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1. 发明授权

US5476573A Apparatus for defoaming and controlling aerobic culture fermentation 失效
标题翻译：消泡和控制好氧培养发酵装置
公开(公告)号：US5476573A
公开(公告)日：1995-12-19
申请号：US980291
申请日：1992-11-23
申请人： Toshiki Hirose , Koji Shimazaki , Takashi Nakamura , Atsuo Shiraishi , Hiroki Kawashima , Tatsuya Nakayama
发明人： Toshiki Hirose , Koji Shimazaki , Takashi Nakamura , Atsuo Shiraishi , Hiroki Kawashima , Tatsuya Nakayama
IPC分类号： C12M1/00 , C12M1/04 , C12M1/21 , C12N1/00
CPC分类号： C12M41/02 , C12M29/02 , C12M29/20 , Y10S435/812
摘要： An apparatus and method for defoaming aerobic fermentation cultures is provided, where the amount of liquid culture medium used is greater than that in conventional aerobic cultures (70% or more of the total capacity of the culture tank) without lowering the productivity of the intended, desired product. In the present apparatus and method, a device for separating vapor from liquid of a foam is in fluid communication with the fermentation tank, a device for condensing residual liquid of the vapor received from the separating device is in fluid communication with the separating device, and a sensor for detecting foams is provided in a location along the fluid communication pathway. In the defoaming apparatus, an optional defoaming device is provided, which may be based on either a rotary body rotating at a high speed by use of an electric motor which beats the foams, or on a centrifugal atomizer. The defoaming device may be provided between the vapor-liquid separating device and the condensing device.
摘要翻译：提供了一种用于消泡需氧发酵培养物的装置和方法，其中使用的液体培养基的量大于常规需氧培养物（培养罐的总容量的70％以上）的量，而不降低预期的，所需产品。在本发明的装置和方法中，用于将泡沫中的蒸汽与液体分离的装置与发酵罐流体连通，用于冷凝从分离装置接收的蒸汽的残留液体与分离装置流体连通的装置，用于检测泡沫的传感器设置在沿着流体连通路径的位置。在消泡装置中，提供了可选的消泡装置，其可以基于通过使用打开泡沫的电动机高速旋转的旋转体或离心式雾化器。可以在气液分离装置和冷凝装置之间设置消泡装置。

2. 发明授权

US6025169A Process for production of lysine by fermentation 有权
标题翻译：通过发酵生产赖氨酸的方法
公开(公告)号：US6025169A
公开(公告)日：2000-02-15
申请号：US192565
申请日：1998-11-17
申请人： Takashi Nakamura , Tatsuya Nakayama , Yosuke Koyama , Keishi Shimazaki , Harufumi Miwa , Minoru Tsuruta , Koji Tamura , Osamu Tosaka
发明人： Takashi Nakamura , Tatsuya Nakayama , Yosuke Koyama , Keishi Shimazaki , Harufumi Miwa , Minoru Tsuruta , Koji Tamura , Osamu Tosaka
IPC分类号： C12M1/36 , C12N1/20 , C12P1/00 , C12P13/06 , C12P13/08
CPC分类号： C12M41/32 , C12M41/26 , C12M41/34 , C12M41/48 , C12N1/20 , C12P13/08 , Y10S435/822 , Y10S435/948
摘要： The present invention relates to a method for controlling carbon source concentration in the aerobic cultivation of a microorganism. The substrate carbon source remains at a low level in a cultivation vessel during the culture feeding in aerobic fed-batch, continuous or cell-recycling continuous cultures. This is accomplished by monitoring the increase in pH or dissolved oxygen content in the culture medium and adding the feed solution intermittently into a cultivation vessel at a calculated feed rate using a feed control device controlled by a computer.The present invention further relates to a process for producing L-lysine by fermentation having the advantages over the prior methods, those being improved productivity, higher concentrations of accumulated product, and increased yields of L-lysine.
摘要翻译：本发明涉及一种控制微生物需氧培养中碳源浓度的方法。在需氧补料分批，连续或细胞循环连续培养的培养进料期间，底物碳源在培养容器中保持在低水平。这是通过监测培养基中pH或溶解氧含量的增加并使用由计算机控制的进料控制装置以计算的进料速率间歇地将进料溶液加入到培养容器中来实现的。本发明还涉及通过发酵生产L-赖氨酸的方法，其具有优于现有方法的优点，即提高生产率，较高浓度的积累产物和增加的L-赖氨酸的产率。

