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    • 1. 发明授权
    • CNGH0010 specific polynucleotides, polypeptides, antibodies, compositions, methods and uses
    • CNGH0010特异性多核苷酸,多肽,抗体,组合物,方法和用途
    • US07479479B2
    • 2009-01-20
    • US11680113
    • 2007-02-28
    • Xiao-yu R. SongChong HuangKeying MaBailin LiangMichael Naso
    • Xiao-yu R. SongChong HuangKeying MaBailin LiangMichael Naso
    • C07K14/00
    • C07K14/47A61K38/00A61K45/06A61K2039/505C07K16/18C07K2317/92C12Q1/6883C12Q2600/158
    • Novel polypeptides (CNGH0010) and antibodies, including specified portions or variants, specific for at least one such CNGH0010 polypeptide, variant, or fragment thereof, as well as nucleic acids encoding such CNGH0010 polypeptides and antibodies, complementary nucleic acids, vectors, host cells, and methods of making and using thereof, are useful for therapeutic and diagnostic formulations, administration and devices. The aforesaid polypeptides can be used to generate human, primate, rodent, mammalian, chimeric, humanized and/or CDR-grafted anti-CNGH0010 antibodies. The CNGH0010 polypeptides and antibodies are used in modulating or treating at least one CNGH0010-related disease in a cell, tissue, organ, animal, or patient. Such diseases may include, but are not limited to, psoriasis, rheumatoid arthritis, emphysema, asthma, diabetes, autoimmune thyroiditis, inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, different types of dermatitis including allergic dermatitis, contact dermatitis, actinic keratosis, wound healing, scar formation, various renal diseases, various respiratory diseases, various diseases of reproductive organs, such as endometriosis, melanoma, squamous cell carcinoma, ovarian cancer, breast cancer, lung cancer, colon cancer, prostate cancer, renal cell carcinoma, Grave's diseases and other inflammatory and hyperproliferative diseases.
    • 对于至少一个这样的CNGH0010多肽,其变体或片段,以及编码这样的CNGH0010多肽和抗体,互补核酸,载体,宿主细胞的核酸,对于至少一个这样的CNGH0010多肽,变体或其片段特异的新型多肽(CNGH0010)和抗体,包括特定部分或变体, 其制备和使用方法可用于治疗和诊断制剂,给药和装置。 上述多肽可用于产生人,灵长类动物,啮齿动物,哺乳动物,嵌合,人源化和/或CDR移植抗CNGH0010抗体。 CNGH0010多肽和抗体用于调节或治疗细胞,组织,器官,动物或患者中的至少一种CNGH0010相关疾病。 这些疾病可以包括但不限于牛皮癣,类风湿性关节炎,肺气肿,哮喘,糖尿病,自身免疫性甲状腺炎,包括克罗恩病和溃疡性结肠炎在内的炎性肠病,不同类型的皮炎,包括过敏性皮炎,接触性皮炎,光化性角化病, 伤口愈合,瘢痕形成,各种肾脏疾病,各种呼吸道疾病,生殖器官的各种疾病,如子宫内膜异位症,黑素瘤,鳞状细胞癌,卵巢癌,乳腺癌,肺癌,结肠癌,前列腺癌,肾细胞癌,Grave's 疾病等炎症和过度增生性疾病。
    • 2. 发明申请
    • CNGH0010 Specific Polynucleotides, Polypeptides, Antibodies, Compositions, Methods and Uses
    • CNGH0010特异性多核苷酸,多肽,抗体,组合物,方法和用途
    • US20090137783A1
    • 2009-05-28
    • US12352881
    • 2009-01-13
    • Xiao-yu R. SongChong HuangKeying MaBailin LiangMichael Naso
    • Xiao-yu R. SongChong HuangKeying MaBailin LiangMichael Naso
    • C07K16/18C07K14/00
    • C07K14/47A61K38/00A61K45/06A61K2039/505C07K16/18C07K2317/92C12Q1/6883C12Q2600/158
    • Novel polypeptides (CNGH0010) and antibodies, including specified portions or variants, specific for at least one such CNGH0010 polypeptide, variant, or fragment thereof, as well as nucleic acids encoding such CNGH0010 polypeptides and antibodies, complementary nucleic acids, vectors, host cells, and methods of making and using thereof, are useful for therapeutic and diagnostic formulations, administration and devices. The aforesaid polypeptides can be used to generate human, primate, rodent, mammalian, chimeric, humanized and/or CDR-grafted anti-CNGH0010 antibodies. The CNGH0010 polypeptides and antibodies are used in modulating or treating at least one CNGH0010-related disease in a cell, tissue, organ, animal, or patient. Such diseases may include, but are not limited to, psoriasis, rheumatoid arthritis, emphysema, asthma, diabetes, autoimmune thyroiditis, inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, different types of dermatitis including allergic dermatitis, contact dermatitis, actinic keratosis, wound healing, scar formation, various renal diseases, various respiratory diseases, various diseases of reproductive organs, such as endometriosis, melanoma, squamous cell carcinoma, ovarian cancer, breast cancer, lung cancer, colon cancer, prostate cancer, renal cell carcinoma, Grave's diseases and other inflammatory and hyperproliferative diseases.
