会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明申请
    • NOVEL CANNABIDIOL QUINONE DERIVATIVES
    • 新型CANNABIDIOL喹诺酮衍生物
    • US20170044092A1
    • 2017-02-16
    • US15304810
    • 2014-04-16
    • VIVACELL BIOTECHNOLOGY ESPAÑA S.L.
    • Giovanni APPENDINOMaría Luz BELLIDO CABELLO DE ALBAEduardo MUÑOZ BLANCO
    • C07C225/28C07C69/95
    • C07C225/28C07B2200/07C07C69/95C07C2601/16C07C2602/42
    • The present invention relates to novel cannabidiol quinone derivatives of formula (I) (I) wherein R is the carbon atom of a, linear or branched group, represented by: alkyl, aryl, alkenyl, alkynyl, acyl or alkoxycarbonyl groups; or wherein R is the nitrogen atom of a, linear or branched group represented by: alkylamine, arylamine, alkenylamine or alkynylamine groups. The invention also relates to the use of any of the compounds of formula (I) as medicamentsin therapy, particularly for treating diseases and conditions responsive to PPARg modulation due to their high PPARg agonistic effect lacking electrophilic (Nrf2 activation) and cytotoxic activities. This invention also provides pharmaceutical compositions comprising said compounds and method of treating diseases with said compounds.
    • 本发明涉及式(I)(I)的新型大二酚醌衍生物,其中R是直链或支链基团的碳原子,由烷基,芳基,烯基,炔基,酰基或烷氧基羰基表示; 或其中R为由烷基胺,芳基胺,链烯基胺或炔基胺基团表示的直链或支链基团的氮原子。 本发明还涉及任何式(I)化合物作为治疗药物的用途,特别是用于治疗由于其不具有亲电子(Nrf2活化)和细胞毒活性的高PPARg激动作用而对PPARg调节有反应的疾病和病症。 本发明还提供包含所述化合物的药物组合物和用所述化合物治疗疾病的方法。