专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5331966A Subcutaneous multi-electrode sensing system, method and pacer 失效
标题翻译：皮下多电极感应系统，方法和起搏器
公开(公告)号：US5331966A
公开(公告)日：1994-07-26
申请号：US168725
申请日：1993-12-16
申请人： Tom D. Bennett , William J. Combs , Kallok, Michael J. , Brian B. Lee , Rahul Mehra , George J. Klein
发明人： Tom D. Bennett , William J. Combs , Kallok, Michael J. , Brian B. Lee , Rahul Mehra , George J. Klein
IPC分类号： A61N1/365 , A61B5/0402 , A61N1/362 , A61N1/375 , A61B5/0428
CPC分类号： A61N1/3686 , A61N1/36185 , A61N1/3622 , A61N1/0504 , A61N1/3756 , Y10S128/903
摘要： A method and apparatus for providing an enhanced capability of detecting and gathering electrical cardiac signals via an array of relatively closely spaced subcutaneous electrodes (located on the body of an implanted device) which may be employed with suitable switching circuits, signal processors, and memory to process the electrical cardiac signals between any selected pair or pairs of the electrode array in order to provide a leadless, orientation insensitive means for receiving the electrical signal from the heart. This far-field EGM may be used to provide storage and analysis of arrhythmic events and to provide control signals for the delivery of various therapies including pacing, cardioversion and defibrillation therapies as well as the delivery of antiarrhythmic drugs, and, in the pacing context, to effect capture detection and automatic stimulation threshold adaption, recording of PMT episodes, measurement of refractory periods in order to set timing windows for antitachy pacing therapies, and as a control signal for use in adjusting pacing rate to physiologic demand.
摘要翻译：一种用于提供通过相对紧密间隔的皮下电极（位于植入装置的主体上）的阵列来检测和收集电心电信号的增强能力的方法和装置，其可以与合适的开关电路，信号处理器和存储器一起使用处理任何所选择的一对或一对电极阵列之间的电心脏信号，以便提供用于从心脏接收电信号的无引导方向不敏感的装置。这种远场EGM可用于提供心律失常事件的存储和分析，并提供用于递送各种疗法的控制信号，包括起搏，心脏复律和除颤疗法以及递送抗心律失常药物，并且在起搏背景下，以实现捕获检测和自动刺激阈值适应，记录PMT发作，测量不良期以设置反向起搏治疗的时间窗口，以及用作调整生理需求起搏速率的控制信号。

2. 发明授权

US06968226B2 Method and system for terminating an atrial arrhythmia 失效
标题翻译：终止心房心律失常的方法和系统
公开(公告)号：US06968226B2
公开(公告)日：2005-11-22
申请号：US10059824
申请日：2002-01-30
申请人： Rahul Mehra , George J. Klein , Michael R. Ujhelyi
发明人： Rahul Mehra , George J. Klein , Michael R. Ujhelyi
IPC分类号： A61B5/0402 , A61B5/0472 , A61B17/00 , A61K31/18 , A61M5/142 , A61M5/172 , A61M37/00 , A61N1/362 , A61N1/365 , A61P9/06 , A61B5/04
CPC分类号： A61M5/14244 , A61B2017/00044 , A61M5/1723 , A61M2230/04 , A61N1/3621
摘要： A method and system is provided for responding, from internally within a patient, to an atrial arrhythmia in a heart including measuring from within the patient at least one electrocardiogram characteristic indicative of the atrial arrhythmia, and controlling from within the patient drug therapy delivery to the patient responsive to measuring the at least one electrocardiogram characteristic. Drug therapy is initiated to the patient responsive to measuring the at least one electrocardiogram characteristic. According to one aspect of the present invention, the drug therapy is staged within the patient prior to measuring the at least one electrocardiogram characteristic. According to another example embodiment, the heart is paced from within the patient at a predefined rate responsive to measuring the at least one electrocardiogram characteristic, pacing occurring alone, or in combination with drug therapy.
摘要翻译：提供了一种方法和系统，用于从患者内部响应于心脏中的心房心律失常，包括从患者内测量至少一个指示心房心律失常的心电图特征，以及从患者内控制药物治疗递送至响应于测量至少一个心电图特征的患者。响应于测量至少一个心电图特征，向患者开始药物治疗。根据本发明的一个方面，在测量至少一个心电图特征之前，药物治疗在患者体内分期。根据另一示例性实施例，响应于测量至少一个心电图特征，单独起搏或与药物治疗组合，心脏以预定速率从患者体内起搏。

