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1. 发明授权

US5476005A Method and apparatus for tracing leaks in vivo occurring in an electrode device of an implanted medical apparatus 失效
标题翻译：用于跟踪在植入医疗装置的电极装置中发生的体内泄漏的方法和装置
公开(公告)号：US5476005A
公开(公告)日：1995-12-19
申请号：US271716
申请日：1994-07-07
申请人： Ulf Lindegren , Heinz Neubauer , Hans Strandberg , Hans Schueller
发明人： Ulf Lindegren , Heinz Neubauer , Hans Strandberg , Hans Schueller
IPC分类号： A61N1/05 , G01M3/04 , A61N1/08 , G01M3/20
CPC分类号： G01M3/04 , A61N1/056
摘要： A method and apparatus are disclosed for tracing leaks in vivo which occur in an electrode device, such as a pacemaker or a defibrillator, the electrode device including an electrode cable containing an elongate, flexible conductor having an exterior covered with a layer of insulation and having an interior channel. A leakage tracing device which is simple in structure, and therefore inexpensive to make, and with which one or more leaks in an electrode cable implanted in a patient is/are readily detectable, has a tubular, flexible body within an external diameter smaller than inner diameter of the interior channel of the electrode cable. The tubular body can be inserted into the electrode cable's interior channel all the way to the channel's distal end, and the proximal end of the tubular body is connected to a container for a fluid. The container is capable of producing a gauge pressure which forces fluid through the tubular body into the channel, filling the channel such that a radial fluid pressure, higher than the pressure on the exterior of the electrode cable, develops in the channel. The fluid may be a or contain a contrast agent visible in a fluoroscopic exam, so that any escaping fluid can be detected, thereby indicating the presence of a leak.
摘要翻译：公开了一种用于跟踪在电极装置（例如起搏器或除颤器）中发生的体内泄漏的方法和装置，该电极装置包括电极电缆，该电极电缆包含细长的柔性导体，该电极电缆具有被绝缘层覆盖的外部并具有内部通道。泄漏追踪装置结构简单，因此制造成本低廉，并且电极电缆中植入患者中的一个或多个泄漏易于检测，其具有在小于内部的外径内的管状柔性体电极电缆的内部通道的直径。管状体可以一直插入到电极电缆的内部通道中，直到通道的远端，并且管状体的近端连接到用于流体的容器。容器能够产生表压力，该压力迫使流体通过管状体进入通道，填充通道，使得在通道中形成高于电极电缆外部的压力的径向流体压力。流体可以是或含有在透视检查中可见的造影剂，使得可以检测任何逸出的流体，从而指示存在泄漏。

2. 发明授权

US6129752A Distal end device for an implantable electrical conductor and an electrical conductor equipped with such an end device 有权
标题翻译：用于可植入电导体的远端装置和配备有这种终端装置的电导体
公开(公告)号：US6129752A
公开(公告)日：2000-10-10
申请号：US194236
申请日：1999-06-01
申请人： Heinz Neubauer , Ulf Lindegren
发明人： Heinz Neubauer , Ulf Lindegren
IPC分类号： A61N1/05
CPC分类号： A61N1/0575
摘要： A device for preventing an anchoring element disposed at the distal end of an implantable electrode cable from coming into contact, during introduction of the cable into a body cavity, with a cavity wall and thereby damaging the cavity wall, as a protection element which either projects beyond the distal tip of the helical anchoring element, or has the distal tip of the helical anchoring element embedded therein. The protection element is composed of a porous, resilient, spongy material which is compressible. The protection element has interstices which are at least partially filled with medication, and the protection element is compressible during affixing of the anchoring element in the heart wall, so as to express the medication from the interstices.
摘要翻译： PCT No.PCT / SE97 / 00772 Sec。 371日期1999年6月1日 102（e）日期1999年6月1日PCT提交1997年5月12日PCT公布。公开号WO97 / 45158 PCT 日期1997年12月4日一种用于防止设置在可植入电极电缆的远端处的锚固元件在将电缆引入体腔中时与腔体壁接触，从而损坏腔壁，保护元件突出超过螺旋锚定元件的远端，或者将螺旋锚定元件的远端顶端嵌入其中。保护元件由可压缩的多孔，弹性，海绵状材料组成。保护元件具有至少部分地填充有药物的间隙，并且保护元件在将锚定元件固定在心脏壁中时是可压缩的，以便从间隙表达药物。

