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1. 发明授权

US08414573B2 Device and method for ablation of cardiac tissue 失效
标题翻译：心脏组织消融的装置和方法
公开(公告)号：US08414573B2
公开(公告)日：2013-04-09
申请号：US11545829
申请日：2006-10-11
申请人： David E. Francischelli
发明人： David E. Francischelli
IPC分类号： A61B18/18 , A61F7/00
CPC分类号： A61B18/1402 , A61B2018/00809 , A61B2018/1472
摘要： Methods for delivering precise amounts of fluid into cardiac tissue for the purpose of facilitating ablation of the tissue along a desired lesion line. One method injects fluid through a hollow needle. The injected fluid can be a highly conductive fluid injected in conjunction with radiofrequency ablation to create an ablative virtual electrode. The injected conductive fluid can provide deeper and narrower conduction paths and resulting lesions. Radiofrequency ablation can be performed at the same time as the fluid injection, using the injection device as an electrode, or subsequent to the fluid injection, using a separate device. In some methods, the injected fluid is a protective fluid, injected to protect tissue adjacent to the desired lesion line. Fluid delivery can be endocardial, epicardial, and epicardial on a beating heart. The present methods find one use in performing maze procedures to treat atrial fibrillation.
摘要翻译：用于将精确量的流体输送到心脏组织中以便于沿着期望的损伤线消融组织的方法。一种方法通过中空针头注入流体。注射的流体可以是与射频消融一起注入的高导电流体，以产生消融的虚拟电极。注射的导电流体可以提供更深和更窄的传导路径和所导致的损伤。射频消融可以在使用注射装置作为电极或在流体注射之后使用单独的装置与流体注射同时进行。在一些方法中，注射的流体是保护性流体，被注射以保护邻近所需病变线的组织。流体输送可以是搏动心脏的心内膜，心外膜和心外膜。本方法可用于进行迷宫手术来治疗房颤。

2. 发明申请

US20120277736A1 Method and Apparatus for Tissue Ablation 审中-公开
标题翻译：组织消融的方法和装置
公开(公告)号：US20120277736A1
公开(公告)日：2012-11-01
申请号：US13492466
申请日：2012-06-08
申请人： David E. Francischelli
发明人： David E. Francischelli
IPC分类号： A61B18/14 , A61B18/02 , A61B18/18
CPC分类号： A61B18/1445 , A61B18/1402 , A61B18/1442 , A61B2018/00994 , A61B2018/126 , A61B2018/1472
摘要： A method for ablation in which a portion of atrial tissue around the pulmonary veins of the heart is ablated by a first elongated ablation component and a second elongated ablation component movable relative to the first ablation component and having means for magnetically attracting the first and second components toward one another. The magnetic means draw the first and second components toward one another to compress the atrial tissue therebetween, along the length of the first and second components and thereby position the device for ablation of the tissue.
摘要翻译：一种消融方法，其中通过第一细长消融部件消除心脏周围的肺静脉周围的一部分心房组织，并且第二细长消融部件可相对于第一消融部件移动并且具有用于磁吸引第一和第二部件的装置朝向彼此磁性装置沿着第一和第二部件的长度将第一和第二部件彼此拉伸以压缩其间的心房组织，从而定位用于组织消融的装置。

