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1. 发明授权

US07945022B2 Radiation therapy plan dose perturbation system and method 有权
标题翻译：辐射治疗计划剂量扰动系统及方法
公开(公告)号：US07945022B2
公开(公告)日：2011-05-17
申请号：US12402785
申请日：2009-03-12
申请人： Benjamin E. Nelms , William E. Simon
发明人： Benjamin E. Nelms , William E. Simon
IPC分类号： A61N5/10
CPC分类号： A61N5/1071 , A61N5/1038 , A61N2005/1034 , A61N2005/1076
摘要： A method of determining a patient dose during or prior to therapy from an external radiation beam includes determining a dose distribution from a patient plan as delivered in a QA phantom at each appropriate beam angle and comparing the dose distribution determined from measurements or calculations to a corresponding treatment planning system (TPS) dose modeled distribution in the QA phantom and providing a correction distribution when applied to the TPS dose modeled distribution results in the dose distribution determined. The correction distribution may optionally be interpolated to non-measured points for each beam angle and geometrically projected toward the source of radiation through a volume that equals a dose volume of the TPS for a patient beam for each beam angle. The correction distribution is applied to the TPS patient dose volume for each beam angle for providing a corrected dose distribution in the patient.
摘要翻译：从外部辐射束确定治疗期间或之前的患者剂量的方法包括确定在每个适当的束角度下以质量检验模型传递的患者计划的剂量分布，并将从测量或计算确定的剂量分布与相应的治疗计划系统（TPS）剂量建模分布在QA体模中，并在应用于TPS剂量建模分布结果时提供校正分布，确定剂量分布。校正分布可以可选地内插到每个波束角的非测量点，并且通过相当于用于每个波束角度的患者波束的TPS的剂量体积的体积朝向辐射源几何投影。校正分布被应用于每个波束角的TPS患者剂量体积，以在患者体内提供校正的剂量分布。

2. 发明申请

US20090252292A1 RADIATION THERAPY PLAN DOSE PERTURBATION SYSTEM AND METHOD 有权
标题翻译：辐射治疗计划剂量刺激系统及方法
公开(公告)号：US20090252292A1
公开(公告)日：2009-10-08
申请号：US12402785
申请日：2009-03-12
申请人： William E. Simon , Benjamin E. Nelms
发明人： William E. Simon , Benjamin E. Nelms
IPC分类号： A61N5/10 , H05G1/42 , G01T1/02
CPC分类号： A61N5/1071 , A61N5/1038 , A61N2005/1034 , A61N2005/1076
摘要： A method of determining a patient dose during or prior to therapy from an external radiation beam includes determining a dose distribution from a patient plan as delivered in a QA phantom at each appropriate beam angle and comparing the dose distribution determined from measurements or calculations to a corresponding treatment planning system (TPS) dose modeled distribution in the QA phantom and providing a correction distribution when applied to the TPS dose modeled distribution results in the dose distribution determined. The correction distribution may optionally be interpolated to non-measured points for each beam angle and geometrically projected toward the source of radiation through a volume that equals a dose volume of the TPS for a patient beam for each beam angle. The correction distribution is applied to the TPS patient dose volume for each beam angle for providing a corrected dose distribution in the patient.
摘要翻译：从外部辐射束确定治疗期间或之前的患者剂量的方法包括确定在每个适当的束角度下以质量检验模型传递的患者计划的剂量分布，并将从测量或计算确定的剂量分布与相应的治疗计划系统（TPS）剂量建模分布在QA体模中，并在应用于TPS剂量建模分布结果时提供校正分布，确定剂量分布。校正分布可以可选地内插到每个波束角的非测量点，并且通过相当于用于每个波束角度的患者波束的TPS的剂量体积的体积朝向辐射源几何投影。校正分布被应用于每个波束角的TPS患者剂量体积，以在患者体内提供校正的剂量分布。