3. 发明授权

US5342413A Medical electrode arrangement 失效
标题翻译：医用电极排列
公开(公告)号：US5342413A
公开(公告)日：1994-08-30
申请号：US63555
申请日：1993-05-19
申请人： Jakub Hirschberg , Heinz Neubauer , Nina Gilljam , Staffan Bowald , Ulf Lindegren
发明人： Jakub Hirschberg , Heinz Neubauer , Nina Gilljam , Staffan Bowald , Ulf Lindegren
IPC分类号： A61B5/0408 , A61B5/0478 , A61B5/0492 , A61N1/04 , A61N1/05
CPC分类号： A61N1/056 , A61N1/0565
摘要： An electrode arrangement for in vivo stimulation of tissue with electrical energy has a catheter containing an electrical lead, the lead and the catheter being electrically and mechanically connected to further electrical conductors, arranged in a configuration forming a broad, flat, thin and flexible electrode. The conductors in the electrode are partially exposed and define an electrode surface for delivering electrical energy to adjacent tissue. The electrode arrangement further includes a fixing device, for attaching the electrode to tissue surrounding the tissue to be stimulated. The fixing device includes a fixing element which is mounted on the electrode so as to be movable independently of the electrode, and a stylet which controls movement of the fixing element, the stylet extending through the catheter. The fixing element can be controlled so as to be advanced from a retracted position to a position extending beyond the electrode surface in which the fixing element penetrates the tissue.
摘要翻译：用于用电能体内刺激组织的电极装置具有含有电引线的导管，引线和导管电连接和机械地连接到形成宽，平，薄和柔性电极的构造中的另外的电导体。电极中的导体部分地暴露并且限定用于将电能传递到相邻组织的电极表面。电极装置还包括固定装置，用于将电极附接到要刺激的组织周围的组织。定影装置包括固定元件，该固定元件安装在电极上以能够独立于电极移动;以及探针，该探针控制固定元件的移动，探针延伸穿过导管。可以控制固定元件从缩回位置前进到延伸超过固定元件穿透组织的电极表面的位置。

4. 发明授权

US5575797A Device for explanting a medical electrode device 失效
标题翻译：用于移除医用电极装置的装置
公开(公告)号：US5575797A
公开(公告)日：1996-11-19
申请号：US310875
申请日：1994-09-23
申请人： Heinz Neubauer , Ulf Lindegren , Modesto Guerola
发明人： Heinz Neubauer , Ulf Lindegren , Modesto Guerola
IPC分类号： A61N1/05 , A61B17/22
CPC分类号： A61N1/057 , A61N2001/0578
摘要： A device for explanting an electrode device, particularly an intravascular or intracardiac electrode device having an electrode cable and an electrode head arranged on the cable's distal end, is capable of simply and safely detaching fibrotic matter from the entire surface of the electrode cable and electrode head. The explanting device has a stiff first sleeve, relatively short in relation to the length of the electrode cable, and whose diameter is slightly larger than the external diameter of the electrode cable. One end of the sleeve forms a cutting edge. The first sleeve is connected at its end opposite the cutting edge to a first control body in the form of a stylet with which the first sleeve can be moved along the implanted electrode device. A second sleeve, operable with another stylet, amy additionally be employed, having resilient cutting elements. The second sleeve can be slid over and past the first sleeve, causing its cutting elements to move toward each other for cutting fibrotic tissue around the top of the electrode head.
摘要翻译：用于移除电极装置的装置，特别是具有布置在电缆的远端上的电极电缆和电极头的血管内或心内电极装置能够简单且安全地从电极电缆和电极头的整个表面分离纤维化物质。外植体具有刚性的第一套筒，其相对于电极电缆的长度相对较短，并且其直径略大于电极电缆的外径。套筒的一端形成切削刃。第一套筒在其与切割边缘相对的端部连接到以探针形式的第一控制体，第一套筒可以沿着注入的电极装置移动。可另外使用具有可弹性切割元件的可与另一探针管一起工作的第二套筒。第二套筒可以滑过并穿过第一套筒，导致其切割元件朝向彼此移动，以切割电极头顶部周围的纤维组织。