3. 发明授权

US5912113A Method and apparatus for controlling carbon source concentration in aerobic cultivation of a microorganism 失效
标题翻译：用于控制微生物需氧培养中碳源浓度的方法和装置
公开(公告)号：US5912113A
公开(公告)日：1999-06-15
申请号：US905713
申请日：1997-08-04
申请人： Takashi Nakamura , Tatsuya Nakayama , Yosuke Koyama , Keishi Shimazaki , Harufumi Miwa , Minoru Tsuruta , Koji Tamura , Osamu Tosaka
发明人： Takashi Nakamura , Tatsuya Nakayama , Yosuke Koyama , Keishi Shimazaki , Harufumi Miwa , Minoru Tsuruta , Koji Tamura , Osamu Tosaka
IPC分类号： C12M1/36 , C12N1/20 , C12P1/00 , C12P13/06 , C12P13/08 , C12Q3/00 , C12N1/12 , C12N1/14
CPC分类号： C12M41/32 , C12M41/26 , C12M41/34 , C12M41/48 , C12N1/20 , C12P13/08 , Y10S435/822 , Y10S435/948
摘要： The present invention is a method for aerobically cultivating yeast or bacteria in a culture medium of fed-batch, continuous or cell-recycling continuous cultures, wherein the carbon source concentration in the culture medium is maintained at a constant low level of under g/l. The carbon source concentration is maintained by measuring the carbon consumption of a culture of the yeast or bacteria in a preliminary experiment. The rate is determined between the time the culture is started and a time when the carbon source is exhausted. A feeding time is then determined wherein the activity of the yeast or bacteria in the presence of the carbon source does not change and a volume of the carbon source to be used in a first feeding (So) is set as So=.nu..times.T. Then, in a main culture, a first feeding of a volume of the carbon source (So) is added for the time (T), and the exhaustion of the carbon source is detected as an increase in pH or an increase in concentration of oxygen dissolved in the culture medium. A second feeding of a volume of the carbon source is then added for the time (T), and the feeding rate is determined based on a period (.tau.) before which the second feeding is added as follows:if 10 min..gtoreq..tau., the feeding rate of the feed solution is set at 1.1.times..nu.;if 30 min..gtoreq..tau.>10 min., the feeding rate of the feed solution is set at .nu.;if 60 min..gtoreq..tau.>30 min., the feeding rate is set at 0.9.times..nu.; orif 120 min..gtoreq..tau.>60 min., the feeding rate is set at 0.8.times..nu.. By modifying the feeding rate in this way, the carbon source concentration in the cultivation vessel is kept at the constant low level of under 5 g/l.
摘要翻译：本发明是在补料分批，连续或细胞循环连续培养的培养基中有氧培养酵母或细菌的方法，其中培养基中的碳源浓度保持在低于g / l的恒定低水平。通过在初步实验中测量酵母或细菌的培养物的碳消耗来维持碳源浓度。速率是在文化开始时间和碳源耗尽时间之间确定的。然后确定进料时间，其中在碳源存在下酵母或细菌的活性不变，并且在第一次进料（So）中使用的碳源的体积被设定为So = nu xT。然后，在主培养中，在时间（T）下加入体积的碳源（So）的第一次进料，并且随着pH的增加或氧浓度的增加检测碳源的耗尽溶解在培养基中。然后在时间（T）下加入体积的碳源的第二次进料，并且基于如下加入第二次进料的时间段（τ）确定进料速率：如果10分钟> / = tau，进料溶液的进料速率设定为1.1×nu; 如果30分钟，则进料溶液的进料速度设定为nu; 如果60分钟> 30分钟，进料速率设定为0.9x nu; 或者如果120分钟，则进料速率设定为0.8x nu。通过以这种方式改变进料速率，培养容器中的碳源浓度保持在5g / l以下的恒定低水平。

