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1. 发明申请

US20100160862A1 VARIABLE STIFFNESS INTRODUCER SHEATH WITH TRANSITION ZONE 审中-公开
标题翻译：可变刚度介绍带过渡区的风
公开(公告)号：US20100160862A1
公开(公告)日：2010-06-24
申请号：US12341459
申请日：2008-12-22
申请人： William L. Howat , Thomas A. Osborne
发明人： William L. Howat , Thomas A. Osborne
IPC分类号： A61M5/00 , B32B37/06
CPC分类号： A61M25/0054 , A61M25/0012 , A61M25/005 , A61M25/0053 , A61M2025/0047
摘要： An introducer sheath includes a lubricious inner liner having a passageway extending longitudinally therethrough, a reinforcing member positioned over the inner liner, and an outer jacket positioned longitudinally over the reinforcing member and the inner liner. The outer jacket has a higher durometer proximal portion, a lower durometer distal portion, and a transition zone between the proximal portion and the distal portion. The transition zone has a variable durometer from a junction with the outer jacket proximal portion to a junction with the outer jacket distal portion, to provide a transition between the higher durometer proximal portion and the lower durometer distal portion.
摘要翻译：引导器护套包括具有纵向穿过其延伸的通道的光滑内衬，位于内衬上的加强构件和位于加强构件和内衬之间纵向延伸的外护套。外护套具有较高的硬度近端部分，较低的硬度计远端部分和近端部分与远端部分之间的过渡区域。过渡区具有从与外护套近端部分到外护套远端部分的连接处的可变硬度计，以提供较高硬度计近端部分和下部硬度计远端部分之间的过渡。

2. 发明授权

US08475431B2 Introducer sheath having a braided member and methods of manufacture 有权
标题翻译：具有编织构件的引导器护套和制造方法
公开(公告)号：US08475431B2
公开(公告)日：2013-07-02
申请号：US12176020
申请日：2008-07-18
申请人： William L. Howat
发明人： William L. Howat
IPC分类号： A61M25/00
CPC分类号： A61M25/0012 , A61M25/005 , B29C43/18 , B29C61/006 , B29C2043/3665 , B29K2027/18 , B29K2105/0827 , B29K2105/258 , B29L2023/00 , B29L2031/7542 , Y10T29/49888 , Y10T29/49906
摘要： The present embodiments provide an introducer sheath having a braided member and methods of manufacture. The introducer sheath comprises an inner tube, a braided member disposed over at least a portion of the inner tube, and an outer tube disposed over the inner tube and the braided member. In one embodiment, the braided member comprises a plurality of intersecting first and second wire segments at least partially covered with a coating. At least a portion of the first and second wire segments are bonded together at one or more intersections, for example, by melting the coating, to reduce movement of at least one of the first and second wire segments with respect to one another. Optionally, a coiled member having a plurality of turns may be disposed over a portion of the braided member and the inner tube.
摘要翻译：本实施例提供具有编织构件的导引器护套和制造方法。引导器鞘包括内管，设置在内管的至少一部分上的编织构件，以及设置在内管和编织构件上的外管。在一个实施例中，编织构件包括至少部分地覆盖有涂层的多个相交的第一和第二线段。第一和第二线段的至少一部分在一个或多个交点处结合在一起，例如通过熔化涂层，以减少第一和第二线段中的至少一个相对于彼此的运动。可选地，可以在编织构件和内管的一部分上设置具有多个匝的螺旋构件。

3. 发明授权

US07575591B2 Prosthesis graft with Z pleating 有权
标题翻译：假体移植与Z打褶
公开(公告)号：US07575591B2
公开(公告)日：2009-08-18
申请号：US10725147
申请日：2003-12-01
申请人： William L. Howat , Tara Schaneville
发明人： William L. Howat , Tara Schaneville
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/844 , A61F2/88 , A61F2/89 , A61F2/90 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2220/0075
摘要： A prosthesis configured for establishing a fluid flow path through an artery or the like includes a generally cylindrical body portion formed from graft material. In accordance with a preferred aspect of the device, at least a portion of the graft material is profiled where the profile defines a geometric pattern, e.g. a series of Z pleats.
摘要翻译：构造成用于建立通过动脉或类似物的流体流动路径的假体包括由移植材料形成的大致圆柱形的主体部分。根据装置的优选方面，移植材料的至少一部分被成型，其中轮廓限定几何图案，例如，一系列Z褶。

