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1. 发明申请

US20090327229A1 AUTOMATIC KNOWLEDGE-BASED GEOGRAPHICAL ORGANIZATION OF DIGITAL MEDIA 审中-公开
标题翻译：基于自动知识的数字媒体地理组织
公开(公告)号：US20090327229A1
公开(公告)日：2009-12-31
申请号：US12147573
申请日：2008-06-27
申请人： Tim O'Connor , Tomasz Kasperkiewicz
发明人： Tim O'Connor , Tomasz Kasperkiewicz
IPC分类号： G06F7/06 , G06F17/30
CPC分类号： G06F16/58
摘要： Various techniques for a method for generating location information for a digital media file. In one implementation, the method may include receiving a first digital media file with location information and a second digital media file without location information, receiving a location hierarchy of the first digital media file, wherein the location hierarchy is determined using a reverse-geocoding algorithm and using the location hierarchy of the first digital media file to determine a location hierarchy of the second digital media file.
摘要翻译：用于产生数字媒体文件的位置信息的方法的各种技术。在一个实现中，该方法可以包括接收具有位置信息的第一数字媒体文件和没有位置信息的第二数字媒体文件，接收第一数字媒体文件的位置层次结构，其中使用反向地理编码算法以及使用所述第一数字媒体文件的位置层级来确定所述第二数字媒体文件的位置层级。

2. 发明授权

US08221822B2 Medical device coating by laser cladding 失效
标题翻译：医疗器械涂层采用激光熔覆
公开(公告)号：US08221822B2
公开(公告)日：2012-07-17
申请号：US12182703
申请日：2008-07-30
申请人： Aiden Flanagan , Tim O'Connor
发明人： Aiden Flanagan , Tim O'Connor
IPC分类号： A61L33/00 , B05D3/00 , B05D1/36 , B05D1/02 , B29D22/00 , B22D3/00
CPC分类号： A61L31/146 , A61L27/16 , A61L27/54 , A61L27/56 , A61L31/16 , A61L2300/608 , B05D1/12 , B05D3/0466 , B05D3/06 , B05D7/52 , B05D2202/00 , B23K26/32 , B23K26/324 , B23K26/34 , B23K35/0244 , B23K35/365 , B23K2101/34 , B23K2103/30 , B23K2103/50 , B23K2103/52 , B33Y80/00 , Y10T428/12 , Y10T428/1352 , Y10T428/1355
摘要： Methods for making medical devices having porous coatings. Methods may comprise providing a tubing section having inner and outer surfaces and positioning a nozzle proximate to a target surface of the parent tubing section. A powder form of the porous coating may be delivered toward the tubing section, and a laser may be directed at the powder to melt the powder to form a melt pool. The melt pool can solidify to form the porous coating on the target surface. Portions of the parent tubing section may then be cut away to form the support structure of the medical device, such as a stent.
摘要翻译：制造具有多孔涂层的医疗装置的方法。方法可以包括提供具有内表面和外表面并且将喷嘴定位在母管部分的目标表面附近的管段。多孔涂层的粉末形式可以朝向管道部分递送，并且激光可以被引导到粉末以熔化粉末以形成熔池。熔池可以固化以在目标表面上形成多孔涂层。然后可以将母管部分的部分切除以形成医疗装置（例如支架）的支撑结构。

3. 发明授权

US07901726B2 Porous medical articles for therapeutic agent delivery 失效
标题翻译：用于治疗剂递送的多孔医疗用品
公开(公告)号：US07901726B2
公开(公告)日：2011-03-08
申请号：US11897808
申请日：2007-08-31
申请人： David McMorrow , Anthony Malone , Tim O'Connor , Barry J. O'Brien
发明人： David McMorrow , Anthony Malone , Tim O'Connor , Barry J. O'Brien
IPC分类号： B05D3/00
CPC分类号： A61L31/14 , A61L31/146 , A61L31/16 , A61L2300/416
摘要： According to an aspect of the present invention a method is provided which a porous medical article is contacted with a solution that contains a therapeutic agent and a solvent in order to load the pores of the medical article, after which the solvent is sublimated.
摘要翻译：根据本发明的一个方面，提供了一种方法，使多孔医疗制品与含有治疗剂和溶剂的溶液接触，以便加载医疗用品的孔，之后溶剂升华。

