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1. 发明授权

US08058078B2 Device for automatically adjusting the bacterial inoculum level of a sample 有权
标题翻译：用于自动调节样品细菌接种量的装置
公开(公告)号：US08058078B2
公开(公告)日：2011-11-15
申请号：US13016040
申请日：2011-01-28
申请人： Timothy Hansen , Mark Anthony Messina , John Thuin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
发明人： Timothy Hansen , Mark Anthony Messina , John Thuin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
IPC分类号： G01N15/06 , G01N33/00 , G01N33/48
CPC分类号： G01N1/38 , C12M33/04 , G01N15/0205 , G01N35/0099 , G01N2035/00801 , G01N2035/1032 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： Various embodiments of the present invention provide, for example, a system and method for automatically adjusting the inoculum level of a sample. Certain embodiments of the present invention may measure a concentration of particles present in a preliminary sample using a sensor device and determine an amount of diluent to be added to or removed from a sample container to prepare a sample having a selected concentration of particles, corresponding to a selected inoculum level. Embodiments of the present invention may also automatically add or remove the diluent using an automated fluidics system so as to prepare a sample having the selected particle concentration. Once the selected particle concentration is achieved and verified, some embodiments may also remove at least a portion of the sample from the sample container such that the container contains a selected volume of the sample.
摘要翻译：本发明的各种实施例提供了例如用于自动调节样品的接种物水平的系统和方法。本发明的某些实施方案可以使用传感器装置测量存在于初步样品中的颗粒的浓度，并且确定要添加到样品容器中或从样品容器移除的稀释剂的量以制备具有选定浓度的颗粒的样品，对应于选择接种量。本发明的实施方案还可以使用自动化流体系统自动添加或除去稀释剂，以制备具有所选择的颗粒浓度的样品。一旦获得并验证所选择的颗粒浓度，一些实施方案也可以从样品容器中去除样品的至少一部分，使得容器含有所选择的样品体积。

2. 发明授权

US07901624B2 Device for automatically adjusting the bacterial inoculum level of a sample 有权
公开(公告)号：US07901624B2
公开(公告)日：2011-03-08
申请号：US11691662
申请日：2007-03-27
申请人： Timothy Roy Hansen , Mark Anthony Messina , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
发明人： Timothy Roy Hansen , Mark Anthony Messina , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
IPC分类号： G01N21/00 , G01N31/00 , G01N33/00
CPC分类号： G01N1/38 , C12M33/04 , G01N15/0205 , G01N35/0099 , G01N2035/00801 , G01N2035/1032 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： Various embodiments of the present invention provide, for example, a system and method for automatically adjusting the inoculum level of a sample. Certain embodiments of the present invention may measure a concentration of particles present in a preliminary sample using a sensor device and determine an amount of diluent to be added to or removed from a sample container to prepare a sample having a selected concentration of particles, corresponding to a selected inoculum level. Embodiments of the present invention may also automatically add or remove the diluent using an automated fluidics system so as to prepare a sample having the selected particle concentration. Once the selected particle concentration is achieved and verified, some embodiments may also remove at least a portion of the sample from the sample container such that the container contains a selected volume of the sample.

3. 发明申请

US20120031203A1 DEVICE FOR AUTOMATICALLY ADJUSTING THE BACTERIAL INOCULUM LEVEL OF A SAMPLE 有权
标题翻译：用于自动调节样品的细菌浓度的装置
公开(公告)号：US20120031203A1
公开(公告)日：2012-02-09
申请号：US13274788
申请日：2011-10-17
申请人： Timothy Roy Hansen , Mark Anthony Messina , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
发明人： Timothy Roy Hansen , Mark Anthony Messina , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
IPC分类号： G06F19/00
CPC分类号： G01N1/38 , C12M33/04 , G01N15/0205 , G01N35/0099 , G01N2035/00801 , G01N2035/1032 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： Various embodiments of the present invention provide, for example, a system and method for automatically adjusting the inoculum level of a sample. Certain embodiments of the present invention may measure a concentration of particles present in a preliminary sample using a sensor device and determine an amount of diluent to be added to or removed from a sample container to prepare a sample having a selected concentration of particles, corresponding to a selected inoculum level. Embodiments of the present invention may also automatically add or remove the diluent using an automated fluidics system so as to prepare a sample having the selected particle concentration. Once the selected particle concentration is achieved and verified, some embodiments may also remove at least a portion of the sample from the sample container such that the container contains a selected volume of the sample.
摘要翻译：本发明的各种实施例提供了例如用于自动调节样品的接种物水平的系统和方法。本发明的某些实施方案可以使用传感器装置测量存在于初步样品中的颗粒的浓度，并且确定要添加到样品容器中或从样品容器移除的稀释剂的量以制备具有选定浓度的颗粒的样品，对应于选择接种量。本发明的实施方案还可以使用自动化流体系统自动添加或除去稀释剂，以制备具有所选择的颗粒浓度的样品。一旦获得并验证所选择的颗粒浓度，一些实施方案也可以从样品容器中去除样品的至少一部分，使得容器含有所选择的样品体积。