4. 发明授权

US07815762B2 Method of forming an introducer sheath 有权
标题翻译：形成导引鞘的方法
公开(公告)号：US07815762B2
公开(公告)日：2010-10-19
申请号：US12198500
申请日：2008-08-26
申请人： David Christian Lentz , William L. Howat
发明人： David Christian Lentz , William L. Howat
IPC分类号： B29C65/00 , B29C49/00 , B32B37/00 , B65C3/16 , C08J5/00 , A61M25/00
CPC分类号： A61M25/0012 , A61M25/0026 , A61M25/005 , A61M25/0662 , B29C57/00 , B29C61/025 , B29C65/02 , B29C65/66 , B29C66/1122 , B29C66/545 , B29C66/63 , B29C66/71 , B29C66/73115 , B29C66/73116 , B29C66/7371 , B29C66/73715 , B29C66/7392 , B29C66/964 , B29C70/70 , B29C70/82 , B29D23/001 , B29K2027/18 , B29K2105/0827 , B29L2023/005 , B29L2031/24 , F16L11/081 , Y10T156/1005 , Y10T156/1033 , B29K2077/00 , B29K2075/00
摘要： A method of forming an introducer sheath having a crease-free tapered distal tip portion. A mandrel is provided having an outer configuration comprising an elongated body and a tapered distal tip portion. A generally tubular inner liner comprising heat shrinkable PTFE, is positioned over the mandrel. The inner liner is heat shrunk to the outer configuration of the mandrel, in a manner that avoids the formation of creases along the inner diameter of the liner. A reinforcing member is positioned over a length of the inner liner, and an outer jacket is positioned over the reinforcing member and the inner liner. The liner, reinforcing member, and outer jacket are heated in a heat shrink enclosure, whereby the outer jacket melts and bonds to an outer surface of the inner liner.
摘要翻译：一种形成具有无褶皱锥形远端尖端部分的导引鞘的方法。提供具有包括细长主体和锥形远侧末端部分的外部构造的心轴。包括热收缩PTFE的通常管状的内衬被定位在心轴上方。内衬被热收缩到心轴的外部构造，以避免沿着衬垫的内径形成褶皱的方式。加强构件定位在内衬的长度上，并且外护套位于加强构件和内衬上。衬套，加强构件和外护套在热收缩外壳中被加热，由此外护套熔化并结合到内衬的外表面。

5. 发明授权

US08088156B2 Graft material attachment device and method 有权
标题翻译：接枝材料附着装置及方法
公开(公告)号：US08088156B2
公开(公告)日：2012-01-03
申请号：US10680805
申请日：2003-10-07
申请人： Juan Borges , Clifford J. Dwyer , William L. Howat
发明人： Juan Borges , Clifford J. Dwyer , William L. Howat
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/91 , A61F2002/075 , A61F2002/828 , A61F2002/9522 , A61F2250/0039
摘要： A stent-graft fabricated from a thin-walled, high strength material provides for a more durable and lower profile endoprosthesis. The stent-graft comprises one or more stent segments covered with a fabric formed by the weaving, knitting or braiding of a biocompatible, high tensile strength, abrasion resistant, highly durable yarn such as ultra high molecular weight polyethylene. The one or more stent segments may be balloon expandable or self-expanding. The fabric may be attached to the stent segments utilizing any number of known materials and techniques. The fabric may be attached to the stent segments utilizing an attachment device that secures the fabric to a strut of the stent segment by sandwiching the fabric between itself and the stent strut.
摘要翻译：由薄壁，高强度材料制成的支架移植物提供更耐用和更低轮廓的内置假体。支架移植物包括一个或多个支架段，其覆盖有通过编织，编织或编织生物相容性，高抗拉强度，耐磨损，高耐用性的纱线（例如超高分子量聚乙烯）形成的织物。一个或多个支架段可以是气囊扩张的或自膨胀的。织物可以利用任何数量的已知材料和技术附接到支架段上。织物可以利用附接装置附接到支架段，该附接装置通过将织物夹在其与支架支柱之间来将织物固定到支架段的支柱上。

