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1. 发明申请

US20120116496A1 STENT STRUCTURES FOR USE WITH VALVE REPLACEMENTS 审中-公开
标题翻译：使用阀门更换的STENT结构
公开(公告)号：US20120116496A1
公开(公告)日：2012-05-10
申请号：US13286407
申请日：2011-11-01
申请人： Timothy A. Chuter , Blayne A. Roeder , Sharath Gopalakrishnamurthy , Alan R. Leewood
发明人： Timothy A. Chuter , Blayne A. Roeder , Sharath Gopalakrishnamurthy , Alan R. Leewood
IPC分类号： A61F2/82
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2220/0016 , A61F2230/0019 , A61F2230/0078
摘要： The present embodiments provide a medical device for implantation in a patient comprising a stent and a valve. The stent comprises a proximal region comprising a cylindrical shape having a first outer diameter in an expanded state, and a distal region comprising a cylindrical shape having a second outer diameter in the expanded state. The second outer diameter is greater than the first outer diameter. A proximal region of the valve is at least partially positioned within the proximal region of the stent, and the distal region of the valve is at least partially positioned within one of tapered and distal regions of the stent. When implanted, the proximal region of the stent and the proximal region of the valve are aligned with a native valve, and the distal region of the valve is distally spaced-apart from the native valve.
摘要翻译：本实施例提供了用于植入患者的医疗装置，其包括支架和阀。所述支架包括近端区域，所述近端区域包括具有处于展开状态的第一外径的圆柱形形状，以及远侧区域，所述远端区域包括处于展开状态的具有第二外径的圆柱形形状。第二外径大于第一外径。瓣膜的近端区域至少部分地定位在支架的近侧区域内，并且瓣膜的远端区域至少部分地定位在支架的锥形和远端区域之一内。当植入时，支架的近端区域和瓣膜的近侧区域与天然瓣膜对准，并且瓣膜的远端区域与天然瓣膜远离间隔开。

2. 发明授权

US08574284B2 Low profile non-symmetrical bare alignment stents with graft 有权
标题翻译：薄型非对称裸定位支架与移植物
公开(公告)号：US08574284B2
公开(公告)日：2013-11-05
申请号：US12472082
申请日：2009-05-26
申请人： Blayne A. Roeder , Jarin Kratzberg , William K. Dierking , Erik E. Rasmussen , Bent Oehlenschlaeger , Kim Mogelvang Jensen , David Brocker , Alan R. Leewood , Timothy A. Chuter , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew S. Huser
发明人： Blayne A. Roeder , Jarin Kratzberg , William K. Dierking , Erik E. Rasmussen , Bent Oehlenschlaeger , Kim Mogelvang Jensen , David Brocker , Alan R. Leewood , Timothy A. Chuter , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew S. Huser
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/856 , A61F2/86 , A61F2/89 , A61F2/915 , A61F2002/065 , A61F2002/075 , A61F2002/8486 , A61F2002/91516 , A61F2002/91558 , A61F2210/0014 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/0013 , A61F2230/005 , A61F2230/0054 , A61F2230/0067
摘要： A stent graft for use in a medical procedure to treat a dissection of a patient's ascending thoracic aorta. The stent graft includes bare alignment stents at least at a proximal end, and often with a stent at both ends, each stent having opposing sets of curved apices, where the curved section of one broader set of apices has a radius of curvature that is greater than the curved section of the other narrower set of apices. The proximal stent is flared in a manner such that its broad apices occupy a larger circumference around the stent than do its narrower apices, where this flared feature provides for anchoring engagement near the aortic root in a manner not interfering with the coronary arteries or the aortic valve.
摘要翻译：用于医疗手术中用于治疗患者升胸胸主动脉解剖的支架移植物。支架移植物至少在近端处包括裸定位支架，并且通常在两端具有支架，每个支架具有相对的一组弯曲顶点，其中一组较宽的顶点的弯曲部分具有更大的曲率半径比其他较窄的顶点的弯曲部分。近端支架以这样的方式展开，使得其宽顶点在支架周围占据比其较窄的顶点更大的圆周，其中该扩张特征以不干扰冠状动脉或主动脉的方式提供主动脉根部附近的锚定接合阀。