4. 发明授权

US08478445B2 Device for automatically adjusting the bacterial inoculum level of a sample 有权
标题翻译：用于自动调节样品细菌接种量的装置
公开(公告)号：US08478445B2
公开(公告)日：2013-07-02
申请号：US13274788
申请日：2011-10-17
申请人： Timothy Roy Hansen , Mark Anthony Messina , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
发明人： Timothy Roy Hansen , Mark Anthony Messina , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
IPC分类号： G01N15/06 , G01N33/00 , G01N33/48
CPC分类号： G01N1/38 , C12M33/04 , G01N15/0205 , G01N35/0099 , G01N2035/00801 , G01N2035/1032 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： Various embodiments of the present invention provide, for example, a system and method for automatically adjusting the inoculum level of a sample. Certain embodiments of the present invention may measure a concentration of particles present in a preliminary sample using a sensor device and determine an amount of diluent to be added to or removed from a sample container to prepare a sample having a selected concentration of particles, corresponding to a selected inoculum level. Embodiments of the present invention may also automatically add or remove the diluent using an automated fluidics system so as to prepare a sample having the selected particle concentration. Once the selected particle concentration is achieved and verified, some embodiments may also remove at least a portion of the sample from the sample container such that the container contains a selected volume of the sample.
摘要翻译：本发明的各种实施例提供了例如用于自动调节样品的接种物水平的系统和方法。本发明的某些实施方案可以使用传感器装置测量存在于初步样品中的颗粒的浓度，并且确定要添加到样品容器中或从样品容器移除的稀释剂的量以制备具有选定浓度的颗粒的样品，对应于选择接种量。本发明的实施方案还可以使用自动化流体系统自动添加或除去稀释剂，以制备具有所选择的颗粒浓度的样品。一旦获得并验证所选择的颗粒浓度，一些实施方案也可以从样品容器中去除样品的至少一部分，使得容器含有所选择的样品体积。

5. 发明申请

US20110123975A1 DEVICE FOR AUTOMATICALLY ADJUSTING THE BACTERIAL INOCULUM LEVEL OF A SAMPLE 有权
标题翻译：用于自动调节样品的细菌浓度的装置
公开(公告)号：US20110123975A1
公开(公告)日：2011-05-26
申请号：US13016040
申请日：2011-01-28
申请人： Timothy Roy Hansen , Mark Anthony Messina , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
发明人： Timothy Roy Hansen , Mark Anthony Messina , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
IPC分类号： C12Q3/00 , G06F19/00
CPC分类号： G01N1/38 , C12M33/04 , G01N15/0205 , G01N35/0099 , G01N2035/00801 , G01N2035/1032 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： Various embodiments of the present invention provide, for example, a system and method for automatically adjusting the inoculum level of a sample. Certain embodiments of the present invention may measure a concentration of particles present in a preliminary sample using a sensor device and determine an amount of diluent to be added to or removed from a sample container to prepare a sample having a selected concentration of particles, corresponding to a selected inoculum level. Embodiments of the present invention may also automatically add or remove the diluent using an automated fluidics system so as to prepare a sample having the selected particle concentration. Once the selected particle concentration is achieved and verified, some embodiments may also remove at least a portion of the sample from the sample container such that the container contains a selected volume of the sample.
摘要翻译：本发明的各种实施例提供了例如用于自动调节样品的接种物水平的系统和方法。本发明的某些实施方案可以使用传感器装置测量存在于初步样品中的颗粒的浓度，并且确定要添加到样品容器中或从样品容器移除的稀释剂的量以制备具有选定浓度的颗粒的样品，对应于选择接种量。本发明的实施方案还可以使用自动化流体系统自动添加或除去稀释剂，以制备具有所选择的颗粒浓度的样品。一旦获得并验证所选择的颗粒浓度，一些实施方案也可以从样品容器中去除样品的至少一部分，使得容器含有所选择的样品体积。