3. 发明授权

US08121253B2 Radiation therapy using beam modifiers placed against a patient's skin 有权
标题翻译：使用光束调节剂放置在患者皮肤上的放射治疗
公开(公告)号：US08121253B2
公开(公告)日：2012-02-21
申请号：US12695372
申请日：2010-01-28
申请人： Benjamin E. Nelms
发明人： Benjamin E. Nelms
IPC分类号： A61N5/04
CPC分类号： A61N5/103 , A61N5/1042 , A61N2005/1096
摘要： A method for making a beam modifier to be used in radiation therapy includes defining a region of interest in a patient that is to receive radiation, with the region of interest being defined using an anatomy coordinate system format. Radiation treatment parameters are defined for the defined region of interest, and correspond to an initial type beam modifier to be coupled to an output of a radiation device. Design data on a beam modifier to be placed on the skin of the patient is generated, with the design data being based on the defined region of interest and the defined radiation treatment parameters for the defined region of interest. The design data is in the same anatomy coordinate system format as the defined region of interest that is to receive the radiation. The design data is treated as a new region of interest, and the radiation dosage to be applied to the new region of interest is re-calculated while taking into account the beam modifier to be placed on the skin of the patient.
摘要翻译：用于制造用于放射治疗的光束修改器的方法包括定义要接收辐射的患者中的感兴趣区域，利用解剖坐标系统格式来定义关注区域。对于所定义的感兴趣区域定义辐射处理参数，并且对应于要耦合到辐射装置的输出的初始类型光束修正器。产生要放置在患者皮肤上的束修饰符的设计数据，其中设计数据基于所定义的感兴趣区域和所定义的感兴趣区域的定义的辐射治疗参数。设计数据处于与要接收辐射的定义的感兴趣区域相同的解剖坐标系统格式。将设计数据视为新的感兴趣区域，并且将新的感兴趣区域的辐射剂量重新计算，同时考虑放置在患者皮肤上的束调节剂。

4. 发明申请

US20090297014A1 SYSTEM FOR ASSESSING RADIATION TREATMENT PLAN SEGMENTATIONS 有权
标题翻译：评估辐射治疗计划分类系统
公开(公告)号：US20090297014A1
公开(公告)日：2009-12-03
申请号：US12475139
申请日：2009-05-29
申请人： Benjamin E. Nelms , Neal R. Miller , Jeffrey H. Manion
发明人： Benjamin E. Nelms , Neal R. Miller , Jeffrey H. Manion
IPC分类号： G06K9/00
CPC分类号： G06F19/321 , G06F19/00 , G06K9/6202 , G06K9/6215 , G06K2209/05 , G06T7/11 , G06T2207/10072 , G06T2207/30004
摘要： Segmentations used to describe structures to be treated by radiotherapy are evaluated by converting the segmentations into volume models and examining volume elements that are extra or missing in the volume model of the second segmentation with respect to the volume model of the first segmentation. This characterization of volume elements may be displayed graphically to show differences in segmentations for training or evaluation purposes and may be quantified by a metric method tallying volume elements as optionally weighted by distance from volume elements shared by the segmentation.
摘要翻译：用于描述通过放射疗法治疗的结构的分段通过将分割转换成体积模型并且相对于第一分割的体积模型检查第二分割的体积模型中额外或缺失的体积元素来评估。体积元素的这种表征可以以图形方式显示，以显示用于训练或评估目的的分段的差异，并且可以通过统计体积元素的度量方法来量化，所述度量方法可选地由距离由分割共享的体积元素加权。