3. 发明授权

US07951137B2 Method and system for terminating an atrial arrhythmia 有权
标题翻译：终止心房心律失常的方法和系统
公开(公告)号：US07951137B2
公开(公告)日：2011-05-31
申请号：US11244764
申请日：2005-10-06
申请人： Rahul Mehra , George J. Klein , Michael R. Ujhelyi
发明人： Rahul Mehra , George J. Klein , Michael R. Ujhelyi
IPC分类号： A61K9/22 , A61N1/00 , A61B5/04
CPC分类号： A61M5/14244 , A61B2017/00044 , A61M5/1723 , A61M2230/04 , A61N1/3621
摘要： A method and system is provided for responding, from internally within a patient, to an atrial arrhythmia in a heart including measuring from within the patient at least one electrocardiogram characteristic indicative of the atrial arrhythmia, and controlling from within the patient drug therapy delivery to the patient responsive to measuring the at least one electrocardiogram characteristic. Drug therapy is initiated to the patient responsive to measuring the at least one electrocardiogram characteristic. According to one aspect of the present invention, the drug therapy is staged within the patient prior to measuring the at least one electrocardiogram characteristic. According to another example embodiment, the heart is paced from within the patient at a predefined rate responsive to measuring the at least one electrocardiogram characteristic, pacing occurring alone, or in combination with drug therapy.
摘要翻译：提供了一种方法和系统，用于从患者内部响应于心脏中的心房心律失常，包括从患者内测量至少一个指示心房心律失常的心电图特征，以及从患者内控制药物治疗递送至响应于测量至少一个心电图特征的患者。响应于测量至少一个心电图特征，向患者开始药物治疗。根据本发明的一个方面，在测量至少一个心电图特征之前，药物治疗在患者体内分期。根据另一示例性实施例，响应于测量至少一个心电图特征，单独起搏或与药物治疗组合，心脏以预定速率从患者体内起搏。

4. 发明授权

US08512337B2 Method and system for treatment of atrial tachyarrhythmias 有权
标题翻译：治疗房性快速性心律失常的方法和系统
公开(公告)号：US08512337B2
公开(公告)日：2013-08-20
申请号：US10923073
申请日：2004-08-20
申请人： David E. Francischelli , Rahul Mehra
发明人： David E. Francischelli , Rahul Mehra
IPC分类号： A61B18/12
CPC分类号： A61B18/1445 , A61B18/1402 , A61B2017/2945 , A61B2018/00994 , A61B2018/126 , A61B2018/1432 , A61B2018/1472
摘要： A method of and a system for treatment of atrial tachyarrhythmias. The system includes a set of hemostats having elongated opposing jaws carrying mechanisms for applying ablation energy along the jaws. The jaws having straight and curved configurations selected to allow arrangement of the jaws of along opposite sides of walls of a patient's atrium. Treatment is accomplished by applying of ablation energy to the walls of a patient's artria to create lines of lesion corresponding generally to incisions employed in a Maze type procedure.
摘要翻译：一种治疗房性快速性心律失常的方法和系统。该系统包括一组具有延长的相对的夹爪的止血器，该钳口携带用于沿钳口施加消融能量的机构。钳口具有直的和弯曲的构造，其被选择为允许沿着病人心房的壁的相对侧布置钳口。通过将消融能量施加到患者的肌肉的壁上来实现治疗，以产生通常对于迷宫类型手术中使用的切口相应的损伤线。

5. 发明授权

US07561913B2 Automatic adjusting R-wave synchronization algorithm for atrial cardioversion and defibrillation 有权
标题翻译：自动调整心律转复和除颤的R波同步算法
公开(公告)号：US07561913B2
公开(公告)日：2009-07-14
申请号：US10426284
申请日：2003-04-30
申请人： Luc R. Mongeon , Rahul Mehra
发明人： Luc R. Mongeon , Rahul Mehra
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/3987
摘要： An implantable medical device system and method are provided for synchronizing atrial cardioversion shocks to the ventricular rhythm using an adjustable atrial cardioversion/defibrillation ventricular refractory period. Upon determining a need for an atrial shock therapy, the method determines if the ventricular rate meets synchronization criteria based on an upper ventricular refractory period limit. If synchronization criteria are not met, the refractory period is automatically adjusted in stepwise decrements until the synchronization criteria are met, or until a lower refractory period limit is exceeded. If synchronization criteria are met, an atrial shock is synchronized to the next ventricular depolarization occurring outside the current refractory period. If the lower refractory period limit is exceeded, the atrial therapy is aborted.
摘要翻译：提供了一种植入式医疗装置系统和方法，用于使用可调节心房复律/除颤心室不应期使心房心律转复冲击与心室节律同步。在确定需要心房休克治疗后，该方法确定心室率是否满足基于上心室不应期限的同步标准。如果不符合同步标准，则可以逐步递减地自动调整不应期，直到达到同步标准，或直到超过较低的不应期限为止。如果符合同步标准，心房休克与当前不应期以外发生的下一次心室去极化同步。如果超过较低的不应期限，则中止心房治疗。