3. 发明申请

US20110208054A1 ABLATION DEVICE AND METHOD FOR CREATING AN ELONGATE LESION USING SELECTIVELY ACTUATED TRANSDUCER CONTROLLED BY LESION COMPLETION SENSOR 审中-公开
标题翻译：使用通过LESION完成传感器控制的选择性致动传感器创建一个ELENATE LESION的消除装置和方法
公开(公告)号：US20110208054A1
公开(公告)日：2011-08-25
申请号：US12712613
申请日：2010-02-25
申请人： Mark T. Stewart , David E. Francischelli
发明人： Mark T. Stewart , David E. Francischelli
IPC分类号： A61B18/14 , A61B8/00
CPC分类号： A61N7/02 , A61B8/485 , A61B8/5223 , A61B2017/00106 , A61B2018/00577 , A61B2018/00839 , A61N2007/0065 , A61N2007/0095 , A61N2007/027
摘要： Device, system and method for evaluating the effectiveness of tissue ablations of a heart of a patient. The tissue is clamped between a pair of opposing jaws. A portion of the tissue is ablated at a first generally linear position on the tissue by applying ablative energy to two of a plurality of elongate electrodes, each of the two of the plurality of elongate electrodes being coupled in opposing relationship to each other and the pair of opposing jaws, respectively. An effectiveness of the ablation is sensed at a second generally linear position on the tissue with at least one of the plurality of elongate electrodes positioned on one of the pair of opposing jaws. The second linear position on the tissue is laterally distal to the first linear position on the tissue with respect to the atrium of the heart.
摘要翻译：用于评估患者心脏组织消融有效性的装置，系统和方法。将组织夹在一对相对的夹爪之间。通过向多个细长电极中的两个施加烧蚀能量，组织的一部分在组织上的第一大致线性位置被消融，多个细长电极中的每一个彼此相对地相互耦合，并且该对的对颚分别。在组织上的第二大致直线位置处感测消融的有效性，其中多个细长电极中的至少一个位于一对相对的夹爪中的一个上。组织上的第二线性位置相对于心脏的心房横向远离组织上的第一线性位置。

4. 发明授权

US07758580B2 Compound bipolar ablation device and method 失效
标题翻译：复合双极消融装置及方法
公开(公告)号：US07758580B2
公开(公告)日：2010-07-20
申请号：US11143400
申请日：2005-06-02
申请人： Paul T. Rothstein , Roderick E. Briscoe , David E. Francischelli , David J. S. Kim , Alison Lutterman
发明人： Paul T. Rothstein , Roderick E. Briscoe , David E. Francischelli , David J. S. Kim , Alison Lutterman
IPC分类号： A61B18/12
CPC分类号： A61B18/1442 , A61B2018/00363 , A61B2018/00375 , A61B2018/00577
摘要： Method and apparatus for ablating target tissue adjacent pulmonary veins of a patient. The ablation device can include a lower jaw assembly including a proximal jaw having a proximal electrode and a distal jaw having a distal electrode, and an upper jaw assembly including an upper jaw having an upper electrode. A proximal actuator can be movable between a first position in which the proximal jaw is open and a second position in which the proximal jaw is clamped with respect to the upper jaw. A distal actuator can be movable between a third position in which the distal jaw is open and a fourth position in which the distal jaw is clamped with respect to the upper jaw.
摘要翻译：用于消融患者的肺静脉附近的靶组织的方法和装置。消融装置可以包括下钳口组件，其包括具有近端电极的近端钳口和具有远端电极的远端钳口，以及包括具有上电极的上钳口的上钳口组件。近侧致动器可以在其中近端颚打开的第一位置和相对于上颚夹紧近端颌的第二位置之间移动。远端致动器可以在其中远侧钳口打开的第三位置和第二位置之间移动，在第四位置，远端钳口相对于上钳夹紧。

5. 发明授权

US07083620B2 Electrosurgical hemostat 有权
公开(公告)号：US07083620B2
公开(公告)日：2006-08-01
申请号：US10621893
申请日：2003-07-17
申请人： Scott E. Jahns , David E. Francischelli , Alison A. Lutterman , James R. Keogh , Roderick E. Briscoe , William G. O'Neill , Jack Goodman , Tom P. Daigle , Paul T. Rothstein , Adam A. Podbelski , Stephen J Roddy , David J. S. Kim , Mark R. Bilitz
发明人： Scott E. Jahns , David E. Francischelli , Alison A. Lutterman , James R. Keogh , Roderick E. Briscoe , William G. O'Neill , Jack Goodman , Tom P. Daigle , Paul T. Rothstein , Adam A. Podbelski , Stephen J Roddy , David J. S. Kim , Mark R. Bilitz
IPC分类号： A61B18/18 , A61B17/28
CPC分类号： A61B18/1445 , A61B2018/1861
摘要： A hemostat-type device for ablative treatment of tissue, particularly for treatment of atrial fibrillation, is constructed with features that provide easy and effective treatment. A swiveling head assembly can allow the jaws to be adjusted in pitch and roll. Malleable jaws can permit curved lesion shapes. A locking detent can secure the jaws in a closed position during the procedure. An illuminated indicator provides confirmation that the device is operating. A fluid delivery system simplifies irrigated ablation procedures.