5. 发明授权

US08130905B1 Dosimetry system and method for radiation therapy 有权
标题翻译：放射治疗剂量测定系统及方法
公开(公告)号：US08130905B1
公开(公告)日：2012-03-06
申请号：US12274823
申请日：2008-11-20
申请人： Benjamin E. Nelms
发明人： Benjamin E. Nelms
IPC分类号： A61N5/10
CPC分类号： A61N5/1075 , A61N2005/1054
摘要： Electronic portal imaging device (EPID) images are converted to an absolute dose at a simulated absolute dose plane in a measurement phantom for supporting intensity modulated radio therapy (IMRT) dose quality assurance (QA) by geometrically projecting the EPID image as may be needed, generating an output factor correction map specific to a radiation treatment beam, multiplying an EPID image by the output factor correction map for generating an output corrected EPID image, and convolving the output corrected EPID image with a redistribution kernel for generating a relative dose at a preselected dose plane. A wide field calibration map is then applied to the relative dose for generating an absolute dose at the preselected dose plane location.
摘要翻译：电子门户成像设备（EPID）图像在用于支持强度调制放射治疗（IMRT）剂量质量保证（QA）的模拟绝对剂量平面上被转换为绝对剂量，通过几何投影可能需要的EPID图像，产生特定于辐射治疗束的输出因子校正图，将EPID图像乘以输出因子校正图，以产生输出校正的EPID图像，以及将输出校正的EPID图像与再分布核心进行卷积，以产生预选的相对剂量剂量平面。然后将宽场校准图应用于在预选剂量平面位置处产生绝对剂量的相对剂量。

6. 发明授权

US08081813B2 System for assessing radiation treatment plan segmentations 有权
标题翻译：放射治疗计划分段评估系统
公开(公告)号：US08081813B2
公开(公告)日：2011-12-20
申请号：US12475139
申请日：2009-05-29
申请人： Benjamin E. Nelms , Neal R. Miller , Jeffrey H. Manion
发明人： Benjamin E. Nelms , Neal R. Miller , Jeffrey H. Manion
IPC分类号： G06K9/00 , A61N5/10
CPC分类号： G06F19/321 , G06F19/00 , G06K9/6202 , G06K9/6215 , G06K2209/05 , G06T7/11 , G06T2207/10072 , G06T2207/30004
摘要： Segmentations used to describe structures to be treated by radiotherapy are evaluated by converting the segmentations into volume models and examining volume elements that are extra or missing in the volume model of the second segmentation with respect to the volume model of the first segmentation. This characterization of volume elements may be displayed graphically to show differences in segmentations for training or evaluation purposes and may be quantified by a metric method tallying volume elements as optionally weighted by distance from volume elements shared by the segmentation.
摘要翻译：用于描述通过放射疗法治疗的结构的分段通过将分割转换成体积模型并且相对于第一分割的体积模型检查第二分割的体积模型中额外或缺失的体积元素来评估。体积元素的这种表征可以以图形方式显示，以显示用于训练或评估目的的分段的差异，并且可以通过统计体积元素的度量方法来量化，所述度量方法可选地由距离由分割共享的体积元素加权。

7. 发明申请

US20100049549A1 PATIENT-CUSTOMIZED MEDICAL TREATMENT EDUCATION SYSTEM AND METHODS 审中-公开
标题翻译：患者自定义医疗治疗教育系统与方法
公开(公告)号：US20100049549A1
公开(公告)日：2010-02-25
申请号：US12545962
申请日：2009-08-24
申请人： Benjamin E. Nelms
发明人： Benjamin E. Nelms
IPC分类号： G06Q50/00
CPC分类号： G06Q50/22 , G06Q10/10 , G06Q50/24
摘要： A system and methods for generating a patient-specific and treatment plan-specific educational media montage for radiation is provided. The montage provides a multi-media documentary containing data specific to the radiation therapy treatment of a particular patient, which is based upon the specific medical scenario for that patient. Information relating to the patient's expectations before, during and after treatment is included. DICOM RT files are converted by the system and utilized for providing an educational documentary that is customizable to each patient.
摘要翻译：提供了一种用于产生用于辐射的患者特异性和治疗计划特定教育媒体蒙太奇的系统和方法。该蒙太奇提供了一种多媒体纪录片，其中包含特定于特定患者的放射治疗治疗的数据，这是基于该病人的具体医疗情况。包括治疗前，治疗期间和治疗后患者预期的资料。 DICOM RT文件由系统转换并用于提供可针对每个患者定制的教育纪录片。

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