26
申请号：US12125512
申请日：2008-05-22
申请人： Xinghua Wang , Siavash Yazdanfar
发明人： Xinghua Wang , Siavash Yazdanfar
IPC分类号： G02B13/04
CPC分类号： G02B23/243
摘要： An endoscope objective lens for collecting combined bright field (white light) and fluorescence images includes a negative lens group, a stop, and a positive lens group. The lens has a combination of large entrance pupil diameter (≧0.4 mm) for efficiently collecting weak fluorescence light, large ratio between the entrance pupil diameter and the maximum outside diameter (Dentrance/Dmax larger than 0.2), large field of view (FFOV≧120°) and favorably corrected spherical, lateral chromatic and Petzval field curvature for both visible and near infrared wavelengths.
摘要翻译：用于收集组合亮场（白光）和荧光图像的内窥镜物镜包括负透镜组，光阑和正透镜组。透镜具有大的入射光瞳直径（> = 0.4mm）的组合，用于有效地收集弱荧光，入射光瞳直径与最大外径之比大（Dentrance / Dmax大于0.2），大视野（FFOV > = 120°），并且对于可见光和近红外波长都有良好校正的球面，横向色度和Petzval场曲率。

3. 发明申请

US20080088844A1 Method and apparatus for a microscope image selector 有权
公开(公告)号：US20080088844A1
公开(公告)日：2008-04-17
申请号：US11902874
申请日：2007-09-26
申请人： Xinghua Wang , Thomas Voigt , David Tuschel , Chenhui Wang , Patrick Treado
发明人： Xinghua Wang , Thomas Voigt , David Tuschel , Chenhui Wang , Patrick Treado
IPC分类号： G01N21/25
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0291 , G01J3/36 , G01J3/44 , G01N21/359 , G01N21/59 , G01N21/6458 , G01N2021/6419 , G01N2021/6421 , G01N2021/656
摘要： The disclosure generally relates to a multimode imaging apparatus for simultaneously obtaining multiple wavelength-discriminative spectral images of a sample. In one embodiment, the apparatus includes an image selector having a rotator assembly, the rotator assembly housing a first plurality of optical components, the image selector adapted to receive a illuminating photons having a first wavelength and direct the illuminating photons to the sample, the image selector adapted to receive illuminating photons interacted with the sample and selectively direct said interacted photons to one of a plurality of detection sources; a microscope turret housing a second plurality of components, the microscope turret adapted to receive illuminating photons having a second wavelength and direct the photons to the sample; the microscopic turret adapted to receive illuminating photons interacted with the sample and selectively direct said interacted photons to one of a plurality of detection sources; wherein substantially all of the interacted photons are selectively directed one of a plurality of detection sources to form multiple wavelength discriminative spectral images of the sample simultaneously.

4. 发明申请

US20080007813A1 MULTI-CONJUGATE LIQUID CRYSTAL TUNABLE FILTER 有权
标题翻译：多串联液晶可调滤波器
公开(公告)号：US20080007813A1
公开(公告)日：2008-01-10
申请号：US11112654
申请日：2005-04-22
申请人： Xinghua Wang , Chenhui Wang
发明人： Xinghua Wang , Chenhui Wang
IPC分类号： G02F1/03
CPC分类号： G02B5/28 , G02B27/288 , G02F1/13473 , G02F1/1393 , G02F2202/40 , G02F2203/055
摘要： A hyper-spectral imaging filter has serial stages along an optical signal path with angularly distributed birefringent retarders and polarizers forming interference filters. The retarders can include tunable birefringent elements such as liquid crystals controlled in unison, fixed retarders and/or combined tunable and fixed birefringences. Distinctly different periodic transmission spectra are provided by different filter stages, each having multiple retarders, in particular with some stages having broad bandpass peaks at wide spectral spacing and other stages have very narrow closely spaced peaks. The respective spectra include at least one tunably selectable band at which the transmission spectra of the filter stages coincide, whereby the salutary narrow bandpass and wide spectral spacing ranges of different stages apply together, resulting in a high finesse wavelength filter suitable for spectral imaging.
摘要翻译：超光谱成像滤光器沿着具有角分布的双折射延迟器和形成干涉滤光器的偏振器的光信号路径具有串联级。延迟器可以包括可调谐的双折射元件，例如一致控制的液晶，固定延迟器和/或组合的可调谐和固定的双折射。不同的过滤阶段提供了不同的周期透射光谱，每个滤光片具有多个延迟器，特别是在宽光谱间隔处具有宽带通峰的一些阶段，其他阶段具有非常窄的紧密间隔的峰。各个频谱包括至少一个可调谐可选择的频带，滤波器级的传输频谱在该频带处重合，由此不同阶段的有益窄带通和宽频谱间隔范围一起应用，导致适合于光谱成像的高精细波长滤波器。