6. 发明授权

US06916318B2 Variable length electrodes for delivery of irrigated ablation 有权
标题翻译：用于输送灌溉消融的可变长度电极
公开(公告)号：US06916318B2
公开(公告)日：2005-07-12
申请号：US10268816
申请日：2002-10-10
申请人： David E Francischelli , Richard H. Comben , Michael F Hoey , Rahul Mehra , Jon M. Ocel , Robert Pearson , Paul V. Trescony , Scott E. Jahns
发明人： David E Francischelli , Richard H. Comben , Michael F Hoey , Rahul Mehra , Jon M. Ocel , Robert Pearson , Paul V. Trescony , Scott E. Jahns
IPC分类号： A61B18/14 , A61B18/18
CPC分类号： A61B18/1492 , A61B18/1445 , A61B2018/00065 , A61B2018/00351 , A61B2018/00577 , A61B2018/1435 , A61B2018/1472 , A61B2218/002
摘要： A device for ablating tissue is provided. The device comprises a conductive element with a channel for irrigating fluid formed therein, which is in contact with a non-conductive microporous interface. All or a portion of the interface may be removable. When the interface is removed, a portion of the conductive element is exposed for use in ablating tissue. Methods of using the device and of removing the interface are also provided.
摘要翻译：提供了用于消融组织的装置。该装置包括导电元件，其具有用于在其中形成的冲洗流体的通道，其与非导电微孔界面接触。界面的全部或部分可以是可移动的。当界面被去除时，导电元件的一部分被暴露以用于消融组织。还提供了使用设备和移除界面的方法。

7. 发明授权

US09227088B2 Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions 有权
标题翻译：使用高强度聚焦超声波形成包含多个病变的消融组织区域的方法
公开(公告)号：US09227088B2
公开(公告)日：2016-01-05
申请号：US12772437
申请日：2010-05-03
申请人： James B. Hissong , Mark T. Stewart , David E. Francischelli , James R. Keough , James R. Skarda , Hotaik Lee , Nadine B. Smith
发明人： James B. Hissong , Mark T. Stewart , David E. Francischelli , James R. Keough , James R. Skarda , Hotaik Lee , Nadine B. Smith
IPC分类号： A61B5/05 , A61N7/02 , A61B19/00 , A61B18/00 , A61N7/00 , A61B8/00
CPC分类号： A61B17/320068 , A61B8/4281 , A61B34/20 , A61B2017/320076 , A61B2017/320078 , A61B2018/00291 , A61B2034/2051 , A61B2090/378 , A61B2090/3782 , A61N7/02 , A61N7/022 , A61N2007/0078
摘要： A device and method for ablating tissue is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding an ablating member within the patient while tracking the position of the ablating member in the patient, positioning the ablating member in a desired position to ablate tissue, emitting ablating energy from the ablating member to form an ablated tissue area and removing the ablating member from the patient.
摘要翻译：公开了一种用于消融组织的装置和方法，包括以下步骤：获取患者的解剖图像，将图像与患者相关联，在跟踪患者内的消融部件的位置的同时引导患者内的消融部件，定位消融成员在消融组织的期望位置，从烧蚀构件发出消融能量以形成消融的组织区域，并从患者身上移除消融部件。

