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1. 发明授权

US5057084A Implantable infusion device 失效
标题翻译：植入式输液装置
公开(公告)号：US5057084A
公开(公告)日：1991-10-15
申请号：US487541
申请日：1990-03-01
申请人： William D. Ensminger , James A. Knol , James C. Andrews
发明人： William D. Ensminger , James A. Knol , James C. Andrews
IPC分类号： A61M39/02 , A61M39/06
CPC分类号： A61M39/0606 , A61M39/0208 , A61M2039/0211 , A61M2039/062 , A61M2039/0633 , A61M2039/064 , A61M2039/0653 , A61M2039/0666 , A61M2039/0686
摘要： An infusion part for implantation adapted for providing repeated access to specific tissue within a patient and communicating with the tissue by an internal implanted catheter. The infusion ports according to this invention incorporate an enlarged entrance orifice with a funnel shaped internal cavity which narrows down to a reduced diameter passageway. An articulating catheter valve is provided within the passageway which normally prevents the flow of fluids through the valve but can be penetrated by an external introduced filament such as a catheter. After implantation, an external filament which is fed through an incision in the patient as is guided by the port internal cavity into registry with the catheter valve. Continued feeding of the filament causes the catheter to pass through the valves. Thereafter, when a catheter is inserted, therapeutic agents infused within the patient, or body fluids can be withdrawn. Alternate embodiments disclose means for providing a change in direction of the an introduced filament inserted through the infusion device. Additional embodiments disclose the concepts of providing a antimicrobial fluid bath within the device for prevention of infection and various approaches for securely connecting an internal catheter to an infusion port.
摘要翻译：一种用于植入的输注部件，其适于提供重复进入患者内的特定组织并通过内部植入导管与组织连通。根据本发明的输液端口包括具有漏斗形内腔的扩大进口孔，其缩小到直径减小的通道。在通道内设有一个关节式导管阀，通常可以防止流体流过阀门，但是可以被外部导入的细丝如导管穿透。在植入后，外部细丝通过口腔内腔中的切口进入患者的切口，与导管瓣膜对准。长丝的继续供给导致导管穿过阀门。此后，当插入导管时，可以撤出注入患者体内的治疗剂或体液。替代实施例公开了用于提供插入通过输注装置的引入的细丝的方向改变的装置。另外的实施方案公开了在装置内提供抗微生物流体浴以防止感染的概念和用于将内部导管牢固地连接到输注端口的各种方法。

2. 发明授权

US5356381A Implantable access devices 失效
标题翻译：可植入的接入设备
公开(公告)号：US5356381A
公开(公告)日：1994-10-18
申请号：US158042
申请日：1993-11-24
申请人： William D. Ensminger , James A. Knol , James C. Andrews
发明人： William D. Ensminger , James A. Knol , James C. Andrews
IPC分类号： A61M39/02 , A61M39/06 , A61M11/00
CPC分类号： A61M39/0606 , A61M39/0208 , A61M2039/0211 , A61M2039/062 , A61M2039/0633 , A61M2039/064 , A61M2039/0666 , A61M2039/0686
摘要： An access port (10) for implantation adapted for providing repeated access to specific tissue within a patient and communicating with the tissue by an internal implanted catheter (52). The access ports according to this invention incorporate an enlarged entrance orifice (13) with a funnel shaped internal cavity that narrows down to a reduced diameter passageway (18). An articulating catheter valve (24) is provided within the passageway which normally prevents the flow of fluids through the valve but which can be penetrated by an external introduced filament (32) such as a catheter. After implantation, an external filament (32) is introduced into the port (10) and guided by the passageway into registry with the catheter valve (24). Continued feeding of the filament (32) causes the filament to pass through the valve (24). Thereafter, with a catheter (32) inserted, therapeutic agents can be infused into the patient, or body fluids can be withdrawn. Alternate embodiments disclose various valve concepts (56) and means for providing a change in direction of an introduced filament inserted through the access device. Additional embodiments disclose the concepts of providing an antimicrobial fluid bath (98) within the device for prevention of infection and various approaches for securely connecting an internal catheter (52) to an access port.
摘要翻译：一种用于植入的进入口（10），其适于提供重复进入患者内的特定组织并通过内部植入的导管（52）与组织连通。根据本发明的进入端口包括具有漏斗形内部空腔的扩大的入口孔（13），其缩小到直径减小的通道（18）。在通道内设置有一个关节式导管阀（24），通常可以防止流体流过阀门，但是可以被外部引入的细丝（例如导管）穿透。植入后，将外部细丝（32）引入端口（10）并由通道引导与导管阀（24）对准。灯丝（32）的继续进给使灯丝通过阀门（24）。此后，在插入导管（32）的情况下，可以将治疗剂输入患者体内，或者可以取出体液。替代实施例公开了各种阀概念（56）和用于提供通过进入装置插入的引入的细丝的方向改变的装置。另外的实施方案公开了在装置内提供抗微生物流体浴（98）以防止感染的概念和用于将内部导管（52）牢固地连接到进入端口的各种方法。

