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1. 发明申请

US20130240781A1 Ozonolysis Reactions in Liquid CO2 and CO2-Expanded Solvents 有权
标题翻译：液体CO2和二氧化碳膨胀溶剂中的臭氧分解反应
公开(公告)号：US20130240781A1
公开(公告)日：2013-09-19
申请号：US13866414
申请日：2013-04-19
申请人： UNIVERSITY OF KANSAS , ARCHER DANIELS MIDLAND COMPANY
发明人： Bala SUBRAMANIAM , Daryle Busch , Andrew M. Danby , Thomas P. Binder
IPC分类号： C01B13/00
CPC分类号： C01B13/00 , B01D53/1493 , B01D2256/14 , B01D2257/106 , C01B13/10 , C07C37/50 , C07C45/40 , C07C51/34 , C07C67/333 , C07C303/02 , C07D311/78 , C07D323/02 , C07D501/14 , Y02P20/51 , C07C47/02 , C07C47/542 , C07C47/54 , C07C49/185 , C07C47/575 , C07C47/46 , C07C49/04 , C07C53/08 , C07C63/06 , C07C53/126 , C07C69/48 , C07C69/716 , C07C309/08 , C07C39/04
摘要： A method for increasing ozone concentration in a liquid can include: providing a gas having ozone; introducing the ozone-containing gas into a liquid, wherein the liquid and ozone combination has a temperature between about 0.8 and about 1.5 times the critical temperature of ozone; and increasing isothermally, the pressure of the ozone-containing gas above the liquid to about 0.3 to about 5 times the critical pressure of ozone so as to increase the ozone concentration in the liquid. The temperature is expressed in absolute units (Kelvin or Rankin). The method can be used for removing ozone from a gas or for purifying ozone. The liquid having a high ozone concentration can be used for ozonolysis of a substrate.
摘要翻译：提高液体中臭氧浓度的方法可以包括：提供具有臭氧的气体; 将含臭氧的气体引入液体中，其中液体和臭氧组合的温度为臭氧临界温度的约0.8至约1.5倍; 并且等温地增加液体上方的含臭氧气体的压力至臭氧的临界压力的约0.3至约5倍，以增加液体中的臭氧浓度。温度以绝对单位（开尔文或Rankin）表示。该方法可用于从气体中除去臭氧或净化臭氧。具有高臭氧浓度的液体可用于底物的臭氧分解。

2. 发明授权

US09272977B2 Purification of succinic acid from fermentation broth on non-functionalized chromatographic resin 有权
标题翻译：从非官能化色谱树脂上的发酵液中纯化琥珀酸
公开(公告)号：US09272977B2
公开(公告)日：2016-03-01
申请号：US14399028
申请日：2013-04-17
申请人： ARCHER DANIELS MIDLAND COMPANY
发明人： John G. Soper , Mitchell Schultz , Thomas P. Binder
IPC分类号： C07C51/47 , C07C51/42 , B01D15/32 , B01D15/42 , C12P7/46
CPC分类号： C07C51/47 , B01D15/327 , B01D15/426 , C07C51/42 , C12P7/46 , C07C55/10
摘要： A process for purifying a filtered fermentation broth of succinic acid is described. The process involves separating succinic acid from the other organic acids and salts in a raw filtered broth using a non-functionalized chromatographic resin. The operation can be run either as an isocratic elution to yield free succinic acid, or as a gradient or binary elution to produce succinate salt.
摘要翻译：描述了用于纯化过滤的琥珀酸发酵液的方法。该方法包括使用非官能化色谱树脂将琥珀酸与原始过滤的肉汤中的其它有机酸和盐分离。操作可以作为等度洗脱进行，以产生游离的琥珀酸，或者作为梯度或二元洗脱来产生琥珀酸盐。

3. 发明申请

US20150005516A1 PROCESSES FOR MAKING SUGAR AND/OR SUGAR ALCOHOL DEHYDRATION PRODUCTS 审中-公开
标题翻译：制造糖和/或糖酒精脱水产品的方法
公开(公告)号：US20150005516A1
公开(公告)日：2015-01-01
申请号：US14379642
申请日：2013-03-07
申请人： ARCHER DANIELS MIDLAND COMPANY
发明人： Thomas P. Binder , Alexandra Sanborn
IPC分类号： C07D307/46
CPC分类号： C07D307/46 , C07D307/48 , C07D307/50 , C07D493/04 , C07H3/02
摘要： A process is disclosed for making dehydration products from an aqueous sugars solution including pentoses, hexoses or both, for example, an aqueous high fructose corn syrup solution, or from an aqueous solution of one or more of the alcohols of such pentoses and hexoses, for example, from an aqueous sorbitol solution, by an acid-catalyzed dehydration using substituted sulfonic acids solubilized in the aqueous sugars or sugar alcohols solution.
摘要翻译：公开了一种从包含戊糖，己糖或二者的水性糖溶液制备脱水产物的方法，例如水高果糖玉米糖浆溶液，或由一种或多种戊糖和己糖的醇的水溶液，用于例如，从山梨醇水溶液中，通过使用溶解在水性糖或糖醇溶液中的取代磺酸进行酸催化脱水。