5. 发明授权

US07283241B2 Method and apparatus for a microscope image selector 有权
标题翻译：显微镜图像选择器的方法和装置
公开(公告)号：US07283241B2
公开(公告)日：2007-10-16
申请号：US11045080
申请日：2005-01-31
申请人： Xinghua Wang , Thomas C. Voigt , David Tuschel , Chenhui Wang , Patrick J. Treado
发明人： Xinghua Wang , Thomas C. Voigt , David Tuschel , Chenhui Wang , Patrick J. Treado
IPC分类号： G01N21/25
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0291 , G01J3/36 , G01J3/44 , G01N21/359 , G01N21/59 , G01N21/6458 , G01N2021/6419 , G01N2021/6421 , G01N2021/656
摘要： The disclosure generally relates to a multimode imaging apparatus for simultaneously obtaining multiple wavelength-discriminative spectral images of a sample. In one embodiment, the apparatus includes an image selector having a rotator assembly, the rotator assembly housing a first plurality of optical components, the image selector adapted to receive a illuminating photons having a first wavelength and direct the illuminating photons to the sample, the image selector adapted to receive illuminating photons interacted with the sample and selectively direct said interacted photons to one of a plurality of detection sources; a microscope turret housing a second plurality of components, the microscope turret adapted to receive illuminating photons having a second wavelength and direct the photons to the sample; the microscopic turret adapted to receive illuminating photons interacted with the sample and selectively direct said interacted photons to one of a plurality of detection sources; wherein substantially all of the interacted photons are selectively directed one of a plurality of detection sources to form multiple wavelength discriminative spectral images of the sample simultaneously.
摘要翻译：本公开总体上涉及用于同时获得样本的多个波长鉴别光谱图像的多模式成像装置。在一个实施例中，该装置包括具有旋转器组件的图像选择器，旋转体组件容纳第一多个光学部件，图像选择器适于接收具有第一波长的照明光子并将照射光子引导到样本，图像选择器，适于接收与样本相互作用的照明光子，并选择性地将所述相互作用的光子引导到多个检测源之一; 显微镜转台，其容纳第二多个部件，所述显微镜转台适于接收具有第二波长并且将所述光子引导到所述样品的照明光子; 适于接收与样品相互作用的照明光子并且选择性地将所述相互作用的光子引导到多个检测源中的一个的微观炮塔; 其中基本上所有相互作用的光子被选择性地指向多个检测源中的一个，以同时形成样品的多个波长鉴别光谱图像。