4. 发明授权

US09127635B2 Method of generating spray by fluid injection valve, fluid injection valve, and spray generation apparatus 有权
标题翻译：通过流体注射阀，流体注射阀和喷雾生成装置产生喷雾的方法
公开(公告)号：US09127635B2
公开(公告)日：2015-09-08
申请号：US13281082
申请日：2011-10-25
申请人： Mamoru Sumida , Tatsuya Nakayama , Norihisa Fukutomi , Keisuke Ito
发明人： Mamoru Sumida , Tatsuya Nakayama , Norihisa Fukutomi , Keisuke Ito
IPC分类号： F02D1/06 , F02M61/00 , F02M61/18
CPC分类号： F02M61/1806 , F02M61/18 , F02M61/1846 , F02M61/1853 , F02M61/186
摘要： A method of generating a spray by a fluid injection valve is provided. The fluid injection valve includes a valve seat (10), a valve body (8), and an orifice plate (11) having a plurality of orifices (12). The flows in the orifices and the flows directly below the orifices are configured to be substantially liquid film flows. The directions of jet flows (30), (31) from the respective orifices (12) are not necessarily matched to the central axis directions of the orifices and are not necessarily intersected with each other at a downstream position thereof. The sprays are caused to converge by the Coanda effect acting on a plurality of sprays after jet flows from the orifices (12) become sprays at a downstream position farther than a break-up length (a). The convergence of the sprays is continued until the Coanda effect is substantially lost.
摘要翻译：提供了一种通过流体注射阀产生喷雾的方法。流体喷射阀包括阀座（10），阀体（8）和具有多个孔（12）的孔板（11）。孔口中的流动以及直接在孔口下方的流动被构造成基本上是液体膜流。来自各个孔口（12）的喷流（30），（31）的方向不一定与孔口的中心轴线方向一致，并不一定在其下游位置彼此相交。在从喷孔（12）喷射流动到比分解长度（a）更远的下游位置喷雾时，喷雾剂被作用在多个喷雾上的柯安达效应会聚。喷雾剂的融合持续进行，直到柯恩达效应显着丧失。

5. 发明申请

US20070023230A1 Variable resonator 失效
标题翻译：可变谐振器
公开(公告)号：US20070023230A1
公开(公告)日：2007-02-01
申请号：US11338716
申请日：2006-01-25
申请人： Tatsuya Nakayama , Mikihiko Suzuki
发明人： Tatsuya Nakayama , Mikihiko Suzuki
IPC分类号： F01N1/08 , F01N1/16
CPC分类号： F02M35/1255
摘要： A communicating pipe is disposed on an outer periphery of an air intake pipe, and a conduit is formed so as to be parallel to an air intake passage. A plurality of first communicating apertures are disposed through the air intake pipe so as to be arranged in a single row in a conduit direction and communicate between the conduit and the air intake passage. A resonance chamber is mounted to the communicating pipe so as to communicate with a first end of the conduit. A movable member is disposed so as to be movable in the conduit direction by sliding in contact with the inner wall surface of the communicating pipe. A second communicating aperture is disposed through the movable member so as to be placed above the first communicating apertures. A communicating channel length between the air intake passage and the resonance chamber is adjusted by changing a position of overlap of the second communicating aperture relative to the first communicating apertures by moving the movable member in the conduit direction.
摘要翻译：连通管布置在进气管的外周上，并且形成为与进气通道平行的导管。多个第一连通孔通过进气管设置成沿导管方向排列成一排，并且在导管和进气通道之间连通。共鸣室安装在连通管上，以与导管的第一端连通。可动构件通过与连通管的内壁面的滑动滑动而配置成能够在导管方向上移动。第二连通孔设置成穿过可动构件以便放置在第一连通孔的上方。通过沿导管方向移动可动件，改变第二连通孔相对于第一连通孔的重叠位置来调节进气通道和共鸣室之间的连通通道长度。

6. 发明授权

US5654779A Liquid crystal display device having a removable holding member for the light source 失效
标题翻译：具有用于光源的可移除保持构件的液晶显示装置
公开(公告)号：US5654779A
公开(公告)日：1997-08-05
申请号：US365791
申请日：1994-12-29
申请人： Tatsuya Nakayama , Takanori Takaki , Seiki Takahashi , Toshio Tobita
发明人： Tatsuya Nakayama , Takanori Takaki , Seiki Takahashi , Toshio Tobita
IPC分类号： G02B6/00 , F21S8/00 , F21V8/00 , G02F1/1335 , G02F1/13357 , G02F1/1333 , F21V7/04 , G01D11/28
CPC分类号： G02F1/1336 , F21S8/00 , G02B6/0001 , F21Y2103/00 , G02F2203/68 , Y10S345/905 , Y10S385/901
摘要： A liquid crystal display device adaptable for various applications is provided which comprises a liquid crystal display panel, lamps, lamp holders respectively holding the lamps, a photoconductive board provided between the lamps, and a frame covering both the lamps and the lamp holders, wherein the photoconductive board comprises an outer photoconductive part fixed to the lamp holders, and an inner photoconductive part held on the rear side thereof by a holding member provided to the frame.
摘要翻译：提供了适用于各种应用的液晶显示装置，其包括液晶显示面板，灯，分别保持灯的灯座，设置在灯之间的感光基板和覆盖灯和灯座的框架，其中，光电导体板包括固定到灯座的外部光电导部分，以及通过设置在框架上的保持部件而在其后侧保持的内部光电导部分。