3. 发明授权

US5256146A Vascular catheterization system with catheter anchoring feature 失效
标题翻译：具有导管锚固特征的血管导管系统
公开(公告)号：US5256146A
公开(公告)日：1993-10-26
申请号：US775045
申请日：1991-10-11
申请人： William D. Ensminger , James C. Andrews , James A. Knol
发明人： William D. Ensminger , James C. Andrews , James A. Knol
IPC分类号： A61B17/22 , A61M25/04 , A61M29/00
CPC分类号： A61M25/04 , A61B2017/22069 , A61B2017/2215
摘要： A patient implantable vascular catheterization system incorporating an anchoring element for maintaining the tip of an implanted catheter at a desired position within a blood vessel. The anchoring element comprises a deformable element such as a coiled wire or one or more expandable legs. The anchoring element is caused to assume a streamlined or compressed condition through placing it within an introducer catheter to facilitate placement or removal of the implanted catheter. Once positioned, the introducer catheter is retracted allowing the anchoring element to expand into engagement with the blood vessel. A material to induce occlusion of the blood vessel through clotting can be incorporated into the anchoring element.
摘要翻译：一种患者植入式血管导管插入系统，其包括用于将植入的导管的尖端保持在血管内的期望位置的锚固元件。锚定元件包括可变形元件，例如螺旋线或一个或多个可膨胀腿。锚定元件通过将锚定元件放置在导引器导管内而使其呈流线型或压缩状态，以便于植入的导管的放置或移除。一旦定位，导引器导管被缩回，允许锚定元件膨胀成与血管接合。通过凝血诱导血管闭塞的材料可以并入锚固元件中。

4. 发明授权

US5180365A Implantable infusion device 失效
标题翻译：可植入式输液装置
公开(公告)号：US5180365A
公开(公告)日：1993-01-19
申请号：US654661
申请日：1991-02-15
申请人： William D. Ensminger , James A. Knol , James C. Andrews
发明人： William D. Ensminger , James A. Knol , James C. Andrews
IPC分类号： A61M39/00 , A61M25/00 , A61M39/02 , A61M39/06
CPC分类号： A61M39/0606 , A61M39/0208 , A61M2039/0211 , A61M2039/062 , A61M2039/0633 , A61M2039/064 , A61M2039/0653 , A61M2039/0666 , A61M2039/0686
摘要： An infusion port designed for the introduction of a catheter for fluid infusion or removal or other flexible filaments within a patient. The infusion port is buried subcutaneously and accessed using a needle which introduces the filament. The infusion port has means to prevent the introducing needle from being inserted past a certain point within the port whereas the introduced flexible element can be inserted beyond that point and is caused to be forced through an articulating valve. The valve of this disclosure features enhancements in its sealing ability and in some embodiments provides a differing level of frictional engagement with the filament upon insertion versus withdrawal. The infusion port of this invention also has design features which provide a relatively small distance between the surface of the skin and the position of the articulating catheter valve through which the introduced filament passes.
摘要翻译：输液端口，设计用于引入用于流体输注或移除的导管或患者体内的其它柔性细丝。输注口被皮下埋藏并使用引入细丝的针进入。输液端口具有防止引入针穿过端口内的某一点的装置，而引入的柔性元件可被插入超过该点并且被迫通过关节式阀。本公开的阀的特征在于其密封能力的增强，并且在一些实施例中，在插入与抽出时提供与细丝的不同程度的摩擦接合。本发明的输液口还具有设计特征，其在皮肤表面与引入的细丝通过的关节式导管阀的位置之间提供相对小的距离。