4. 发明授权

US07875069B2 Stent with support element 失效
标题翻译：支架与支撑元件
公开(公告)号：US07875069B2
公开(公告)日：2011-01-25
申请号：US11526278
申请日：2006-09-21
申请人： Barry Heaney , Dave McMorrow , Anthony Malone , Aiden Flanagan , Tim O'Connor
发明人： Barry Heaney , Dave McMorrow , Anthony Malone , Aiden Flanagan , Tim O'Connor
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/852 , A61F2/86 , A61F2220/0033 , A61F2220/005 , A61F2220/0058 , A61F2250/0063 , A61F2250/0068
摘要： An implantable stent comprising a first strut having an abluminal surface, and subluminal surface, and at least one side surface; a first depression formed in the abluminal surface; and a first support element at least partially disposed in the first depression; wherein at least a portion of the first support element extends beyond the abluminal surface of the first strut.
摘要翻译：一种可植入支架，其包括具有近端表面的第一支柱和亚锥形表面以及至少一个侧表面; 形成在外侧表面的第一凹陷; 以及至少部分地设置在所述第一凹部中的第一支撑元件; 其中所述第一支撑元件的至少一部分延伸超过所述第一支柱的所述外侧表面。

5. 发明申请

US20090081272A1 MEDICAL DEVICES HAVING A METAL PARTICULATE COMPOSITION FOR CONTROLLED DIFFUSION 审中-公开
标题翻译：具有用于控制扩散的金属颗粒组合物的医疗装置
公开(公告)号：US20090081272A1
公开(公告)日：2009-03-26
申请号：US11860233
申请日：2007-09-24
申请人： John Clarke , David McMorrow , Aiden Flanagan , Tim O'Connor , Jan Weber , Barry J. O'Brien
发明人： John Clarke , David McMorrow , Aiden Flanagan , Tim O'Connor , Jan Weber , Barry J. O'Brien
IPC分类号： A61F2/00
CPC分类号： A61L31/022 , A61L31/14 , A61L31/16 , A61L2300/00
摘要： An implantable or insertable medical device is provided which includes as components: (a) a substrate component comprising a depression that is at least partially filled with a therapeutic agent-containing material that comprises a first therapeutic agent, and (b) a particulate composition disposed in the depression such that it regulates transport of chemical species between the depression and the exterior of the device upon implantation or insertion of the device into a subject.
摘要翻译：提供了一种植入式或可插入的医疗装置，其包括作为部件：（a）底物组分，其包含至少部分地填充有包含第一治疗剂的含治疗剂的材料的凹陷，和（b）处理的颗粒组合物在凹陷中，使得在将装置植入或插入到受试者中时，其调节化学物质在装置的凹陷和外部之间的运输。

6. 发明申请

US20080243231A1 Medical device with a porous surface for delivery of a therapeutic agent 有权
标题翻译：具有用于递送治疗剂的多孔表面的医疗装置
公开(公告)号：US20080243231A1
公开(公告)日：2008-10-02
申请号：US12072666
申请日：2008-02-27
申请人： Aiden Flanagan , David McMorrow , Anthony Malone , Tim O'Connor
发明人： Aiden Flanagan , David McMorrow , Anthony Malone , Tim O'Connor
IPC分类号： B05D3/12 , A61F2/06
CPC分类号： A61F2/06 , A61L31/082 , A61L31/146 , A61L31/16 , A61L2300/416
摘要： The present invention is generally directed to implantable medical devices for delivering therapeutic agents to the body tissue of a patient and methods for making such medical devices. In particular, the present invention is directed to implantable medical devices, such as intravascular stents, having a surface that includes a plurality of cavities and a plurality of pores and a composition disposed in the pores and/or cavities, as well as, implantable medical devices, such as intravascular stents, having a surface that has a coating composition disposed on the surface, wherein the coating composition includes a plurality of cavities and a plurality of pores and another coating composition disposed in the pores and/or cavities.
摘要翻译：本发明一般涉及用于将治疗剂递送到患者的身体组织的可植入医疗装置和用于制造这种医疗装置的方法。特别地，本发明涉及可植入医疗装置，例如血管内支架，其具有包括多个空腔的表面和多个孔以及设置在孔和/或空腔中的组合物，以及植入式医疗装置，例如血管内支架，其具有设置在表面上的涂层组合物的表面，其中所述涂层组合物包括多个空腔和多个孔以及设置在孔和/或空腔中的另一涂层组合物。

