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1. 发明申请

US20080033534A1 Flexible Barb for Anchoring a Prosthesis 有权
标题翻译：用于锚定假体的弹性假肢
公开(公告)号：US20080033534A1
公开(公告)日：2008-02-07
申请号：US11849858
申请日：2007-09-04
申请人： William Cook , Michael DeBruyne , Mark Frye , Benjamin Nickless , Thomas Osborne , Ronan Young
发明人： William Cook , Michael DeBruyne , Mark Frye , Benjamin Nickless , Thomas Osborne , Ronan Young
IPC分类号： A61F2/06
CPC分类号： A61F2/86 , A61B2017/0412 , A61B2017/0437 , A61F2002/8483 , A61F2220/0016
摘要： A system for anchoring an endoluminal prosthesis comprises a barb. The barb comprises a base, a retractable body extending distally from the base towards a distal anchor, and a hinge disposed between the base and the anchor and spaced apart from the base. The anchor pivots about the hinge between a retracted configuration and an extended configuration. Additional devices, systems, and methods are disclosed.
摘要翻译：用于锚定内腔假体的系统包括倒钩。倒钩包括基部，从基部朝向远侧锚定件向远侧延伸的可伸缩体，以及设置在基部和锚固件之间并与基部间隔开的铰链。锚固件在缩回配置和延伸配置之间绕铰链枢转。公开了附加设备，系统和方法。

2. 发明申请

US20050159804A1 Multiple stitches for attaching stent to graft 审中-公开
标题翻译：用于将支架连接到移植物上的多个针迹
公开(公告)号：US20050159804A1
公开(公告)日：2005-07-21
申请号：US11038567
申请日：2005-01-18
申请人： Ashvin Lad , Michael DeBruyne , Thomas Osborne
发明人： Ashvin Lad , Michael DeBruyne , Thomas Osborne
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/075 , A61F2220/0041 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0067
摘要： An endoluminal prosthetic device is formed by attaching a stent to a graft. The stent is a plurality of struts and joints or apices between the struts. At least one apex of the stent may be attached to the graft with at least two stitches sharing a penetration in the graft. This more firmly anchors the stent to the graft, preventing separation of the stent from the graft. By using at least one opening or penetration in the graft for more than one stitch, the number of penetrations or openings in the graft is minimized. This has the advantage of maintaining as much as possible the integrity of the graft while minimizing leakage and complications.
摘要翻译：通过将支架附接到移植物来形成腔内假体装置。支架是支柱之间的多个支柱和关节或顶点。支架的至少一个顶点可以以至少两个共享移植物穿透的缝合连接到移植物。这更牢固地将支架固定到移植物上，防止支架与移植物分离。通过在移植物中使用至少一个开口或穿透多于一个针脚，使移植物中的穿孔或开口的数量最小化。这具有尽可能地保持移植物的完整性同时最小化渗漏和并发症的优点。

3. 发明申请

US20050273155A1 Endoluminal device with extracellular matrix material and methods 有权
标题翻译：腔内装置与细胞外基质材料及方法
公开(公告)号：US20050273155A1
公开(公告)日：2005-12-08
申请号：US11094021
申请日：2005-03-30
申请人： Clinton Bahler , Michael DeBruyne , Neal Fearnot , Alan Leewood , Jason Mead , Thomas Osborne , Jichao Sun
发明人： Clinton Bahler , Michael DeBruyne , Neal Fearnot , Alan Leewood , Jason Mead , Thomas Osborne , Jichao Sun
IPC分类号： A61F2/00 , A61F2/06
CPC分类号： A61F2/07 , A61F2/0077 , A61F2/848 , A61F2/89 , A61F2/915 , A61F2002/061 , A61F2002/065 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/0065
摘要： An endoluminal device comprises a stent and a tubular graft supported by the stent. The graft has a proximal and a distal opening and comprises a synthetic material and a bioremodelable material. The bioremodelable material is disposed on an exterior surface in at least one band adjacent at least one of the proximal and distal openings.
摘要翻译：腔内装置包括支架和由支架支撑的管状移植物。移植物具有近端和远端开口，并且包括合成材料和生物可重构材料。生物可重塑材料设置在邻近近端和远端开口中的至少一个的至少一个带中的外表面上。

