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1. 发明申请

US20110165700A1 CLASSES OF COMPOUNDS THAT INTERACT WITH INTEGRINS 审中-公开
标题翻译：与INTEGRINS相互影响的化合物类别
公开(公告)号：US20110165700A1
公开(公告)日：2011-07-07
申请号：US13047601
申请日：2011-03-14
申请人： Wim MEUTERMANS , Michael L. West , Giang Thanh Le , Judy Halliday , Christopher Clark
发明人： Wim MEUTERMANS , Michael L. West , Giang Thanh Le , Judy Halliday , Christopher Clark
IPC分类号： G01N33/566
CPC分类号： A61K31/351 , A61K31/70
摘要： A method of inhibiting or effecting the activity of an integrin receptor comprises contacting an integrin with a pyranose of formula I, or a pharmaceutically acceptable salt thereof.
摘要翻译：抑制或影响整联蛋白受体活性的方法包括使整联蛋白与式I的吡喃糖或其药学上可接受的盐接触。

2. 发明申请

US20080176936A1 Classes of Compounds that Interact with Integrins 审中-公开
标题翻译：与整合素相互作用的化合物类
公开(公告)号：US20080176936A1
公开(公告)日：2008-07-24
申请号：US11813737
申请日：2006-02-02
申请人： Wim Meutermans , Michael L. West , Giang Thanh Le , Judy Halliday , Christopher Clark
发明人： Wim Meutermans , Michael L. West , Giang Thanh Le , Judy Halliday , Christopher Clark
IPC分类号： A61K31/351 , C07D315/00 , A61P3/10
CPC分类号： A61K31/351 , A61K31/70
摘要： A method of inhibiting or effecting the activity of an integral receptor which comprises contacting an integrin with a compound of formula I, or a pharmaceutically acceptable salt thereof; General Formula I Wherein the ring may be of any configuration; Z is sulphur, oxygen, CH2, NH, NRA or hydrogen, in the case where Z is hydrogen then R1 is not present, RA is selected from the set defined for R1 to R5, X is oxygen or NRA providing that at least one X of General Formula I is NRA, X may also combine independently with one of R1 to R5 to form an azide, R1 to R5 are independently selected from the group comprising H, —(CO)R6 or an alkyl, acyl, alkenyl, alkynyl, heteroalkyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl substituent of 1 to 20 atoms, which is optionally substituted, and can be branched or linear wherein substituents may optionally be further substituted, wherein R6 is selected from the group comprising an alkyl, acyl, alkenyl, alkynyl, heteroalkyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl substituent of 1 to 20 atoms, which is optionally substituted, and can be branched or linear wherein substituents may optionally be further substituted, with the proviso that XR2 or XR3 or XR4 or XR5 is not NH2, with the further proviso that not more than one of R2 to R5 is hydrogen, where the group X is NRA and RA is not hydrogen, the groups RA and the corresponding group R2 to R5 may combine to form a cycle.
摘要翻译：一种抑制或影响整体受体活性的方法，其包括使整联蛋白与式I化合物或其药学上可接受的盐接触; 通式I其中环可以是任何配置; 在Z是氢的情况下，Z是硫，氧，CH 2，NH，NR A或氢，则不存在R 1 R A选自从R 1至R 5定义的集合，X是氧或NR A，条件是通式I的至少一个X是NR A，X也可以独立地与R 1至R 5中的一个结合形成叠氮化物，R 1至R 5独立地选自H， - （CO）R 6或烷基，酰基，烯基，炔基，杂烷基，芳基，杂芳基，芳基烷基或杂芳基烷基取代基 1至20个原子，其任选被取代，并且可以是支链或直链的，其中取代基可任选被进一步取代，其中R 6选自烷基，酰基，烯基，炔基， 1至20个原子的杂烷基，芳基，杂芳基，芳基烷基或杂芳基烷基取代基，其任选被取代，并且可以是支链或直链的取代基可以任选地被进一步取代，条件是XR 2或XR 3或XR 4或XR 5 不是NH 2，另外条件是R 2至R 5中不超过一个是氢，其中基团X是NR A和R O， A 不是氢，基团R A和相应的基团R 2至R 5可以结合形成一个循环。

