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1. 发明授权

US09216293B2 Delivery system assemblies for implantable medical devices 有权
标题翻译：可植入医疗器械的输送系统组件
公开(公告)号：US09216293B2
公开(公告)日：2015-12-22
申请号：US13298821
申请日：2011-11-17
申请人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin , James C. Allan
发明人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin , James C. Allan
IPC分类号： A61B19/00 , A61N1/372 , A61B5/00 , A61B5/042 , A61N1/375
CPC分类号： A61N1/37205 , A61B5/0422 , A61B5/6869 , A61B5/6882 , A61B2560/066 , A61M25/0136 , A61M25/0147 , A61N1/3756
摘要： An inner subassembly of a delivery system assembly extends within a lumen of an elongate outer tube of the assembly, and includes a flared distal end, which is preferably configured to conform to a proximal end of an implantable medical device; a distal-most portion of the outer tube is sized to contain both the flared distal end and an entirety of the medical device. The inner subassembly includes a core, an elongate pull-wire, extending along the core, and a sheath surrounding the pull-wire and the core; the sheath includes a slot opening that allows the pull-wire to pass laterally therethrough. The assembly preferably has a pre-formed curvature along a length of the sheath, and the slot opening extends along the pre-formed curvature. The outer tube is longitudinally moveable relative to the inner subassembly, for example, to deploy the medical device.
摘要翻译：输送系统组件的内部子组件在组件的细长外管的内腔中延伸，并且包括扩口远端，其优选地构造成符合可植入医疗装置的近端; 外管的最远部分的尺寸被设计成容纳扩张的远端和整个医疗装置。所述内部子组件包括芯，沿所述芯延伸的细长拉线和围绕所述拉线和所述芯的护套; 护套包括允许拉线横向通过的槽口。组件优选地沿着护套的长度具有预先形成的曲率，并且槽开口沿着预先形成的曲率延伸。外管可相对于内部子组件纵向移动，例如，以部署医疗装置。

2. 发明申请

US20130131693A1 DELIVERY SYSTEM ASSEMBLIES FOR IMPLANTABLE MEDICAL DEVICES 有权
标题翻译：用于可植入医疗器械的输送系统组件
公开(公告)号：US20130131693A1
公开(公告)日：2013-05-23
申请号：US13298821
申请日：2011-11-17
申请人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin , James C. Allan
发明人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin , James C. Allan
IPC分类号： A61B19/00
CPC分类号： A61N1/37205 , A61B5/0422 , A61B5/6869 , A61B5/6882 , A61B2560/066 , A61M25/0136 , A61M25/0147 , A61N1/3756
摘要： An inner subassembly of a delivery system assembly extends within a lumen of an elongate outer tube of the assembly, and includes a flared distal end, which is preferably configured to conform to a proximal end of an implantable medical device; a distal-most portion of the outer tube is sized to contain both the flared distal end and an entirety of the medical device. The inner subassembly includes a core, an elongate pull-wire, extending along the core, and a sheath surrounding the pull-wire and the core; the sheath includes a slot opening that allows the pull-wire to pass laterally therethrough. The assembly preferably has a pre-formed curvature along a length of the sheath, and the slot opening extends along the pre-formed curvature. The outer tube is longitudinally moveable relative to the inner subassembly, for example, to deploy the medical device.
摘要翻译：输送系统组件的内部子组件在组件的细长外管的内腔中延伸，并且包括扩口远端，其优选地构造成符合可植入医疗装置的近端; 外管的最远部分的尺寸被设计成容纳扩张的远端和整个医疗装置。所述内部子组件包括芯，沿所述芯延伸的细长拉线和围绕所述拉线和所述芯的护套; 护套包括允许拉线横向通过的槽口。组件优选地沿着护套的长度具有预先形成的曲率，并且槽开口沿着预先形成的曲率延伸。外管可相对于内部子组件纵向移动，例如，以部署医疗装置。

