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1. 发明申请

US20090325187A1 Immunomodulation 审中-公开
标题翻译：免疫调节
公开(公告)号：US20090325187A1
公开(公告)日：2009-12-31
申请号：US11662919
申请日：2004-09-15
申请人： Torsten Witte , Torsten Matthias
发明人： Torsten Witte , Torsten Matthias
IPC分类号： G01N33/53 , C07K14/00 , C07K16/18
CPC分类号： C07K14/70503 , C07K2319/21
摘要： Medical use of ILT6 for modulating the immune response, as well as to pharmaceutical compositions containing ILT6.In a further aspect, the present invention relates to the medical treatment of human beings using ILT6 to modulate their immune response, for example directed against heterologous and/or autologous antigens. Furthermore, the present invention relates to the analysis using ILT6 for diagnostic purposes and to diagnostic compositions that can be employed for that analysis.
摘要翻译：医学使用ILT6调节免疫应答，以及含有ILT6的药物组合物。在另一方面，本发明涉及使用ILT6调节其免疫应答的人的医学治疗，例如针对异源和/或自体抗原。此外，本发明涉及用于诊断目的的使用ILT6的分析和可用于该分析的诊断组合物。

2. 发明申请

US20070184502A1 Method of diagnosing Sjogren's syndrome 审中-公开
标题翻译：诊断干燥综合征的方法
公开(公告)号：US20070184502A1
公开(公告)日：2007-08-09
申请号：US11406524
申请日：2006-04-19
申请人： Torsten Matthias , Torsten Witte
发明人： Torsten Matthias , Torsten Witte
IPC分类号： G01N33/53 , C12M1/34
CPC分类号： G01N33/6893 , G01N33/564 , G01N2800/101
摘要： The invention relates to a method of diagnosing Sjögren's syndrome and to a suitable kit of reagents.
摘要翻译：本发明涉及诊断Sjögren综合征的方法和合适的试剂盒。

3. 发明授权

US11099178B2 Device and method for detecting substances present in biological or chemical samples 有权
公开(公告)号：US11099178B2
公开(公告)日：2021-08-24
申请号：US14354910
申请日：2012-10-29
申请人： Torsten Matthias
发明人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
IPC分类号： G01N33/543 , G01N35/00 , G01N35/02
摘要： The present invention relates to a device and a method for detecting substances which are present in biological or chemical samples, each substance producing an optically detectable signal upon reaction with a reagent. The device further comprises a sample carrier with at least two receptacles for receiving samples and is characterized in that at least part of the receptacle is equipped to receive at least 2 reagents each, and in that a camera for recording an image which shows at least one receptacle filled with at least two reagents for the detection of different substances, and an evaluation device for evaluating the samples which device is designed such as to evaluate each image by analyzing the signals in the image. Said method comprises the following steps: Introducing at least two reagents into one receptacle of a sample carrier, and optionally immobilizing the reagents, adding the sample to the receptacle, recording an image by means of a camera such that the image shows the receptacle which is loaded with at least two reagents, and evaluating the image by analyzing the color spectrum of the samples in the image.

4. 发明申请

US20140320642A1 Device And Method For Detecting Substances Present In Biological Or Chemical Samples 审中-公开
标题翻译：用于检测存在于生物或化学样品中的物质的装置和方法
公开(公告)号：US20140320642A1
公开(公告)日：2014-10-30
申请号：US14354870
申请日：2012-10-29
申请人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
发明人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
IPC分类号： G01N21/25 , G01N21/27
CPC分类号： G01N21/253 , G01N21/272 , G01N21/6452 , G01N21/78 , G01N2021/0325 , G01N2021/6417 , G01N2021/6423 , G01N2021/6441
摘要： The present invention relates to a device and a method for detecting substances which are present in biological or chemical samples, each substance producing an optically detectable signal upon reaction with a reagent. The device further comprises a sample support with at least two containers for receiving samples and is characterized by a camera for recording an image which shows at least two containers, and an evaluation device for evaluating the samples which device is designed such as to evaluate each image by analyzing the signals in the image. Said method comprises containers, recording an image by means of a camera such that the image shows the at least two containers, and evaluating the image by analyzing the signals in the image.
摘要翻译：本发明涉及一种用于检测存在于生物或化学样品中的物质的装置和方法，每种物质在与试剂反应时产生可光学检测的信号。该装置还包括具有用于接收样品的至少两个容器的样品支架，其特征在于用于记录显示至少两个容器的图像的照相机，以及用于评估样品的评估装置，该装置被设计为评估每个图像通过分析图像中的信号。所述方法包括容器，通过照相机记录图像，使得图像显示至少两个容器，并通过分析图像中的信号来评估图像。