6. 发明申请

US20080072664A1 DEVICE FOR AUTOMATICALLY ADJUSTING THE BACTERIAL INOCULUM LEVEL OF A SAMPLE 有权
标题翻译：用于自动调节样品的细菌浓度的装置
公开(公告)号：US20080072664A1
公开(公告)日：2008-03-27
申请号：US11691662
申请日：2007-03-27
申请人： Timothy Roy Hansen , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
发明人： Timothy Roy Hansen , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
IPC分类号： G01N1/38 , B01L11/00 , G06F17/00
CPC分类号： G01N1/38 , C12M33/04 , G01N15/0205 , G01N35/0099 , G01N2035/00801 , G01N2035/1032 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： Various embodiments of the present invention provide, for example, a system and method for automatically adjusting the inoculum level of a sample. Certain embodiments of the present invention may measure a concentration of particles present in a preliminary sample using a sensor device and determine an amount of diluent to be added to or removed from a sample container to prepare a sample having a selected concentration of particles, corresponding to a selected inoculum level. Embodiments of the present invention may also automatically add or remove the diluent using an automated fluidics system so as to prepare a sample having the selected particle concentration. Once the selected particle concentration is achieved and verified, some embodiments may also remove at least a portion of the sample from the sample container such that the container contains a selected volume of the sample.
摘要翻译：本发明的各种实施例提供了例如用于自动调节样品的接种物水平的系统和方法。本发明的某些实施方案可以使用传感器装置测量存在于初步样品中的颗粒的浓度，并且确定要添加到样品容器中或从样品容器移除的稀释剂的量以制备具有选定浓度的颗粒的样品，对应于选择接种量。本发明的实施方案还可以使用自动化流体系统自动添加或除去稀释剂，以制备具有所选择的颗粒浓度的样品。一旦获得并验证所选择的颗粒浓度，一些实施方案也可以从样品容器中去除样品的至少一部分，使得容器含有所选择的样品体积。

7. 发明授权

US09545632B2 Pierceable cap 有权
标题翻译：可穿帽子
公开(公告)号：US09545632B2
公开(公告)日：2017-01-17
申请号：US13985177
申请日：2012-02-14
申请人： Ammon David Lentz , Kevin Bailey , Dustin Diemert , Joel Daniel Krayer , Laurence Michael Vaughan
发明人： Ammon David Lentz , Kevin Bailey , Dustin Diemert , Joel Daniel Krayer , Laurence Michael Vaughan
IPC分类号： B01L3/00 , B65D51/00
CPC分类号： B01L3/56 , B65D51/002 , B65D2231/022 , Y10T436/2575
摘要： A pierceable cap 11 may be used for containing sample specimens. The pierceable cap 11 may prevent escape of sample specimens before transfer with a transfer device 43. The pierceable cap 11 may fit over a vessel 21. An access port in the shell of the pierceable cap 11 may allow passage of a transfer device 43 through the pierceable cap 11. At least one frangible layer 215, 216 may be configured with cross slits 506 in a particular cross slit geometry. The cross slits 506 may contain an openable portion 644 or be covered by a thin membrane 645. The shell 610 and frangible layer (s) 215, 216 may be integrated into a one piece cap 601, or be separate components 634. The membrane on which the cross slits 506 are placed can be flat or contoured to guide the transfer device 43 to the cross slits 506.
摘要翻译：可以使用可刺破盖11来容纳样品。可穿透盖11可以在与转运装置43转移之前防止样品标本脱离。可刺破盖11可以装配在容器21上。可刺穿盖11的壳体中的进入口可以允许传送装置43通过至少一个易碎层215,216可以被构造成具有特定交叉缝隙几何形状的交叉狭缝506。交叉狭缝506可以包含可打开部分644或被薄膜645覆盖。壳体610和易碎层215,216可以集成到单件盖601中，或者是分离的部件634。交叉狭缝506的位置可以是平坦的或轮廓的，以将传送装置43引导到十字狭缝506。