3. 发明申请

US20130131591A1 DELIVERY SYSTEM ASSEMBLIES AND ASSOCIATED METHODS FOR IMPLANTABLE MEDICAL DEVICES 有权
标题翻译：用于可植入医疗器械的输送系统组件和相关方法
公开(公告)号：US20130131591A1
公开(公告)日：2013-05-23
申请号：US13298973
申请日：2011-11-17
申请人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin
发明人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin
IPC分类号： A61M25/092 , A61M25/01 , A61M25/098
CPC分类号： A61N1/0587 , A61B2017/00331 , A61K9/0024 , A61M5/14276 , A61M25/0041 , A61M25/0102 , A61M25/0147 , A61M31/00 , A61N1/3622 , A61N1/37205 , A61N1/3756 , A61N2001/0578
摘要： A delivery system assembly includes an elongate outer tube, an elongate inner member extending within a lumen of the outer tube, and an articulation sheath surrounding the outer tube between a handle of the assembly and a distal-most portion of the outer tube. The outer tube is longitudinally moveable within the sheath; and an inner diameter of the sheath is preferably smaller than that of the handle and the distal-most portion of the outer tube. Navigation of the assembly through a venous system, for deployment of an implantable medical device, is facilitated by deflection of the sheath, to orient a distal-most portion of the outer tube, within which an entirety of the medical device is contained/loaded, and by subsequent advancement of the distal-most portion, with respect to the sheath, to move the distal end of the inner member, along with the contained/loaded device into proximity with a target implant site.
摘要翻译：输送系统组件包括细长的外管，在外管的内腔内延伸的细长内部构件，以及围绕组件的手柄和外管的最远部分之间的外管围绕的关节护套。外管可在鞘内纵向移动; 并且护套的内径优选地小于手柄和外管的最远部分的内径。通过静脉系统的导引，用于部署可植入医疗装置，通过护套的偏转来促进，以使外管的最远端部分定向，其中整个医疗装置被包含/装载在该外管的最远部分，并且通过相对于护套随后推进最远部分，将内部构件的远端与所容纳/加载的装置一起移动到目标植入部位附近。

4. 发明授权

US08721587B2 Delivery system assemblies and associated methods for implantable medical devices 有权
标题翻译：可植入医疗器械的输送系统组件和相关方法
公开(公告)号：US08721587B2
公开(公告)日：2014-05-13
申请号：US13298973
申请日：2011-11-17
申请人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin
发明人： William A. Berthiaume , H. Allan Steingisser , Don H. Tran , Erik Griswold , Brent L. Locsin
IPC分类号： A61M25/01 , A61M31/00 , A61M5/142 , A61K9/00
CPC分类号： A61N1/0587 , A61B2017/00331 , A61K9/0024 , A61M5/14276 , A61M25/0041 , A61M25/0102 , A61M25/0147 , A61M31/00 , A61N1/3622 , A61N1/37205 , A61N1/3756 , A61N2001/0578
摘要： A delivery system assembly includes an elongate outer tube, an elongate inner member extending within a lumen of the outer tube, and an articulation sheath surrounding the outer tube between a handle of the assembly and a distal-most portion of the outer tube. The outer tube is longitudinally moveable within the sheath; and an inner diameter of the sheath is preferably smaller than that of the handle and the distal-most portion of the outer tube. Navigation of the assembly through a venous system, for deployment of an implantable medical device, is facilitated by deflection of the sheath, to orient a distal-most portion of the outer tube, within which an entirety of the medical device is contained/loaded, and by subsequent advancement of the distal-most portion, with respect to the sheath, to move the distal end of the inner member, along with the contained/loaded device into proximity with a target implant site.
摘要翻译：输送系统组件包括细长的外管，在外管的内腔内延伸的细长内部构件，以及围绕组件的手柄和外管的最远部分之间的外管围绕的关节护套。外管可在鞘内纵向移动; 并且护套的内径优选地小于手柄和外管的最远部分的内径。通过静脉系统的导引，用于部署可植入医疗装置，通过护套的偏转来促进，以使外管的最远端部分定向，其中整个医疗装置被包含/装载在该外管的最远部分，并且通过相对于护套随后推进最远部分，将内部构件的远端与所容纳/加载的装置一起移动到目标植入部位附近。