5. 发明授权

US5226879A Implantable access device 失效
标题翻译：植入式接入设备
公开(公告)号：US5226879A
公开(公告)日：1993-07-13
申请号：US818626
申请日：1992-01-10
申请人： William D. Ensminger , James A. Knol , James C. Andrews , John J. Mastroeni
发明人： William D. Ensminger , James A. Knol , James C. Andrews , John J. Mastroeni
IPC分类号： A61M39/00 , A61M25/00 , A61M39/02 , A61M39/06
CPC分类号： A61M39/0208 , A61M39/0606 , A61M2039/0211 , A61M2039/062 , A61M2039/0633 , A61M2039/064 , A61M2039/0653 , A61M2039/0666 , A61M2039/0686
摘要： An infusion device which permits transcutaneous access to an implanted catheter for use in introducing an external filament such as a optical fiber, external catheter, guide wire or rigid needle. In accordance with this invention the device includes a valve assembly including a first valve element defining an aperture with a sealing member which is normally to engage and seal against the aperture. The sealing element is made from a hard material such as a metal. Upon introduction of a rigid external introducer such as a needle, the needle directly contacts the sealing member plug unsealing it from the valve element aperture which then closes against the external element. The device enables repeated access using a sharp introduced element such as a needle without it contacting soft sealing elements which could be degraded by such repeated access.
摘要翻译：输液装置，其允许经皮进入植入的导管，用于引入诸如光纤，外导管，导丝或刚性针的外部细丝。根据本发明，该装置包括阀组件，该阀组件包括限定孔的第一阀元件，该第一阀元件具有密封构件，该密封构件通常与孔接合并密封。密封元件由诸如金属的硬质材料制成。当引入诸如针的刚性外部引入器时，针直接接触密封构件插塞，从阀元件开口将其开封，然后阀封闭抵靠外部元件。该装置能够使用诸如针的尖锐引入元件来重复进入，而不会使其接触可能由于这种重复进入而劣化的软密封元件。

6. 发明授权

US5053013A Implantable infusion device 失效
标题翻译：植入式输液装置
公开(公告)号：US5053013A
公开(公告)日：1991-10-01
申请号：US539793
申请日：1990-06-18
申请人： William D. Ensminger , James A. Knol , James C. Andrews
发明人： William D. Ensminger , James A. Knol , James C. Andrews
IPC分类号： A61M39/02 , A61M39/06
CPC分类号： A61M39/0606 , A61M39/0208 , A61M2039/0211 , A61M2039/0223 , A61M2039/062 , A61M2039/0633 , A61M2039/064 , A61M2039/0653 , A61M2039/0686
摘要： In infusion port for implantation within a patient for providing repeated access to specific tissue within a patient and communicating with the tissue by an internal implanted catheter. The infusion port in accordance with this invention includes a housing having a funnel shaped inlet orifice which terminates in a reduced diameter guide passageway. Installed within the housing is an articulating catheter valve such as a leaflet valve assembly. The housing communicates with an exit passageway which is attached to an internal outflow catheter coupling the infusion port to a specific tissue within the patient. In use, a needle is used to penetrate the patient's skin and contacts the entrance orifice of the infusion port. The entrance orifice guides the needle point into alignment with and into the guide passageway. The guide passageway targets a small portion of the articulating catheter valve which can be in the form of a leaflet valve assembly. Once through the catheter valve, fluids may be infused into the patient through the needle or withdrawn from the patient. Alternatively, an external catheter or other filament can be placed in communication with the outflow catheter by feeding it in into the infusion port and into the implanted catheter after being introduced over a needle which is restricted from entering the implanted catheter.
摘要翻译：在用于植入患者体内的输液端口中，用于提供对患者内的特定组织的反复进入并通过内部植入导管与组织连通。根据本发明的输液口包括具有漏斗形入口孔的壳体，其终止于直径较小的引导通道。安装在壳体内的是诸如小叶瓣组件的关节式导管阀。外壳与出口通道连通，该出口通道连接到将输注端口连接到患者体内的特定组织的内部流出导管。在使用中，使用针穿透患者的皮肤并接触输液口的入口。入口孔引导针尖与引导通道对准并进入导向通道。引导通道瞄准可以是小叶瓣组件形式的关节式导管阀的一小部分。一旦通过导管阀，流体可以通过针注入患者体内或从患者身体抽出。或者，外部导管或其它细丝可以通过在被限制进入植入的导管的针上引入之后，通过将其输入到输注端口并进入植入的导管中而与流出导管连通。

