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1. 发明授权

US5798265A Pseudorabies virus (PRV) polynucleotides and their use for preparing virus-resistant eukaryotic cells 失效
标题翻译：伪狂犬病病毒（PRV）多核苷酸及其用于制备病毒抗性真核细胞的用途
公开(公告)号：US5798265A
公开(公告)日：1998-08-25
申请号：US343281
申请日：1994-11-22
申请人： Wolfgang Springer , Jorg Baumgarten , Axel Kretschmer , Heinz Kolbl , Antonius Lobberding , Walter Strube , Peter Thein
发明人： Wolfgang Springer , Jorg Baumgarten , Axel Kretschmer , Heinz Kolbl , Antonius Lobberding , Walter Strube , Peter Thein
IPC分类号： A01K67/027 , A61K31/70 , A61K38/00 , A61K48/00 , A61P31/12 , C07K14/03 , C12N5/00 , C12N7/06 , C12N15/00 , C12N15/113 , C12N15/38 , C12N15/85 , C12N5/10 , C07H21/02 , C07H21/04 , C12N15/86
CPC分类号： C12N15/1133 , C07K14/005 , C12N15/8509 , A01K2217/05 , A01K2227/108 , A01K2267/02 , A61K38/00 , C12N2710/16722
摘要： The invention relates to polynucleotides which contain pseudorabies virus sequences, in particular sequences from the gII region of PRV, in the antisense orientation, their preparation and their use.
摘要翻译：本发明涉及以反义方向含有伪狂犬病病毒序列，特别是来自PRV的gII区的序列及其制备及其用途的多核苷酸。

2. 发明授权

US5061790A Oxidative denaturation of protein analytes 失效
标题翻译：蛋白质分析仪的氧化脱色
公开(公告)号：US5061790A
公开(公告)日：1991-10-29
申请号：US377680
申请日：1989-07-10
申请人： James J. Elting , Heinz Kolbl
发明人： James J. Elting , Heinz Kolbl
IPC分类号： G01N33/531 , A61K39/395 , C07K1/00 , C07K1/113 , C07K14/76 , C07K16/00 , G01N33/53 , G01N33/574 , G01N33/68
CPC分类号： G01N33/57473 , G01N33/5306 , G01N33/6803
摘要： A method for conferring or increasing the antigenicity of a disulfide-crosslinked protein by treating the protein with an oxidizing agent, such as periodate, having an oxidation potential sufficient to cleave disulfide linkages. Excess oxidizing agent is then inactivated by addition of a reducing agent. The resulting protein exhibits an increase in its ability to be bound by select antibodies, particularly monoclonal antibodies directed to linear peptide epitopes in the protein.

3. 发明授权

US4218032A Apparatus for convoluting webs onto rotary cores 失效
标题翻译：用于将卷筒卷绕到旋转芯上的装置
公开(公告)号：US4218032A
公开(公告)日：1980-08-19
申请号：US13623
申请日：1979-02-21
申请人： Erich Nagel , Wolfgang Zahn , Heinz Kolbl , Horst Wildner , Ernst Ismann , Siegfried Bartel , Ernst Biedermann , Karl Dreher
发明人： Erich Nagel , Wolfgang Zahn , Heinz Kolbl , Horst Wildner , Ernst Ismann , Siegfried Bartel , Ernst Biedermann , Karl Dreher
IPC分类号： G03C3/00 , B65H19/28 , G03B1/56 , G03B17/26 , G03B27/58 , G03B1/04 , B65H75/28
CPC分类号： G03B27/588 , G03B1/56 , G03B17/26
摘要： Apparatus for convoluting a web of photographic material onto a rotary core in a lighttight cassette has an elongated channel which is pivotably mounted in the cassette and whose outlet is normally tangential to the peripheral surface of the core. The outlet of the channel is detachably or permanently connected with a flexible or deformable strip-shaped element in the form of a link chain, plastic band, textile band or metallic band which surrounds a substantial part of or the entire peripheral surface of the core. When the leader of a web is introduced into and advanced beyond the outlet of the channel while the core rotates in a direction to convolute the web, the foremost part of the leader penetrates between the core and the flexible element and adheres to the peripheral surface of the core not later than upon the making of approximately two convolutions. During winding, the flexible element insures that the neighboring convolutions of the web on the core are tightly packed against each other. When the web is being withdrawn, the flexible element brakes the web and prevents clockspringing of convoluted material.
摘要翻译：用于将照相材料卷卷绕到光密封盒中的旋转芯上的装置具有细长的通道，其可枢转地安装在盒中，并且其出口通常与芯的外围表面相切。通道的出口可拆卸地或永久地连接有环形链条，塑料带，纺织带或金属带形式的柔性或可变形的带状元件，该带状元件环绕芯的大部分或整个外围表面。当纤维的引导件被引入并超出通道的出口时，其中芯沿着卷绕卷筒纸的方向旋转时，引导件的最前部分穿过芯部和柔性元件之间并附着到核心不迟于大约两次卷积的制作。在卷绕期间，柔性元件确保在芯上的纤维网的相邻卷圈彼此紧密地包装。当纤维网被取出时，柔性元件制动纤网并防止卷曲材料的时钟弹簧。

