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1. 发明授权

US5409947A Cycloheptimidazole derivatives, method of manufacturing the same and therapeutic agents containing these compounds 失效
标题翻译：环己基咪唑衍生物，其制备方法和含有这些化合物的治疗剂
公开(公告)号：US5409947A
公开(公告)日：1995-04-25
申请号：US64446
申请日：1993-05-21
申请人： Tsuyoshi Tomiyama , Akira Tomiyama , Takashi Yanagisawa , Naoto Ueyama , Tomoyuki Kawai , Motoharu Sonegawa , Hiromi Baba , Makoto Haketa
发明人： Tsuyoshi Tomiyama , Akira Tomiyama , Takashi Yanagisawa , Naoto Ueyama , Tomoyuki Kawai , Motoharu Sonegawa , Hiromi Baba , Makoto Haketa
IPC分类号： A61K31/415 , A61K31/4184 , A61P9/00 , A61P9/12 , A61P27/02 , A61P43/00 , C07D235/02 , C07D403/10 , A61K31/41 , C07D257/04
CPC分类号： C07D235/02 , C07D403/10
摘要： New therapeutic agents of cycloheptimidazole derivatives are disclosed, which are represented by the following formula or its alkali-addition salts. ##STR1## (wherein R.sub.1 represents H or isopropyl group; R.sub.2 represents a lower alkyl; R.sub.3 represents a carboxylic acid or tetrazole group. A and A.sub.1 are substituted groups at 4 or 8 position and A.sub.1 is a hydrogen or hydroxy group when A is a hydrogen or A and A.sub.1 is an oxo group. The dotted line "- - - -" is two double bonds or saturated single bonds).These compounds are useful as anti-hypertensive or anti-congestive heart failure agents.
摘要翻译：公开了由下式表示的环庚咪唑衍生物的新治疗剂或其碱加成盐。起床 R2表示低级烷基; R 3表示羧酸或四唑基。 A和A 1为4或8位的取代基，当A为氢或A且A 1为氧代基时，A 1为氢或羟基。虚线“ - - - ”是两个双键或饱和单键）。这些化合物可用作抗高血压或抗充血性心力衰竭剂。

2. 发明授权

US5240944A Cyclic guanidine derivatives, anti-ulceratives and method of manufacturing the same 失效
标题翻译：环状胍衍生物，抗溃疡及其制造方法
公开(公告)号：US5240944A
公开(公告)日：1993-08-31
申请号：US665662
申请日：1991-03-07
申请人： Tsuyoshi Tomiyama , Akira Tomiyama , Tadashi Shirai , Shuuichi Wakabayashi , Tomoyuki Kawai , Naoto Ueyama , Motoharu Sonegawa
发明人： Tsuyoshi Tomiyama , Akira Tomiyama , Tadashi Shirai , Shuuichi Wakabayashi , Tomoyuki Kawai , Naoto Ueyama , Motoharu Sonegawa
IPC分类号： C07D471/14 , C07D487/04 , C07D519/00
CPC分类号： C07D471/14 , C07D487/04
摘要： Derivatives of cyclic guanidine are disclosed, which are represented by the following formula:A--S--Rwherein A is ##STR1## R.sub.1 represent a lower alkyl or substituted phenyl or unsubstituted phenyl group; R.sub.2 is a lower alkyl; R.sub.3 is H or a lower alkyl; R is lower alkyl, alkenyl, alkynyl, alkanoyl, alkenoyl, dialkylaminoalkyl, cyanoalkyl, alkoxycarbonylalkyl, carboxylalkenyl, alkoxycarbonyl, alkoxyalkylcarbonyl, dialkylaminocarbonyl, dialkylaminothiocarbonyl, phenoxyalkylcarbonyl, piperidinoalkyl, pyridine carbonyl, substituted or unsubstituted benzoyl, or substituted or unsubstituted benzyl group. The compounds of the present invention are useful as anti-ulcerative agents.
摘要翻译：公开了由下式表示的环状胍的衍生物：A-S-R其中A为低级烷基或取代的苯基或未取代的苯基; R2是低级烷基; R3是H或低级烷基; R是低级烷基，烯基，炔基，烷酰基，烯酰基，二烷基氨基烷基，氰基烷基，烷氧基羰基烷基，羧基烯基，烷氧基羰基，烷氧基烷基羰基，二烷基氨基羰基，二烷基氨基硫代羰基，苯氧基烷基羰基，哌啶子基烷基，吡啶羰基，取代或未取代的苯甲酰基或取代或未取代的苄基。本发明的化合物可用作抗溃疡剂。