5. 发明授权

US5423873A Device for stimulating living tissue 失效
标题翻译：刺激活体组织的装置
公开(公告)号：US5423873A
公开(公告)日：1995-06-13
申请号：US111198
申请日：1993-08-24
申请人： Heinz Neubauer , Jakub Hirschberg , Hans Strandberg
发明人： Heinz Neubauer , Jakub Hirschberg , Hans Strandberg
IPC分类号： A61N1/365 , A61N1/372 , A61N1/36
CPC分类号： A61N1/3686 , A61N1/36185 , A61N1/365 , A61N1/372
摘要： A device for stimulating heart tissue contains a stimulation unit connected via a switching device to an electrode system. The number of connecting lines between the stimulation unit and the switching device is minimized by emitting control signals and stimulation pulses from a common pulse signal output socket of the stimulation unit. The switching device contains a signal discriminator which separates the control signals from the stimulation pulses, the control signals then controlling the switching device such that the stimulation pulses are delivered to a specific part of the electrode system.
摘要翻译：用于刺激心脏组织的装置包含经由开关装置连接到电极系统的刺激单元。通过从刺激单元的公共脉冲信号输出插座发出控制信号和刺激脉冲来最小化刺激单元和开关装置之间的连接线的数量。开关装置包含信号鉴别器，其将控制信号与刺激脉冲分离，然后控制信号控制开关装置，使得刺激脉冲被传送到电极系统的特定部分。

6. 发明授权

US5470348A Device for stimulating living tissue 失效
公开(公告)号：US5470348A
公开(公告)日：1995-11-28
申请号：US371824
申请日：1995-01-12
申请人： Heinz Neubauer , Jakub Hirschberg , Hans Strandberg
发明人： Heinz Neubauer , Jakub Hirschberg , Hans Strandberg
IPC分类号： A61N1/365 , A61N1/372 , A61N1/32
CPC分类号： A61N1/3686 , A61N1/36185 , A61N1/365 , A61N1/372
摘要： A device for stimulating heart tissue contains a stimulation unit connected via a switching device to an electrode system. The number of connecting lines between the stimulation unit and the switching device is minimized by emitting control signals and stimulation pulses from a common pulse signal output socket of the stimulation unit. The switching device contains a signal discriminator which separates the control signals from the stimulation pulses, the control signals then controlling the switching device such that the stimulation pulses are delivered to a specific part of the electrode system.

7. 发明授权

US5397341A Defibrillation electrode 失效
标题翻译：除颤电极
公开(公告)号：US5397341A
公开(公告)日：1995-03-14
申请号：US25666
申请日：1993-03-03
申请人： Jakub Hirschberg , Heinz Neubauer , Nina Gilljam , Staffan Bowald
发明人： Jakub Hirschberg , Heinz Neubauer , Nina Gilljam , Staffan Bowald
IPC分类号： A61N1/04 , A61N1/05 , A61N1/39
CPC分类号： A61N1/0563
摘要： A defibrillation electrode has a flexible electrode cable containing at least one elongated, electrically insulated conductors and having an electrode configuration attached at a distal end of the electrode cable. This electrode device configuration a number of elongated, flexible conductors, pre-shaped into an outward bulging configuration, having first ends anchored adjacent to each other at the distal end of the electrode cable, and second ends anchored adjacent to each other at a common connection point. To attain a defibrillation electrode which can be used for intracardial, epicardial and myocardial stimulation of the heart and which can be rapidly introduced into the patient, and applied to the myocardium or pericardium, with no need for major surgery, the conductors are spatially pre-shaped such that the anchored ends at the common connection point are twisted in relation to the anchored ends at the electrode cable's distal end. A device is provided for varying the relative distance between the conductors' anchored ends at the common connection point and the conductors' anchored ends at the distal end of the electrode cable.
摘要翻译：除颤电极具有柔性电极电缆，其包含至少一个细长的电绝缘导体，并且具有连接在电极电缆的远端处的电极构型。该电极装置构造多个细长的柔性导体，预成形为向外凸出的构造，其具有在电极电缆的远端彼此相邻地固定的第一端，并且在公共连接处彼此相邻地固定的第二端点。为了获得可用于心脏心脏，心外膜和心肌刺激心脏并且可以快速引入患者的除颤电极，并且应用于心肌或心包，不需要大手术，导体是空间预处理的，使得在公共连接点处的锚定端部相对于电极电缆的远端处的锚定端扭转。提供了一种装置，用于改变公共连接点处的导体锚固端之间的距离和在电极电缆的远端处的导体锚定端之间的相对距离。

