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1. 发明申请

US20120282139A1 BLOOD COAGULATION ANALYZER 有权
标题翻译：血液凝聚分析仪
公开(公告)号：US20120282139A1
公开(公告)日：2012-11-08
申请号：US13509661
申请日：2010-11-19
申请人： Akihisa Makino , Tomonori Mimura , Terumi Tamura , Sakuichiro Adachi
发明人： Akihisa Makino , Tomonori Mimura , Terumi Tamura , Sakuichiro Adachi
IPC分类号： G01N21/75
CPC分类号： G01N21/51 , G01N21/532 , G01N21/82 , G01N33/18 , G01N33/1826 , G01N33/4905 , G01N33/86 , G01N2021/4711 , G01N2021/825
摘要： A blood coagulation analyzer that realizes both securement of a wide dynamic range and enhancement of sensitivity in blood coagulation analysis by selecting an appropriate angle of detection depending on the intensity of scattered light from each specimen without causing complexity of the analyzer. The analyzer has a reaction container. A storage unit is provided which takes in and stores multiple pieces of chronological light intensity variation data acquired from detectors arranged around a reaction container. A judgment unit selects light intensity variation data to be used for calculation of a blood coagulation time from the multiple pieces of light intensity variation data stored in the storage unit based on the amount of light intensity variation. A calculation unit calculates the blood coagulation time from the light intensity variation data selected by the judgment unit.
摘要翻译：一种血液凝固分析仪，其通过根据来自每个样本的散射光的强度选择适当的检测角度，而不会导致分析仪的复杂性，实现了动态范围的确定和凝固分析中的灵敏度的提高。分析仪具有反应容器。提供一种存储单元，其存储并存储从设置在反应容器周围的检测器获取的多个按时间顺序的光强度变化数据。判断单元基于光强度变化量从存储在存储单元中的多个光强度变化数据中选择要用于计算凝血时间的光强度变化数据。计算单元根据由判断单元选择的光强度变化数据计算凝血时间。

2. 发明授权

US09395298B2 Blood coagulation analyzer 有权
标题翻译：凝血分析仪
公开(公告)号：US09395298B2
公开(公告)日：2016-07-19
申请号：US13509661
申请日：2010-11-19
申请人： Akihisa Makino , Tomonori Mimura , Terumi Tamura , Sakuichiro Adachi
发明人： Akihisa Makino , Tomonori Mimura , Terumi Tamura , Sakuichiro Adachi
IPC分类号： G01N33/50 , G01N21/00 , G01N21/51 , G01N33/49 , G01N33/86 , G01N21/53 , G01N21/82 , G01N33/18
CPC分类号： G01N21/51 , G01N21/532 , G01N21/82 , G01N33/18 , G01N33/1826 , G01N33/4905 , G01N33/86 , G01N2021/4711 , G01N2021/825
摘要： A blood coagulation analyzer that realizes both securement of a wide dynamic range and enhancement of sensitivity in blood coagulation analysis by selecting an appropriate angle of detection depending on the intensity of scattered light from each specimen without causing complexity of the analyzer. The analyzer has a reaction container. A storage unit is provided which takes in and stores multiple pieces of chronological light intensity variation data acquired from detectors arranged around a reaction container. A judgment unit selects light intensity variation data to be used for calculation of a blood coagulation time from the multiple pieces of light intensity variation data stored in the storage unit based on the amount of light intensity variation. A calculation unit calculates the blood coagulation time from the light intensity variation data selected by the judgment unit.
摘要翻译：一种血液凝固分析仪，其通过根据来自每个样本的散射光的强度选择适当的检测角度，而不会导致分析仪的复杂性，实现了动态范围的确定和凝固分析中的灵敏度的提高。分析仪具有反应容器。提供一种存储单元，其存储并存储从设置在反应容器周围的检测器获取的多个按时间顺序的光强度变化数据。判断单元基于光强度变化量从存储在存储单元中的多个光强度变化数据中选择要用于计算凝血时间的光强度变化数据。计算单元根据由判断单元选择的光强度变化数据计算凝血时间。