3. 发明授权

US5008282A Cyclic guanidine derivatives, anti-ulceratives and methods of manufacturing the same 失效
标题翻译：环状胍衍生物，抗溃疡及其制造方法
公开(公告)号：US5008282A
公开(公告)日：1991-04-16
申请号：US450264
申请日：1989-12-13
申请人： Tsuyoshi Tomiyama , Akira Tomiyama , Tadashi Shirai , Shuuichi Wakabayashi , Tomoyuki Kawai , Naoto Ueyama , Motoharu Sonegawa
发明人： Tsuyoshi Tomiyama , Akira Tomiyama , Tadashi Shirai , Shuuichi Wakabayashi , Tomoyuki Kawai , Naoto Ueyama , Motoharu Sonegawa
IPC分类号： C07D471/14 , C07D487/04 , C07D519/00
CPC分类号： C07D471/14 , C07D487/04
摘要： Derivatives of cyclic guanidine are disclosed, which are represented by the following formula:A--S--Rwherein A is ##STR1## R.sub.1 represent a lower alkyl or substituted phenyl or unsubstituted phenyl group; R.sub.2 is a lower alkyl; R.sub.3 is H or a lower alkyl; R is lower alkyl, alkenyl, alkynyl, alkanoyl, alkenoyl, dialkylaminoalkyl, cyanoalkyl, alkoxycarbonylalkyl, carboxylalkenyl, alkoxycarbonyl, alkoxyalkylcarbonyl, dialkylaminocarbonyl, dialkylaminothiocarbonyl, phenoxyalkylcarbonyl, piperidinoalkyl, pyridine carbonyl, substituted or unsubstituted benzoyl, or substituted or unsubstituted benzyl group.The compounds of the present invention are useful as anti-ulcerative agents.
摘要翻译：公开了由下式表示的环状胍的衍生物：A-S-R，其中A为低级烷基或取代的苯基或未取代的苯基; R2是低级烷基; R3是H或低级烷基; R是低级烷基，烯基，炔基，烷酰基，烯酰基，二烷基氨基烷基，氰基烷基，烷氧基羰基烷基，羧基烯基，烷氧基羰基，烷氧基烷基羰基，二烷基氨基羰基，二烷基氨基硫代羰基，苯氧基烷基羰基，哌啶子基烷基，吡啶羰基，取代或未取代的苯甲酰基或取代或未取代的苄基。本发明的化合物可用作抗溃疡剂。