6. 发明申请

US20070166045A1 BIREFRINGENT SPECTRAL FILTER WITH WIDE FIELD OF VIEW AND ASSOCIATED COMMUNICATIONS METHOD AND APPARATUS 有权
标题翻译：具有宽视场和相关通信方法和设备的双向光谱滤波器
公开(公告)号：US20070166045A1
公开(公告)日：2007-07-19
申请号：US11621166
申请日：2007-01-09
申请人： Xinghua Wang
发明人： Xinghua Wang
IPC分类号： H04B10/00
CPC分类号： G02F1/13473 , G02B27/283 , G02F1/13318 , G02F1/133526 , G02F1/13363 , G02F1/1347 , G02F1/21 , G02F2202/40 , G02F2203/01 , G02F2203/18
摘要： A spectral filter is adapted for use in a receiver, for example in a short range submarine laser signal path, wherein the relative orientations of the receiver is such that the signal may appear diffusely or at an unknown point in a wide external field of view around an optical axis of the receiver. A narrow band spectral filter in the receiver has cascaded stages of tunable retarders with includes multi-conjugate stages that tolerate light that is oblique to normal, up to a diverging internal field of view angle up to about 10°. A fisheye lens assembly refracts incoming light from a wider external field of 170° or more and directs the light into the filter over the narrow internal field of view. Calibration and feedback control can be provided to stabilize the discriminated wavelength peak, which remains at the same center wavelength over the span of the internal field of view notwithstanding the difference in retarder thicknesses traversed along paths that are normal to the retarders versus oblique to the optical axis.
摘要翻译：频谱滤波器适于在接收机中使用，例如在短距离海底激光信号路径中，其中接收机的相对取向使得信号可以在广泛的外部视野周围扩散地或处于未知点处接收机的光轴。接收机中的窄带光谱滤波器具有级联的可调谐延迟器，其包括多个共轭级，其允许倾斜于正常的光，直到高达约10°的发散内部视场角。鱼眼镜头组件从170°以上的较宽外部场景折射入射光，并将光引导到狭窄的内部视场内的过滤器中。可以提供校准和反馈控制来稳定鉴别波长峰值，其在内部视野的跨度上保持在相同的中心波长，尽管沿着与延迟器相对的路径相对于延迟器相对于相对于光学器件倾斜的路径穿过的延迟器厚度的差异轴。

7. 发明授权

US08248905B2 Method of parallel bit-wise holographic data storage source using a parallel light source 有权
标题翻译：使用平行光源的并行位扫描全息数据存储源的方法
公开(公告)号：US08248905B2
公开(公告)日：2012-08-21
申请号：US12905853
申请日：2010-10-15
申请人： Xinghua Wang , Xiaolei Shi , Hua Xia , Victor Petrovich Ostroverkhov
发明人： Xinghua Wang , Xiaolei Shi , Hua Xia , Victor Petrovich Ostroverkhov
IPC分类号： G11B7/00
CPC分类号： G11B7/268 , G02B6/3624 , G02B6/3652 , G02B6/368 , G11B7/00781 , G11B7/1384
摘要： The present techniques provide techniques for outputting counter-propagating parallel light waves to pre-record a holographic data disk. The parallel light waves are transmitted through a holographic system via a fiber optic bundle including a plurality of polarization-maintaining (PM) optical fibers. Each of the PM optical fibers in the fiber optic bundle may have one or more of a different wavelength, a different coherence length, and a different polarization orientation to reduce crosstalk in the disk. Furthermore, the fiber optic bundle array is rotated to produce interference spots indicative of micro-holograms according to the data track pitch of the holographic disk over which the fiber optic bundle is outputting the light waves.
摘要翻译：本技术提供了用于输出反向传播的平行光波以预先记录全息数据盘的技术。平行光波通过包括多个偏振维持（PM）光纤的光纤束通过全息系统传输。光纤束中的每个PM光纤可以具有不同波长，不同相干长度和不同偏振方向中的一个或多个，以减少盘中的串扰。此外，光纤束阵列旋转以根据光纤束在其上输出光波的全息光盘的数据轨道间距产生指示微全息图的干涉斑点。

8. 发明授权

US08169696B2 Systems for intraoperative nerve imaging 有权
标题翻译：术中神经成像系统
公开(公告)号：US08169696B2
公开(公告)日：2012-05-01
申请号：US12821731
申请日：2010-06-23
申请人： Siavash Yazdanfar , Cristina Abucay Tan Hehir , Xinghua Wang
发明人： Siavash Yazdanfar , Cristina Abucay Tan Hehir , Xinghua Wang
IPC分类号： G02B21/06 , G02B27/02 , A61B6/00
CPC分类号： A61K49/0021
摘要： Disclosed are systems for intraoperative nerve imaging using compact high collection power imaging devices for fluorescence and white light imaging of myelin basic protein (MBP) nerve imaging agents during open and minimally invasive surgery.
摘要翻译：公开了使用紧凑型高收集功率成像装置的用于术中神经成像的系统，用于在开放和微创手术期间的髓磷脂碱性蛋白（MBP）神经成像剂的荧光和白光成像。

