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1. 发明授权

US08791700B2 Method of MR (=magnetic resonance) with spatial encoding to generate an image or spectroscopic data 有权
标题翻译：使用空间编码的MR（=磁共振）方法来生成图像或光谱数据
公开(公告)号：US08791700B2
公开(公告)日：2014-07-29
申请号：US13137086
申请日：2011-07-20
申请人： Walter Witschey , Daniel Gallichan , Maxim Zaitsev , Gerrit Schultz , Juergen Hennig
发明人： Walter Witschey , Daniel Gallichan , Maxim Zaitsev , Gerrit Schultz , Juergen Hennig
IPC分类号： G01V3/00 , G01R33/44
CPC分类号： G01R33/445 , G01R33/4833
摘要： A method of MR with spatial encoding to generate an image or spectroscopic data of an object of investigation inside an MR apparatus comprises the steps of (a) selecting a volume of interest within the object of investigation, (b) applying an RF pulse to generate a transverse magnetization within the object of investigation, (c) preparing a nonlinear phase distribution within the object of investigation by application of spatially encoding magnetic fields (SEMs), the SEMs comprising of a nonlinear gradient field or a combination of linear and nonlinear gradient fields, (d) effecting primary spatial encoding through application of SEMs, and (e) recording MR signals originating from the object of investigation. Step (c) or (d) thereby comprises applying a sequence of at least two SEMs, at least one of which contains a nonlinear field gradient and at least two of the SEMs having different field geometries. The sequence of SEMs is applied at a point in time from and including the excitation of the object of interest in step (b) up to and including the recording of the MR signals in step (e), to thereby introduce a temporal shift of the signals arising from spatially different locations within the selected volume of interest, that is to thereby introduce a shift of local spatial frequency components. A sampling window for recording of the respective MR signals is set and signals originating from the volume of interest are recorded in step (e) and undesired signals originating from outside the volume of interest are suppressed.
摘要翻译：一种具有空间编码以在MR装置内产生调查对象的图像或光谱数据的MR的方法包括以下步骤：（a）选择调查对象内的感兴趣体积，（b）施加RF脉冲以产生在研究对象内的横向磁化，（c）通过应用空间编码磁场（SEM）在研究对象内准备非线性相位分布，包括非线性梯度场或线性和非线性梯度场的组合的SEM ，（d）通过应用SEM实现主要空间编码，（e）记录源自调查对象的MR信号。步骤（c）或（d）由此包括施加至少两个SEM序列，其中至少一个包含非线性场梯度和具有不同场几何形状的至少两个SEM。在从步骤（b）中的感兴趣对象的激发到包括步骤（e）中的MR信号的记录的时间点上施加SEM序列，从而引入时间偏移在所选择的感兴趣体积内由空间不同的位置产生的信号，从而引入局部空间频率分量的偏移。设置用于记录各个MR信号的采样窗口，并且在步骤（e）中记录来自感兴趣体积的信号，并且抑制源于感兴趣体积之外的不需要的信号。

2. 发明申请

US20120025822A1 Method of MR (=magnetic resonance) with spatial encoding to generate an image of spectroscopic data 有权
标题翻译：具有空间编码的MR（=磁共振）方法以产生光谱数据的图像
公开(公告)号：US20120025822A1
公开(公告)日：2012-02-02
申请号：US13137086
申请日：2011-07-20
申请人： Walter Witschey , Daniel Gallichan , Maxim Zaitsev , Gerrit Schultz , Juergen Hennig
发明人： Walter Witschey , Daniel Gallichan , Maxim Zaitsev , Gerrit Schultz , Juergen Hennig
IPC分类号： G01R33/48
CPC分类号： G01R33/445 , G01R33/4833
摘要： A method of MR with spatial encoding to generate an image or spectroscopic data of an object of investigation inside an MR apparatus comprises the steps of (a) selecting a volume of interest within the object of investigation, (b) applying an RF pulse to generate a transverse magnetization within the object of investigation, (c) preparing a nonlinear phase distribution within the object of investigation by application of spatially encoding magnetic fields (SEMs), the SEMs comprising of a nonlinear gradient field or a combination of linear and nonlinear gradient fields, (d) effecting primary spatial encoding through application of SEMs, and (e) recording MR signals originating from the object of investigation. Step (c) or (d) thereby comprises applying a sequence of at least two SEMs, at least one of which contains a nonlinear field gradient and at least two of the SEMs having different field geometries. The sequence of SEMs is applied at a point in time from and including the excitation of the object of interest in step (b) up to and including the recording of the MR signals in step (e), to thereby introduce a temporal shift of the signals arising from spatially different locations within the selected volume of interest, that is to thereby introduce a shift of local spatial frequency components. A sampling window for recording of the respective MR signals is set and signals originating from the volume of interest are recorded in step (e) and undesired signals originating from outside the volume of interest are suppressed.
摘要翻译：一种具有空间编码以在MR装置内产生调查对象的图像或光谱数据的MR的方法包括以下步骤：（a）选择调查对象内的感兴趣体积，（b）施加RF脉冲以产生在研究对象内的横向磁化，（c）通过应用空间编码磁场（SEM）在研究对象内准备非线性相位分布，包括非线性梯度场或线性和非线性梯度场的组合的SEM ，（d）通过应用SEM实现主要空间编码，（e）记录源自调查对象的MR信号。步骤（c）或（d）由此包括施加至少两个SEM序列，其中至少一个包含非线性场梯度和具有不同场几何形状的至少两个SEM。在从步骤（b）中的感兴趣对象的激发到包括步骤（e）中的MR信号的记录的时间点上施加SEM序列，从而引入时间偏移在所选择的感兴趣体积内由空间不同的位置产生的信号，从而引入局部空间频率分量的偏移。设置用于记录各个MR信号的采样窗口，并且在步骤（e）中记录来自感兴趣体积的信号，并且抑制源于感兴趣体积之外的不需要的信号。