5. 发明申请

US20130079798A1 DELIVERY SYSTEM ASSEMBLIES FOR IMPLANTABLE MEDICAL DEVICES 有权
标题翻译：用于可植入医疗器械的输送系统组件
公开(公告)号：US20130079798A1
公开(公告)日：2013-03-28
申请号：US13239990
申请日：2011-09-22
申请人： Don H. Tran , William A. Berthiaume , H. Allan Steingisser , Maria Valdovinos , Brent L. Locsin , Suruchi Anand
发明人： Don H. Tran , William A. Berthiaume , H. Allan Steingisser , Maria Valdovinos , Brent L. Locsin , Suruchi Anand
IPC分类号： A61B19/00
CPC分类号： A61B17/3468 , A61N1/362 , A61N1/37205 , A61N1/3756
摘要： A delivery system assembly includes an elongate inner member that extends distally through a lumen of an elongate outer tube of the assembly; the outer tube is moveable relative to the inner member between first and second positions to deploy an implantable medical device that is held within the outer tube lumen. The inner member may include a flared distal end that abuts, and preferably conforms to, the proximal end of the device, when the device is held within the outer tube lumen. The assembly further includes a stability sheath that surrounds a limited length of the outer tube, in proximity to the handle, to provide an interface for both an operator, who handles the assembly, and for an introducer sheath that provides passage for the assembly into the venous system, so that movement of the outer tube is not hindered by either during device deployment.
摘要翻译：输送系统组件包括细长的内部构件，其向远侧延伸穿过组件的细长外管的内腔; 外管可在第一和第二位置之间相对于内部构件移动以展开保持在外管内腔内的可植入医疗装置。当装置保持在外管腔内时，内部构件可以包括邻近并且优选地符合装置的近端的扩口远端。组件还包括稳定的护套，其围绕外管的有限长度围绕手柄，以提供用于处理组件的操作者和导引器护套的接口，所述引导器护套为组件提供通道静脉系统，使得在设备部署期间外部管的运动不会受到阻碍。

6. 发明申请

US20130103047A1 DELIVERY SYSTEM ASSEMBLIES AND ASSOCIATED METHODS FOR IMPLANTABLE MEDICAL DEVICES 有权
公开(公告)号：US20130103047A1
公开(公告)日：2013-04-25
申请号：US13279835
申请日：2011-10-24
申请人： H. Allan Steingisser , Don H. Tran , William A. Berthiaume , Brent L. Locsin
发明人： H. Allan Steingisser , Don H. Tran , William A. Berthiaume , Brent L. Locsin
IPC分类号： A61B19/00
CPC分类号： A61N1/37205 , A61N1/3622 , A61N1/3756 , A61N2001/0578
摘要： A delivery system assembly includes an outer tube, an inner member, extending within a lumen of the outer tube, and a deflectable shaft, extending within the outer tube lumen and around the inner member; the tube and inner member are longitudinally moveable with respect to the shaft, and a distal end of the inner member is located distal to the shaft within the tube lumen. A medical device can be loaded into the tube lumen, along a distal-most portion of the tube, and contained between the inner member and a distal opening of the tube lumen. Deflecting the shaft orients the distal-most portion for navigation of the assembly, and, when the distal end of the inner member is engaged within the tube lumen, distal movement of the tube, with respect to the shaft, causes similar distal movement of the inner member and the loaded medical device toward an implant site.

7. 发明授权

US08945146B2 Delivery system assemblies and associated methods for implantable medical devices 有权
标题翻译：可植入医疗器械的输送系统组件和相关方法
公开(公告)号：US08945146B2
公开(公告)日：2015-02-03
申请号：US13279835
申请日：2011-10-24
申请人： H. Allan Steingisser , Don H. Tran , William A. Berthiaume , Brent L. Locsin
发明人： H. Allan Steingisser , Don H. Tran , William A. Berthiaume , Brent L. Locsin
IPC分类号： A61B19/00 , A61N1/372 , A61N1/375 , A61N1/362 , A61N1/05
CPC分类号： A61N1/37205 , A61N1/3622 , A61N1/3756 , A61N2001/0578
摘要： A delivery system assembly includes an outer tube, an inner member, extending within a lumen of the outer tube, and a deflectable shaft, extending within the outer tube lumen and around the inner member; the tube and inner member are longitudinally moveable with respect to the shaft, and a distal end of the inner member is located distal to the shaft within the tube lumen. A medical device can be loaded into the tube lumen, along a distal-most portion of the tube, and contained between the inner member and a distal opening of the tube lumen. Deflecting the shaft orients the distal-most portion for navigation of the assembly, and, when the distal end of the inner member is engaged within the tube lumen, distal movement of the tube, with respect to the shaft, causes similar distal movement of the inner member and the loaded medical device toward an implant site.
摘要翻译：输送系统组件包括在外管的内腔中延伸的外管，内部构件和在外管腔内并围绕内部构件延伸的可偏转的轴; 管和内部构件可以相对于轴纵向移动，并且内部构件的远端位于管腔内远离轴的远侧。医疗装置可以沿着管的最远部分装载到管腔中，并且容纳在内部构件和管腔的远端开口之间。轴的偏转定位用于组件导航的最远部分，并且当内部构件的远端接合在管腔内时，管的相对于轴的远端运动导致相似的远端移动内部构件和装载的医疗装置朝向植入物位置。