7. 发明授权

US07334663B2 Variable resonator 失效
标题翻译：可变谐振器
公开(公告)号：US07334663B2
公开(公告)日：2008-02-26
申请号：US11338716
申请日：2006-01-25
申请人： Tatsuya Nakayama , Mikihiko Suzuki
发明人： Tatsuya Nakayama , Mikihiko Suzuki
IPC分类号： F01N1/02 , F01N1/12 , F02M35/12 , F01N1/08 , F02M35/10 , F02M35/14
CPC分类号： F02M35/1255
摘要： A communicating pipe is disposed on an outer periphery of an air intake pipe, and a conduit is formed so as to be parallel to an air intake passage. A plurality of first communicating apertures are disposed through the air intake pipe so as to be arranged in a single row in a conduit direction and communicate between the conduit and the air intake passage. A resonance chamber is mounted to the communicating pipe so as to communicate with a first end of the conduit. A movable member is disposed so as to be movable in the conduit direction by sliding in contact with the inner wall surface of the communicating pipe. A second communicating aperture is disposed through the movable member so as to be placed above the first communicating apertures. A communicating channel length between the air intake passage and the resonance chamber is adjusted by changing a position of overlap of the second communicating aperture relative to the first communicating apertures by moving the movable member in the conduit direction.
摘要翻译：连通管布置在进气管的外周上，并且形成为与进气通道平行的导管。多个第一连通孔通过进气管设置成沿导管方向排列成一排，并且在导管和进气通道之间连通。共鸣室安装在连通管上，以与导管的第一端连通。可动构件通过与连通管的内壁面的滑动滑动而配置成能够在导管方向上移动。第二连通孔设置成穿过可动构件以便放置在第一连通孔的上方。通过在导管方向上移动可动件，改变第二连通孔相对于第一连通孔的重叠位置来调节进气通道和共鸣室之间的连通通道长度。

8. 发明授权

US09739247B2 Mist forming method using fluid injection valve, fluid injection valve, and mist forming apparatus 有权
公开(公告)号：US09739247B2
公开(公告)日：2017-08-22
申请号：US13428027
申请日：2012-03-23
申请人： Mamoru Sumida , Tatsuya Nakayama
发明人： Mamoru Sumida , Tatsuya Nakayama
IPC分类号： F02M61/00 , F02M61/18 , F02M61/16
CPC分类号： F02M61/184 , F02M61/162 , F02M61/18 , F02M61/1806 , F02M61/1813 , F02M61/1853 , F02M61/186
摘要： A mist forming method using a fluid injection valve formed of a valve seat, a valve body, and a nozzle portion or an injection hole plate having injection holes, and configured to turn in-hole flows and flows immediately below the injection holes into substantially liquid film flows. Directions of jets from the injection holes are not necessarily brought into coincidence with a center axis direction of the injection holes and are not necessarily crossed with one another in a downstream part, and after the jets turned into mists at a position downstream of a break length position, the mists are allowed to come close or gather by the Coanda effect so as to appear substantially as one solid mist, and allowed to keep gathering until catching of ambient air and a resulting air flow along a downstream flow direction in a predetermined in-mist portion attenuate.