3. 发明申请

US20120116498A1 AORTIC VALVE PROSTHESES 审中-公开
标题翻译：主动阀出现
公开(公告)号：US20120116498A1
公开(公告)日：2012-05-10
申请号：US13286416
申请日：2011-11-01
申请人： Timothy A. Chuter , Blayne A. Roeder , Sharath Gopalakrishnamurthy , Alan R. Leewood
发明人： Timothy A. Chuter , Blayne A. Roeder , Sharath Gopalakrishnamurthy , Alan R. Leewood
IPC分类号： A61F2/82
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2250/0029
摘要： The present embodiments provide a valve for implantation in a patient, for example, an aortic valve. The valve comprises a proximal region comprising a cylindrical shape, and a distal region having a generally rectangular shape comprising opposing flat surfaces that are separated by narrower flat sides. A tapered region is disposed between the proximal and distal regions, where the tapered region comprises two opposing flat surfaces that transition into the opposing flat surfaces of the distal region. The opposing flat surfaces of the tapered region are angled relative to the proximal and distal regions. The opposing flat surfaces at the distal end of the valve allow fluid flow therethrough during antegrade flow and are generally adjacent to one another to inhibit blood flow through the valve during retrograde flow. Optionally, at least one reinforcement member may be coupled to the valve to prevent prolapse of the valve during retrograde flow.
摘要翻译：本实施例提供了一种用于植入患者的阀，例如主动脉瓣。所述阀包括包括圆柱形形状的近侧区域和具有大致矩形形状的远侧区域，所述远侧区域包括由较窄的平坦侧面分开的相对的平坦表面。锥形区域设置在近端区域和远端区域之间，其中锥形区域包括两个相对的平坦表面，其过渡到远端区域的相对的平坦表面。锥形区域的相对的平坦表面相对于近端区域和远端区域成一定角度。在阀的远端处的相对的平坦表面允许流体在顺行流动期间流过其中，并且通常彼此相邻以在逆行流动期间抑制血液通过阀的流动。可选地，至少一个加强构件可以联接到瓣膜，以防止在逆行流动期间瓣膜脱垂。

4. 发明授权

US09180030B2 Low profile non-symmetrical stent 有权
标题翻译：薄型非对称支架
公开(公告)号：US09180030B2
公开(公告)日：2015-11-10
申请号：US12332904
申请日：2008-12-11
申请人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A. M. Chuter , Blayne A. Roeder , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew S. Huser , Jarin Kratzberg , Erik E. Rasmussen , Bent Oehlenschlaeger , Kim Mogelvang Jensen
发明人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A. M. Chuter , Blayne A. Roeder , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew S. Huser , Jarin Kratzberg , Erik E. Rasmussen , Bent Oehlenschlaeger , Kim Mogelvang Jensen
IPC分类号： A61F2/06 , A61F2/86 , A61F2/856 , A61F2/915 , A61F2/07 , A61F2/848
CPC分类号： A61F2/07 , A61F2/852 , A61F2/856 , A61F2/86 , A61F2/89 , A61F2/915 , A61F2002/065 , A61F2002/075 , A61F2002/825 , A61F2002/8486 , A61F2002/91516 , A61F2002/91566 , A61F2220/0016 , A61F2220/0075 , A61F2230/0013
摘要： A stent for use in a medical procedure having opposing sets of curved apices, where the curved section of one set of apices has a radius of curvature that is greater than the curved section of the other set of apices. One or more such stents may be attached to a graft material for use in endovascular treatment of, for example, aneurysm, thoracic dissection, or other body vessel condition.
摘要翻译：一种用于医疗过程的支架，其具有相对的一组曲面顶点，其中一组顶点的弯曲部分的曲率半径大于另一组顶点的弯曲部分。一个或多个这样的支架可以附着到移植物材料上，以用于血管内治疗例如动脉瘤，胸部解剖或其它身体血管状态。

5. 发明申请

US20110118821A1 LOW PROFILE NON-SYMMETRICAL STENT 有权
标题翻译：低剖面非对称性STENT
公开(公告)号：US20110118821A1
公开(公告)日：2011-05-19
申请号：US12904452
申请日：2010-10-14
申请人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A.M. Chuter , Blayne A. Roeder , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew S. Huser
发明人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A.M. Chuter , Blayne A. Roeder , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew S. Huser
IPC分类号： A61F2/82
CPC分类号： A61F2/89 , A61F2/07 , A61F2/848 , A61F2/852 , A61F2/856 , A61F2/915 , A61F2002/061 , A61F2002/065 , A61F2002/075 , A61F2002/826 , A61F2002/8483 , A61F2002/8486 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/91541 , A61F2210/0014 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/006
摘要： Various stents and stent-graft systems for treatment of medical conditions are disclosed. In one embodiment, an exemplary stent-graft system may be used for endovascular treatment of a thoracic aortic aneurysm. The stent-graft system may comprise proximal and distal components, each comprising a graft having proximal and distal ends, where upon deployment the proximal and distal components at least partially overlap with one another to provide a fluid passageway therebetween. The proximal component may comprise a proximal stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where a radius of curvature of at least one of the proximal apices may be greater than the radius of curvature of at least one of the distal apices. The distal component may comprise a proximal z-stent coupled to the graft, where the proximal end of the graft comprises at least scallop formed therein that generally follows the shape of the proximal z-stent. Further, the distal component may comprise at least one z-stent stent coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal component.
摘要翻译：公开了用于治疗医疗条件的各种支架和支架移植系统。在一个实施方案中，示例性支架移植物系统可用于胸主动脉瘤的血管内治疗。支架移植系统可以包括近端和远端部件，每个部件包括具有近端和远端的移植物，其中在展开时，近端和远端部件至少部分地彼此重叠以在其间提供流体通道。近端部件可以包括近端支架，其具有通过多个大致直线部分连接的多个近端和远侧顶点，其中近端顶点中的至少一个的曲率半径可以大于至少一个的近端顶点的曲率半径的远端顶点。远侧部件可以包括联接到移植物的近端Z支架，其中移植物的近端包括至少形成在其中的扇形，其大致遵循近端z支架的形状。此外，远侧部件可以包括联接到移植物的远端并从其远端延伸的至少一个z支架支架，其减少远侧部件的近端迁移。

