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1. 发明授权

US07867271B2 Rapid-exchange delivery systems for self-expanding stents 有权
标题翻译：用于自扩张支架的快速交换输送系统
公开(公告)号：US07867271B2
公开(公告)日：2011-01-11
申请号：US10720032
申请日：2003-11-20
申请人： Timothy A. Geiser , Charles R. Peterson , Andy Denison , Stephanie Klocke , Samir Patel , Joanna Lubas , Joanne Lumauig , Kathy Lind , Keif Fitzgerald
发明人： Timothy A. Geiser , Charles R. Peterson , Andy Denison , Stephanie Klocke , Samir Patel , Joanna Lubas , Joanne Lumauig , Kathy Lind , Keif Fitzgerald
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/966 , A61M2025/0183
摘要： A catheter assembly is provided having an inner member and an outer member extending along a longitudinal axis, the inner member and the outer member having a coaxial configuration and dimensioned for relative axial movement. The outer member may include an anti rotation member adapted to engage with a longitudinal slot formed on the inner member so as to maintain rotational alignment between inner member and outer member. The inner member can be made with a proximal portion made from a tubing such as hypotubing or a coil tubing. The inner member also may be made with a proximal portion made with a support mandrel. A coil tubing can be utilized to form the guide wire receiving member which is attached to the inner member.
摘要翻译：提供导管组件，其具有内部构件和沿着纵向轴线延伸的外部构件，内部构件和外部构件具有同轴构造并且被设计成用于相对轴向移动。外部构件可以包括防旋转构件，其适于与形成在内部构件上的纵向狭槽接合，以便保持内部构件和外部构件之间的旋转对准。内部构件可以由具有诸如假面或管线管的管子制成的近端部分制成。内部构件也可以由具有支撑心轴的近端部分制成。可以使用线圈管来形成附接到内部构件的导丝接收构件。

2. 发明申请

US20050113902A1 Rapid-exchange delivery systems for self-expanding stents 有权
标题翻译：用于自扩张支架的快速交换输送系统
公开(公告)号：US20050113902A1
公开(公告)日：2005-05-26
申请号：US10720032
申请日：2003-11-20
申请人： Timothy Geiser , Charles Peterson , Andy Denison , Stephanie Klocke , Samir Patel , Joanna Lubas , Joanne Lumauig , Kathy Lind , Keif Fitzgerald
发明人： Timothy Geiser , Charles Peterson , Andy Denison , Stephanie Klocke , Samir Patel , Joanna Lubas , Joanne Lumauig , Kathy Lind , Keif Fitzgerald
IPC分类号： A61F2/84 , A61L29/00 , A61M25/00 , A61F2/06
CPC分类号： A61F2/95 , A61F2/966 , A61M2025/0183
摘要： A catheter assembly is provided having an inner member and an outer member extending along a longitudinal axis, the inner member and the outer member having a coaxial configuration and dimensioned for relative axial movement. The outer member may include an anti rotation member adapted to engage with a longitudinal slot formed on the inner member so as to maintain rotational alignment between inner member and outer member. The inner member can be made with a proximal portion made from a tubing such as hypotubing or a coil tubing. The inner member also may be made with a proximal portion made with a support mandrel. A coil tubing can be utilized to form the guide wire receiving member which is attached to the inner member.
摘要翻译：提供导管组件，其具有内部构件和沿着纵向轴线延伸的外部构件，内部构件和外部构件具有同轴构造并且被设计成用于相对轴向移动。外部构件可以包括防旋转构件，其适于与形成在内部构件上的纵向狭槽接合，以便保持内部构件和外部构件之间的旋转对准。内部构件可以由具有诸如假面或管线管的管子制成的近端部分制成。内部构件也可以由具有支撑心轴的近端部分制成。可以使用线圈管来形成附接到内部构件的导丝接收构件。