4. 发明授权

US09617312B2 Peptide domains that bind small molecules of industrial significance 有权
公开(公告)号：US09617312B2
公开(公告)日：2017-04-11
申请号：US14968406
申请日：2015-12-14
申请人： Iowa State University Research Foundation, Inc. , Archer-Daniels-Midland Company
发明人： Thomas P. Binder , Aragula Gururaj Rao , Yasufumi Yamamoto , Paul D. Hanke
IPC分类号： C07K7/06 , C40B30/06 , C07K14/00 , C07K7/08
CPC分类号： C07K7/06 , C07K5/08 , C07K7/08 , C07K14/00
摘要： Described herein are small peptide domains and consensus sequences that bind small target molecules of industrial importance, e.g., metals such as nickel, β carotene, and isoflavones such as genistein. Also described are fusion proteins containing such binding domains fused to proteins or to peptide domains like GST or CBD that bind other ligands and can be used to immobilize the target binding domain on a support. One class of fusion proteins that is useful in industrial settings are fusions that contain concatemers of target binding domains, which increases the binding equivalents per molecule.

5. 发明授权

US09493393B2 Separation of propionic acid from acrylic acid 有权
标题翻译：丙酸与丙烯酸的分离
公开(公告)号：US09493393B2
公开(公告)日：2016-11-15
申请号：US14906052
申请日：2014-08-22
申请人： ARCHER DANIELS MIDLAND COMPANY
发明人： Mitchell Jo Schultz , Thomas P. Binder , Naveen Sudharsan
IPC分类号： C07C51/47 , C07C67/56 , C07C51/36 , C07C51/377 , C07C67/303 , B01D15/38 , C07B63/00 , B01D15/18 , B01D15/36 , C07C67/317 , C07C45/52 , C07C51/215 , C07C51/25
CPC分类号： C07C51/47 , B01D15/1821 , B01D15/364 , C07B63/00 , C07C45/52 , C07C51/215 , C07C51/252 , C07C51/36 , C07C51/377 , C07C67/303 , C07C67/317 , C07C67/56 , C07C57/04 , C07C53/122 , C07C69/24 , C07C69/54
摘要： A process is provided for chromatographically separating propionic acid from acrylic acid. By means of the inventive process, a reduced propionic acid content acrylic acid product is enabled having a propionic acid content comparable to acrylic acid products from the conventional two stage oxidation of propylene, but wherein the acrylic acid has been produced with a higher propionic acid content by alternative methods.
摘要翻译：提供了丙烯酸与丙烯酸进行色谱分离的方法。通过本发明的方法，使丙酸含量降低的丙酸酸产物的丙酸含量与丙烯的常规二段氧化反应产生的丙烯酸产物相当，但丙烯酸的产生速度高于丙酸通过替代方法。

6. 发明申请

US20160311860A1 PEPTIDE DOMAINS THAT BIND SMALL MOLECULES OF INDUSTRIAL SIGNIFICANCE 有权
公开(公告)号：US20160311860A1
公开(公告)日：2016-10-27
申请号：US14968406
申请日：2015-12-14
申请人： Iowa State University Research Foundation, Inc. , Archer-Daniels-Midland Company
发明人： Thomas P. Binder , Aragula Gururaj Rao , Yasufumi Yamamoto , Paul D. Hanke
IPC分类号： C07K14/00 , C07K7/06 , C07K5/083
CPC分类号： C07K7/06 , C07K5/08 , C07K7/08 , C07K14/00
摘要： Described herein are small peptide domains and consensus sequences that bind small target molecules of industrial importance, e.g., metals such as nickel, β carotene, and isoflavones such as genistein. Also described are fusion proteins containing such binding domains fused to proteins or to peptide domains like GST or CBD that bind other ligands and can be used to immobilize the target binding domain on a support. One class of fusion proteins that is useful in industrial settings are fusions that contain concatemers of target binding domains, which increases the binding equivalents per molecule.

7. 发明授权

US09695217B2 Peptide domains that bind small molecules 有权
公开(公告)号：US09695217B2
公开(公告)日：2017-07-04
申请号：US14968386
申请日：2015-12-14
申请人： Iowa State University Research Foundation, Inc. , Archer-Daniels-Midland Company
发明人： Thomas P. Binder , Aragula Gururaj Rao , Yasufumi Yamamoto , Paul D. Hanke
IPC分类号： C07K7/06 , C40B30/06 , C07K5/08
CPC分类号： C07K7/06 , C07K5/08 , C07K7/08 , C07K14/00
摘要： Described herein are small peptide domains and consensus sequences that bind small target molecules of industrial importance, e.g., metals such as nickel, β carotene, and isoflavones such as genistein. Also described are fusion proteins containing such binding domains fused to proteins or to peptide domains like GST or CBD that bind other ligands and can be used to immobilize the target binding domain on a support. One class of fusion proteins that is useful in industrial settings are fusions that contain concatemers of target binding domains, which increases the binding equivalents per molecule.