7. 发明申请

US20080241351A1 USING MAGNETISM TO PREPARE A MEDICAL DEVICE 失效
标题翻译：使用MAGNETISM制定医疗器械
公开(公告)号：US20080241351A1
公开(公告)日：2008-10-02
申请号：US12057135
申请日：2008-03-27
申请人： Liliana Atanasoka , Aiden Flanagan , Tim O'Connor , Dave McMorrow , Robert Nolan , Anthony Malone , Jan Weber
发明人： Liliana Atanasoka , Aiden Flanagan , Tim O'Connor , Dave McMorrow , Robert Nolan , Anthony Malone , Jan Weber
IPC分类号： A61L31/16 , B01J19/08 , B05D1/12
CPC分类号： B05B5/00 , A61F2/91 , A61F2210/009 , A61L31/14 , A61L31/146 , A61L31/16 , A61L2300/60 , A61L2300/62 , B05C3/09 , B05D1/18 , B05D1/32 , B05D3/207 , B05D2401/32
摘要： The present invention is directed to methods, processes, and systems for delivering therapeutic agent to a medical device. Under some methods, processes, and systems of the invention, particles including a magnetic material and a therapeutic agent may be directed towards a medical device via magnetic attraction. In another embodiment particles including a magnetic material may force a therapeutic agent/solvent solution into porous matrix by using a magnetic attraction. In still another embodiment, a medical device having at least a portion thereof including a magnetic material is used to attract and adhere particles comprising magnetic material and therapeutic agent to a target surface of the medical device, wherein the particles are fused to the target surface.
摘要翻译：本发明涉及将治疗剂递送到医疗装置的方法，过程和系统。在一些方法下，本发明的方法和系统，包括磁性材料和治疗剂的颗粒可以通过磁吸引而引向医疗装置。在另一个实施方案中，包括磁性材料的颗粒可以通过使用磁吸引剂将治疗剂/溶剂溶液强制成多孔基质。在另一个实施例中，使用包括磁性材料的至少其一部分的医疗装置将包含磁性材料和治疗剂的颗粒吸附并附着到医疗装置的靶表面上，其中所述颗粒与目标表面融合。

8. 发明申请

US20080095921A1 FILM COATING MEDICAL DEVICES 有权
标题翻译：电影涂装医疗器械
公开(公告)号：US20080095921A1
公开(公告)日：2008-04-24
申请号：US11858347
申请日：2007-09-20
申请人： Tim O'Connor , Dave McMorrow , Gabriel Sobrino , Liam Ward , Noel Hynes
发明人： Tim O'Connor , Dave McMorrow , Gabriel Sobrino , Liam Ward , Noel Hynes
IPC分类号： B05D1/22
CPC分类号： B05C1/022 , A61L2420/02
摘要： The present invention relates to a coating assembly and methods that employ the coating assembly to control the thickness of therapeutic or other coatings delivered to a medical device during a coating process. In one embodiment the coating assembly may include a coating plate having a coating transfer surface and a shoulder having a first height, a mandrel moveable over the coating transfer surface, and a coating dispenser positioned in fluid communication with the coating transfer surface. The invention also includes a method of coating a medical device. This method may include placing a medical device on a mandrel, dispensing coating onto a coating transfer surface of a coating plate, moving the mandrel and the medical device over the coating transfer surface of the coating plate so that coating resident on the coating transfer surface transfers to an exposed surface of the medical device, and removing the medical device from the mandrel.
摘要翻译：本发明涉及涂覆组件和方法，其使用涂层组件来控制在涂覆过程期间递送到医疗装置的治疗剂或其它涂层的厚度。在一个实施方案中，涂层组件可以包括具有涂层转移表面和具有第一高度的肩部，可在涂层转移表面上移动的芯棒的涂布板和与涂层转移表面流体连通的涂布分配器。本发明还包括涂覆医疗装置的方法。该方法可以包括将医疗装置放置在心轴上，将涂层分配到涂布板的涂层转移表面上，将心轴和医疗装置移动到涂布板的涂层转移表面上，使得驻留在涂层转移表面上的涂层转移到医疗装置的暴露表面，并且从心轴移除医疗装置。