3. 发明申请

US20170050761A1 MULTI-CLEAT INDUSTRIAL BIN 审中-公开
标题翻译：多功能工业用品
公开(公告)号：US20170050761A1
公开(公告)日：2017-02-23
申请号：US14308544
申请日：2014-06-18
申请人： Christopher Clark , Gerald A. Sciarini , Travis D. Shamp
发明人： Christopher Clark , Gerald A. Sciarini , Travis D. Shamp
IPC分类号： B65D21/02 , B65D1/42
CPC分类号： B65D25/22
摘要： The multiple cleat bin of the present invention includes a base, a front wall, two opposing sidewalls, and a substantially vertical rear wall having an upper rim. The rear wall includes a cleat near the upper rim of the rear wall and a second cleat formed at the base of the rear wall. A third cleat formed in the rear wall may also be included. A fourth cleat formed in the rear wall may also be included. Preferably, a forewall and kick out wall are included to form a stacking space such that a second may be placed within bin for increased packing density for shipping or storage. The additional cleats provide additional strength for bins manufactured of more economical or recycled polymers that tend to be softer or less rigid. The use of multiple cleats allows for improved strength and flexibility in use. The bin may also include multi-element structural trusses at the front wall, right sidewall, rear wall and left sidewall are integrally formed such that they form a single structural element that encircles the upper edge of bin.
摘要翻译：本发明的多个防滑钉仓包括底座，前壁，两个相对的侧壁以及具有上边缘的大致垂直的后壁。后壁在后壁的上边缘附近包括防滑板，并且在后壁的基部处形成第二防滑板。还可以包括形成在后壁中的第三防滑板。还可以包括形成在后壁中的第四防滑板。优选地，包括前壁和踢出壁以形成堆叠空间，使得第二可以放置在箱内以增加运输或储存的包装密度。额外的防滑板为由更经济或再循环的聚合物制造的箱体提供额外的强度，其倾向于较软或较不刚性。使用多个夹板可以提高使用中的强度和灵活性。垃圾箱还可以包括在前壁，右侧壁，后壁和左侧壁上的多元件结构桁架整体形成，使得它们形成围绕仓的上边缘的单个结构元件。

4. 发明授权

US07646407B2 Digital exposure circuit for an image sensor 失效
标题翻译：用于图像传感器的数字曝光电路
公开(公告)号：US07646407B2
公开(公告)日：2010-01-12
申请号：US11121956
申请日：2005-05-05
申请人： Eric R. Fossum , Alexander I. Krymski , Roger A. Panicacci , Christopher Clark
发明人： Eric R. Fossum , Alexander I. Krymski , Roger A. Panicacci , Christopher Clark
IPC分类号： H04N5/235 , H04N3/14
CPC分类号： H04N5/2352 , H04N5/2351
摘要： Automatic exposure adjusting device considers the image on a pixel-by-pixel basis. Each pixel is characterized according to its most significant bits. After the pixels are characterized, the number of pixels in any particular group is counted. That counting is compared with thresholds which set whether the image is over exposed, under exposed, and can optionally also determine if the image is seriously over exposed or seriously under exposed. Adjustment of the exposure is carried out to bring the image to a more desired state.
摘要翻译：自动曝光调整装置以像素为单位考虑图像。每个像素根据其最高有效位进行表征。在对像素进行表征之后，对任何特定组中的像素数进行计数。将该计数与设置图像是否暴露在曝光下的阈值进行比较，并且还可以可选地确定图像是否严重暴露或严重暴露在外。进行曝光调整，使图像变得更理想。