8. 发明授权

US5752915A Device for manipulating a stylet unit for positioning a medical electrode cable in a body cavity 失效
标题翻译：用于操纵用于将医用电极电缆定位在体腔中的探针单元的装置
公开(公告)号：US5752915A
公开(公告)日：1998-05-19
申请号：US732815
申请日：1996-10-15
申请人： Heinz Neubauer , Mats Bostrom
发明人： Heinz Neubauer , Mats Bostrom
IPC分类号： A61M25/01 , A61N1/05 , A61N1/372 , A61B5/04
CPC分类号： A61M25/09041 , A61N1/056 , A61B2018/00946 , A61M25/0152
摘要： A device for manipulating a stylet unit for positioning an electrode cable in a body cavity has an elongate housing, an elongate, axial cavity in the housing and an operating slide, axially movable in relation to the housing, for attachment to a proximal end section of a tubular stylet sleeve in a stylet unit. An elongate coil spring is located in the cavity on the proximal side of the manipulation device. The coil spring forms an inner guide channel to prevent the buckling of the free, proximal end section of the stylet of the stylet unit in the cavity.
摘要翻译：用于操纵用于将电极电缆定位在体腔中的探针单元的装置具有细长壳体，壳体中的细长轴向空腔和可相对于壳体轴向移动的操作滑块，用于附接到壳体的近端部分探针组中的管状探针套管。细长螺旋弹簧位于操纵装置近侧的空腔中。螺旋弹簧形成内部引导通道，以防止腔内单独的探针单元的探针的自由的近端部分的弯曲。

9. 发明授权

US4677990A Endocardial electrode controllable to form selected contours 失效
标题翻译：心内膜电极可控制以形成轮廓
公开(公告)号：US4677990A
公开(公告)日：1987-07-07
申请号：US832677
申请日：1986-02-25
申请人： Heinz Neubauer
发明人： Heinz Neubauer
IPC分类号： A61N1/05
CPC分类号： A61N1/05
摘要： An endocardial electrode controllable to form selected contours has a flexible electrical conductor with an internal axial channel and covered with an insulating sheath. A traction element extends through the channel and is freely moveable therein and is attached to the conductor at a selected location. A portion of the traction element is guided outside of the conductor but within the insulating sheath, and the traction element projects from the channel at a proximal end of the electrode. Tension exerted on the tension element at the proximal end deforms the conductor to a selected contour dependent upon the amount of tension.
摘要翻译：可控制以形成所选轮廓的心内膜电极具有带有内部轴向通道并被绝缘护套覆盖的柔性电导体。牵引元件延伸穿过通道并且在其中自由移动并且在选定位置附接到导体。牵引元件的一部分被引导到导体外部但是在绝缘护套内，并且牵引元件在电极的近端处从通道突出。在近端处施加在张力元件上的张力根据张力的大小将导体变形为选定的轮廓。

10. 发明授权

US5458630A Medical electrode device having a non-gaseous fluid conductor 失效
标题翻译：具有非气态流体导体的医用电极装置
公开(公告)号：US5458630A
公开(公告)日：1995-10-17
申请号：US226337
申请日：1994-04-12
申请人： Kurt Hoegnelid , Heinz Neubauer , Jens Wolf
发明人： Kurt Hoegnelid , Heinz Neubauer , Jens Wolf
IPC分类号： A61B5/0408 , A61B5/0478 , A61B5/0492 , A61N1/05 , A61N1/362 , H01B1/20 , H01B1/22 , H01B1/24 , A61N1/04
CPC分类号： A61N1/05 , H01B1/20 , H01B1/22 , H01B1/24
摘要： A medical electrode device of the type suitable for delivering therapeutic electrical energy in vivo to tissue from an implanted pulse generator, includes a sleeve containing a conductor which is a non-metallic, non-gaseous fluid conductor. The non-gaseous, non-metallic fluid conductor may be a conductive gel or an electrolytic liquid.
摘要翻译：适合于从植入脉冲发生器向组织递送治疗电能的类型的医疗电极装置包括包含非金属非气态流体导体的导体的套管。非气态非金属流体导体可以是导电凝胶或电解液体。

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