6. 发明申请

US20080157017A1 VALVE ASSEMBLY 有权
标题翻译：阀组件
公开(公告)号：US20080157017A1
公开(公告)日：2008-07-03
申请号：US11966385
申请日：2007-12-28
申请人： Edwin E. Macatangay , William L. Howat
发明人： Edwin E. Macatangay , William L. Howat
IPC分类号： F16K5/00
CPC分类号： A61M39/0613 , A61B17/3462 , A61M2039/0633 , A61M2039/0673 , A61M2039/0686
摘要： A valve assembly includes a valve collar, a rotatable valve control member, and a flexible valve member disposed therebetween. The valve control member and the valve collar are aligned to define an elongated passageway, and the flexible valve member is disposed along the passageway. The valve collar is structured such that at least a portion thereof is capable of radial flexure upon engagement with a mechanism on the rotatable valve control member. One end of the valve member is secured to the valve collar, and the other end is secured to the rotatable valve control member. Upon rotation of the rotatable valve control member relative to the valve collar, the mechanism of the rotatable valve control member engages the valve collar portion in a manner such that the valve collar portion flexes in a radial direction and a tactile sensation is produced thereby, and the flexible valve member constricts from an open position to a position wherein the flexible valve member opening is at least partially closed to passage of fluid therethrough.
摘要翻译：阀组件包括阀套，可旋转阀控制构件和设置在其间的柔性阀构件。阀控制构件和阀环对准以限定细长通道，并且柔性阀构件沿着通道设置。阀套环被构造成使得其至少一部分能够在与可旋转阀控制构件上的机构接合时具有径向挠曲。阀构件的一端固定在阀套上，另一端固定在可旋转阀控制件上。在可旋转阀控制构件相对于阀套环旋转时，可旋转阀控制构件的机构以这样的方式接合阀环部分，使得阀套部分沿径向方向弯曲并且由此产生触感，并且柔性阀构件从打开位置收缩到其中柔性阀构件开口至少部分地关闭以使流体通过其中的位置。

7. 发明授权

US08002749B2 Valve assembly 有权
标题翻译：阀组件
公开(公告)号：US08002749B2
公开(公告)日：2011-08-23
申请号：US11966385
申请日：2007-12-28
申请人： Edwin E. Macatangay , William L. Howat
发明人： Edwin E. Macatangay , William L. Howat
IPC分类号： A61M5/178 , A61M5/00 , A61M5/14 , A61M25/16 , A61M25/18 , A61M39/00 , A61M39/10
CPC分类号： A61M39/0613 , A61B17/3462 , A61M2039/0633 , A61M2039/0673 , A61M2039/0686
摘要： A valve assembly includes a valve collar, a rotatable valve control member, and a flexible valve member disposed therebetween. The valve control member and the valve collar are aligned to define an elongated passageway, and the flexible valve member is disposed along the passageway. The valve collar is structured such that at least a portion thereof is capable of radial flexure upon engagement with a mechanism on the rotatable valve control member. One end of the valve member is secured to the valve collar, and the other end is secured to the rotatable valve control member. Upon rotation of the rotatable valve control member relative to the valve collar, the mechanism of the rotatable valve control member engages the valve collar portion in a manner such that the valve collar portion flexes in a radial direction and a tactile sensation is produced thereby, and the flexible valve member constricts from an open position to a position wherein the flexible valve member opening is at least partially closed to passage of fluid therethrough.
摘要翻译：阀组件包括阀套，可旋转阀控制构件和设置在其间的柔性阀构件。阀控制构件和阀环对准以限定细长通道，并且柔性阀构件沿着通道设置。阀套环被构造成使得其至少一部分能够在与可旋转阀控制构件上的机构接合时具有径向挠曲。阀构件的一端固定在阀套上，另一端固定在可旋转阀控制件上。在可旋转阀控制构件相对于阀套环旋转时，可旋转阀控制构件的机构以这样的方式接合阀环部分，使得阀套部分沿径向方向弯曲并且由此产生触感，并且柔性阀构件从打开位置收缩到其中柔性阀构件开口至少部分地关闭以使流体通过其中的位置。