4. 发明授权

US4208120A Apparatus for winding portions of films onto takeup reels which are confined in cassettes or the like 失效
标题翻译：用于将薄膜的部分卷绕到收卷盘上的装置，卷取卷筒被限制在盒子等中
公开(公告)号：US4208120A
公开(公告)日：1980-06-17
申请号：US845885
申请日：1977-10-27
申请人： Alois Zachmeier , Horst Wildner , Heinz Kolbl
发明人： Alois Zachmeier , Horst Wildner , Heinz Kolbl
IPC分类号： G03B17/00 , G03D13/00 , G03B1/18
CPC分类号： G03D13/001
摘要： Apparatus for winding the remaining unexposed frames of partly exposed films onto takeup reels in film cassettes has a socket for reception of a portion of a cassette and one or more sealing strips or cushions which prevent entry of light through the exposure window of the cassette. The gear of the takeup reel is automatically engaged by a driving gear which completes the winding of film onto the takeup reel with a force which cannot overcome the resistance of connection between the trailing end of the film and the cassette. The driving gear receives torque from a motor which is started by a microswitch in response to proper insertion of a cassette into the socket.
摘要翻译：用于将剩余的未曝光的部分曝光的胶片的框架卷绕在胶卷盒中的卷取卷轴上的装置具有用于接收盒的一部分的插座和一个或多个防止光通过盒的曝光窗口进入的密封条或垫子的插座。卷取卷轴的齿轮通过驱动齿轮自动啮合，该驱动齿轮以不能克服胶片尾端与盒之间的连接阻力的力完成胶卷卷绕到收卷卷轴上。驱动齿轮响应于将卡盒正确插入插座而从微型开关启动的马达接收扭矩。

5. 发明授权

US5030697A Polymer-bound dyes, process for their production and use 失效
标题翻译：聚合物结合染料，其生产和使用过程
公开(公告)号：US5030697A
公开(公告)日：1991-07-09
申请号：US408858
申请日：1989-09-18
申请人： Herbert Hugl , Bruno Bomer , Heinz Kolbl , Florin Seng , Eberhard Kuckert , Gunter Sackmann
发明人： Herbert Hugl , Bruno Bomer , Heinz Kolbl , Florin Seng , Eberhard Kuckert , Gunter Sackmann
IPC分类号： C09B69/10 , G01N33/532
CPC分类号： C09B69/10 , G01N33/532
摘要： A polymer-bound linkable dye comprisinga) a water-soluble polymer backbone,b) a dye covalently bound thereto, andc) functional groups which enable the polymer-dye to link covalently with biological materials,in which the water-soluble polymer backbone is a copolymer which contains arcylamide, methacrylamide, N-C.sub.1 -C.sub.4 alkyl(meth)acrylamide, N,N-C.sub.1 -C.sub.4 dialkylacrylamide, N-vinylpyrrolidone, N-vinylpiperidone, N-vinylcaprolactam, N-vinylformamide, N-vinylacetamide, N-vinyl-N-methylacetamide, N-vinyl-O-methylurethane, ethene or vinylmethylether as nonionic monomer blocks. The polymer-bound dye can be linked to a biologically active material such as an antibody or nucleic acid and used analytically.
摘要翻译：一种聚合物键合的可连接染料，其包含a）水溶性聚合物主链，b）与其共价结合的染料，和c）能使聚合物染料与生物材料共价连接的官能团，其中水溶性聚合物骨架是含有甲酰胺，甲基丙烯酰胺，（甲基）丙烯酰胺，N，N-C 1 -C 4二烷基丙烯酰胺，N-乙烯基吡咯烷酮，N-乙烯基哌啶酮，N-乙烯基己内酰胺，N-乙烯基甲酰胺，N-乙烯基乙酰胺，N-乙烯基 N-甲基乙酰胺，N-乙烯基-O-甲基氨基甲酸酯，乙烯或乙烯基甲基醚作为非离子单体嵌段。聚合物结合的染料可以连接到生物活性物质如抗体或核酸上，并用于分析。

