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    • 2. 发明申请
    • BLOOD COAGULATION ANALYZER
    • 血液凝聚分析仪
    • US20120282139A1
    • 2012-11-08
    • US13509661
    • 2010-11-19
    • Akihisa MakinoTomonori MimuraTerumi TamuraSakuichiro Adachi
    • Akihisa MakinoTomonori MimuraTerumi TamuraSakuichiro Adachi
    • G01N21/75
    • G01N21/51G01N21/532G01N21/82G01N33/18G01N33/1826G01N33/4905G01N33/86G01N2021/4711G01N2021/825
    • A blood coagulation analyzer that realizes both securement of a wide dynamic range and enhancement of sensitivity in blood coagulation analysis by selecting an appropriate angle of detection depending on the intensity of scattered light from each specimen without causing complexity of the analyzer. The analyzer has a reaction container. A storage unit is provided which takes in and stores multiple pieces of chronological light intensity variation data acquired from detectors arranged around a reaction container. A judgment unit selects light intensity variation data to be used for calculation of a blood coagulation time from the multiple pieces of light intensity variation data stored in the storage unit based on the amount of light intensity variation. A calculation unit calculates the blood coagulation time from the light intensity variation data selected by the judgment unit.
    • 一种血液凝固分析仪,其通过根据来自每个样本的散射光的强度选择适当的检测角度,而不会导致分析仪的复杂性,实现了动态范围的确定和凝固分析中的灵敏度的提高。 分析仪具有反应容器。 提供一种存储单元,其存储并存储从设置在反应容器周围的检测器获取的多个按时间顺序的光强度变化数据。 判断单元基于光强度变化量从存储在存储单元中的多个光强度变化数据中选择要用于计算凝血时间的光强度变化数据。 计算单元根据由判断单元选择的光强度变化数据计算凝血时间。
    • 4. 发明授权
    • Automatic analyzer
    • 自动分析仪
    • US09080972B2
    • 2015-07-14
    • US13979668
    • 2012-01-10
    • Akihisa MakinoSakuichiro Adachi
    • Akihisa MakinoSakuichiro Adachi
    • G01N21/53G01N21/49G01N21/51G01N35/00
    • G01N21/49G01N21/51G01N35/00693G01N2201/0415G01N2201/1211
    • The scattered light from the measurement target substance passes through a light receiving window, and is received by a detector for +θ scattered light and a detector for −θ scattered light which are arranged symmetrically to each other across an optical axis at an equal angle or an equal interval in a vertical direction. A light source is fixed by a light-source holder (that is a base member on which the light source is arranged), and the detectors are arranged on and fixed to a detector holder (that is a base member on which the detectors are arranged). In this manner, drift of the light quantity data caused by the thermal deformation of the optical system can be corrected by comparing values of the light quantity data of the detectors.
    • 来自测量对象物质的散射光通过光接收窗口,并被检测器接收+ 散射光和检测器 - &thetas; 散射光在垂直方向上以等角度或等间隔的光轴彼此对称地布置。 光源由光源保持器(即配置有光源的基底部件)固定,检测器被配置在检测器支架(作为检测器布置在其上的基底部件)上并固定 )。 以这种方式,可以通过比较检测器的光量数据的值来校正由光学系统的热变形引起的光量数据的漂移。
    • 5. 发明授权
    • Sample analyzing device
    • 样品分析仪
    • US08709345B2
    • 2014-04-29
    • US13147809
    • 2010-03-01
    • Sakuichiro AdachiAkihisa Makino
    • Sakuichiro AdachiAkihisa Makino
    • G01N35/02G01N21/27G01N21/25
    • G01N35/025G01N21/253G01N21/272G01N21/274G01N2201/127Y10T436/113332Y10T436/114998
    • To reduce measurement time, it may be considered to quicken reaction or speed up analytic determination. In existing analyzing devices, photometry is performed, typically, about every 15 seconds, so that it has not been possible to secure satisfactory reproducibility. Namely, reducing the measurement time and securing reproducibility have not been compatible. It has therefore been desired to increase the number of times of measurements performed in a short period of time. A cell disk is controlled to stop at a position for photometry during the time after a sample and a reagent are mixed and before measurement is finished and, while the cell disk is stopped, photometry is performed once or plural times thereby increasing the total number of times of measurements.