7. 发明申请

US20120123342A1 IMPLANTABLE INJECTION PORT WITH TISSUE IN-GROWTH PROMOTER 有权
标题翻译：可注射注射口与组织生长促进剂
公开(公告)号：US20120123342A1
公开(公告)日：2012-05-17
申请号：US12946913
申请日：2010-11-16
申请人： James C. Andrews , Amy L. Marcotte , Sarah A. Noschang , Eric W. Thompson , Scott A. Woodruff , Michael J. Vendely
发明人： James C. Andrews , Amy L. Marcotte , Sarah A. Noschang , Eric W. Thompson , Scott A. Woodruff , Michael J. Vendely
IPC分类号： A61M5/32
CPC分类号： A61M39/0208 , A61M5/14276
摘要： A surgically implantable injection port has one or more tissue in-growth promoting surfaces. The injection port includes a housing, a fluid reservoir defined in part by the housing, a needle penetrable septum, and a tissue in-growth promoting surface integrally provided on an exterior surface of the port. The tissue in-growth promoting surface may be provided by surgical mesh or a textured surface on the injection port. The injection port may be used as part of a gastric band system or some other type of system.
摘要翻译：手术可植入的注射口具有一个或多个组织生长促进表面。注射口包括壳体，由壳体部分限定的流体储存器，可穿透针的隔膜以及一体地设置在口部的外表面上的组织生长促进表面。组织生长促进表面可以通过外科手术网或注射口上的纹理表面来提供。注射口可以用作胃束带系统或一些其他类型的系统的一部分。

8. 发明申请

US20120123197A1 Implantable injection port with tissue in-growth promoter 有权
标题翻译：具有组织生长促进剂的可植入注射口
公开(公告)号：US20120123197A1
公开(公告)日：2012-05-17
申请号：US12946923
申请日：2010-11-16
申请人： Scott A. Woodruff , Eric W. Thompson , Sarah A. Noschang , Amy L. Marcotte , Michael J. Vendely , James C. Andrews
发明人： Scott A. Woodruff , Eric W. Thompson , Sarah A. Noschang , Amy L. Marcotte , Michael J. Vendely , James C. Andrews
IPC分类号： A61F2/04
CPC分类号： A61F5/0056 , A61F2/0077 , A61M5/14276 , A61M39/0208 , A61M2039/0223 , A61M2039/0229 , A61M2039/0261
摘要： A surgically implantable injection port has a tissue in-growth promoting surface associated with a fluid conduit that is coupled to the injection port. The injection port includes a housing, a fluid reservoir defined in part by the housing, a needle penetrable septum, a fluid conduit in communication with the reservoir, and a tissue in-growth promoting surface coupled to the fluid conduit. The tissue in-growth promoting surface may be provided by surgical mesh wrapped around the conduit or through which the conduit is threaded. The injection port and the fluid conduit may be used as part of a gastric band system or some other type of system.
摘要翻译：手术可植入的注射口具有与流体导管相关联的组织生长促进表面，该流体导管联接到注射口。注射口包括壳体，由壳体部分限定的流体储存器，可穿透针的隔膜，与储存器连通的流体导管，以及联接到流体导管的组织生长促进表面。组织生长促进表面可以通过缠绕在导管上的外科手术网来提供，或通过该导管螺纹穿过。注射口和流体导管可以用作胃束带系统或一些其他类型的系统的一部分。

