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1. 发明授权

US06169046A Absorbable barrier membrane 失效
标题翻译：可吸收阻隔膜
公开(公告)号：US06169046A
公开(公告)日：2001-01-02
申请号：US09044162
申请日：1998-03-19
申请人： Toshiki Shikata , Yasutoshi Kakizawa , Jyunzo Tanaka , Yasushi Suetsugu , Masanori Kikuchi , Hiroo Miyairi , Kazuo Takakuda , Yoshihisa Koyama
发明人： Toshiki Shikata , Yasutoshi Kakizawa , Jyunzo Tanaka , Yasushi Suetsugu , Masanori Kikuchi , Hiroo Miyairi , Kazuo Takakuda , Yoshihisa Koyama
IPC分类号： D04H100
CPC分类号： D04H1/435 , A61B17/6441 , A61F2/2846 , A61F2002/3092 , A61L31/06 , A61L31/127 , A61L31/148 , A61L2430/02 , D04H3/011 , Y10T442/637 , Y10T442/642 , Y10T442/696 , C08L67/04
摘要： The present invention provides an absorbable barrier membrane for guided tissue regeneration which is useful for regeneration of animal tissues, including those of humans, the absorbable barrier membrane being superior in heat stability, processability, reproducibility, storage stability, bioabsorbablity, and tissue regeneration effects, and further provides a method for regeneration, using the absorbable barrier membrane, of a mandible, periodontal tissue, or defective tubulous bone, and particularly a defective tubulous bone which possesses a segmental bone defect in which both ends of the bone are in separate segments. The above objects are attained by an absorbable barrier membrane for use in guided tissue generation, comprising a lactic copolyester in which a polymerization catalyst is deactivated, as an essential component.
摘要翻译：本发明提供一种用于引导组织再生的可吸收阻隔膜，其可用于包括人的动物组织的再生，可吸收的阻隔膜的热稳定性，加工性，再现性，储存稳定性，生物可吸收性和组织再生效果优异，并且还提供了使用可吸收阻隔膜，下颌骨，牙周组织或有缺陷的细小骨，特别是具有节段性骨缺损的不良管状骨的再生的方法，其中骨的两端分开。上述目的是通过用于导向组织生成的可吸收阻隔膜来实现的，其包括其中聚合催化剂失活的乳酸共聚酯作为必要组分。

2. 发明授权

US6110578A Expanded material and laminate 失效
标题翻译：膨胀材料和层压板
公开(公告)号：US6110578A
公开(公告)日：2000-08-29
申请号：US482111
申请日：2000-01-13
申请人： Yasutoshi Kakizawa , Toshiki Shikata
发明人： Yasutoshi Kakizawa , Toshiki Shikata
IPC分类号： C08J9/00 , B32B3/26
CPC分类号： C08J9/00 , C08J2367/02
摘要： The present invention provides a biodegradable expanded material having excellent expandability, moldability, impact resistance, heat resistance and storage stability. The present invention also provides a process for the preparation of the foregoing expanded material. The present invention further provides a laminate of a non-expanded material layer and an expanded material layer prepared from the foregoing expanded material which exhibits excellent impact resistance and heat resistance and an excellent transparency in the non-expanded material even after heat treatment so that a pattern printed on the inner side of the non-expanded material layer can be clearly viewed from the outside. A novel expanded material is provided made of a hydroxycarboxylic acid based polyester having a weight-average molecular weight of from 20,000 to 400,000 comprising as structural units a structural unit derived from hydroxycarboxylic acid, a structural unit derived from molecular weight increasing agent and/or a structural unit derived from polymerization catalyst deactivator.
摘要翻译：本发明提供具有优异的可膨胀性，成型性，耐冲击性，耐热性和储存稳定性的生物降解性发泡材料。本发明还提供了制备上述膨胀材料的方法。本发明还提供一种非发泡材料层和由上述膨胀材料制成的发泡材料层的叠层体，即使在热处理后也显示出优异的抗冲击性和耐热性，并且非发泡材料的透明度优异，可以从外部清楚地看到印刷在非发泡材料层的内侧上的图案。提供一种新型膨胀材料，其由重均分子量为20,000至400,000的羟基羧酸基聚酯制成，其包含衍生自羟基羧酸的结构单元作为结构单元，衍生自分子量增加剂的结构单元和/或衍生自聚合催化剂失活剂的结构单元。