    • 对于至少一个这样的CNGH0010多肽,其变体或片段,以及编码这样的CNGH0010多肽和抗体,互补核酸,载体,宿主细胞的核酸,对于至少一个这样的CNGH0010多肽,变体或其片段特异的新型多肽(CNGH0010)和抗体,包括特定部分或变体, 其制备和使用方法可用于治疗和诊断制剂,给药和装置。 上述多肽可用于产生人,灵长类动物,啮齿动物,哺乳动物,嵌合,人源化和/或CDR移植抗CNGH0010抗体。 CNGH0010多肽和抗体用于调节或治疗细胞,组织,器官,动物或患者中的至少一种CNGH0010相关疾病。 这些疾病可以包括但不限于牛皮癣,类风湿性关节炎,肺气肿,哮喘,糖尿病,自身免疫性甲状腺炎,包括克罗恩病和溃疡性结肠炎在内的炎性肠病,不同类型的皮炎,包括过敏性皮炎,接触性皮炎,光化性角化病, 伤口愈合,瘢痕形成,各种肾脏疾病,各种呼吸道疾病,生殖器官的各种疾病,如子宫内膜异位症,黑素瘤,鳞状细胞癌,卵巢癌,乳腺癌,肺癌,结肠癌,前列腺癌,肾细胞癌,Grave's 疾病等炎症和过度增生性疾病。
    • 3. 发明申请
    • CNGH0010 Specific Polynucleotides, Polypeptides, Antibodies, Compositions, Methods and Uses
    • CNGH0010特异性多核苷酸,多肽,抗体,组合物,方法和用途
    • US20080044422A1
    • 2008-02-21
    • US11680113
    • 2007-02-28
    • Xiao-yu SongChong HuangKeying MaBailin LiangMichael Naso
    • Xiao-yu SongChong HuangKeying MaBailin LiangMichael Naso
    • A61K31/70A01K67/00A61K38/00A61K39/395A61P43/00C07K14/00C07K16/18C12N1/00C12N1/20C12N15/00C12N15/11C12N15/82C12N5/06C12P21/04C12Q1/68G01N33/00
    • C07K14/47A61K38/00A61K45/06A61K2039/505C07K16/18C07K2317/92C12Q1/6883C12Q2600/158
    • Novel polypeptides (CNGH0010) and antibodies, including specified portions or variants, specific for at least one such CNGH0010 polypeptide, variant, or fragment thereof, as well as nucleic acids encoding such CNGH0010 polypeptides and antibodies, complementary nucleic acids, vectors, host cells, and methods of making and using thereof, are useful for therapeutic and diagnostic formulations, administration and devices. The aforesaid polypeptides can be used to generate human, primate, rodent, mammalian, chimeric, humanized and/or CDR-grafted anti-CNGH0010 antibodies. The CNGH0010 polypeptides and antibodies are used in modulating or treating at least one CNGH0010-related disease in a cell, tissue, organ, animal, or patient. Such diseases may include, but are not limited to, psoriasis, rheumatoid arthritis, emphysema, asthma, diabetes, autoimmune thyroiditis, inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, different types of dermatitis including allergic dermatitis, contact dermatitis, actinic keratosis, wound healing, scar formation, various renal diseases, various respiratory diseases, various diseases of reproductive organs, such as endometriosis, melanoma, squamous cell carcinoma, ovarian cancer, breast cancer, lung cancer, colon cancer, prostate cancer, renal cell carcinoma, Grave's diseases and other inflammatory and hyperproliferative diseases.