4. 发明授权

US4749705A Quinazoline derivative and anti-hypertensive agents 失效
标题翻译：喹唑啉衍生物和抗高血压药
公开(公告)号：US4749705A
公开(公告)日：1988-06-07
申请号：US14370
申请日：1987-02-13
申请人： Tsuyoshi Tomiyama , Tomoyuki Kawai , Yumiko Ichikawa
发明人： Tsuyoshi Tomiyama , Tomoyuki Kawai , Yumiko Ichikawa
IPC分类号： A61K31/505 , A61P9/12 , C07D239/42 , C07D401/04 , C07D491/04 , C07D491/056 , C07D239/84
CPC分类号： C07D401/04 , C07D491/04
摘要： New quinazoline derivatives are disclosed, as represented by the following formula: ##STR1## wherein A is hydrogen atom or lower alkyloxy group; R.sub.4 is hydrogen atom, a lower alkyl, lower alkyloxy or a halogen atom group. Y is hydrogen atom, lower alkyloxy, sulfamoyl or Y and R.sub.4, taken together, are joined to form --O--CH.sub.2 --CH.sub.2 --O--; Z is a 4-oxopiperidino, 4-thioxopiperidino, 4-oximepiperidino, 4-O-loweralkyl-oxime-piperidino, 4-O-(3-lower alkyl-2-hydroxypropyl)-oxime-piperidino, 4-O-(3-lower alkylamino-2-hydroxypropyl)-oxime-piperidino or 4-O-(3-N'-lower alkyl, N'-benzylamino-2-hydroxypropyl)-oxime-piperidino group. These compounds are useful as anti-hypertensive agents.
摘要翻译：公开了新的喹唑啉衍生物，如下式所示：其中A是氢原子或低级烷氧基; R4是氢原子，低级烷基，低级烷氧基或卤原子基团。 Y为氢原子，低级烷氧基，氨磺酰基或Y和R4一起连接形成-O-CH2-CH2-O-; Z是4-氧代哌啶子基，4-硫代哌啶子基，4-氧代哌啶子基，4-O-低级烷基 - 肟 - 哌啶子基，4-O-（3-低级烷基-2-羟丙基） - 肟 - 哌啶子基，4-O-（3 - 低级烷基氨基-2-羟丙基） - 肟 - 哌啶子基或4-O-（3-N'-低级烷基，N'-苄基氨基-2-羟丙基） - 肟 - 哌啶子基。这些化合物可用作抗高血压药。

5. 发明申请

US20070242147A1 Imaging apparatus 失效
标题翻译：成像设备
公开(公告)号：US20070242147A1
公开(公告)日：2007-10-18
申请号：US11730043
申请日：2007-03-29
申请人： Tomoyuki Kawai
发明人： Tomoyuki Kawai
IPC分类号： H04N9/04 , H04N5/335
CPC分类号： H04N5/2352 , H04N5/23212 , H04N5/347 , H04N9/045
摘要： An imaging apparatus, comprising image pickup elements for obtaining image signals and a control device which control read-out of image signals from the image pickup elements, wherein the image pickup elements comprise: light receiving elements which separate incident light into R, G and B colors and photoelectrically convert the incident light separated into the individual colors to obtain image signals including R, G and B signals corresponding to each of the colors; a vertical transfer channel for vertically transferring an image signal read out from the light receiving elements; and a horizontal transfer channel for horizontally transferring the vertically transferred image signal, the control device comprises: a read-out control device which applies a reading pulse to the light receiving elements to control read-out of the image signal from the light receiving elements; a vertical transfer control device which controls vertical transfer of an image signal read out onto the vertical transfer channel; a horizontal transfer control device which controls horizontal transfer of an image signal read out onto the horizontal transfer channel; and a driving control device which controls the read-out control device and the vertical transfer control device so that the R and B signals are each vertically added for a first number of vertical addition pixels and the G signals are vertically added for a second number of vertical addition pixels that is larger than the first number of vertical addition pixels.
摘要翻译：一种成像装置，包括用于获得图像信号的图像拾取元件和控制从图像拾取元件读出图像信号的控制装置，其中图像拾取元件包括：将入射光分离成R，G和B的光接收元件颜色并将分离成各种颜色的入射光光电转换，以获得包括对应于每种颜色的R，G和B信号的图像信号; 用于垂直传送从光接收元件读出的图像信号的垂直传送通道; 以及用于水平传送垂直传送的图像信号的水平传送通道，所述控制装置包括：读出控制装置，其向所述光接收元件施加读取脉冲，以控制从所述光接收元件读出所述图像信号; 垂直传送控制装置，其控制读出到垂直传送通道上的图像信号的垂直传送; 水平传送控制装置，其控制读取到水平传送信道上的图像信号的水平传送; 以及驱动控制装置，其控制读出控制装置和垂直传送控制装置，使得对于第一数量的垂直相加像素，R和B信号各自垂直相加，并且G信号被垂直地添加到第二数量的垂直加法像素大于第一数量的垂直加法像素。