8. 发明授权

US08945145B2 Delivery system assemblies for implantable medical devices 有权
标题翻译：可植入医疗器械的输送系统组件
公开(公告)号：US08945145B2
公开(公告)日：2015-02-03
申请号：US13239990
申请日：2011-09-22
申请人： Don H. Tran , William A. Berthiaume , H. Allan Steingisser , Maria Valdovinos , Brent L. Locsin , Suruchi Anand
发明人： Don H. Tran , William A. Berthiaume , H. Allan Steingisser , Maria Valdovinos , Brent L. Locsin , Suruchi Anand
IPC分类号： A61B19/00 , A61B17/34 , A61N1/372 , A61N1/375 , A61N1/362
CPC分类号： A61B17/3468 , A61N1/362 , A61N1/37205 , A61N1/3756
摘要： A delivery system assembly includes an elongate inner member that extends distally through a lumen of an elongate outer tube of the assembly; the outer tube is moveable relative to the inner member between first and second positions to deploy an implantable medical device that is held within the outer tube lumen. The inner member may include a flared distal end that abuts, and preferably conforms to, the proximal end of the device, when the device is held within the outer tube lumen. The assembly further includes a stability sheath that surrounds a limited length of the outer tube, in proximity to the handle, to provide an interface for both an operator, who handles the assembly, and for an introducer sheath that provides passage for the assembly into the venous system, so that movement of the outer tube is not hindered by either during device deployment.
摘要翻译：递送系统组件包括细长的内部构件，其向远侧延伸穿过组件的细长外管的内腔; 外管可在第一和第二位置之间相对于内部构件移动以展开保持在外管内腔内的可植入医疗装置。当装置保持在外管腔内时，内部构件可以包括邻近并且优选地符合装置的近端的扩口远端。组件还包括稳定的护套，其围绕外管的有限长度围绕手柄，以提供用于处理组件的操作者和导引器护套的接口，所述引导器护套为组件提供通道静脉系统，使得在设备部署期间外部管的运动不会受到阻碍。

9. 发明授权

US08989873B2 Intravascular medical device with advancable electrode 有权
标题翻译：具有可推荐电极的血管内医疗器械
公开(公告)号：US08989873B2
公开(公告)日：2015-03-24
申请号：US13187169
申请日：2011-07-20
申请人： Brent L. Locsin
发明人： Brent L. Locsin
IPC分类号： A61N1/00 , A61N1/05 , A61N1/362
CPC分类号： A61N1/0563 , A61N1/362 , A61N1/37205
摘要： Implantable medical devices and methods use an intravascular implantable medical device having an elongated housing module to contain one or more circuitry components. An opening is defined through the elongated housing module. A lead, including at least one electrode, is coupled towards the distal end of the elongated housing module and at least a portion of the at least one electrode is in a stowed position within the opening defined through the elongated housing module during implant of the implantable medical device. The at least one electrode is advanceable from the stowed position to a location distal of the distal end of the elongated housing module.
摘要翻译：植入式医疗装置和方法使用具有细长壳体模块的血管内可植入医疗装置来容纳一个或多个电路部件。通过细长的壳体模块限定开口。包括至少一个电极的引线被联接到细长壳体模块的远端，并且至少一个电极的至少一部分处于通过细长壳体模块限定的开口内的收纳位置，医疗装置。至少一个电极可以从收起位置前进到细长壳体模块的远端的远侧位置。

10. 发明申请

US20130023975A1 INTRAVASCULAR MEDICAL DEVICE WITH ADVANCABLE ELECTRODE 有权
标题翻译：具有高级电极的血管内装置
公开(公告)号：US20130023975A1
公开(公告)日：2013-01-24
申请号：US13187169
申请日：2011-07-20
申请人： Brent L. Locsin
发明人： Brent L. Locsin
IPC分类号： A61N1/05
CPC分类号： A61N1/0563 , A61N1/362 , A61N1/37205
摘要： Implantable medical devices and methods use an intravascular implantable medical device having an elongated housing module to contain one or more circuitry components. An opening is defined through the elongated housing module. A lead, including at least one electrode, is coupled towards the distal end of the elongated housing module and at least a portion of the at least one electrode is in a stowed position within the opening defined through the elongated housing module during implant of the implantable medical device. The at least one electrode is advanceable from the stowed position to a location distal of the distal end of the elongated housing module.
摘要翻译：植入式医疗装置和方法使用具有细长壳体模块的血管内可植入医疗装置来容纳一个或多个电路部件。通过细长的壳体模块限定开口。包括至少一个电极的引线被联接到细长壳体模块的远端，并且至少一个电极的至少一部分处于通过细长壳体模块限定的开口内的收纳位置，医疗装置。至少一个电极可以从收起位置前进到细长壳体模块的远端的远侧位置。

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