    • 对于至少一个这样的CNGH0010多肽,其变体或片段,以及编码这样的CNGH0010多肽和抗体,互补核酸,载体,宿主细胞的核酸,对于至少一个这样的CNGH0010多肽,变体或其片段特异的新型多肽(CNGH0010)和抗体,包括特定部分或变体, 其制备和使用方法可用于治疗和诊断制剂,给药和装置。 上述多肽可用于产生人,灵长类动物,啮齿动物,哺乳动物,嵌合,人源化和/或CDR移植抗CNGH0010抗体。 CNGH0010多肽和抗体用于调节或治疗细胞,组织,器官,动物或患者中的至少一种CNGH0010相关疾病。 这些疾病可以包括但不限于牛皮癣,类风湿性关节炎,肺气肿,哮喘,糖尿病,自身免疫性甲状腺炎,包括克罗恩病和溃疡性结肠炎在内的炎性肠病,不同类型的皮炎,包括过敏性皮炎,接触性皮炎,光化性角化病, 伤口愈合,瘢痕形成,各种肾脏疾病,各种呼吸道疾病,生殖器官的各种疾病,如子宫内膜异位症,黑素瘤,鳞状细胞癌,卵巢癌,乳腺癌,肺癌,结肠癌,前列腺癌,肾细胞癌,Grave's 疾病等炎症和过度增生性疾病。
    • 6. 发明授权
    • Flat panel display device, stereoscopic display device, and plasma display device
    • 平板显示装置,立体显示装置和等离子体显示装置
    • US08988629B2
    • 2015-03-24
    • US13381918
    • 2011-11-24
    • Yi-Cheng KuoYu-Chun HsiaoChong HuangJia-He ChengCheng-Wen QueQuan LiLiu-Yang Yang
    • Yi-Cheng KuoYu-Chun HsiaoChong HuangJia-He ChengCheng-Wen QueQuan LiLiu-Yang Yang
    • G02F1/1333H05K5/02H05K9/00
    • H05K5/02H05K9/0054
    • The present invention provides a flat panel display device, which includes a backlight system and a display panel. The backlight system includes a light source, a light homogenization mechanism, and a back frame. The back frame carries the light source and the light homogenization mechanism, and the light homogenization mechanism guides light from the light source into the display panel. The back frame includes primary assembling pieces, secondary assembling pieces, and a bracing piece for fixing a circuit board. The back frame includes a reinforcement structure formed on a joint section of a primary assembling piece so as to make the overall strength of the back frame meeting the required strength. The bracing piece includes a bracing body, a first suspension section, a first bearing section, and a first resilient bent section and the bracing piece overcomes the problem that a circuit board cannot be easily fixed. The present invention also provides a stereoscopic display device and a plasma display device. The present invention has a back frame having a simple structure, reduces the expenditure of the back frame mold, and also saves the material used for back frame so as to lower down the cost of flat panel display device.
    • 本发明提供一种平板显示装置,其包括背光系统和显示面板。 背光系统包括光源,光匀化机构和后框架。 后框架承载光源和光均化机构,光均化机构将来自光源的光引导到显示面板。 后框架包括主要组装件,辅助组装件和用于固定电路板的支撑件。 后框架包括形成在主要组装件的接合部分上的加强结构,以使后框架的整体强度达到所需的强度。 支撑件包括支撑体,第一悬挂部分,第一轴承部分和第一弹性弯曲部分,并且支撑件克服了电路板不容易固定的问题。 本发明还提供一种立体显示装置和等离子体显示装置。 本发明具有结构简单的后框架,减少了背框模具的耗费,并且还节省了用于后框架的材料,从而降低了平板显示装置的成本。
    • 7. 发明授权
    • Back frame and backlight system
    • 背框和背光系统
    • US08913210B2
    • 2014-12-16
    • US13381915
    • 2011-11-23
    • Yi-Cheng KuoYu-Chun HsiaoChong HuangJia-He ChengCheng-Wen QueQuan LiLiu-Yang Yang
    • Yi-Cheng KuoYu-Chun HsiaoChong HuangJia-He ChengCheng-Wen QueQuan LiLiu-Yang Yang
    • G02F1/1333H05K9/00H04N5/64H05K5/02
    • H04N5/64H05K5/02H05K9/0054
    • The present invention provides a back frame of flat panel display device, which includes primary assembling pieces, secondary assembling pieces, and a bracing piece for fixing a circuit board. The primary assembling pieces have a number of at least two, and the at least two primary assembling pieces are connected through joining. The secondary assembling pieces are joined to the primary assembling pieces. The bracing piece includes a bracing body, a first suspension section, a first bearing section, and a first resilient bent section. The bracing body is mounted to the primary assembling pieces or the secondary assembling pieces or is mounted to both the primary assembling pieces and the secondary assembling pieces. The available mounting points between the bracing body and the primary assembling pieces or the secondary assembling pieces are of a number of at least two. The bracing piece fixes a circuit board. The present invention also provides a backlight system. The back frame and the backlight system of the present invention have a back frame mold having a simple structure, reduce the expenditure of a back frame mold, and save the material used for back frame so as to lower down the cost of flat panel display device.