4. 发明申请

US20050159803A1 Endoluminal prosthetic device 有权
标题翻译：腔内假体装置
公开(公告)号：US20050159803A1
公开(公告)日：2005-07-21
申请号：US11037792
申请日：2005-01-18
申请人： Ashvin Lad , Michael DeBruyne , Thomas Osborne
发明人： Ashvin Lad , Michael DeBruyne , Thomas Osborne
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/067 , A61F2002/075 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0067
摘要： An endoluminal prosthetic device for placement in a body lumen is formed by stitching stents to a graft. A first or anchoring stent is used for securing a graft made of biocompatible material that forms at least one lumen. There is also a second stent. The first and second stents each include a plurality of struts and apices between the struts. At least two of the apices in each of the first and second stents are secured to the graft by stitches. A running suture links at least one stitch of the first stent and one stitch of the second stent. The running suture linking the first stent and the second stent adds strength to the stitches and better secures the first stent to the device. The endoluminal prosthetic device may be used in an aortic vessel to treat stenoses or aneurysms.
摘要翻译：通过将支架缝合到移植物上而形成用于放置在体腔内的腔内假体装置。第一或锚固支架用于固定由形成至少一个腔的生物相容性材料制成的移植物。还有第二支架。第一和第二支架各自包括支柱之间的多个支柱和顶点。第一和第二支架中的每一个中的至少两个顶点通过针迹固定到移植物上。运行缝合线连接第一支架的至少一个线圈和第二支架的一个线圈。连接第一支架和第二支架的运行缝合线为线圈增加了强度，并且将第一支架更好地固定到装置。腔内修复装置可用于主动脉血管以治疗狭窄或动脉瘤。

5. 发明申请

US20060100660A1 Blood clot filter configured for a wire guide 审中-公开
标题翻译：血液凝块过滤器配置为导丝器
公开(公告)号：US20060100660A1
公开(公告)日：2006-05-11
申请号：US11268355
申请日：2005-11-07
申请人： Thomas Osborne , Mark Frye
发明人： Thomas Osborne , Mark Frye
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/005 , A61F2230/008
摘要： A filter to capture blood clots includes a hub with a passageway through which a wire guide is received. The filter also includes a plurality of primary struts and a plurality of secondary struts that extend from the hub. Each primary strut terminates with a hook to anchor the filter in the blood vessel when the filter is deployed in the blood vessel. The secondary struts center the filter in the blood vessel as the secondary struts engage the interior of the blood vessel during deployment of the filter in the vessel.
摘要翻译：用于捕获血块的过滤器包括具有通道的毂，所述通道通过所述通道接收线引导件。过滤器还包括从轮毂延伸的多个主支柱和多个次撑杆。当过滤器部署在血管中时，每个主支柱终止于钩子以将过滤器锚定在血管中。当过滤器在容器中展开期间，辅助支柱将过滤器置于血管中，因为辅助支柱接合血管内部。

6. 发明申请

US20050004504A1 Catheter for extracorporeal treatment 审中-公开
标题翻译：导管用于体外治疗
公开(公告)号：US20050004504A1
公开(公告)日：2005-01-06
申请号：US10874409
申请日：2004-06-23
申请人： Mark Frye , Bruce Gingles , Thomas Osborne , Jon Speer
发明人： Mark Frye , Bruce Gingles , Thomas Osborne , Jon Speer
IPC分类号： A61M1/36 , A61M37/00
CPC分类号： A61M1/3653 , A61M1/3659 , A61M1/3661
摘要： A catheter assembly for use in extracorporeal treatment of a bodily fluid. The catheter assembly includes a catheter body having an outer tubular member and an inner tubular member. At least one of the tubular members includes an expansion member, such as a malecot, for centering the catheter assembly in a body vessel. Body fluid is withdrawn from the vessel, and passed through one of the tubular members to a treatment instrument, such as a dialyzer. Treated fluid from the treatment instrument is then passed through the other tubular member and returned to the body vessel through one or more openings in said other tubular member.
摘要翻译：一种用于身体体液的体外治疗的导管组件。导管组件包括具有外部管状构件和内部管状构件的导管本体。管状构件中的至少一个包括用于将导管组件对准在体容器中的膨胀构件，例如马口油。将体液从容器中取出，并通过其中一个管状构件至诸如透析器的治疗仪器。然后将来自治疗仪器的处理过的液体通过另一个管状构件，并通过所述另一个管状构件中的一个或多个开口返回到身体容器。