3. 发明授权

US07776080B2 Stent delivery catheter system and method of implanting a self-expanding stent with embolic protection 有权
标题翻译：支架输送导管系统和植入具有栓塞保护的自扩张支架的方法
公开(公告)号：US07776080B2
公开(公告)日：2010-08-17
申请号：US11739743
申请日：2007-04-25
申请人： Nianjiong Joan Bei , Keif Fitzgerald , Patrick C. Saxton , Zhicheng Lin , Steven A. Tyler , Joanna Lubas
发明人： Nianjiong Joan Bei , Keif Fitzgerald , Patrick C. Saxton , Zhicheng Lin , Steven A. Tyler , Joanna Lubas
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2002/9583 , A61F2230/0006 , A61F2230/008
摘要： A catheter system and method for implanting an endoprosthesis such as a stent at a treatment site in a patient's body lumen. The catheter provides a complete system for stent delivery, dilatation, and delivery and/or recovery of an expandable device, such as an embolic protection device, adjacent to the treatment site in the body lumen.
摘要翻译：用于在患者体腔内的治疗部位植入诸如支架的内假体的导管系统和方法。该导管提供了用于支架输送，扩张，以及邻近体腔内治疗部位的可扩张装置（例如栓塞保护装置）的递送和/或回收的完整系统。

4. 发明申请

US20100331951A1 STENT DELIVERY CATHETER SYSTEM AND METHOD OF IMPLANTING A SELF-EXPANDING STENT WITH EMBOLIC PROTECTION 有权
标题翻译： STENT传送导管系统及其自动伸展手柄的嵌入式保护方法
公开(公告)号：US20100331951A1
公开(公告)日：2010-12-30
申请号：US12857467
申请日：2010-08-16
申请人： Nianjiong Joan Bei , Keif Fitzgerald , Patrick C. Saxton , Zhicheng Lin , Steven A. Tyler , Joanna Lubas
发明人： Nianjiong Joan Bei , Keif Fitzgerald , Patrick C. Saxton , Zhicheng Lin , Steven A. Tyler , Joanna Lubas
IPC分类号： A61F2/82 , A61M29/00
CPC分类号： A61F2/958 , A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2002/9583 , A61F2230/0006 , A61F2230/008
摘要： A catheter system and method for implanting an endoprosthesis such as a stent at a treatment site in a patient's body lumen. The catheter provides a complete system for stent delivery, dilatation, and delivery and/or recovery of an expandable device, such as an embolic protection device, adjacent to the treatment site in the body lumen.
摘要翻译：用于在患者体腔内的治疗部位植入诸如支架的内假体的导管系统和方法。该导管提供了用于支架输送，扩张，以及邻近体腔内治疗部位的可扩张装置（例如栓塞保护装置）的递送和/或回收的完整系统。

5. 发明授权

US08323327B2 Stent delivery catheter system and method of implanting a self-expanding stent with embolic protection 有权
标题翻译：支架输送导管系统和植入具有栓塞保护的自扩张支架的方法
公开(公告)号：US08323327B2
公开(公告)日：2012-12-04
申请号：US12857467
申请日：2010-08-16
申请人： Nianjiong Joan Bei , Keif Fitzgerald , Patrick C. Saxton , Zhicheng Lin , Steven A. Tyler , Joanna Lubas
发明人： Nianjiong Joan Bei , Keif Fitzgerald , Patrick C. Saxton , Zhicheng Lin , Steven A. Tyler , Joanna Lubas
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2002/9583 , A61F2230/0006 , A61F2230/008
摘要： A catheter system for implanting an endoprosthesis at a treatment site in a patient's body lumen. The catheter includes an elongated shaft outer member and a stent sheath distal portion and a self-expanding stent radially restrained in a collapsed configuration within the stent sheath distal portion. A balloon catheter dimensioned for relative axial movement within the shaft outer member has an elongated shaft having an inflation lumen and a device receiving lumen. A stent stop secured to the balloon catheter is reversibly radially expandable to deploy from a collapsed to a radially expanded configuration. In the expanded configuration, the stent stop prevents longitudinal displacement of the stent. A balloon is located on a distal shaft section is releasably locked with respect to the shaft outer member and slidably disposed therein in an unlocked configuration.
摘要翻译：一种用于在患者体腔内的治疗部位植入内假体的导管系统。导管包括细长轴外部构件和支架护套远端部分以及在扩张器护套远端部分中以收缩构型径向约束的自扩张支架。用于在轴外部构件内进行相对轴向移动的气囊导管具有细长轴，该细长轴具有充气腔和容纳腔的装置。固定到气囊导管的支架止动器可逆地径向展开，从展开状态展开到径向展开的构型。在扩张结构中，支架止动件防止支架的纵向位移。位于远侧轴部上的气囊相对于轴外部构件可释放地锁定并且以可解锁的构造可滑动地设置在其中。