6. 发明申请

US20100161026A1 LOW PROFILE NON-SYMMETRICAL STENT 有权
标题翻译：低剖面非对称性STENT
公开(公告)号：US20100161026A1
公开(公告)日：2010-06-24
申请号：US12622351
申请日：2009-11-19
申请人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A.M. Chuter , Blayne A. Roeder , Steven J. Charlesbois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew Huser , Jarin Kratzberg , Erik E. Rasmussen , Bent Oehlenschlaeger , Kim Møgelvang Jensen
发明人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A.M. Chuter , Blayne A. Roeder , Steven J. Charlesbois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew Huser , Jarin Kratzberg , Erik E. Rasmussen , Bent Oehlenschlaeger , Kim Møgelvang Jensen
IPC分类号： A61F2/06 , A61F2/82
CPC分类号： A61F2/07 , A61F2/856 , A61F2/86 , A61F2/89 , A61F2/915 , A61F2002/065 , A61F2002/075 , A61F2002/8486 , A61F2002/91516 , A61F2002/91558 , A61F2210/0014 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/0013 , A61F2230/005 , A61F2230/0054 , A61F2230/0067
摘要： A stent for use in a medical procedure having opposing sets of curved apices, where the curved section of one set of apices has a radius of curvature that is greater than the curved section of the other set of apices. One or more such stents may be attached to a graft material for use in endovascular treatment of, for example, aneurysm, thoracic dissection, or other body vessel condition.
摘要翻译：一种用于医疗过程的支架，其具有相对的一组曲面顶点，其中一组顶点的弯曲部分的曲率半径大于另一组顶点的弯曲部分。一个或多个这样的支架可以附着到移植物材料上，以用于血管内治疗例如动脉瘤，胸部解剖或其它身体血管状态。

7. 发明授权

US08740966B2 Low profile non-symmetrical stent 有权
标题翻译：薄型非对称支架
公开(公告)号：US08740966B2
公开(公告)日：2014-06-03
申请号：US12622351
申请日：2009-11-19
申请人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A. M. Chuter , Blayne A. Roeder , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew Huser , Jarin Kratzberg , Erik E. Rasmussen , Bent Oehlenschlaeger , Kim Møgelvang Jensen
发明人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A. M. Chuter , Blayne A. Roeder , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew Huser , Jarin Kratzberg , Erik E. Rasmussen , Bent Oehlenschlaeger , Kim Møgelvang Jensen
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/856 , A61F2/86 , A61F2/89 , A61F2/915 , A61F2002/065 , A61F2002/075 , A61F2002/8486 , A61F2002/91516 , A61F2002/91558 , A61F2210/0014 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/0013 , A61F2230/005 , A61F2230/0054 , A61F2230/0067
摘要： A stent for use in a medical procedure having opposing sets of curved apices, where the curved section of one set of apices has a radius of curvature that is greater than the curved section of the other set of apices. One or more such stents may be attached to a graft material for use in endovascular treatment of, for example, aneurysm, thoracic dissection, or other body vessel condition.
摘要翻译：一种用于医疗过程中的支架，其具有相对的一组弯曲顶点，其中一组顶点的弯曲部分具有比另一组顶点的弯曲部分更大的曲率半径。一个或多个这样的支架可以附着到移植物材料上，以用于血管内治疗例如动脉瘤，胸部解剖或其它身体血管状态。