7. 发明授权

US08214346B2 Personalization engine for classifying unstructured documents 有权
标题翻译：用于分类非结构化文档的个性化引擎
公开(公告)号：US08214346B2
公开(公告)日：2012-07-03
申请号：US12362840
申请日：2009-01-30
申请人： Tushar Pradhan , Thomas Osborne , John Potter
发明人： Tushar Pradhan , Thomas Osborne , John Potter
IPC分类号： G06F7/00
CPC分类号： G06F17/30011 , G06F17/30598 , G06F17/30699 , G06F17/30707
摘要： Unstructured electronic documents are classified for profiling and targeting users for additional relevant content. Behavioral data is gathered from user activity, and user documents and actions are categorized. Profile information is combined with collaborative and editorial data to provide users with credible information regarding products. Author-generated document classification information is analyzed and assigned a first taxonomic noun to characterize the document. User-generated tags characterizing a portion of the document are assigned a second taxonomic noun. Search terms that resulted in the user accessing the document are identified and assigned a third taxonomic noun. Attributes related to how the document was accessed are evaluated and assigned a fourth taxonomic noun. The document is processed using pattern rules to extract a fifth taxonomic noun. The taxonomic nouns are aggregated to determine term vectors representing the document, and the document is categorized using the term vectors, the taxonomic nouns, or the author-generated classification.
摘要翻译：非结构化电子文档被分类为用于分析和定位用户以获得更多相关内容。从用户活动中收集行为数据，并对用户文档和操作进行分类。简档信息与协作和编辑数据相结合，为用户提供有关产品的可靠信息。作者生成的文档分类信息被分析并分配了第一个分类名词来表征文档。表征文档的一部分的用户生成的标签被分配了第二个分类名词。导致用户访问该文档的搜索字词被识别并分配了第三个分类名词。与文档访问相关的属性被评估并分配了第四个分类名词。使用模式规则处理文档以提取第五个分类名词。聚合分类学名词以确定表示文档的术语向量，并使用术语向量，分类名词或作者生成的分类对文档进行分类。

8. 发明申请

US20070191929A1 Medical devices using magnetic pulse welding 审中-公开
标题翻译：医疗器械采用磁脉冲焊接
公开(公告)号：US20070191929A1
公开(公告)日：2007-08-16
申请号：US10922567
申请日：2004-11-22
申请人： Thomas Osborne , Andrew Herald , Scott Eells
发明人： Thomas Osborne , Andrew Herald , Scott Eells
IPC分类号： A61F2/90
CPC分类号： B23K13/02
摘要： Medical devices for use in or on a mammalian body have improved properties through the use of magnetic pulse welding to join components. The improved properties include increased strength, corrosion resistance, and preservation of material characteristics. A method of forming a medical device using magnetic pulse welding is also provided.
摘要翻译：用于哺乳动物体内或哺乳动物身体的医疗装置通过使用磁脉冲焊接来连接部件而具有改进的性能。改进的性能包括提高强度，耐腐蚀性和保存材料特性。还提供了使用磁脉冲焊接形成医疗装置的方法。

9. 发明申请

US20060142846A1 Implantable vascular device 有权
公开(公告)号：US20060142846A1
公开(公告)日：2006-06-29
申请号：US11165600
申请日：2005-06-22
申请人： Dusan Pavcnik , Frederick Keller , Josef Rosch , Thomas Osborne , Brian Bates , John DeFord , Christopher Dixon , Andrew Hoffa , Raymond Leonard , Joseph Obermiller
发明人： Dusan Pavcnik , Frederick Keller , Josef Rosch , Thomas Osborne , Brian Bates , John DeFord , Christopher Dixon , Andrew Hoffa , Raymond Leonard , Joseph Obermiller
IPC分类号： A61F2/06
CPC分类号： A61F2/01 , A61F2/2418 , A61F2/2475 , A61F2002/018 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0008 , A61F2230/001 , A61F2230/0023 , A61F2230/0026 , A61F2230/0054 , A61F2230/0058 , A61F2230/0095 , Y10S623/901
摘要： A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame using heat or pressure welding crimping, adhesive, or other techniques to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.

10. 发明申请

US20060136044A1 Medical device with bioactive agent 有权
公开(公告)号：US20060136044A1
公开(公告)日：2006-06-22
申请号：US11244991
申请日：2005-10-06
申请人： Thomas Osborne , Jacob Flagle , Brian Case , Joseph Obermiller , Ram Paul
发明人： Thomas Osborne , Jacob Flagle , Brian Case , Joseph Obermiller , Ram Paul
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/0016 , A61F2230/0026 , A61F2230/0067 , A61F2230/008 , A61F2230/0095 , A61F2250/0067
摘要： Medical devices with one or more bioactive agents are provided for regulating fluid flow through a body vessel. Medical devices according to the invention can comprise prosthetic valves that include a bioactive agent.

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