6. 发明申请

US20080269868A1 STENT DELIVERY CATHETER SYSTEM AND METHOD OF IMPLANTING A SELF-EXPANDING STENT WITH EMBOLIC PROTECTION 有权
标题翻译： STENT传送导管系统及其自动伸展手柄的嵌入式保护方法
公开(公告)号：US20080269868A1
公开(公告)日：2008-10-30
申请号：US11739743
申请日：2007-04-25
申请人： Nianjiong Joan Bei , Keif Fitzgerald , Patrick C. Saxton , Zhicheng Lin , Steven A. Tyler , Joanna Lubas
发明人： Nianjiong Joan Bei , Keif Fitzgerald , Patrick C. Saxton , Zhicheng Lin , Steven A. Tyler , Joanna Lubas
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2002/9583 , A61F2230/0006 , A61F2230/008
摘要： A catheter system and method for implanting an i such as a stent at a treatment site in a patient's body lumen. The catheter provides a complete system for stent delivery, dilatation, and delivery and/or recovery of an expandable device, such as an embolic protection device, adjacent to the treatment site in the body lumen.
摘要翻译：用于在患者体腔内的治疗部位植入诸如支架的i的导管系统和方法。该导管提供了用于支架输送，扩张，以及邻近体腔内治疗部位的可扩张装置（例如栓塞保护装置）的递送和/或回收的完整系统。

7. 发明申请

US20070055342A1 Delivery system for medical devices 审中-公开
标题翻译：医疗器械输送系统
公开(公告)号：US20070055342A1
公开(公告)日：2007-03-08
申请号：US11580431
申请日：2006-10-13
申请人： Patrick Wu , Keif Fitzgerald , Stephanie Klocke
发明人： Patrick Wu , Keif Fitzgerald , Stephanie Klocke
IPC分类号： A61F2/06
CPC分类号： A61M25/0023 , A61F2/95 , A61F2/966 , A61F2002/9517 , A61M25/0021 , A61M2025/006 , A61M2025/0062 , A61M2025/0098 , A61M2025/0183 , A61M2025/0681
摘要： The invention is directed to a delivery system for implantation a self-expanding medical device in a body which includes a control handle and a catheter portion. The catheter portion includes an outer restraining member which covers the collapsed, medical device, an inner catheter member having a distal end including a region upon which the medical device is mounted, and an outer sheath which is removably attached to the control handle. The outer sheath creates a conduit for the catheter portion to prevent the inner catheter member from moving axially when the outer restraining member is retracted. The control handle has a rotatable thumbwheel to actuate a retraction mechanism attached to the proximal end of the outer restraining member which moves the restraining member in a proximal direction to deploy the medical device.
摘要翻译：本发明涉及一种用于将自扩张医疗装置植入体内的递送系统，其包括控制手柄和导管部分。所述导管部分包括覆盖所述收缩的医疗装置的外限制构件，具有包括安装所述医疗装置的区域的远端的内导管构件和可移除地附接到所述控制手柄的外护套。当外部限制构件缩回时，外护套产生用于导管部分的导管，以防止内部导管构件轴向移动。控制手柄具有可旋转的指轮，以致动附接到外约束构件的近端的缩回机构，该缩回机构沿约束方向移动约束构件以展开医疗装置。

8. 发明申请

US20050090890A1 Delivery system for medical devices 有权
标题翻译：医疗器械输送系统
公开(公告)号：US20050090890A1
公开(公告)日：2005-04-28
申请号：US10946944
申请日：2004-09-22
申请人： Patrick Wu , Keif Fitzgerald , Stephanie Klocke
发明人： Patrick Wu , Keif Fitzgerald , Stephanie Klocke
IPC分类号： A61F2/06 , A61F2/84 , A61F11/00 , A61M29/00
CPC分类号： A61M25/0023 , A61F2/95 , A61F2/966 , A61F2002/9517 , A61M25/0021 , A61M2025/006 , A61M2025/0062 , A61M2025/0098 , A61M2025/0183 , A61M2025/0681
摘要： The invention is directed to a delivery system for implantation a self-expanding medical device in a body which includes a control handle and a catheter portion. The catheter portion includes an outer restraining member which covers the collapsed, medical device, an inner catheter member having a distal end including a region upon which the medical device is mounted, and an outer sheath which is removably attached to the control handle. The outer sheath creates a conduit for the catheter portion to prevent the inner catheter member from moving axially when the outer restraining member is retracted. The control handle has a rotatable thumbwheel to actuate a retraction mechanism attached to the proximal end of the outer restraining member which moves the restraining member in a proximal direction to deploy the medical device.
摘要翻译：本发明涉及一种用于将自扩张医疗装置植入体内的递送系统，其包括控制手柄和导管部分。所述导管部分包括覆盖所述收缩的医疗装置的外限制构件，具有包括安装所述医疗装置的区域的远端的内导管构件和可移除地附接到所述控制手柄的外护套。当外部限制构件缩回时，外护套产生用于导管部分的导管，以防止内部导管构件轴向移动。控制手柄具有可旋转的指轮，以致动附接到外约束构件的近端的缩回机构，该缩回机构沿约束方向移动约束构件以展开医疗装置。