6. 发明申请

US20060173039A1 4-(Substituted aryl)-5-hydroxyisoquinolinone derivative 失效
标题翻译： 4-（取代的芳基）-5-羟基异喹啉酮衍生物
公开(公告)号：US20060173039A1
公开(公告)日：2006-08-03
申请号：US10521565
申请日：2003-07-23
申请人： Futoshi Shiga , Takahiro Kanda , Tetsuya Kimura , Yasuo Takano , Jyunichi Ishiyama , Tomoyuki Kawai , Tsuyoshi Anraku , Kumi Ishikawa
发明人： Futoshi Shiga , Takahiro Kanda , Tetsuya Kimura , Yasuo Takano , Jyunichi Ishiyama , Tomoyuki Kawai , Tsuyoshi Anraku , Kumi Ishikawa
IPC分类号： A61K31/47
CPC分类号： C07D401/10 , A61K31/472 , A61K31/4725 , A61K31/496 , A61K31/5377 , C07D217/24 , C07D409/04
摘要： The invention provides 4-substituted aryl-5-hydroxyisoquinolinone derivatives and their pharmacologically acceptable addition salts with excellent inhibitory effect on poly (ADP-ribose) synthetase. 4-Substituted aryl-5-hydroxyisoquinolinone derivatives, represented by a general formula (1) and their pharmacologically acceptable addition salts.
摘要翻译：本发明提供对聚（ADP-核糖）合成酶具有优异抑制作用的4-取代芳基-5-羟基异喹啉酮衍生物及其药理学上可接受的加成盐。 4-取代的由通式（1）表示的芳基-5-羟基异喹啉酮衍生物及其药理学上可接受的加成盐。

7. 发明授权

US08300131B2 Image pickup device for wide dynamic range at a high frame rate 有权
标题翻译：图像拾取装置，以高帧速率进行宽动态范围
公开(公告)号：US08300131B2
公开(公告)日：2012-10-30
申请号：US12980647
申请日：2010-12-29
申请人： Tomoyuki Kawai , Yasunari Kato
发明人： Tomoyuki Kawai , Yasunari Kato
IPC分类号： H04N5/335 , H04N3/14
CPC分类号： G03B7/091 , H04N5/35554 , H04N5/372 , H04N9/045
摘要： An image pickup device includes an image sensing device and a driving unit. The image sensing device includes a first pixel group and a second pixel group. The first pixel group includes a plurality of pixels arranged as a two-dimensional array in a semiconductor substrate surface portion that receives incidence light from a subject. The second pixel group includes a plurality of pixels arranged as a two-dimensional array in the semiconductor substrate surface portion in an area overlapping the first pixel group while the pixels in the first pixel group do not disposed in the same positions as the pixels in the second pixel group. The driving unit outputs a picked-up image signal of one frame from the first pixel group exposed over one vertical synchronizing time period for each vertical synchronizing signal.
摘要翻译：图像拾取装置包括图像感测装置和驱动单元。图像感测装置包括第一像素组和第二像素组。第一像素组包括在接收来自被摄体的入射光的半导体衬底表面部分中排列为二维阵列的多个像素。第二像素组包括在与第一像素组重叠的区域中的半导体衬底表面部分中排列为二维阵列的多个像素，而第一像素组中的像素不位于与第一像素组中的像素相同的位置第二像素组。驱动单元从针对每个垂直同步信号的一个垂直同步时间周期暴露的第一像素组输出一帧的拾取图像信号。