5. 发明申请

US20070089157A1 Television advertising number system 审中-公开
标题翻译：电视广告号码系统
公开(公告)号：US20070089157A1
公开(公告)日：2007-04-19
申请号：US11328948
申请日：2006-01-10
申请人： Christopher Clark
发明人： Christopher Clark
IPC分类号： H04N7/173 , G06F3/00 , G06F13/00 , H04N7/16 , H04N5/445
CPC分类号： H04L12/2803 , H04L12/2838 , H04L2012/2849 , H04N5/445 , H04N21/235 , H04N21/4122 , H04N21/4143 , H04N21/42653 , H04N21/435 , H04N21/436 , H04N21/43637 , H04N21/440218 , H04N21/47214 , H04N21/4725 , H04N21/47815 , H04N21/4782 , H04N21/812 , H04N21/8153 , H04N21/8586 , H04W84/02
摘要： Supplemental program information is provided to a television in conjunction with a television program, where the supplemental program information is related to the subject matter of the television program. The supplemental program information and an access number are embedded in a digital video data stream of the television program. The digital video data stream is transmitted and received, and the access number is extracted from the received data stream. Based on the extracted access number, a determination is made whether the supplemental program information will be provided to the television. The television program may be an advertisement, and the supplemental program information may be advertising information related to the subject matter of the advertisement. For example, the supplemental program information may be a URL pointing to a web page that describes features of an advertiser's product. Once activated by a valid access number, a graphic image is inserted into the advertisement indicating that further product information is available on the web page.
摘要翻译：辅助节目信息与电视节目一起提供给电视节目，其中补充节目信息与电视节目的主题有关。补充节目信息和接入号码嵌入在电视节目的数字视频数据流中。发送和接收数字视频数据流，并从接收到的数据流中提取接入号码。基于提取的访问号码，确定是否将补充节目信息提供给电视机。电视节目可以是广告，并且补充节目信息可以是与广告的主题相关的广告信息。例如，补充程序信息可以是指向描述广告商产品的特征的网页的URL。一旦通过有效的访问号码激活，图形图像被插入到广告中，指示在网页上有更多的商品信息可用。

6. 发明授权

US07093224B2 Model-based logic design 有权
公开(公告)号：US07093224B2
公开(公告)日：2006-08-15
申请号：US09941158
申请日：2001-08-28
申请人： William R. Wheeler , Matthew J. Adiletta , Christopher Clark , Timothy J. Fennel
发明人： William R. Wheeler , Matthew J. Adiletta , Christopher Clark , Timothy J. Fennel
IPC分类号： G06F17/50
CPC分类号： G06F17/5045 , G06F17/5022
摘要： A technique for designing a logic circuit includes specifying a model. The model including combinatorial blocks, state elements and graphical library elements. The technique maintains a data structure representative of the model, and generates an architectural model and an implementation model from the data structure. The data structure represents a descriptive net list of the model. The architectural model includes C++ code and the implementation model includes Verilog.

7. 发明申请

US20060107160A1 Method and apparatus for optimized parallel testing and access of electronic circuits 失效
公开(公告)号：US20060107160A1
公开(公告)日：2006-05-18
申请号：US11286915
申请日：2005-11-23
申请人： Michael Ricchetti , Christopher Clark
发明人： Michael Ricchetti , Christopher Clark
IPC分类号： G01R31/28 , G06F11/00
CPC分类号： G01R31/318563 , G01R31/318516 , G01R31/318555 , G11C29/56 , G11C2029/2602
摘要： A Parallel Test Architecture (PTA) is provided that facilitates concurrent test, debug or programmable configuration of multiple electronic circuits (i.e., simultaneously). The PTA includes a communications path, a primary test controller, and a number of local test controllers. The primary controller provides stimulus, expected, and mask data to the local controllers over the communications path. The local controllers apply the stimulus data to the electronic circuits, receive resultant data generated by the circuits in response to the stimulus data, and locally verify the resultant data against the expected data substantially concurrently. When the communications path is implemented as an IEEE 1149.1 (JTAG) test bus, the primary controller can provide the expected and mask data to the local controllers over the TDO and TRSTN lines while the TAP controllers of the electronic circuits are in the Shift-IR or Shift-DR state to enable concurrent testing over a traditional five wire multi-drop IEEE 1149.1 test bus.

8. 发明申请

US20110054515A1 Device and method for occluding the left atrial appendage 审中-公开
标题翻译：用于闭塞左心耳的装置和方法
公开(公告)号：US20110054515A1
公开(公告)日：2011-03-03
申请号：US12583744
申请日：2009-08-25
申请人： John Bridgeman , Gregg Sutton , Christopher Clark
发明人： John Bridgeman , Gregg Sutton , Christopher Clark
IPC分类号： A61M29/02
CPC分类号： A61B17/12122 , A61B17/0057 , A61B17/12172 , A61B2017/00601 , A61B2017/00632
摘要： An implantable medical device for insertion in the left atrial appendage includes a cap coupled to a frame. The cap constrains movement of the legs of the frame during collapse and expansion of the device, such that the device can be deployed, recalled and redeployed without the device being damaged or the legs of the frame getting tangled.
摘要翻译：用于插入左心耳中的可植入医疗装置包括联接到框架的盖。盖子在装置的折叠和膨胀期间限制框架的腿的运动，使得可以部署，召回和重新部署装置，而不会损坏装置或框架的腿变得纠结。