    • 本发明提供一种平板显示装置的后框架,其包括一次装配件,二次装配件和用于固定电路板的支撑件。 主组装件具有至少两个,并且至少两个主要组装件通过接合连接。 二次组装件连接到主组装件。 支撑件包括支撑体,第一悬挂部分,第一支承部分和第一弹性弯曲部分。 支撑体安装在主组装件或二次组装件上,或者安装在主组装件和辅组件上。 支撑体和主组装件或辅助组装件之间的可用安装点至少有两个。 支撑件固定电路板。 本发明还提供一种背光系统。 本发明的后框架和背光系统具有结构简单的后框架模具,减少了背框模具的消耗,并且节省了用于后框架的材料,以降低平板显示装置的成本 。
    • 8. 发明授权
    • Flat panel display device, stereoscopic display device, and plasma display device
    • 平板显示装置,立体显示装置和等离子体显示装置
    • US08896785B2
    • 2014-11-25
    • US13381922
    • 2011-11-24
    • Yi-Cheng KuoYu-Chun HsiaoChong HuangJia-He ChengCheng-Wen QueQuan LiLiu-Yang Yang
    • Yi-Cheng KuoYu-Chun HsiaoChong HuangJia-He ChengCheng-Wen QueQuan LiLiu-Yang Yang
    • G02F1/1333H05K5/02H05K7/20
    • H05K5/02G02F2001/133314G02F2001/133328H05K7/20963
    • The present invention provides a flat panel display device, which includes a backlight system and a display panel. The backlight system includes a light source, a light homogenization mechanism, and a back frame. The back frame carries the light source and the light homogenization mechanism, and the light homogenization mechanism guides light from the light source into the display panel. The back frame includes primary assembling pieces, secondary assembling pieces, and a bracing piece for fixing a circuit board. The primary assembling pieces are connected through joining and use different thermally conductive materials. Further, a circuit board is mountable and position adjustable through a bracing piece. The present invention also provides a stereoscopic display device and a plasma display device. The back frame and the backlight system of the present invention have a back frame of simple structure, reduce the expenditure of a back frame mold, facilitate heat dissipation, facility fixing of circuit board, and save the material used for back frame so as to lower down the cost of flat panel display device.
    • 本发明提供一种平板显示装置,其包括背光系统和显示面板。 背光系统包括光源,光匀化机构和后框架。 后框架承载光源和光均化机构,光均化机构将来自光源的光引导到显示面板。 后框架包括主要组装件,辅助组装件和用于固定电路板的支撑件。 主要组装件通过接合连接并使用不同的导热材料。 此外,电路板可安装并且通过支撑件可调节位置。 本发明还提供一种立体显示装置和等离子体显示装置。 本发明的后框架和背光系统具有结构简单的后框架,减少了后框架模具的花费,便于散热,电路板的设备固定,并且节省了用于后框架的材料以便降低 降低平板显示设备的成本。
    • 9. 发明授权
    • Back frame and backlight system
    • 背框和背光系统
    • US08896780B2
    • 2014-11-25
    • US13381917
    • 2011-11-24
    • Yi-Cheng KuoYu-Chun HsiaoChong HuangJia-He ChengCheng-Wen QueQuan LiLiu-Yang Yang
    • Yi-Cheng KuoYu-Chun HsiaoChong HuangJia-He ChengCheng-Wen QueQuan LiLiu-Yang Yang
    • G02F1/1333H05K5/02H05K7/14
    • H05K5/02H05K7/142
    • The present invention provides a back frame of flat panel display device, which includes primary assembling pieces, secondary assembling pieces, and a bracing piece for fixing a circuit board. The primary assembling pieces have a number of at least two. At least one of the primary assembling pieces has an end forming joint sections. The secondary assembling pieces are joined to the primary assembling pieces. The at least two primary assembling pieces are joined through corresponding joint sections thereof. At least one of the primary assembling pieces includes a reinforcement structure formed on the joint section thereof. The bracing piece includes a bracing body, a first suspension section, a first bearing section, and a first resilient bent section. The present invention also provides a backlight system. The back frame and the backlight system of the present invention have a simple structure, reduce the expenditure of a back frame mold, and save the material used for back frame so as to lower down the cost of flat panel display device.
    • 本发明提供一种平板显示装置的后框架,其包括一次装配件,二次装配件和用于固定电路板的支撑件。 主要装配件至少有两个。 主要组装件中的至少一个具有端部形成接头部分。 二次组装件连接到主组装件。 至少两个主要组装件通过其相应的接合部分连接。 主要组装件中的至少一个包括形成在其接合部分上的加强结构。 支撑件包括支撑体,第一悬挂部分,第一支承部分和第一弹性弯曲部分。 本发明还提供一种背光系统。 本发明的后框架和背光系统具有简单的结构,减少了背框模具的消耗,节省了用于背框的材料,从而降低了平板显示装置的成本。