5. 发明授权

US08066471B2 Annular flow duct for a turbomachine through which a main flow can flow in the axial direction 有权
标题翻译：用于涡轮机的环形流道，主流通过该流道可沿轴向流动
公开(公告)号：US08066471B2
公开(公告)日：2011-11-29
申请号：US12227928
申请日：2007-05-29
申请人： Romain Bayere , Malte Blomeyer , Christian Cornelius , Torsten Matthias , Uwe Sieber
发明人： Romain Bayere , Malte Blomeyer , Christian Cornelius , Torsten Matthias , Uwe Sieber
IPC分类号： F04D27/02
CPC分类号： F01D5/145 , F01D5/143 , F04D29/526 , F04D29/685
摘要： Disclosed is an annular flow duct for a turbomachine, the flow duct arranged concentrically about a machine axis running in the axial direction and defined by a boundary wall of circular cross section for directing a main flow, wherein the boundary wall has a plurality of return flow passages distributed over its circumference and through which in each case a partial flow is detached from the main flow at a bleed position and returned to the main flow at a feed position situated upstream of the bleed position, and having aerofoils, arranged radically in the flow duct, of a blade ring, the aerofoil tips of which lie opposite the boundary wall, with a gap formed in each case, wherein the aerofoils are movable in a predetermined rotation direction along the circumference of the boundary wall. Furthermore, a compressor which is insensitive to pumping and flow separations, as viewed in rotation direction, the bleed position of each return flow passage lies upstream of the corresponding feed position.
摘要翻译：公开了一种用于涡轮机的环形流动管道，该流动管道围绕沿着轴向运动的机器轴线同心地布置并且由用于引导主流量的圆形横截面的边界壁限定，其中边界壁具有多个回流分布在其圆周上的通道，并且在每种情况下，部分流动在出口位置处与主流体分离，并且在位于排放位置上游的进给位置处返回到主流体，并且具有从根本上排列在流体中的机翼一个叶片环的管道，其机翼尖头与边界壁相对，在每种情况下形成间隙，其中翼型件可沿着边界壁的圆周沿预定的旋转方向移动。此外，从旋转方向观察对泵送和流动分离不敏感的压缩机，每个返回流动通道的排放位置位于相应进给位置的上游。

6. 发明授权

US09734420B2 Device and method for inspecting a volume of a sample 有权
公开(公告)号：US09734420B2
公开(公告)日：2017-08-15
申请号：US14354782
申请日：2012-10-29
申请人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
发明人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
IPC分类号： G06K9/32 , G06K9/00 , G06F19/00 , G01N1/14 , G01N21/59 , G01F23/292 , G01N35/10 , G06T7/00
CPC分类号： G06K9/3216 , G01F23/292 , G01N35/1016 , G01N2035/1025 , G06T7/0012
摘要： The present invention relates to a device useful for inspecting a sample. The device includes a camera in order to arrange that camera in an image field so that an interface line and a marker of the camera can be imaged as a recorded image. The device also has an evaluation unit which allows an evaluation of the recorded image and the marking in order to provide information to the observer.