    • 为了减少测量时间,可以考虑加快反应或加速分析测定。 在现有的分析装置中,通常每隔15秒进行测光,因此不可能确保令人满意的再现性。 也就是说,减少测量时间和确保再现性不兼容。 因此,期望在短时间内增加测量次数。 控制细胞盘在样品和试剂混合之后并在测量结束之前的时间点停止在测光位置,并且在细胞盘停止时,测光一次或多次,从而增加总数 测量次数。
    • 6. 发明申请
    • AUTOMATIC ANALYSIS APPARATUS
    • 自动分析仪
    • US20120039748A1
    • 2012-02-16
    • US13202337
    • 2010-02-24
    • Tomonori MimuraAkihisa MakinoSakuichiro Adachi
    • Tomonori MimuraAkihisa MakinoSakuichiro Adachi
    • G01N33/00
    • G01N35/025G01N2035/0455
    • An automatic analysis apparatus capable of testing a plurality of items with high accuracy and at low cost without increasing the size of the apparatus is provided. An automatic analysis apparatus 1 having test mechanisms for a plurality of items including a photometric mechanism 70 and flow analysis mechanisms 40a and 40b is provided with a common disk (disk for reaction and pretreatment) 20. In the common disk 20, fixed containers 21 fixed to the common disk 20 and detachably-provided disposable containers 22 are disposed. Therefore, while achieving the downsizing of the apparatus, the containers to be used can be selected in accordance with the test items in such a manner that the fixed containers 21 are used as high-accuracy containers to be cleaned and reused and the disposable containers 22 are used as low-cost disposable containers.
    • 提供了一种能够在不增加设备尺寸的情况下以高精度和低成本测试多个项目的自动分析装置。 具有包括测光机构70和流量分析机构40a,40b的多个项目的测试机构的自动分析装置1设置有公共盘(反应和预处理盘)20。在普通盘20中,固定容器21固定 配置在普通盘20上,可拆卸地设置一次性容器22。 因此,在实现装置的小型化的同时,可以根据试验项目来选择要使用的容器,使得固定容器21用作待清洁和重复使用的高精度容器,并且一次性容器22 被用作低成本的一次性容器。
    • 8. 发明申请
    • AUTOMATIC ANALYZER
    • 自动分析仪
    • US20130301048A1
    • 2013-11-14
    • US13979668
    • 2012-01-10
    • Akihisa MakinoSakuichiro Adachi
    • Akihisa MakinoSakuichiro Adachi
    • G01N21/49
    • G01N21/49G01N21/51G01N35/00693G01N2201/0415G01N2201/1211
    • The scattered light from the measurement target substance passes through a light receiving window, and is received by a detector for +θ scattered light and a detector for −θ scattered light which are arranged symmetrically to each other across an optical axis at an equal angle or an equal interval in a vertical direction. A light source is fixed by a light-source holder (that is a base member on which the light source is arranged), and the detectors are arranged on and fixed to a detector holder (that is a base member on which the detectors are arranged). In this manner, drift of the light quantity data caused by the thermal deformation of the optical system can be corrected by comparing values of the light quantity data of the detectors.
    • 来自测量对象物质的散射光通过光接收窗,并且由用于+θ散射光的检测器和用于散射光的检测器接收,所述检测器以相等的角度跨越光轴彼此对称布置,或 在垂直方向上相等的间隔。 光源由光源保持器(即配置有光源的基底部件)固定,检测器被配置在检测器支架(作为检测器布置在其上的基底部件)上并固定 )。 以这种方式,可以通过比较检测器的光量数据的值来校正由光学系统的热变形引起的光量数据的漂移。
    • 10. 发明申请
    • AUTOMATIC ANALYSIS APPARATUS
    • 自动分析仪
    • US20120048036A1
    • 2012-03-01
    • US13262671
    • 2010-04-08
    • Tomonori MimuraAkihisa MakinoSakuichiro Adachi
    • Tomonori MimuraAkihisa MakinoSakuichiro Adachi
    • G01N1/22
    • G01N35/025G01N35/0092
    • An automatic analysis apparatus that is capable of aligning the timing of sample dispensing and efficiently carrying out tests of a plurality of items. An intermediate disk (disk) is set so that an A-cycle for carrying out an operation for pretreatment and B-cycles for carrying out operations for dispensing a sample to a reaction disk and a flow analysis mechanism serving as test mechanisms are combined to use n-units of the B-cycles as a dispensing operation cycle time period of the sample. Therefore, the timing of sampling can be efficiently aligned so that the test of an item having a short analysis cycle can be carried out during the test of an item having a long analysis cycle, and so that the tests of an item having a large number of requests can be carried out during the test of the item having a small number of requests.
    • 一种自动分析装置,其能够对准样品分配的定时并且有效地进行多个项目的测试。 中间盘(盘)被设置为使得用于执行用于预处理的操作的A循环和用于将用于将样品分配到反应盘的操作的B循环和用作测试机构的流量分析机构组合使用 B个循环的n个单位作为样品的分配操作循环时间段。 因此,可以有效地对准采样的定时,使得在具有长分析周期的项目的测试期间可以执行具有短分析周期的项目的测试,并且使得具有大数量的项目的测试 可以在具有少量请求的项目的测试期间执行请求。