9. 发明申请

US20080077218A1 INJECTION OF THERAPEUTIC INTO POROUS REGIONS OF A MEDICAL DEVICE 审中-公开
标题翻译：将治疗注射到医疗器械的多孔区域
公开(公告)号：US20080077218A1
公开(公告)日：2008-03-27
申请号：US11856994
申请日：2007-09-18
申请人： Dave McMorrow , Tim O'Connor , Aiden Flanagan , Anthony Malone
发明人： Dave McMorrow , Tim O'Connor , Aiden Flanagan , Anthony Malone
IPC分类号： A61N1/00 , A61F2/06
CPC分类号： A61L31/146 , A61F2/91 , A61F2250/0068 , A61L31/10 , A61L31/16 , A61L2300/00
摘要： The present invention is directed to methods, processes, and systems for selectively driving therapeutic into at least a portion of a porous matrix of a medical implant. Under methods and processes of the invention, a medical implant may be provided having at least a portion thereof comprising a porous matrix. An injector in fluid communication with a fluid source deliver therapeutic within the porous matrix. The porous matrix may be configured to control the elution rate.
摘要翻译：本发明涉及用于选择性地将治疗剂驱动到医用植入物的多孔基质的至少一部分中的方法，方法和系统。在本发明的方法和方法下，可以提供医疗植入物，其至少一部分包括多孔基质。与流体源流体连通的注射器在多孔基质内递送治疗剂。多孔基质可以被配置为控制洗脱速率。

10. 发明申请

US20130066257A1 Design of Interventional Cutting Balloon with Enhanced API Delivery Capability 审中-公开
标题翻译：具有增强的API传送能力的介入切割气球的设计
公开(公告)号：US20130066257A1
公开(公告)日：2013-03-14
申请号：US13608237
申请日：2012-09-10
申请人： Martyn Folan , John Clarke , Aiden Flanagan , Anthony Malone , Tim O'Connor
发明人： Martyn Folan , John Clarke , Aiden Flanagan , Anthony Malone , Tim O'Connor
IPC分类号： A61B17/22 , A61M37/00
CPC分类号： A61M25/104 , A61B17/320725 , A61B2017/22061 , A61M25/1002 , A61M2025/1004 , A61M2025/105 , A61M2025/1059 , A61M2025/1086
摘要： A medical balloon assembly including an inflatable balloon and at least one cutting element extending from the balloon is disclosed. The inflatable balloon includes an outer wall facing outward and an inner wall facing outward. The cutting element comprises a plurality of openings therein including a first opening and a second opening. The first opening is closed off by a portion of the outer wall. The cutting element further includes a passageway extending from the first opening to the second opening. The passageway is defined by the cutting element and the portion of the outer wall which closes off the passageway. The passageway may contain a therapeutic agent.
摘要翻译：公开了一种医用气囊组件，其包括可充气球囊和从球囊延伸的至少一个切割元件。充气气囊包括面向外的外壁和面向外的内壁。切割元件包括多个开口，其中包括第一开口和第二开口。第一开口被外壁的一部分封闭。切割元件还包括从第一开口延伸到第二开口的通道。通道由切割元件和封闭通道的外壁部分限定。通道可以含有治疗剂。

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