3. 发明申请

US20120249137A1 Method of dynamically compensating for magnetic field heterogeneity in magnetic resonance imaging 有权
标题翻译：动态补偿磁共振成像磁场异质性的方法
公开(公告)号：US20120249137A1
公开(公告)日：2012-10-04
申请号：US13414737
申请日：2012-03-08
申请人： Walter Witschey , Maxim Zaitsev , Jürgen Hennig , Gerrit Schultz , Daniel Gallichan
发明人： Walter Witschey , Maxim Zaitsev , Jürgen Hennig , Gerrit Schultz , Daniel Gallichan
IPC分类号： G01R33/58
CPC分类号： G01R33/3875
摘要： A method to compensate for the magnetic field heterogeneity inside an object of investigation in a MR device obtains an uncorrected magnetic field distribution of the object and executes an MR sequence with a desired k-space coverage by applying RF pulses to generate a transverse magnetization within the object. MR signal data is recorded, magnetic field shimming parameters are dynamically updated and MR signal data are reconstructed to produce images or localized spectroscopic data. Artifacts in a reconstructed image resulting from an uncorrected magnetic field distribution are suppressed by temporally separating MR signals originating from at least two different sub-volumes within a volume of transverse magnetization by generating a nonlinear phase distribution within the object and by dynamically updating shimming parameters to compensate for the field inhomogeneity distributions within the different sub-volumes in the volume of transverse magnetization.
摘要翻译：用于补偿MR装置内的调查对象内的磁场异质性的方法获得对象的未校正的磁场分布，并通过施加RF脉冲来产生具有期望的k空间覆盖的MR序列，以在其内产生横向磁化目的。记录MR信号数据，动态地更新磁场匀场参数，重建MR信号数据以产生图像或局部光谱数据。通过在对象内生成非线性相位分布，并且通过动态地更新匀场参数来暂时分离来自横向磁化体积内的至少两个不同子体积的MR信号，从而抑制由未校正的磁场分布产生的重构图像中的人造物补偿横向磁化量的不同子体积内的场不均匀性分布。

4. 发明授权

US09377517B2 Method of dynamically compensating for magnetic field heterogeneity in magnetic resonance imaging 有权
标题翻译：动态补偿磁共振成像磁场异质性的方法
公开(公告)号：US09377517B2
公开(公告)日：2016-06-28
申请号：US13414737
申请日：2012-03-08
申请人： Walter Witschey , Maxim Zaitsev , Jürgen Hennig , Gerrit Schultz , Daniel Gallichan
发明人： Walter Witschey , Maxim Zaitsev , Jürgen Hennig , Gerrit Schultz , Daniel Gallichan
IPC分类号： G01R33/58 , G01R33/3875
CPC分类号： G01R33/3875
摘要： A method to compensate for the magnetic field heterogeneity inside an object of investigation in a MR device obtains an uncorrected magnetic field distribution of the object and executes an MR sequence with a desired k-space coverage by applying RF pulses to generate a transverse magnetization within the object. MR signal data is recorded, magnetic field shimming parameters are dynamically updated and MR signal data are reconstructed to produce images or localized spectroscopic data. Artifacts in a reconstructed image resulting from an uncorrected magnetic field distribution are suppressed by temporally separating MR signals originating from at least two different sub-volumes within a volume of transverse magnetization by generating a nonlinear phase distribution within the object and by dynamically updating shimming parameters to compensate for the field inhomogeneity distributions within the different sub-volumes in the volume of transverse magnetization.
摘要翻译：用于补偿MR装置内的调查对象内的磁场异质性的方法获得对象的未校正的磁场分布，并通过施加RF脉冲来产生具有期望的k空间覆盖的MR序列，以在其内产生横向磁化目的。记录MR信号数据，动态地更新磁场匀场参数，重建MR信号数据以产生图像或局部光谱数据。通过在对象内生成非线性相位分布，并且通过动态地更新匀场参数来暂时分离来自横向磁化体积内的至少两个不同子体积的MR信号，从而抑制由未校正的磁场分布产生的重构图像中的人造物补偿横向磁化量的不同子体积内的场不均匀性分布。

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