8. 发明授权

US06887268B2 Extension prosthesis for an arterial repair 有权
标题翻译：扩张假体用于动脉修复
公开(公告)号：US06887268B2
公开(公告)日：2005-05-03
申请号：US10041124
申请日：2002-01-08
申请人： Frank Butaric , William L. Howat , Marc Ramer , Kenneth S Solovay
发明人： Frank Butaric , William L. Howat , Marc Ramer , Kenneth S Solovay
IPC分类号： A61B17/064 , A61B17/068 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/848 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/95
CPC分类号： A61F2/07 , A61B17/064 , A61B17/0682 , A61F2/064 , A61F2/848 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/825 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2220/0075 , A61F2230/001 , A61F2230/0013 , A61F2230/005 , A61F2250/006
摘要： An endoluminal aneurysm treatment system of an expandable bypass prosthesis and an extension prosthesis with a flared distal portion which, upon expansion, frictionally engages the proximal end of the bypass prosthesis.
摘要翻译：可扩张旁路假体的腔内动脉瘤治疗系统和具有扩张远侧部分的延伸假体，其在膨胀时摩擦地接合旁路假体的近端。

9. 发明授权

US08343136B2 Introducer sheath with encapsulated reinforcing member 有权
标题翻译：引导器鞘与封装的加强构件
公开(公告)号：US08343136B2
公开(公告)日：2013-01-01
申请号：US12198484
申请日：2008-08-26
申请人： William L. Howat , David Christian Lentz
发明人： William L. Howat , David Christian Lentz
IPC分类号： A61M25/00
CPC分类号： A61M25/0045 , A61M25/00 , A61M25/0012 , A61M25/005 , A61M25/0662
摘要： An introducer sheath and a method for making the sheath. The sheath includes a fluoropolymer liner having a passageway extending longitudinally therethrough. An inner jacket is positioned longitudinally over the liner, and the inner surface of the inner jacket is bonded to the outer surface of the liner. An outer jacket is positioned longitudinally over the inner jacket, and the inner surface of the outer jacket is bonded to the outer surface of the inner jacket. A reinforcing coil is encapsulated within the inner jacket and the outer jacket.
摘要翻译：引导器护套和制造护套的方法。护套包括氟聚合物衬垫，其具有纵向延伸通过的通道。内护套纵向设置在衬套上方，并且内护套的内表面结合到衬套的外表面。外护套纵向设置在内护套的上方，外护套的内表面结合到内护套的外表面。加强线圈封装在内护套和外护套内。

10. 发明申请

US20100145429A1 Introducer sheath and method of manufacture 审中-公开
标题翻译：导引鞘和制造方法
公开(公告)号：US20100145429A1
公开(公告)日：2010-06-10
申请号：US12316114
申请日：2008-12-09
申请人： Manjiri A. Dhoke , William L. Howat , Cleve Koehler , Fred T. Parker
发明人： Manjiri A. Dhoke , William L. Howat , Cleve Koehler , Fred T. Parker
IPC分类号： A61F2/84 , B29C59/00 , B32B37/00
CPC分类号： B29C59/043 , A61F2/95 , A61F2/966
摘要： The present invention relates to a medical device delivery system. The delivery system includes an introducer sheath having an elongated tubular member having a passageway extending generally longitudinally therethrough. The passageway is defined by an inner surface of the tubular member and is configured to receive a medical device moveably disposed therein, where at least a portion of the inner surface of the inner tube comprises a non-uniform surface configured to reduce surface contact between the inner surface and the medical device. The delivery system includes an inner catheter configured to slidably extend throughout the passageway of the introducer sheath. A prosthesis is disposed within a distal portion of the introducer sheath, where the prosthesis is supported within the introducer sheath by the inner catheter.
摘要翻译：本发明涉及一种医疗器械输送系统。输送系统包括导引鞘，其具有细长的管状构件，该管状构件具有大致纵向延伸通过的通道。通道由管状构件的内表面限定，并且构造成容纳可移动地设置在其中的医疗装置，其中内管的内表面的至少一部分包括不均匀的表面，其被构造成减少内表面和医疗设备。输送系统包括构造成可滑动地延伸穿过导引器鞘的通道的内导管。假体设置在引导器护套的远侧部分内，其中假体通过内导管支撑在引导器护套内。

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