8. 发明授权

US09527928B2 Anhydrous corn processing 有权
标题翻译：无水玉米加工
公开(公告)号：US09527928B2
公开(公告)日：2016-12-27
申请号：US14390812
申请日：2013-05-08
申请人： ARCHER DANIELS MIDLAND COMPANY
发明人： Thomas P. Binder
IPC分类号： C08B30/04 , A23D9/02 , C11B1/10 , C11B3/00
CPC分类号： C08B30/044 , A23D9/02 , C11B1/10 , C11B3/008
摘要： Anhydrous methods of fractionating corn grain that do not require the use of water but rather depends on use of organic solvents are described. The methods include contacting whole grain corn flour with a at least one organic solvent selected from the group consisting of a C1-C6 alcohol, ketone, ester or furan to form an admixture having no more than 15% w/w water. The admixture is separated into i) a solids fraction enriched with corn fiber and protein and 2) a liquid organic slurry comprising suspended starch, dissolved corn oil and the organic solvent. The starch is separated from the first organic slurry to obtain a solvent extracted solid starch fraction and a clarified organic solution. The clarified organic solution which contains dissolved oils is retained and may be evaporated to obtain corn oil that can be further refined.
摘要翻译：描述了不需要使用水分离谷物的无水方法，而取决于有机溶剂的使用。所述方法包括使全谷物玉米粉与至少一种选自C1-C6醇，酮，酯或呋喃的有机溶剂接触，形成不超过15％w / w水的混合物。将混合物分离为i）富含玉米纤维和蛋白质的固体级分，以及2）包含悬浮淀粉，溶解的玉米油和有机溶剂的液体有机浆料。将淀粉与第一有机浆料分离，得到溶剂萃取的固体淀粉部分和澄清的有机溶液。含有溶解油的澄清有机溶液被保留并且可以被蒸发以获得可进一步精制的玉米油。

9. 发明授权

US09090579B2 Processes for making sugar and/or sugar alcohol dehydration products 有权
标题翻译：制糖和/或糖醇脱水产物的方法
公开(公告)号：US09090579B2
公开(公告)日：2015-07-28
申请号：US14379642
申请日：2013-03-07
申请人： ARCHER DANIELS MIDLAND COMPANY
发明人： Thomas P. Binder , Alexandra Sanborn
IPC分类号： C07D307/02 , C07D307/46 , C07D493/04 , C07D307/48 , C07D307/50 , C07H3/02
CPC分类号： C07D307/46 , C07D307/48 , C07D307/50 , C07D493/04 , C07H3/02
摘要： A process is disclosed for making dehydration products from an aqueous sugars solution including pentoses, hexoses or both, for example, an aqueous high fructose corn syrup solution, or from an aqueous solution of one or more of the alcohols of such pentoses and hexoses, for example, from an aqueous sorbitol solution, by an acid-catalyzed dehydration using substituted sulfonic acids solubilized in the aqueous sugars or sugar alcohols solution.
摘要翻译：公开了一种从包含戊糖，己糖或二者的水性糖溶液制备脱水产物的方法，例如水高果糖玉米糖浆溶液，或由一种或多种戊糖和己糖的醇的水溶液，用于例如，从山梨糖醇水溶液中，通过使用溶解在水性糖或糖醇溶液中的取代磺酸进行酸催化脱水。

10. 发明申请

US20160376310A1 PEPTIDE DOMAINS THAT BIND SMALL MOLECULES OF INDUSTRIAL SIGNIFICANCE 有权
标题翻译：包含工业意义的小分子的肽区域
公开(公告)号：US20160376310A1
公开(公告)日：2016-12-29
申请号：US14968386
申请日：2015-12-14
申请人： Iowa State University Research Foundation, Inc. , Archer-Daniels-Midland Company
发明人： Thomas P. Binder , Aragula Gururaj Rao , Yasufumi Yamamoto , Paul D. Hanke
IPC分类号： C07K7/06 , C07K5/08
CPC分类号： C07K7/06 , C07K5/08 , C07K7/08 , C07K14/00
摘要： Described herein are small peptide domains and consensus sequences that bind small target molecules of industrial importance, e.g., metals such as nickel, β carotene, and isoflavones such as genistein. Also described are fusion proteins containing such binding domains fused to proteins or to peptide domains like GST or CBD that bind other ligands and can be used to immobilize the target binding domain on a support. One class of fusion proteins that is useful in industrial settings are fusions that contain concatemers of target binding domains, which increases the binding equivalents per molecule.
摘要翻译：本文描述的是结合工业重要的小靶分子的小肽结构域和共有序列，例如金属如镍，β-胡萝卜素和异黄酮如染料木素。还描述了融合蛋白，其含有融合蛋白质或结合其它配体的肽结构域（如GST或CBD）的融合蛋白，并可用于将靶结合结构域固定在载体上。在工业环境中有用的一类融合蛋白是融合靶结合域的融合物，这增加了每个分子的结合当量。

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