8. 发明授权

US09226813B2 Low profile non-symmetrical stent 有权
标题翻译：薄型非对称支架
公开(公告)号：US09226813B2
公开(公告)日：2016-01-05
申请号：US12904452
申请日：2010-10-14
申请人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A. M. Chuter , Blayne A. Roeder , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew S. Huser
发明人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A. M. Chuter , Blayne A. Roeder , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew S. Huser
IPC分类号： A61F2/06 , A61F2/07 , A61F2/848 , A61F2/915 , A61F2/852 , A61F2/856 , A61F2/82 , A61F2/89
CPC分类号： A61F2/89 , A61F2/07 , A61F2/848 , A61F2/852 , A61F2/856 , A61F2/915 , A61F2002/061 , A61F2002/065 , A61F2002/075 , A61F2002/826 , A61F2002/8483 , A61F2002/8486 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/91541 , A61F2210/0014 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/006
摘要： Various stents and stent-graft systems for treatment of medical conditions are disclosed. In one embodiment, an exemplary stent-graft system may be used for endovascular treatment of a thoracic aortic aneurysm. The stent-graft system may comprise proximal and distal components, each comprising a graft having proximal and distal ends, where upon deployment the proximal and distal components at least partially overlap with one another to provide a fluid passageway therebetween. The proximal component may comprise a proximal stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where a radius of curvature of at least one of the proximal apices may be greater than the radius of curvature of at least one of the distal apices. The distal component may comprise a proximal z-stent coupled to the graft, where the proximal end of the graft comprises at least scallop formed therein that generally follows the shape of the proximal z-stent. Further, the distal component may comprise at least one z-stent stent coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal component.
摘要翻译：公开了用于治疗医疗条件的各种支架和支架移植系统。在一个实施方案中，示例性支架移植物系统可用于胸主动脉瘤的血管内治疗。支架移植系统可以包括近端和远端部件，每个部件包括具有近端和远端的移植物，其中在展开时，近端和远端部件至少部分地彼此重叠以在其间提供流体通道。近端部件可以包括近端支架，其具有通过多个大致直的部分连接的多个近端和远侧顶点，其中近端顶点中的至少一个的曲率半径可以大于至少一个的近端顶点的曲率半径的远端顶点。远侧部件可以包括联接到移植物的近端Z支架，其中移植物的近端包括至少形成在其中的扇形，其大致遵循近端z支架的形状。此外，远侧部件可以包括联接到移植物的远端并从其远端延伸的至少一个z支架支架，其减少远侧部件的近端迁移。

9. 发明申请

US20090024137A1 Prosthesis Delivery and Deployment Device 有权
标题翻译：假体交付和部署设备
公开(公告)号：US20090024137A1
公开(公告)日：2009-01-22
申请号：US12173277
申请日：2008-07-15
申请人： Timothy A. Chuter , David D. Grewe , Blayne A. Roeder , Alan R. Leewood
发明人： Timothy A. Chuter , David D. Grewe , Blayne A. Roeder , Alan R. Leewood
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9517
摘要： A device for delivering and deploying a prosthesis is described and comprises an elongate sheath having a sheath lumen and a delivery catheter slidably disposed within the sheath lumen. A deployment assist mechanism may be coupled to the delivery catheter and the sheath and configured to apply a retraction force to the delivery catheter and the sheath. Additional devices, systems, and methods of delivering and deploying a prosthesis are described.
摘要翻译：描述了用于递送和展开假体的装置，并且包括具有鞘腔的细长护套和可滑动地设置在鞘腔内的输送导管。部署辅助机构可以联接到输送导管和护套并且被配置为向递送导管和护套施加缩回力。描述了递送和部署假体的附加装置，系统和方法。

10. 发明授权

US09119742B2 Prosthesis delivery and deployment device 有权
标题翻译：假体递送和部署装置
公开(公告)号：US09119742B2
公开(公告)日：2015-09-01
申请号：US12173277
申请日：2008-07-15
申请人： Timothy A. Chuter , David D. Grewe , Blayne A. Roeder , Alan R. Leewood
发明人： Timothy A. Chuter , David D. Grewe , Blayne A. Roeder , Alan R. Leewood
IPC分类号： A61F2/966 , A61F2/95
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9517
摘要： A device for delivering and deploying a prosthesis is described and comprises an elongate sheath having a sheath lumen and a delivery catheter slidably disposed within the sheath lumen. A deployment assist mechanism may be coupled to the delivery catheter and the sheath and configured to apply a retraction force to the delivery catheter and the sheath. Additional devices, systems, and methods of delivering and deploying a prosthesis are described.
摘要翻译：描述了用于递送和展开假体的装置，并且包括具有鞘腔的细长护套和可滑动地设置在鞘腔内的输送导管。部署辅助机构可以联接到输送导管和护套并且被配置为向递送导管和护套施加缩回力。描述了递送和部署假体的附加装置，系统和方法。

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