9. 发明授权

US07993384B2 Delivery system for medical devices 有权
标题翻译：医疗器械输送系统
公开(公告)号：US07993384B2
公开(公告)日：2011-08-09
申请号：US10946944
申请日：2004-09-22
申请人： Patrick P. Wu , Keif Fitzgerald , Stephanie Klocke
发明人： Patrick P. Wu , Keif Fitzgerald , Stephanie Klocke
IPC分类号： A61F2/82
CPC分类号： A61M25/0023 , A61F2/95 , A61F2/966 , A61F2002/9517 , A61M25/0021 , A61M2025/006 , A61M2025/0062 , A61M2025/0098 , A61M2025/0183 , A61M2025/0681
摘要： The invention is directed to a delivery system for implantation a self-expanding medical device in a body which includes a control handle and a catheter portion. The catheter portion includes an outer restraining member which covers the collapsed, medical device, an inner catheter member having a distal end including a region upon which the medical device is mounted, and an outer sheath which is removably attached to the control handle. The outer sheath creates a conduit for the catheter portion to prevent the inner catheter member from moving axially when the outer restraining member is retracted. The control handle has a rotatable thumbwheel to actuate a retraction mechanism attached to the proximal end of the outer restraining member which moves the restraining member in a proximal direction to deploy the medical device.
摘要翻译：本发明涉及一种用于将自扩张医疗装置植入体内的递送系统，其包括控制手柄和导管部分。所述导管部分包括覆盖所述收缩的医疗装置的外限制构件，具有包括安装所述医疗装置的区域的远端的内导管构件和可移除地附接到所述控制手柄的外护套。当外部限制构件缩回时，外护套产生用于导管部分的导管，以防止内部导管构件轴向移动。控制手柄具有可旋转的指轮，以致动附接到外约束构件的近端的缩回机构，该缩回机构沿约束方向移动约束构件以展开医疗装置。

10. 发明授权

US08974514B2 Intravascular stent with integrated link and ring strut 有权
标题翻译：具有集成连杆和环支柱的血管内支架
公开(公告)号：US08974514B2
公开(公告)日：2015-03-10
申请号：US11724089
申请日：2007-03-13
申请人： Boris Anukhin , Hao-Ming Hsiao , Keif Fitzgerald
发明人： Boris Anukhin , Hao-Ming Hsiao , Keif Fitzgerald
IPC分类号： A61F2/06 , A61F2/915
CPC分类号： A61F2/915 , A61F2002/91541 , A61F2002/91583 , A61F2230/0054 , A61F2250/0036
摘要： An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The stent includes a plurality of rings connected by links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. The stent can be compressed or crimped onto a catheter to a very low profile since links are integrally formed from a portion of the struts forming the rings. The stent is constructed so that the cylindrical rings are very close together in order to provide maximum scaffolding, and if the stent has a drug coating, to provide a uniform drug delivery over the length of the stent. The connecting links are integrally formed from a portion of the struts forming the rings so that the links can have a maximum length thereby providing increased longitudinal flexibility of the stent.
摘要翻译：可扩张支架植入体腔，例如冠状动脉，外周动脉或其他体腔。支架包括通过连杆连接的多个环。支架在纵向具有高度的柔性，但具有足够的容器壁覆盖和径向强度足以保持打开动脉或其他体腔。支架可以被压缩或卷曲到导管上以非常低的轮廓，因为连杆由形成环的支柱的一部分整体形成。支架被构造成使得圆柱形环非常靠近在一起以便提供最大的脚手架，并且如果支架具有药物涂层，以在支架的长度上提供均匀的药物递送。连接连杆由形成环的支柱的一部分整体形成，使得连杆可以具有最大长度，从而提供支架的增加的纵向柔性。

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