9. 发明申请

US20120092979A1 METHOD OF PARALLEL BIT-WISE HOLOGRAPHIC DATA STORAGE USING A PARALLEL LIGHT SOURCE 有权
标题翻译：使用并行光源并行双向全息数据存储的方法
公开(公告)号：US20120092979A1
公开(公告)日：2012-04-19
申请号：US12905853
申请日：2010-10-15
申请人： Xinghua Wang , Xiaolei Shi , Hua Xia , Victor Petrovich Ostroverkhov
发明人： Xinghua Wang , Xiaolei Shi , Hua Xia , Victor Petrovich Ostroverkhov
IPC分类号： G11B7/00
CPC分类号： G11B7/268 , G02B6/3624 , G02B6/3652 , G02B6/368 , G11B7/00781 , G11B7/1384
摘要： The present techniques provide techniques for outputting counter-propagating parallel light waves to pre-record a holographic data disk. The parallel light waves are transmitted through a holographic system via a fiber optic bundle including a plurality of polarization-maintaining (PM) optical fibers. Each of the PM optical fibers in the fiber optic bundle may have one or more of a different wavelength, a different coherence length, and a different polarization orientation to reduce crosstalk in the disk. Furthermore, the fiber optic bundle array is rotated to produce interference spots indicative of micro-holograms according to the data track pitch of the holographic disk over which the fiber optic bundle is outputting the light waves.
摘要翻译：本技术提供了用于输出反向传播的平行光波以预先记录全息数据盘的技术。平行光波通过包括多个偏振维持（PM）光纤的光纤束通过全息系统传输。光纤束中的每个PM光纤可以具有不同波长，不同相干长度和不同偏振方向中的一个或多个，以减少盘中的串扰。此外，光纤束阵列旋转以根据光纤束在其上输出光波的全息光盘的数据轨道间距产生指示微全息图的干涉斑点。

10. 发明申请

US20110168241A1 Photo-Voltaic Power Generation Equipment that Can Automatically Track the Sun 有权
标题翻译：可以自动跟踪太阳的光伏发电设备
公开(公告)号：US20110168241A1
公开(公告)日：2011-07-14
申请号：US12995629
申请日：2009-01-04
申请人： Xinghua Wang
发明人： Xinghua Wang
IPC分类号： H01L31/02
CPC分类号： H02S20/32 , F24S25/13 , F24S30/452 , F24S2025/02 , F24S2030/134 , Y02E10/47
摘要： This invention relates to a type of solar energy photo-voltaic power generation equipment that can automatically track the sun. This device includes a pedestal installed on a mounting platform. On the pedestal, a main support frame is provided. On the support frame, a solar cell panel platform is provided. On this platform, a solar energy photo-voltaic assembly is installed. The pedestal is connected to the mounting platform and can rotate relative to the mounting platform. On the pedestal, a circumferentially driven planet reduction gear is installed. On the main support frame, a platform elevation angle adjustment lifter is installed. The end of the telescopic link on the lifter is hinged to the solar cell panel platform. The circumferentially driven planet reduction gear and platform elevation angle adjustment lifter are connected to an electric control device.
摘要翻译：本发明涉及一种能够自动跟踪太阳的太阳能光电发电设备。该装置包括安装在安装平台上的基座。在基座上，提供主支架。在支撑框架上，提供太阳能电池板平台。在这个平台上，安装了一个太阳能光伏组件。基座连接到安装平台，并可相对于安装平台旋转。在基座上安装有周向驱动的行星减速齿轮。在主支架上安装了平台仰角调节升降器。升降机上的伸缩连杆的端部铰接到太阳能电池板平台。周向驱动的行星减速齿轮和平台仰角调节升降器连接到电气控制装置。

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