8. 发明授权

US08081220B2 Digital still camera and method of controlling image combination 有权
标题翻译：数码相机及图像组合控制方法
公开(公告)号：US08081220B2
公开(公告)日：2011-12-20
申请号：US12167019
申请日：2008-07-02
申请人： Tomoyuki Kawai
发明人： Tomoyuki Kawai
IPC分类号： H04N5/228
CPC分类号： H04N5/2353 , H04N5/23248 , H04N5/2327 , H04N5/2356 , H04N5/243
摘要： A solid-state electronic image sensing device senses the image of a subject repeatedly for an exposure time over which camera shake is thought not to occur, and repeatedly outputs image data representing the image of the subject. A combining device generates one frame of a combined image obtained by combining the image of the subject represented by image data that has been output from the solid-state electronic image sensing device with the image of the subject represented by image data that was output from the solid-state electronic image sensing device by an immediately preceding image sensing operation, in such a manner that the images of the subject coincide. A combining control device controls the combining device so as to repeatedly execute processing for generating one frame of a combined image updated by combining the combined image, which is the result of combination by the combining device, with the image of the subject represented by image data that has been output from the solid-state electronic image sensing device, in such a manner that the images coincide.
摘要翻译：固态电子图像感测装置在相机抖动被认为不发生的曝光时间反复感测对象的图像，并且重复地输出表示被摄体的图像的图像数据。组合装置生成通过将从固态电子图像感测装置输出的图像数据所表示的被摄体的图像与由从固态电子图像感测装置输出的图像数据表示的被摄体的图像组合而获得的组合图像的一帧固体电子图像感测装置通过紧邻的图像感测操作，使得对象的图像一致。组合控制装置控制组合装置，以便通过将作为组合装置的组合结果的组合图像与由图像数据表示的对象的图像组合来重复执行用于生成组合图像的一帧的处理已经从固态电子图像感测装置输出，使得图像重合。

9. 发明申请

US20090009614A1 DIGITAL STILL CAMERA AND METHOD OF CONTROLLING OPERATION OF SAME 有权
标题翻译：数字静态摄像机及其控制方法
公开(公告)号：US20090009614A1
公开(公告)日：2009-01-08
申请号：US12167019
申请日：2008-07-02
申请人： Tomoyuki Kawai
发明人： Tomoyuki Kawai
IPC分类号： H04N5/228
CPC分类号： H04N5/2353 , H04N5/23248 , H04N5/2327 , H04N5/2356 , H04N5/243
摘要： A solid-state electronic image sensing device senses the image of a subject repeatedly for an exposure time over which camera shake is thought not to occur, and repeatedly outputs image data representing the image of the subject. A combining device generates one frame of a combined image obtained by combining the image of the subject represented by image data that has been output from the solid-state electronic image sensing device with the image of the subject represented by image data that was output from the solid-state electronic image sensing device by an immediately preceding image sensing operation, in such a manner that the images of the subject coincide. A combining control device controls the combining device so as to repeatedly execute processing for generating one frame of a combined image updated by combining the combined image, which is the result of combination by the combining device, with the image of the subject represented by image data that has been output from the solid-state electronic image sensing device, in such a manner that the images coincide.
摘要翻译：固态电子图像感测装置在相机抖动被认为不发生的曝光时间反复感测对象的图像，并且重复地输出表示被摄体的图像的图像数据。组合装置生成通过将从固态电子图像感测装置输出的图像数据所表示的被摄体的图像与由从固态电子图像感测装置输出的图像数据表示的被摄体的图像组合而获得的组合图像的一帧固体电子图像感测装置通过紧邻的图像感测操作，使得对象的图像一致。组合控制装置控制组合装置，以便通过将作为组合装置的组合结果的组合图像与由图像数据表示的对象的图像组合来重复执行用于生成组合图像的一帧的处理已经从固态电子图像感测装置输出，使得图像重合。

10. 发明授权

US06529826B2 Navigation apparatus and communication base station, and navigation system and navigation method using same 失效
公开(公告)号：US06529826B2
公开(公告)日：2003-03-04
申请号：US09995653
申请日：2001-11-29
申请人： Tomoyuki Kawai , Kengo Maeda
发明人： Tomoyuki Kawai , Kengo Maeda
IPC分类号： G01C2100
CPC分类号： G01C21/3629 , G01C21/3605 , G01C21/3679
摘要： A navigation apparatus for guiding a moving body from a current location to a destination using a communication base station includes a current location detection device for detecting a current location of the moving body and outputting current location information; a sending device for sending the current location information and destination information to the communication base station; a receiving device for receiving guiding information, which is required to guide the moving body from the current location to the destination and includes information representing a location of a guiding point and a navigation message corresponding to the guiding point, from the communication base station; a memory device for storing the guiding information; and a voice processing device for outputting the navigation message in voice format, based on the current location information and the information representing the location of the guiding point which is included in the guiding information.

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