7. 发明授权

US09057281B2 Axial turbomachine having an axially displaceable guide-blade carrier 有权
标题翻译：轴向涡轮机具有可轴向移动的导向叶片载体
公开(公告)号：US09057281B2
公开(公告)日：2015-06-16
申请号：US13260406
申请日：2010-03-22
申请人： Francois Benkler , Andreas Böttcher , Uwe Kahlstorf , Torsten Matthias , Dieter Minninger , Oliver Schneider , Peter Schröder , Vyacheslav Veitsman
发明人： Francois Benkler , Andreas Böttcher , Uwe Kahlstorf , Torsten Matthias , Dieter Minninger , Oliver Schneider , Peter Schröder , Vyacheslav Veitsman
IPC分类号： F01D1/04 , F01D11/22
CPC分类号： F01D11/22 , F05D2230/64 , F05D2230/644 , F05D2250/314 , F05D2260/50
摘要： An axial turbomachine including a rotor-blade cascade is provided. The turbomachine includes a casing in which the cascade is installed and a guide-blade carrier which encloses the cascade and is integrated into the inner side of the housing. The guide-blade carrier is arranged immediately adjacently to the blade tips faulting a radial gap, wherein the guide-blade carrier is mounted in the housing, such that it may be displaced parallel to the axis of the axial turbomachine, and includes an adjusting ring which is supported on contact surfaces on the housing and guide-blade carrier and may be rotated about the axis, wherein the contact surfaces of the adjusting ring and of the housing and/or of the guide-blade carrier are set with respect to a plane perpendicular to the axis, so that, when the adjusting ring is rotated about the axis, the guide-blade carrier is displaced axially by the adjusting ring.
摘要翻译：提供了包括转子叶片级联的轴向涡轮机。涡轮机包括其中安装有级联的壳体和围绕级联的导向叶片载体并且整合到壳体的内侧。引导叶片托架被紧紧地布置在与刀片尖端相邻的位置上，该刀片尖端具有径向间隙，其中引导刀片托架安装在壳体中，使得其可以平行于轴向涡轮机的轴线移位，并且包括调节环其被支撑在壳体和引导叶片载体上的接触表面上并且可以围绕轴线旋转，其中调节环和壳体的接触表面和/或引导叶片载体的接触表面相对于平面垂直于轴线，使得当调节环围绕轴线旋转时，导向叶片托架由调节环轴向移动。

8. 发明申请

US20140315226A1 Device And Method For Detecting Substances Present In Biological Or Chemical Samples 审中-公开
标题翻译：用于检测存在于生物或化学样品中的物质的装置和方法
公开(公告)号：US20140315226A1
公开(公告)日：2014-10-23
申请号：US14354910
申请日：2012-10-29
申请人： Torsten MATTHIAS
发明人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
IPC分类号： G01N33/543
CPC分类号： G01N33/54306 , G01N35/00 , G01N35/028
摘要： The present invention relates to a device and a method for detecting substances which are present in biological or chemical samples, each substance producing an optically detectable signal upon reaction with a reagent. The device further comprises a sample carrier with at least two receptacles for receiving samples and is characterized in that at least part of the receptacle is equipped to receive at least 2 reagents each, and in that a camera for recording an image which shows at least one receptacle filled with at least two reagents for the detection of different substances, and an evaluation device for evaluating the samples which device is designed such as to evaluate each image by analyzing the signals in the image. Said method comprises the following steps: Introducing at least two reagents into one receptacle of a sample carrier, and optionally immobilizing the reagents, adding the sample to the receptacle, recording an image by means of a camera such that the image shows the receptacle which is loaded with at least two reagents, and evaluating the image by analyzing the color spectrum of the samples in the image.
摘要翻译：本发明涉及一种用于检测存在于生物或化学样品中的物质的装置和方法，每种物质在与试剂反应时产生可光学检测的信号。该装置还包括具有用于接收样品的至少两个容器的样品载体，其特征在于，所述容器的至少一部分被配备为每个容纳至少两个试剂，并且其中，用于记录图像的照相机，其显示至少一个充满至少两种用于检测不同物质的试剂的容器，以及用于评估设备的样品的评估装置，以便通过分析图像中的信号来评估每个图像。所述方法包括以下步骤：将至少两种试剂引入样品载体的一个容器中，并可选地固定试剂，将样品加入容器中，借助相机记录图像，使得图像显示出容器装载至少两种试剂，并通过分析图像中样品的色谱来评估图像。