3. 发明授权

US08858882B2 Automatic analysis device 有权
标题翻译：自动分析装置
公开(公告)号：US08858882B2
公开(公告)日：2014-10-14
申请号：US13577963
申请日：2011-02-24
申请人： Sakuichiro Adachi , Terumi Tamura , Hajime Yamazaki , Akihisa Makino , Takeshi Yogi
发明人： Sakuichiro Adachi , Terumi Tamura , Hajime Yamazaki , Akihisa Makino , Takeshi Yogi
IPC分类号： G01N21/75 , G01N21/51 , G01N35/02 , G01N21/53
CPC分类号： G01N21/51 , G01N21/532 , G01N35/025 , Y10T436/113332
摘要： There is provided a data processing method that reduces influences of air bubbles and dirt while maintaining changes in light amounts. Two scattering light photoreceivers are disposed in the forward direction. A photoreceiver 33a closer to the optical axis is taken to be a main angle photoreceiver, and a photoreceiver 33b further from the optical axis is taken to be a sub-angle photoreceiver. Noise is estimated based on the reaction process data of the sub-angle photoreceiver, and noise is reduced by subtracting the estimated noise from the reaction process data of the main angle photoreceiver.
摘要翻译：提供了一种在保持光量变化的同时减少气泡和污物的影响的数据处理方法。两个散射光接收器沿向前方向设置。靠近光轴的光接收器33a被认为是主角光接收器，并且从光轴进一步的光接收器33b被认为是副角光接收器。基于副角光接收器的反应过程数据估计噪声，并且通过从主角光接收器的反应过程数据中减去估计的噪声来降低噪声。

4. 发明申请

US20120315190A1 AUTOMATIC ANALYSIS DEVICE 有权
标题翻译：自动分析装置
公开(公告)号：US20120315190A1
公开(公告)日：2012-12-13
申请号：US13577963
申请日：2011-02-24
申请人： Sakuichiro Adachi , Terumi Tamura , Hajime Yamazaki , Akihisa Makino , Takeshi Yogi
发明人： Sakuichiro Adachi , Terumi Tamura , Hajime Yamazaki , Akihisa Makino , Takeshi Yogi
IPC分类号： G01N21/75
CPC分类号： G01N21/51 , G01N21/532 , G01N35/025 , Y10T436/113332
摘要： There is provided a data processing method that reduces influences of air bubbles and dirt while maintaining changes in light amounts. Two scattering light photoreceivers are disposed in the forward direction. A photoreceiver 33a closer to the optical axis is taken to be a main angle photoreceiver, and a photoreceiver 33b further from the optical axis is taken to be a sub-angle photoreceiver. Noise is estimated based on the reaction process data of the sub-angle photoreceiver, and noise is reduced by subtracting the estimated noise from the reaction process data of the main angle photoreceiver.
摘要翻译：提供了一种在保持光量变化的同时减少气泡和污物的影响的数据处理方法。两个散射光接收器沿向前方向设置。靠近光轴的光接收器33a被认为是主角光接收器，并且从光轴进一步的光接收器33b被认为是副角光接收器。基于副角光接收器的反应过程数据估计噪声，并且通过从主角光接收器的反应过程数据中减去估计的噪声来降低噪声。

5. 发明申请

US20090229954A1 SPECIMEN TRANSPORT SYSTEM 审中-公开
标题翻译：样本运输系统
公开(公告)号：US20090229954A1
公开(公告)日：2009-09-17
申请号：US12357674
申请日：2009-01-22
申请人： Kazuhiro NODA , Terumi Tamura , Jyunichi Ooizumi
发明人： Kazuhiro NODA , Terumi Tamura , Jyunichi Ooizumi
IPC分类号： B65G21/14 , B65G23/44
CPC分类号： B65G21/14
摘要： An object of the present invention is to provide a specimen transport system that can easily be installed without requiring much time and regardless of various transport distances and also is inexpensive. In the present invention, the distance between apparatuses, which had been difficult to be met by a specimen transport line when a specimen transport system is built, can easily be met by providing a structure in which a conveyor belt is formed in an endless loop and the shape of the loop of the conveyor belt is changed according to the length of a rack transport surface (rack transport surface length), and flexibility for apparatus and system installation and space efficiency can be enhanced, enabling substantial reduction of time and costs in building a specimen transport system.
摘要翻译：本发明的目的是提供一种能够容易地安装而不需要大量时间并且不管各种运输距离如何，并且也便宜的检体输送系统。在本发明中，通过提供将输送带形成为无端环的结构，能够容易地满足试样输送线在构成检体输送系统时难以满足的装置之间的距离，传送带环的形状根据机架传送面的长度（机架传送面长度）而改变，可以提高设备和系统安装的灵活性，提高空间效率，大大减少建筑物的时间和成本标本运输系统。