6. 发明授权

US07435250B2 Method and apparatus for tissue ablation 有权
标题翻译：组织消融的方法和装置
公开(公告)号：US07435250B2
公开(公告)日：2008-10-14
申请号：US11061425
申请日：2005-02-18
申请人： David E. Francischelli , Richard H. Comben , Michael F. Hoey , Rahul Mehra , Jon M. Ocel , Robert Pearson , Paul V. Trescony , Scott E. Jahns
发明人： David E. Francischelli , Richard H. Comben , Michael F. Hoey , Rahul Mehra , Jon M. Ocel , Robert Pearson , Paul V. Trescony , Scott E. Jahns
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B18/1445 , A61B2018/00065 , A61B2018/00351 , A61B2018/00577 , A61B2018/1435 , A61B2018/1472 , A61B2218/002
摘要： A device for ablating tissue is provided. The device comprises a conductive element with a channel for irrigating fluid formed therein, which is in contact with a non-conductive microporous interface. All or a portion of the interface may be removable. When the interface is removed, a portion of the conductive element is exposed for use in ablating tissue. Methods of using the device and of removing the interface are also provided.
摘要翻译：提供了用于消融组织的装置。该装置包括导电元件，其具有用于在其中形成的冲洗流体的通道，其与非导电微孔界面接触。界面的全部或部分可以是可移动的。当界面被去除时，导电元件的一部分被暴露以用于消融组织。还提供了使用设备和移除界面的方法。

7. 发明授权

US06807968B2 Method and system for treatment of atrial tachyarrhythmias 有权
标题翻译：治疗房性快速性心律失常的方法和系统
公开(公告)号：US06807968B2
公开(公告)日：2004-10-26
申请号：US10015690
申请日：2001-12-12
申请人： David E. Francischelli , Rahul Mehra
发明人： David E. Francischelli , Rahul Mehra
IPC分类号： A61B1818
CPC分类号： A61B18/1445 , A61B18/1402 , A61B2017/2945 , A61B2018/00994 , A61B2018/126 , A61B2018/1432 , A61B2018/1472
摘要： A method of and a system for treatment of atrial tachyarrhythmias. The system includes a set of hemostats having elongated opposing jaws carrying mechanisms for applying ablation energy along the jaws. The jaws having straight and curved configurations selected to allow arrangement of the jaws of along opposite sides of walls of a patient's atrium. Treatment is accomplished by applying of ablation energy to the walls of a patient's artria to create lines of lesion corresponding generally to incisions employed in a Maze type procedure.
摘要翻译：一种治疗房性快速性心律失常的方法和系统。该系统包括一组具有延长的相对的夹爪的止血器，该钳口携带用于沿钳口施加消融能量的机构。钳口具有直的和弯曲的构造，其被选择为允许沿着病人心房的壁的相对侧布置钳口。通过将消融能量施加到患者的肌肉的壁上来实现治疗，以产生通常对于迷宫类型手术中使用的切口相应的损伤线。

8. 发明授权

US06572612B2 Ablation catheter and method for isolating a pulmonary vein 有权
公开(公告)号：US06572612B2
公开(公告)日：2003-06-03
申请号：US09975789
申请日：2001-10-11
申请人： Mark T. Stewart , William J. Flickinger , David E. Francischelli , Rahul Mehra , Xiaoyi Min
发明人： Mark T. Stewart , William J. Flickinger , David E. Francischelli , Rahul Mehra , Xiaoyi Min
IPC分类号： A61B1814
CPC分类号： A61B18/1492 , A61B2017/00044 , A61B2017/00243 , A61B2017/00867 , A61B2018/00214 , A61B2018/1407 , A61B2018/1435
摘要： A catheter assembly and method for treatment of cardiac arrhythmia, for example, atrial fibrillation, by electrically isolating a vessel, such as a pulmonary vein, from a chamber, such as the left atrium. The catheter assembly includes a catheter body and at least one electrode. The catheter body includes a proximal portion, an intermediate portion and a distal portion. The intermediate portion extends from the proximal portion and defines a longitudinal axis. The distal portion extends from the intermediate portion and forms a substantially closed loop transverse to the longitudinal axis. The at least one electrode is disposed along the loop. With this configuration, the loop is axially directed into contact with the chamber wall about the vessel ostium. Upon energization, the electrode ablates a continuous lesion pattern about the vessel ostium, thereby electrically isolating the vessel from the chamber.