3. 发明授权

US6037384A Expanded material and laminate 失效
公开(公告)号：US6037384A
公开(公告)日：2000-03-14
申请号：US753493
申请日：1996-11-26
申请人： Yasutoshi Kakizawa , Toshiki Shikata
发明人： Yasutoshi Kakizawa , Toshiki Shikata
IPC分类号： C08J9/00
CPC分类号： C08J9/00 , C08J2367/02 , Y10T428/249988
摘要： The present invention provides a biodegradable expanded material having excellent expandability, moldability, impact resistance, heat resistance and storage stability. The present invention also provides a process for the preparation of the foregoing expanded material. The present invention further provides a laminate of a non-expanded material layer and an expanded material layer prepared from the foregoing expanded material which exhibits excellent impact resistance and heat resistance and an excellent transparency in the non-expanded material even after heat treatment so that a pattern printed on the inner side of the non-expanded material layer can be clearly viewed from the outside. A novel expanded material is provided made of a hydroxycarboxylic acid based polyester having a weight-average molecular weight of from 20,000 to 400,000 comprising as structural units a structural unit derived from hydroxycarboxylic acid, a structural unit derived from molecular weight increasing agent and/or a structural unit derived from polymerization catalyst deactivator.

4. 发明授权

US5955529A Biodegradable material and process for the preparation thereof 失效
标题翻译：可生物降解材料及其制备方法
公开(公告)号：US5955529A
公开(公告)日：1999-09-21
申请号：US897140
申请日：1997-07-21
申请人： Yoji Imai , Yasutoshi Kakizawa , Masao Kamikura , Toshiki Shikata
发明人： Yoji Imai , Yasutoshi Kakizawa , Masao Kamikura , Toshiki Shikata
IPC分类号： A61B17/56 , A61B17/00 , A61F2/02 , A61F2/28 , A61F2/46 , A61K6/00 , A61K9/00 , A61K9/20 , A61L27/00 , A61L27/46 , A61L27/56 , A61L33/00 , C08K3/32 , C08F20/00
CPC分类号： A61L27/46 , A61K9/2009 , A61K9/204 , A61L27/56 , C08K3/32 , A61B2017/00004 , A61F2/28 , A61F2002/2817 , A61F2002/30062 , A61F2002/4631 , A61F2210/0004
摘要： The present invention provides a biodegradable material having excellent organic compatibility, moldability, mechanical properties, biodegradability and storage stability which can be used as bone substitute material, material for osteosynthesis, bone filling material, dental material, material having controlled release of chemical, material having controlled release of physiologically active compound or the like and a process for the preparation thereof. A novel biodegradable material is provided, comprising as essential components a lactic acid-based polymer (A) consisting of structural units (a) derived from lactic acid components and polyester structural units (b) derived from dicarboxylic acid components and diol components, the weight ratio of (a)/(b) being from 98/2 to 20/80, and a calcium phosphate-based compound (B), wherein the weight ratio of (A)/(B) is from 99/1 to 30/70. A process for the preparation of such a biodegradable material is also provided.
摘要翻译：本发明提供一种生物可降解材料，其具有优异的有机相容性，成型性，机械性能，生物降解性和储存稳定性，可用作骨替代材料，骨接合材料，骨填充材料，牙科材料，具有化学控制释放的材料，具有生理活性化合物等的控制释放及其制备方法。提供了一种新型的可生物降解材料，作为必要成分，由来自乳酸成分的结构单元（a）和由二羧酸成分和二醇成分得到的聚酯结构单元（b）构成的乳酸类聚合物（A）（A）/（b）的比例为98/20〜20/80，磷酸钙系化合物（B）的重量比为99/1〜30 / 70。还提供了一种制备这种可生物降解材料的方法。

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