9. 发明申请

US20120230829A1 TURBINE OR COMPRESSOR BLADE 审中-公开
标题翻译：涡轮机或压缩机叶片
公开(公告)号：US20120230829A1
公开(公告)日：2012-09-13
申请号：US13510295
申请日：2010-11-16
申请人： Francois Benkler , Marco Link , Torsten Matthias , Marc Mittelbach , Marion Morthorst , Michael Rollmann , Horst Saathoff , Hubertus Michael Wigger
发明人： Francois Benkler , Marco Link , Torsten Matthias , Marc Mittelbach , Marion Morthorst , Michael Rollmann , Horst Saathoff , Hubertus Michael Wigger
IPC分类号： F01D5/14
CPC分类号： F01D5/3007 , F01D5/282 , F05D2230/90 , F05D2260/36 , F05D2300/603
摘要： A blade for a turbine or a compressor, at least partially made of fiber-reinforced plastic, in particular carbon fiber reinforced plastic, being particularly durable under operating conditions is provided. The blade includes a blade body and a blade root. The blade body is substantially made of a folded fabric web made of fiber reinforced plastic, wherein a retaining loop is formed in the area of the fold, and wherein a blade surface is formed in the area of the fold, and wherein a blade surface is formed from the overlapping web ends. The blade root includes a longitudinal beam and at least two holders for anchoring the blade in a corresponding groove of a rotor, the holders being preferably each fixedly connected to the beam at both ends. The blade body is suspended on the beam by means of the retaining loop.
摘要翻译：提供了用于涡轮机或压缩机的叶片，其至少部分由纤维增强塑料制成，特别是碳纤维增强塑料，在操作条件下特别耐用。叶片包括叶片体和叶根。叶片主体基本上由纤维增强塑料制成的折叠织物网制成，其中在折叠区域中形成保持环，并且其中叶片表面形成在折叠区域中，并且其中叶片表面是由重叠的网页末端形成。叶片根部包括纵向梁和用于将叶片锚定在转子的相应凹槽中的至少两个保持器，保持器优选地在两端固定地连接到梁。刀片主体通过保持环悬挂在梁上。

10. 发明授权

US08142719B2 Analysis device 有权
标题翻译：分析装置
公开(公告)号：US08142719B2
公开(公告)日：2012-03-27
申请号：US12291375
申请日：2008-11-07
申请人： Torsten Matthias , Hugo Ribeiro , Hans-Peter Schimon , Peter Van Praet
发明人： Torsten Matthias , Hugo Ribeiro , Hans-Peter Schimon , Peter Van Praet
IPC分类号： G01N21/00 , B01J19/00
CPC分类号： G01N35/025 , G01N35/028 , G01N35/1083 , G01N2035/0455 , Y10T436/11 , Y10T436/111666 , Y10T436/114998
摘要： A device is disclosed, being an analysis device for the study of biological or chemical samples by means of a reagent liquid supplied via a pipette. The device has an instrument housing with a base plate, a working plate arranged on the base plate horizontally to receive the samples in a sample holder having several wells, a robot manipulator arranged above the working plate, which carries a horizontal support arm with a slide. A needle system is fastened to the slide and can move in the Z direction, carrying 3 needles and being brought into vertical positions by a first vertical drive. The needle tips can be placed in an upper position above and in a lower position below a well. The middle needle can move vertically relative to the other two needles, which can be raised and lowered by a second vertical drive. The horizontal spacing of the three needles is so small that all three needles can be positioned with their tips inside the same wells. In particular, the working plate is mounted on the base plate so that it can turn.
摘要翻译：公开了一种用于通过经由移液管供应的试剂液体来研究生物或化学样品的分析装置。该装置具有带有基板的工具壳体，水平地布置在基板上的工作板，用于接收具有多个井的样本保持器中的样本;布置在工作板上方的机器人操纵器，其携带具有滑块的水平支撑臂。针系统固定在滑块上，可沿Z方向移动，携带3针，并通过第一垂直驱动器进入垂直位置。针头可以放置在井下方的上部位置和下部位置。中针可以相对于另外两个针垂直移动，这两个针可以通过第二个垂直驱动器升高和降低。三针的水平间距非常小，以至于所有三个针都可以放置在同一个孔内。特别地，工作板安装在基板上，使其可以转动。

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