9. 发明申请

US20050060622A1 System and method for optimized test and configuration throughput of electronic circuits 失效
标题翻译：电子电路优化测试和配置吞吐量的系统和方法
公开(公告)号：US20050060622A1
公开(公告)日：2005-03-17
申请号：US10896646
申请日：2004-07-22
申请人： Christopher Clark , Michael Ricchetti
发明人： Christopher Clark , Michael Ricchetti
IPC分类号： G01R31/00 , G01R31/28 , G01R31/3185 , G01R31/319 , G06F17/00 , H05K20060101
CPC分类号： G01R31/31926 , G01R31/318533
摘要： A system and method for maximizing the throughput of test and configuration in the manufacture of electronic circuits and systems. The system employs a tester having a flexible parallel test architecture with expandable resources that can accommodate a selected number of units under test (UUTs). The parallel test architecture is configurable to accept separate banks or partitions of UUTs, thereby enabling the system to obtain an optimal or maximum achievable throughput of test and configuration for the UUTs. The system determines an optimal or maximum achievable throughput by calculating a desired number N of UUTs to be tested/configured in parallel. Testing or configuring this desired number of UUTs in parallel allows the handling time to be balanced with the test and configuration times, thereby resulting in the maximum achievable throughput.
摘要翻译：一种用于在电子电路和系统的制造中最大化测试和配置的吞吐量的系统和方法。该系统采用具有可扩展资源的灵活并行测试架构的测试仪，可扩展资源可容纳选定数量的被测单元（UUT）。并行测试体系结构可配置为接受UUT的独立库或分区，从而使系统能够获得UUT测试和配置的最佳或最大可实现吞吐量。系统通过计算要并联测试/配置的UUT的期望数量N来确定最佳或最大可实现吞吐量。并行测试或配置所需数量的UUT可以使处理时间与测试和配置时间相平衡，从而达到最大可实现的吞吐量。

10. 发明申请

US20160229588A1 SUPPORT CLIPS FOR INDUSTRIAL BINS 审中-公开
标题翻译：工业用品支持服务
公开(公告)号：US20160229588A1
公开(公告)日：2016-08-11
申请号：US14616604
申请日：2015-02-06
申请人： Christopher Clark , Gerald A. Sciarini , Travis D. Shamp
发明人： Christopher Clark , Gerald A. Sciarini , Travis D. Shamp
IPC分类号： B65D25/22 , F16M13/02
CPC分类号： F16M13/02 , B25H3/04
摘要： The support clip for industrial bins includes at least one support on the clip and can be used to increase the hanging load of an industrial bin when hung. The supports may be in the form of ledges or cleats. The multi-support clip provides additional hanging strength for existing bins or allows flexibility to use bins manufactured of more economical or recycled polymers that tend to be softer or less rigid. The additional supports on the clip may also allow the bin to be hung in a sloped forward configuration. The use of multi-support clips allow for improved bin strength when hung and flexibility for placement and use of bins already in service. The support clip is manufactured by a process of metal extrusion, metal stamping, or metal die casting or polymer extrusion, thermoforming, injection molding, blow molding, and rotocasting.
摘要翻译：用于工业箱的支撑夹包括夹子上的至少一个支撑件，并且可以用于当悬挂时增加工业箱的悬挂载荷。支撑件可以是凸缘或夹板的形式。多支撑夹可为现有料仓提供额外的悬挂强度，或允许使用易于更柔软或更不刚性的更经济或回收聚合物制成的料箱的灵活性。夹子上的附加支撑件还可以允许垃圾箱以倾斜的正向配置挂起。使用多支撑夹可以在悬挂和弹性放置和使用已经投入使用的垃圾箱时提高箱体强度。支撑夹是通过金属挤压，金属冲压或金属压铸或聚合物挤出，热成型，注射成型，吹塑和旋转加工的方法制造的。

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