专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US3341427A Diagnostic preparation and process for the detection of acetylmethylcarbinol 失效
标题翻译：检测乙酰甲基甲醇的诊断准备和方法
公开(公告)号：US3341427A
公开(公告)日：1967-09-12
申请号：US42727265
申请日：1965-01-22
申请人： WARNER LAMBERT PHARMACEUTICAL
发明人： EVANS GEORGE L , HELLER CHARLES I , SCHWARTZ BENJAMIN S
IPC分类号： C12Q1/04
CPC分类号： C12Q1/04 , Y02A50/451 , Y10S435/805 , Y10S435/828 , Y10S435/848 , Y10S435/849 , Y10S435/852
摘要： A test strip for detecting acetylmethylcarbinol (AMC) produced by micro-organisms, and thus for distinguishing such AMC-producing enterobacteria as Aerobacter and Klebsiella from Escherichia coli and E. freundii which do not produce AMC, comprises a strip of bibulous material impregnated with a bacterial growth medium zone, a reagent zone and a hydrophobic barrier zone separating said zones; the medium zone comprises (a) a peptone or polypeptone, (b) dextrose, (c) potassium phosphate, (d) D-glucose and (e) a pyruvic acid salt, and the reagent zone comprises (a) 1-arginine or the monohydrochloride salt thereof and (b) a 1-naphthol sulphonic acid salt. A further barrier zone may be provided at a distance from, and on the other side of, the reagent zone to provide therebetween a migration zone for colour developed in the reagent zone. Sodium and lithium pyruvates and particular sodium and potassium salts of 1-naphthol -5-, -2-, -4- and -3:6- sulphonic acids are specified. The barrier material may comprise lacquer or a (specified) chrome complex. The bibulous material may be filter paper, felt, porous ceramic, or woven or matted glass fibre. In use, the growth medium zone is brought into contact with a suspension of unknown bacteria for 4-5 hours at 37 DEG C., aqueous alkali metal hydroxide is added and the suspension is brought into contact with the reagent zone: a pinkred colour indicates AMC.ALSO:A test strip for detecting acetylmethylcarbinol (AMC) produced by microorganisms comprises a strip of bibulous material impregnated with a bacterial growth medium zone, a reagent zone and a hydrophobic barrier zone separating said zones; the medium zone comprising (a) a peptone or polypeptone, (b) dextrose, (c) potassium phosphate, (d) D-glucose and (e) a pyruvic acid salt, and the reagent zone comprising (a) 1-arginine or the monohydrochloride salt thereof and (b) a 1-naphthol sulphonic acid salt. A further barrier zone may be provided at a distance from and on the other side of the reagent zone to provide therebetween a migration zone for colour developed in the reagent zone. Sodium and lithium pyruvates and particular sodium and potassium salts of 1-naphthol -5-, -2-, -4- and -3:6- sulphonic acids are specified. The barrier material may comprise lacquer or a (specified) chrome complex. The bibulous material may be filter paper, felt, porous ceramic or woven or matted glass fibre. In use, the growth medium zone is brought into contact with a suspension of unknown bacteria for 4-5 hours at 37 DEG C, aqueous alkali metal hydroxide is added and the suspension brought into contact with the reagent zone: a pink-red colour indicates AMC.

2. 发明授权

US3094466A Preparation for typing of staphylococci and process therefor 失效
标题翻译：准备输入葡萄球菌及其过程
公开(公告)号：US3094466A
公开(公告)日：1963-06-18
申请号：US82714059
申请日：1959-07-15
申请人： WARNER LAMBERT PHARMACEUTICAL
发明人： SCHWARTZ BENJAMIN S
IPC分类号： C12Q1/14
CPC分类号： C12Q1/14 , Y10S435/883 , Y10S435/948

3. 发明授权

US3359180A Diagnostic preparation for the detection of acetylmethylcarbinol 失效
标题翻译：检测乙酰甲基甲酚的诊断准备
公开(公告)号：US3359180A
公开(公告)日：1967-12-19
申请号：US62838567
申请日：1967-04-04
申请人： WARNER LAMBERT PHARMACEUTICAL
发明人： EVANS GEORGE L , HELLER CHARLES I , SCHWARTZ BENJAMIN S
IPC分类号： C12Q1/12
CPC分类号： C12Q1/12 , Y10S435/805 , Y10S435/828 , Y10S435/849 , Y10S435/852 , Y10S435/881