9. 发明授权

US06325797B1 Ablation catheter and method for isolating a pulmonary vein 有权
标题翻译：消融导管和隔离肺静脉的方法
公开(公告)号：US06325797B1
公开(公告)日：2001-12-04
申请号：US09286048
申请日：1999-04-05
申请人： Mark T. Stewart , William J. Flickinger , David E. Francischelli , Rahul Mehra , Xiaoyi Min
发明人： Mark T. Stewart , William J. Flickinger , David E. Francischelli , Rahul Mehra , Xiaoyi Min
IPC分类号： A61B1814
CPC分类号： A61B18/1492 , A61B2017/00044 , A61B2017/00243 , A61B2017/00867 , A61B2018/00214 , A61B2018/1407 , A61B2018/1435
摘要： A catheter assembly and method for treatment of cardiac arrhythmia, for example, atrial fibrillation, by electrically isolating a vessel, such as a pulmonary vein, from a chamber, such as the left atrium. The catheter assembly includes a catheter body and at least one electrode. The catheter body includes a proximal portion, an intermediate portion and a distal portion. The intermediate portion extends from the proximal portion and defines a longitudinal axis. The distal portion extends from the intermediate portion and forms a substantially closed loop transverse to the longitudinal axis. The at least one electrode is disposed along the loop. With this configuration, the loop is axially directed into contact with the chamber wall about the vessel ostium. Upon energization, the electrode ablates a continuous lesion pattern about the vessel ostium, thereby electrically isolating the vessel from the chamber.
摘要翻译：一种用于治疗心律失常（例如心房颤动）的导管组件和方法，通过诸如左心房的腔室电隔离血管（例如肺静脉）。导管组件包括导管主体和至少一个电极。导管主体包括近端部分，中间部分和远端部分。中间部分从近端部分延伸并且限定纵向轴线。远侧部分从中间部分延伸并且形成横向于纵向轴线的基本上闭合的环。沿着环设置至少一个电极。利用这种构造，环路被轴向地指向与容器孔周围的室壁接触。在通电时，电极消除围绕血管口的连续病变图案，从而将容器与腔室电隔离。

10. 发明授权

US5653740A Method and apparatus for induction of fibrillation 失效
标题翻译：用于诱发原纤维化的方法和装置
公开(公告)号：US5653740A
公开(公告)日：1997-08-05
申请号：US587309
申请日：1996-01-16
申请人： Paul J. Degroot , Rahul Mehra
发明人： Paul J. Degroot , Rahul Mehra
IPC分类号： A61N1/38
CPC分类号： A61N1/385
摘要： A method and apparatus for inducing fibrillation in a patient, for example to verify the efficacy of a defibrillator system. In the disclosed embodiment, an implantable cardioverter-defibrillator has an output stage coupled via a plurality of leads to the patient's heart. When it is desired to induce fibrillation in the patient, the device's control circuitry initiates an output capacitor charging cycle and subsequent delivery of a multi-phase fibrillation inducing stimulus to the heart. The multiple phases of the stimulus reflect an incremental discharging of the output capacitor. In one embodiment, the stimulus has three phases, with the first two separated by a time interval equal to or slightly less than the patient's "vulnerability window," which is defined as the time period following a paced cardiac event during which repolarization of the cardiac muscle is occurring, rendering the heart susceptible to induced fibrillation. The final phase of the multi-phase waveform reflects an untruncated discharge of the remaining energy on the output capacitor.
摘要翻译：一种用于在患者中诱导纤维性颤动的方法和装置，例如以验证除颤器系统的功效。在所公开的实施例中，植入式心律转复除颤器具有通过多条引线耦合到患者心脏的输出级。当期望在患者体内引起原纤维化时，该装置的控制电路启动输出电容器充电循环，并随后向心脏递送诱导多相纤颤的刺激。刺激的多个相位反映输出电容器的增量放电。在一个实施例中，刺激具有三个阶段，前两个时间间隔等于或略小于患者的“脆弱性窗口”，该时间间隔被定义为心脏事件复位后的心跳事件之后的时间段肌肉正在发生，使心脏易受诱发纤颤。多相波形的最后阶段反映出输出电容器上剩余能量的未经截断的放电。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式