8. 发明申请

US20140011292A1 PIERCEABLE CAP 有权
标题翻译：宝贵的帽子
公开(公告)号：US20140011292A1
公开(公告)日：2014-01-09
申请号：US13985177
申请日：2012-02-14
申请人： Ammon David Lentz , Kevin Bailey , Dustin Diemert , Joel Daniel Krayer , Laurence Michael Vaughan
发明人： Ammon David Lentz , Kevin Bailey , Dustin Diemert , Joel Daniel Krayer , Laurence Michael Vaughan
IPC分类号： B01L3/00
CPC分类号： B01L3/56 , B65D51/002 , B65D2231/022 , Y10T436/2575
摘要： A pierceable cap 11 may be used for containing sample specimens. The pierceable cap 11 may prevent escape of sample specimens before transfer with a transfer device 43. The pierceable cap 11 may fit over a vessel 21. An access port in the shell of the pierceable cap 11 may allow passage of a transfer device 43 through the pierceable cap 11. At least one frangible layer 215, 216 may be configured with cross slits 506 in a particular cross slit geometry. The cross slits 506 may contain an openable portion 644 or be covered by a thin membrane 645. The shell 610 and frangible layer (s) 215, 216 may be integrated into a one piece cap 601, or be separate components 634. The membrane on which the cross slits 506 are placed can be flat or contoured to guide the transfer device 43 to the cross slits 506.
摘要翻译：可以使用可刺破盖11来容纳样品。可穿透盖11可以在与转运装置43转移之前防止样品标本脱离。可刺破盖11可以装配在容器21上。可刺穿盖11的壳体中的进入口可以允许传送装置43通过至少一个易碎层215,216可以被构造成具有特定交叉缝隙几何形状的交叉狭缝506。交叉狭缝506可以包含可打开部分644或被薄膜645覆盖。壳体610和易碎层215,216可以集成到单件盖601中，或者是分离的部件634。交叉狭缝506的位置可以是平坦的或轮廓的，以将传送装置43引导到十字狭缝506。

9. 外观设计

USD692162S1 Single piece reagent holder 有权
公开(公告)号：USD692162S1
公开(公告)日：2013-10-22
申请号：US29403131
申请日：2011-09-30
申请人： Ammon David Lentz , Richard St-Pierre , Dwight Livingston , Adam Bruce Steel
设计人： Ammon David Lentz , Richard St-Pierre , Dwight Livingston , Adam Bruce Steel

10. 发明授权

US08387811B2 Pierceable cap having piercing extensions 有权
标题翻译：具有穿孔延伸的可穿戴帽
公开(公告)号：US08387811B2
公开(公告)日：2013-03-05
申请号：US11979713
申请日：2007-11-07
申请人： Dwight Livingston , Dustin Diemert , Ammon David Lentz
发明人： Dwight Livingston , Dustin Diemert , Ammon David Lentz
IPC分类号： B65D41/50 , B65D41/32 , B65D41/20 , B01L3/00 , A61J1/05
CPC分类号： B65D51/224 , B01L3/50825 , B01L2300/044 , B01L2300/0672 , B65D51/002 , B65D51/185
摘要： A pierceable cap maybe used for containing sample specimens during storage and transport. The pierceable cap may prevent unwanted escape of sample specimen before transfer with a transfer device. The pierceable cap may fit over a vessel. An access port in the pierceable cap may allow passage of a tip of a transfer device though the pierceable cap. Multiple frangible layers maybe disposed across the access port. One or more extensions proximate to a lower frangible layer may rotate around one or more coupling regions during insertion of the transfer device. The movement of the one or more extensions may pierce the lower frangible layer to create airways and allow air to escape from a vessel at a reduced velocity. Upper frangible layers may prevent escape of materials from spaces intermediate between the lower frangible layer and the upper frangible layers.
摘要翻译：在可储存和运输过程中，可以使用可刺破的盖子来容纳样品。可穿透帽可以防止在用传送装置转移之前样品样品的不必要的逸出。可刺破的帽可以装在船上。可穿透帽中的进入口可以允许传送装置的尖端通过可刺穿的帽。多个易碎层可以跨越接入端口设置。靠近下部易碎层的一个或多个延伸部可以在插入传送装置期间围绕一个或多个耦合区域旋转。一个或多个延伸部的运动可以刺穿下部易碎层以产生气道并允许空气以较低的速度从容器中逸出。上部易碎层可以防止材料从较低易碎层和上部脆性层之间的空间中逸出。

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