4. 发明授权

US3378346A Diagnostic preparation for the detection of indole 失效
标题翻译：用于检测吲哚的诊断准备
公开(公告)号：US3378346A
公开(公告)日：1968-04-16
申请号：US43076365
申请日：1965-02-05
申请人： WARNER LAMBERT PHARMACEUTICAL
发明人： WATSON GLENVILLE R , SCHWARTZ BENJAMIN S
IPC分类号： C07D209/04 , G01N31/22 , G01N33/52
CPC分类号： C07D209/04 , G01N31/22 , G01N33/52 , Y10S435/805 , Y10T436/145555
摘要： A test strip giving a colour reaction with indole comprises a bibulous material which has been impregnated with a solution in an inert volatile solvent of 1-10% p-dimethylaminobenzaldehyde and 10-40% oxalic acid. Specified solvents are methanol and ethanol. A barrier zone may be provided to prevent capillary migration of the reagent, e.g. by applying a lacquer. The bibulous material may be filter paper, felt, porous ceramic strips or woven or matted glass fibres. The absorbency of said materials may be increased by coating with a polymer such as hydroxymethyl cellulose. The test strip may be employed to distinguish indole-producing bacteria such as Escherichia coli from Aerobacter aerogenes or Salmonella typhi. Reference has been directed by the Comptroller to Specification 779,921.
摘要翻译：与吲哚进行着色反应的测试条包括已经用溶液浸渍在1-10％对二甲基氨基苯甲醛和10-40％草酸的惰性挥发性溶剂中的吸水材料。指定的溶剂是甲醇和乙醇。可以提供阻挡区域以防止试剂的毛细管迁移，例如，通过涂漆。吸水材料可以是滤纸，毛毡，多孔陶瓷条或编织或无光玻璃纤维。所述材料的吸收性可以通过用诸如羟甲基纤维素的聚合物涂覆来增加。测试条可以用于区分产生吲哚的细菌如大肠杆菌来自产气杆菌或伤寒沙门氏菌。主计长已经指导了规范779,921。

5. 发明授权

US3331741A Process for the preparation of a soluble bacterial extract 失效
标题翻译：制备可溶性细菌提取物的方法
公开(公告)号：US3331741A
公开(公告)日：1967-07-18
申请号：US41581864
申请日：1964-12-03
申请人： WARNER LAMBERT PHARMACEUTICAL
发明人： JOACHIM AUSCHEL , FOX ALFRED E , EVANS GEORGE L , SCHWARTZ BENJAMIN S
IPC分类号： A61K35/74 , A61K39/04 , A61K45/00 , C12N1/00 , C12P1/00 , C12P1/06
CPC分类号： A61K35/74 , A61K39/04 , A61K45/05 , C12N1/005 , C12P1/00 , C12P1/06 , C12R1/32
摘要： An extract having prophylactic effect against microbial infection is obtained from the cell walls of Mycobacterium Phlei by rupturing the live cells, mixing them with an aqueous solution of urea (10-30%), filtering and, if desired, dialysing and lyophilising the filtrate.
摘要翻译：通过破坏活细胞，将它们与尿素水溶液（10-30％）混合，过滤，如果需要，透析和冻干滤液，从分枝杆菌细胞壁获得具有预防微生物感染作用的提取物。

6. 发明授权

US3172815A Method for preparing reticulo-endo-thelial system stimulant and stimulant thereof 失效
标题翻译：制备网状内皮系统兴奋剂及其兴奋剂的方法
公开(公告)号：US3172815A
公开(公告)日：1965-03-09
申请号：US18969662
申请日：1962-04-24
申请人： WARNER LAMBERT PHARMACEUTICAL
发明人： FOX ALFRED E , SCHWARTZ BENJAMIN S , TURNER FRANK J
IPC分类号： A61K45/00
CPC分类号： A61K45/05 , Y10S435/866

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式