6. 发明授权

US4647581A Bicyclic pesticidal agents 失效
标题翻译：双环杀虫剂
公开(公告)号：US4647581A
公开(公告)日：1987-03-03
申请号：US588851
申请日：1984-03-12
申请人： Heinz Kolbl , Rudolf Gompper , Wolfgang Behrenz , Ingeborg Hammann , Bernhard Homeyer , Gunther Hermann
发明人： Heinz Kolbl , Rudolf Gompper , Wolfgang Behrenz , Ingeborg Hammann , Bernhard Homeyer , Gunther Hermann
IPC分类号： A01N33/18 , A01N27/00 , A01N29/00 , A01N29/04 , A01N29/08 , A01N31/06 , A01N35/06 , A01N35/10 , A01N37/00 , A01N37/08 , A01N37/18 , A01N37/34 , A01N37/36 , A01N37/42 , A01N37/48 , A01N37/50 , A01N41/10 , A01N43/20 , A01N45/00 , A01N45/02 , A01N55/00 , C07C255/45 , C07D303/46
CPC分类号： C07C255/00 , A01N37/34 , A01N37/36 , A01N43/20 , C07D303/46
摘要： Combating pests with compounds of the formula ##STR1## in which the radicals can have many specifically recited definitions. Many of the compounds are novel, particularly those where R' is --CN and R.sup.2 is --CN or --CONH.sub.2.
摘要翻译：将害虫与式（IMAGE）化合物相结合，其中基团可以具有许多具体叙述的定义。许多化合物是新的，特别是其中R'是-CN且R 2是-CN或-CONH 2的化合物。

7. 发明授权

US4985364A Preparation of cyclopropanecarboxylic acids 失效
标题翻译：制备环丙烷羧酸
公开(公告)号：US4985364A
公开(公告)日：1991-01-15
申请号：US731234
申请日：1985-05-06
申请人： Heinz Hildebrand , Werner Zitzmann , Dieter Arlt , Heinz Kolbl
发明人： Heinz Hildebrand , Werner Zitzmann , Dieter Arlt , Heinz Kolbl
IPC分类号： C12N1/14 , C12P7/40 , C12P41/00 , C12R1/38 , C12R1/645 , C12R1/70
CPC分类号： C12R1/66 , C12P41/005 , C12P7/40 , C12R1/79 , Y10S435/919 , Y10S435/932
摘要： A process for the preparation of a (.+-.)-trans-cyclopropanecarboxylic acid salt thereof of the formula ##STR1## in which R is halogen or C.sub.1 -C.sub.4 -alkyl, andR.sup.1 is hydrogen or the equivalent of a metal ion,which comprises contacting a (.+-.)-trans-cyclo-propane-carboxylic ester of the formula ##STR2## in which R.sup.2 is methyl or ethyl,with a hydrolase which is of microbial origin and isolating the resulting (.+-.)-trans-cyclopropanecarboxylic acid.
摘要翻译：制备式（IMA）的（+/-） - 反式环丙烷羧酸盐的方法，其中R是卤素或C 1 -C 4烷基，R 1是氢或等价于金属离子，其中包括使其中R2是甲基或乙基的式（IMA）的（+/-） - 反 - 环 - 丙烷 - 羧酸酯与微生物来源的水解酶接触并分离所得（+/-） - 反式 - 环丙烷羧酸。

8. 发明授权

US4195541A Apparatus for perforating webs of photosensitive material in copying machines or the like 失效
标题翻译：用于在复印机等中对感光材料的纤网进行穿孔的装置
公开(公告)号：US4195541A
公开(公告)日：1980-04-01
申请号：US912057
申请日：1978-06-02
申请人： Horst Wildner , Heinz Kolbl , Alois Zachmeier
发明人： Horst Wildner , Heinz Kolbl , Alois Zachmeier
IPC分类号： B26D5/08 , B26F1/02
CPC分类号： B26D5/086 , B26D5/08 , B26F1/02 , Y10T83/8768 , Y10T83/8785 , Y10T83/8853 , Y10T83/8881
摘要： Apparatus for making holes in a web of photosensitive material which is transported in a copying machine has an electromagnet with a reciprocable armature connected to one leg of a U-shaped carrier. The other leg of the carrier supports a material removing tool which penetrates through the web when the electromagnet is energized. The carrier is held against wobbling by a ball bearing which is connected to its one leg and extends with minimal clearance between two parallel guide faces which are machined into a stationary holder for the electromagnet. The holder has a plate-like extension with a hole which receives the tip of the tool subsequent to penetration of such tip through the web. The tool is normally located at one side of the plane of the web, and the extension is located at the other side of such plane. The clearance between the bearing and the guide faces is less than that clearance which would permit such lateral movement of the tool that the latter would fail to penetrate into the hole of the extension in response to energization of the electromagnet.
摘要翻译：用于在复印机中传送的感光材料卷材上的孔的设备具有电磁铁，其具有连接到U形载体的一个支腿的往复电枢。载体的另一支腿支撑当电磁铁通电时穿过网状物的材料去除工具。承载件通过滚珠轴承保持抵抗摆动，该滚珠轴承连接到其一个支腿并以两个平行的引导面之间的最小间隙延伸，该平行的引导面被加工成用于电磁体的固定保持架。保持器具有带有孔的板状延伸部，该孔在该尖端穿过腹板后接收工具的尖端。工具通常位于纸幅平面的一侧，延伸部位于该平面的另一侧。轴承和导向面之间的间隙小于允许工具的这种侧向运动的间隙，后者将不能够响应于电磁体的通电而渗透到延伸部的孔中。

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