6. 发明授权

US08952324B2 Mass analyzing apparatus, analyzing method and calibration sample 有权
标题翻译：质量分析仪器，分析方法和校准样品
公开(公告)号：US08952324B2
公开(公告)日：2015-02-10
申请号：US13978445
申请日：2011-12-27
申请人： Midori Sasaki , Terumi Tamura , Shinya Ito , Makoto Nogami
发明人： Midori Sasaki , Terumi Tamura , Shinya Ito , Makoto Nogami
IPC分类号： H01J49/26 , H01J49/00
CPC分类号： H01J49/0009
摘要： The mass analyzing apparatus of the present invention can achieve the speed-up and simplification of the formation of a calibration curve for quantifying an analysis object in a mass analyzing apparatus. The mass analyzing apparatus is provided with: a sample storage-dilution unit 1 for storing samples of the analysis object including a quantitative calibrator in which, with respect to one analysis object to be quantified, two or more kinds of compounds selected from the analysis object, a plurality of stable isotope compounds of the analysis object and a plurality of analogue compounds of the analysis object are mixed at respectively different concentrations; an ionizing unit 5 for ionizing a sample; a mass analyzing unit 6 for analyzing the ionized sample; and a data processing unit 7 in which, based on results of analysis of the quantitative calibrator carried out by the mass analyzing unit 6, two or more concentrations are measured, and the analysis object is quantified based on information of the measurement.
摘要翻译：本发明的质量分析装置可以实现加速和简化在质量分析装置中对分析对象进行定量的校准曲线的形成。质量分析装置具备：样本存储稀释单元1，用于存储包括定量校准器的分析对象的样本，其中对于要定量的一个分析对象，选自分析对象中的两种或更多种化合物分析对象的多个稳定的同位素化合物和分析对象的多个类似化合物分别以不同的浓度混合，用于电离样品的电离单元5; 用于分析电离样品的质量分析单元6; 以及数据处理单元7，其中，基于由质量分析单元6执行的定量校准器的分析结果，测量两个或更多个浓度，并且基于测量的信息量化分析对象。

7. 发明授权

US07300628B2 Automatic analyzing apparatus 有权
公开(公告)号：US07300628B2
公开(公告)日：2007-11-27
申请号：US10445918
申请日：2003-05-28
申请人： Keiko Nogawa , Michiaki Sekiguchi , Hiroshi Watanabe , Hiroaki Ishizawa , Terumi Tamura
发明人： Keiko Nogawa , Michiaki Sekiguchi , Hiroshi Watanabe , Hiroaki Ishizawa , Terumi Tamura
IPC分类号： B32B5/02 , G01N35/02 , B32B27/12
CPC分类号： G01N35/026 , G01N2035/0415 , G01N2035/0472 , Y10T436/11 , Y10T436/110833 , Y10T436/113332 , Y10T436/114165 , Y10T436/115831
摘要： An automatic analyzing apparatus has an analysis section including an immunity analysis unit and a biochemical componential analysis unit. A sample rack which has undergone the immunity componential analysis is horizontally fed by a rack feeding mechanism from a position confronting the inlet of a rack stationing section to a position near the outlet of the rack stationing section, so that the sample rack is directly moved to a return line, while skipping over the rack stationing section, so as to be efficiently returned to the analysis section and subjected to a subsequent biochemical analysis. A sample rack that needs reexamination by an identical analysis unit is also returned in the same efficient way.

8. 发明授权

US10302641B2 Automatic analysis device 有权
公开(公告)号：US10302641B2
公开(公告)日：2019-05-28
申请号：US14766377
申请日：2014-01-23
申请人： Shunichiro Nobuki , Muneo Maeshima , Terumi Tamura , Kenta Imai
发明人： Shunichiro Nobuki , Muneo Maeshima , Terumi Tamura , Kenta Imai
IPC分类号： G01N21/05 , G01N21/69 , G01N21/76 , G01N27/74 , G01N35/00 , G01N33/543 , G01N33/561
摘要： An analyzing device of the present invention is provided with a flow chamber that a fluid including magnetic particles associated with a labeling substance flows from a fluid inlet to a fluid outlet, magnetic trap means to apply a magnetic field for trapping the magnetic particles to the fluid in the flow chamber, a working electrode and a counter electrode to apply a voltage to the magnetic particles trapped by the magnetic trap means, and to emit a luminescence, a light detection element to detect a luminescence derived from the labeling substance on the magnetic particles trapped in the flow chamber, and regulating means to regulate a region that the light detection element detects the luminescence derived from the labeling substance on a part of magnetic particles of them trapped by the magnetic trap means.