9. 发明授权

US06201586B1 Liquid crystal display having stoppers on back light or outer frame or having particular features of the low voltage wiring 失效
标题翻译：具有在背光或外框上具有止动器或具有低电压布线的特定特征的液晶显示器
公开(公告)号：US06201586B1
公开(公告)日：2001-03-13
申请号：US09009179
申请日：1998-01-20
申请人： Tatsuya Nakayama
发明人： Tatsuya Nakayama
IPC分类号： G02F11333
CPC分类号： G02B6/0031 , G02B6/0055 , G02B6/0083 , G02B6/0086 , G02F1/133308 , G02F1/133615 , G02F2001/133314
摘要： A liquid crystal display comprises: a plane light guide plate having an illumination surface which emits a light guided through a front end face portion from front face portion to outside; a liquid crystal panel which is disposed on front face of the illumination surface of the light guide plate and controls a transmission of light by electric signal supplied through a circuit board; a light source which is disposed adjacent to the front end face portion of the light guide plate in parallel thereto; and a main reflector attached to the front end portion of the light guide plate surrounding the light source; in which stoppers 6 are mounted on a holder 2 being a component of the light source to regulate free movement of the liquid crystal panel, whereby the liquid crystal display is small-sized. Further, a low voltage side wiring of a wiring section for supplying a power to the light source is formed by arranging a wiring material or wiring pattern of thin insulated strip on the light guide plate, etc.
摘要翻译：液晶显示器包括：平面导光板，其具有照射表面，其照射从前表面部分到外部的前端面部分引导的光; 液晶面板，其设置在所述导光板的照明面的前面，通过电路板供给的电信号控制光的透过; 与导光板的前端面部平行配置的光源; 以及主反射器，其安装在围绕光源的导光板的前端部; 其中止挡件6安装在作为光源的部件的保持器2上，以调节液晶面板的自由移动，由此液晶显示器是小尺寸的。此外，通过在导光板等上布置薄绝缘条的布线材料或布线图案，形成用于向光源供电的布线部分的低压侧布线。

10. 发明授权

US5424857A Matrix-type display apparatus with conductor wire interconnecting capacitor electrodes 失效
标题翻译：具有互连电容电极导体线的矩阵式显示装置
公开(公告)号：US5424857A
公开(公告)日：1995-06-13
申请号：US263084
申请日：1994-06-21
申请人： Hironori Aoki , Naoki Nakagawa , Tatsuya Nakayama
发明人： Hironori Aoki , Naoki Nakagawa , Tatsuya Nakayama
IPC分类号： G02F1/133 , G02F1/1343 , G02F1/136 , G02F1/1362 , G02F1/1368 , G09F9/30 , H01L29/78 , H01L29/786
CPC分类号： G02F1/136213 , G02F1/1368 , G02F2001/13629
摘要： A matrix-type display having a TFT substrate provided with at least a pixel electrode and a thin film transistor; and an opposing electrode; wherein a material for changing an optical property is interposed between the TFT substrate and the opposing electrode; a plurality of thin film transistors arrange in a matrix array on a transparent insulative substrate, each of the thin film transistors being provided to each pixel; a gate signal line interconnecting respective gate electrodes of the thin film transistors arrange in a row or column of the matrix array; a source electrode line interconnecting respective source or drain electrodes of thin film transistor arranged in a column or row of the matrix array; a pixel electrode formed of a transparent conductor film and connected to the source or drain electrode of each of the thin film transistors; a capacitor electrode capacitively coupled to the pixel electrode through a dielectric film; a conductor wire interconnecting the respective capacitive electrode of the pixels interconnected by the gate signal line, wherein the conductor wire is formed integrally with the capacitor electrode, wherein the gate signal line is formed above the conductor wire with the dielectric film intervening therebetween, and wherein the conductor wire interconnecting the respective capacitor electrode of the pixels arranged along the gate signal line.
摘要翻译：具有设置有至少像素电极和薄膜晶体管的TFT基板的矩阵型显示器; 和相对电极; 其中用于改变光学特性的材料插入在所述TFT基板和所述相对电极之间; 将多个薄膜晶体管以矩阵阵列排列在透明绝缘基板上，每个薄膜晶体管设置在每个像素上; 互连所述薄膜晶体管的各个栅极的栅极信号线，排列成矩阵阵列的一行或一列; 源极电极线，其互连布置在矩阵阵列的列或行中的薄膜晶体管的各个源极或漏极; 由透明导体膜形成并连接到每个薄膜晶体管的源极或漏极的像素电极; 通过电介质膜电容耦合到像素电极的电容器电极; 将由栅极信号线互连的像素的各个电容电极互连的导体线，其中，导体线与电容器电极一体地形成，其中栅极信号线形成在导体线之上，电介质膜介于其间，其中所述导体线将沿着栅极信号线布置的像素的各个电容电极互连。

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