9. 发明授权

US08852217B2 Implantable injection port with tissue in-growth promoter 有权
标题翻译：具有组织生长促进剂的可植入注射口
公开(公告)号：US08852217B2
公开(公告)日：2014-10-07
申请号：US12946923
申请日：2010-11-16
申请人： Scott A. Woodruff , Eric W. Thompson , Sarah A. Noschang , Amy L. Marcotte , Michael J. Vendely , James C. Andrews
发明人： Scott A. Woodruff , Eric W. Thompson , Sarah A. Noschang , Amy L. Marcotte , Michael J. Vendely , James C. Andrews
IPC分类号： A61B17/08 , A61F2/00 , A61M5/32 , A61M37/00 , A61M31/00 , A61M5/142 , A61F5/00 , A61M39/02
CPC分类号： A61F5/0056 , A61F2/0077 , A61M5/14276 , A61M39/0208 , A61M2039/0223 , A61M2039/0229 , A61M2039/0261
摘要： A surgically implantable injection port has a tissue in-growth promoting surface associated with a fluid conduit that is coupled to the injection port. The injection port includes a housing, a fluid reservoir defined in part by the housing, a needle penetrable septum, a fluid conduit in communication with the reservoir, and a tissue in-growth promoting surface coupled to the fluid conduit. The tissue in-growth promoting surface may be provided by surgical mesh wrapped around the conduit or through which the conduit is threaded. The injection port and the fluid conduit may be used as part of a gastric band system or some other type of system.
摘要翻译：手术可植入的注射口具有与流体导管相关联的组织生长促进表面，该流体导管联接到注射口。注射口包括壳体，由壳体部分限定的流体储存器，可穿透针的隔膜，与储存器连通的流体导管，以及联接到流体导管的组织生长促进表面。组织生长促进表面可以通过缠绕在导管上的外科手术网来提供，或通过该导管螺纹穿过。注射口和流体导管可以用作胃束带系统或一些其他类型的系统的一部分。

10. 发明授权

US09022923B2 Implantable injection port with tissue in-growth promoter 有权
标题翻译：具有组织生长促进剂的可植入注射口
公开(公告)号：US09022923B2
公开(公告)日：2015-05-05
申请号：US12946913
申请日：2010-11-16
申请人： James C. Andrews , Amy L. Marcotte , Sarah A. Noschang , Eric W. Thompson , Scott A. Woodruff , Michael J. Vendely
发明人： James C. Andrews , Amy L. Marcotte , Sarah A. Noschang , Eric W. Thompson , Scott A. Woodruff , Michael J. Vendely
IPC分类号： A61F2/00 , A61F13/00 , A61M39/02 , A61M5/142
CPC分类号： A61M39/0208 , A61M5/14276
摘要： A surgically implantable injection port has one or more tissue in-growth promoting surfaces. The injection port includes a housing, a fluid reservoir defined in part by the housing, a needle penetrable septum, and a tissue in-growth promoting surface integrally provided on an exterior surface of the port. The tissue in-growth promoting surface may be provided by surgical mesh or a textured surface on the injection port. The injection port may be used as part of a gastric band system or some other type of system.
摘要翻译：手术可植入的注射口具有一个或多个组织生长促进表面。注射口包括壳体，由壳体部分限定的流体储存器，可穿透针的隔膜以及一体地设置在口部的外表面上的组织生长促进表面。组织生长促进表面可以通过外科手术网或注射口上的纹理表面来提供。注射口可以用作胃束带系统或一些其他类型的系统的一部分。

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