9. 发明申请

US20130277542A1 MASS ANALYZING APPARATUS, ANALYZING METHOD AND CALIBRATION SAMPLE 有权
标题翻译：质量分析仪器，分析方法和校准样品
公开(公告)号：US20130277542A1
公开(公告)日：2013-10-24
申请号：US13978445
申请日：2011-12-27
申请人： Midori Sasaki , Terumi Tamura , Shinya Ito , Makoto Nogami
发明人： Midori Sasaki , Terumi Tamura , Shinya Ito , Makoto Nogami
IPC分类号： H01J49/00
CPC分类号： H01J49/0009
摘要： The mass analyzing apparatus of the present invention can achieve the speed-up and simplification of the formation of a calibration curve for quantifying an analysis object in a mass analyzing apparatus. The mass analyzing apparatus is provided with: a sample storage-dilution unit 1 for storing samples of the analysis object including a quantitative calibrator in which, with respect to one analysis object to be quantified, two or more kinds of compounds selected from the analysis object, a plurality of stable isotope compounds of the analysis object and a plurality of analogue compounds of the analysis object are mixed at respectively different concentrations; an ionizing unit 5 for ionizing a sample; a mass analyzing unit 6 for analyzing the ionized sample; and a data processing unit 7 in which, based on results of analysis of the quantitative calibrator carried out by the mass analyzing unit 6, two or more concentrations are measured, and the analysis object is quantified based on information of the measurement.
摘要翻译：本发明的质量分析装置可以实现加速和简化在质量分析装置中对分析对象进行定量的校准曲线的形成。质量分析装置具备：样本存储稀释单元1，用于存储包括定量校准器的分析对象的样本，其中对于要定量的一个分析对象，选自分析对象中的两种或更多种化合物分析对象的多个稳定的同位素化合物和分析对象的多个类似化合物分别以不同的浓度混合，用于电离样品的电离单元5; 用于分析电离样品的质量分析单元6; 以及数据处理单元7，其中，基于由质量分析单元6执行的定量校准器的分析结果，测量两个或更多个浓度，并且基于测量的信息量化分析对象。

10. 发明申请

US20070202011A1 Automatic analyzing apparatus 有权
标题翻译：自动分析仪
公开(公告)号：US20070202011A1
公开(公告)日：2007-08-30
申请号：US11797240
申请日：2007-05-02
申请人： Keiko Nogawa , Michiaki Sekiguchi , Hiroshi Watanabe , Hiroaki Ishizawa , Terumi Tamura
发明人： Keiko Nogawa , Michiaki Sekiguchi , Hiroshi Watanabe , Hiroaki Ishizawa , Terumi Tamura
IPC分类号： G01N33/00
CPC分类号： G01N35/026 , G01N2035/0415 , G01N2035/0472 , Y10T436/11 , Y10T436/110833 , Y10T436/113332 , Y10T436/114165 , Y10T436/115831
摘要： An automatic analyzing apparatus has an analysis section including an immunity analysis unit and a biochemical componential analysis unit. A sample rack which has undergone the immunity componential analysis is horizontally fed by a rack feeding mechanism from a position confronting the inlet of a rack stationing section to a position near the outlet of the rack stationing section, so that the sample rack is directly moved to a return line, while skipping over the rack stationing section, so as to be efficiently returned to the analysis section and subjected to a subsequent biochemical analysis. A sample rack that needs reexamination by an identical analysis unit is also returned in the same efficient way.
摘要翻译：自动分析装置具有包括免疫分析单元和生化分析单元的分析部。已经经过免疫组分分析的样品架通过齿条进给机构从面向机架定位部分的入口的位置到靠近机架定位部分出口处的位置水平馈送，使样品架直接移动到返回线，同时跳过机架驻留部分，以便有效地返回到分析部分并进行随后的生化分析。需要通过相同分析单元进行复检的样品架也以相同的有效方式返回。

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