8. 发明授权

US08512337B2 Method and system for treatment of atrial tachyarrhythmias 有权
标题翻译：治疗房性快速性心律失常的方法和系统
公开(公告)号：US08512337B2
公开(公告)日：2013-08-20
申请号：US10923073
申请日：2004-08-20
申请人： David E. Francischelli , Rahul Mehra
发明人： David E. Francischelli , Rahul Mehra
IPC分类号： A61B18/12
CPC分类号： A61B18/1445 , A61B18/1402 , A61B2017/2945 , A61B2018/00994 , A61B2018/126 , A61B2018/1432 , A61B2018/1472
摘要： A method of and a system for treatment of atrial tachyarrhythmias. The system includes a set of hemostats having elongated opposing jaws carrying mechanisms for applying ablation energy along the jaws. The jaws having straight and curved configurations selected to allow arrangement of the jaws of along opposite sides of walls of a patient's atrium. Treatment is accomplished by applying of ablation energy to the walls of a patient's artria to create lines of lesion corresponding generally to incisions employed in a Maze type procedure.
摘要翻译：一种治疗房性快速性心律失常的方法和系统。该系统包括一组具有延长的相对的夹爪的止血器，该钳口携带用于沿钳口施加消融能量的机构。钳口具有直的和弯曲的构造，其被选择为允许沿着病人心房的壁的相对侧布置钳口。通过将消融能量施加到患者的肌肉的壁上来实现治疗，以产生通常对于迷宫类型手术中使用的切口相应的损伤线。

9. 发明授权

US08221402B2 Method for guiding a medical device 有权
标题翻译：医疗器械引导方法
公开(公告)号：US08221402B2
公开(公告)日：2012-07-17
申请号：US11298282
申请日：2005-12-09
申请人： David E. Francischelli , James B. Hissong , James R. Keogh , James R. Skarda , Mark T. Stewart
发明人： David E. Francischelli , James B. Hissong , James R. Keogh , James R. Skarda , Mark T. Stewart
IPC分类号： A61B18/04 , A61B18/08
CPC分类号： A61N7/02 , A61B8/4272 , A61B18/1442 , A61B34/20 , A61B2017/00243 , A61B2018/00291 , A61B2034/2051 , A61B2034/2053 , A61B2034/2063 , A61B2090/378 , A61B2090/397 , A61N7/022 , A61N2007/0078
摘要： A device and method for ablating tissue is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding an ablating member within the patient while tracking the position of the ablating member in the patient, positioning the ablating member in a desired position to ablate tissue, emitting ablating energy from the ablating member to form an ablated tissue area and removing the ablating member from the patient.
摘要翻译：公开了一种用于消融组织的装置和方法，包括以下步骤：获取患者的解剖图像，将图像与患者相关联，在跟踪患者内的消融部件的位置的同时引导患者内的消融部件，定位消融成员在消融组织的期望位置，从烧蚀构件发出消融能量以形成消融的组织区域，并从患者身上移除消融部件。

10. 发明授权

US07959626B2 Transmural ablation systems and methods 有权
标题翻译：跨膜消融系统和方法
公开(公告)号：US07959626B2
公开(公告)日：2011-06-14
申请号：US11780911
申请日：2007-07-20
申请人： Jinback Hong , David E. Francischelli , Mark T. Stewart
发明人： Jinback Hong , David E. Francischelli , Mark T. Stewart
IPC分类号： A61B18/18
CPC分类号： A61B18/1206 , A61B5/053 , A61B5/7203 , A61B18/14 , A61B18/1442 , A61B2017/00092 , A61B2018/0016 , A61B2018/00351 , A61B2018/00363 , A61B2018/00577 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00761 , A61B2018/00791 , A61B2018/00875 , A61B2018/00886 , A61B2018/1467 , A61B2218/002
摘要： A method of applying ablation energy to achieve transmurality including applying ablation energy at a starting power to a tissue site and monitoring the impedance of the tissue site. The power applied to the tissue site can be increased in response to detection of a power plateau or application of a first power for a minimum time according to some embodiments. A power applied to the tissue site can be reduced in response to an increase in impedance according to some embodiments. Transmurality can be indicated in response to a transmurality plateau following a rise in impedance according to some embodiments.
摘要翻译：一种施加消融能量以实现透视性的方法，包括以起始功率对组织部位施加消融能量并监测组织部位的阻抗。根据一些实施例，施加到组织部位的功率可以响应于功率平台的检测或最小时间的应用而增加。根据一些实施例，响应于阻抗的增加，施加到组织部位的功率可以减小。根据一些实施例，可以响应于阻抗上升之后的透壁平台来指示透明度。

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