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1. 发明申请

US20110041215A1 Lipid Metabolism Protein And Uses Thereof I (BZIP Transcription Factor) 审中-公开
标题翻译：脂质代谢蛋白及其用途I（BZIP转录因子）
公开(公告)号：US20110041215A1
公开(公告)日：2011-02-17
申请号：US12808225
申请日：2008-12-17
申请人： Thorsten Zank , Heiko A. Härtel , Volker Mittendorf
发明人： Thorsten Zank , Heiko A. Härtel , Volker Mittendorf
IPC分类号： A01H1/00 , C07H21/00 , C12N15/63 , C12N5/10 , C12P21/02 , C07K14/415 , A01H5/00 , C12P7/64
CPC分类号： C07K14/415 , C12N15/8245 , C12N15/8247
摘要： The present invention relates to a bZip transcription factor encoding polynucleotides and polypeptides. Further, the present invention relates to the use of the aforementioned nucleic acid sequences and proteins in transgenic plants. In particular, the invention is directed to methods for manipulating sugar-related compounds and for increasing oil level and altering the fatty acid composition in plants and seeds. The invention further relates to methods of using these novel plant polypeptides to stimulate plant growth and/or to increase yield and/or composition of seed storage compounds.
摘要翻译：本发明涉及编码多核苷酸和多肽的bZip转录因子。此外，本发明涉及上述核酸序列和蛋白质在转基因植物中的用途。特别地，本发明涉及用于操纵糖相关化合物和增加油含量和改变植物和种子中的脂肪酸组成的方法。本发明还涉及使用这些新型植物多肽刺激植物生长和/或增加种子储存化合物的产量和/或组成的方法。

2. 发明申请

US20100287665A1 Lipid Metabolism Protein and Uses Thereof III (Pyruvate-Orthophosphate-Dikinase) 审中-公开
标题翻译：脂质代谢蛋白及其用途III（丙酮酸 - 正磷酸 - 定丝激酶）
公开(公告)号：US20100287665A1
公开(公告)日：2010-11-11
申请号：US12808230
申请日：2008-12-17
申请人： Thorsten Zank , Heiko A. Härtel
发明人： Thorsten Zank , Heiko A. Härtel
IPC分类号： A01H1/00 , C12P7/64 , C12N9/12 , C12N5/10 , C12N15/63 , C07H21/04 , C11B1/00 , A01K67/00
CPC分类号： C12N15/8247 , C12N9/1294
摘要： The present invention relates to pyruvate-orthophosphate dikinase encoding polynucleotides and polypeptides. Further, the present invention relates to the use of the aforementioned nucleic acid sequences and proteins in transgenic plants. In particular, the invention is directed to methods for manipulating sugar-related compounds and for increasing oil level and altering the fatty acid composition in plants and seeds. The invention further relates to methods of using these novel plant polypeptides to stimulate plant growth and/or to increase yield and/or composition of seed storage compounds.
摘要翻译：本发明涉及丙酮酸 - 正磷酸二激酶编码多核苷酸和多肽。此外，本发明涉及上述核酸序列和蛋白质在转基因植物中的用途。特别地，本发明涉及用于操纵糖相关化合物和增加油含量和改变植物和种子中的脂肪酸组成的方法。本发明还涉及使用这些新型植物多肽刺激植物生长和/或增加种子储存化合物的产量和/或组成的方法。

3. 发明申请

US20110035841A1 Lipid Metabolism Proteins, Combinations of Lipid Metabolism Proteins and Uses Thereof 审中-公开
标题翻译：脂质代谢蛋白，脂质代谢蛋白的组合及其用途
公开(公告)号：US20110035841A1
公开(公告)日：2011-02-10
申请号：US12808703
申请日：2008-12-10
申请人： Gunnar Plesch , Piotr Puzio , Astrid Blau , Michael Manfred Herold , Birgit Wendel , Beate Kamlage , Florian Schauwecker , Thorsten Zank , Oliver Oswald , Tom Wetjen
发明人： Gunnar Plesch , Piotr Puzio , Astrid Blau , Michael Manfred Herold , Birgit Wendel , Beate Kamlage , Florian Schauwecker , Thorsten Zank , Oliver Oswald , Tom Wetjen
IPC分类号： C12N15/82 , C07H21/02 , C07H21/04 , C12N15/63 , C12N5/10 , C12P21/02 , C07K14/25 , C07K14/245 , C07K16/12 , A01H5/00
CPC分类号： C12N15/8247 , C12N15/8242 , C12N15/8261 , Y02A40/146
摘要： Described herein are inventions in the field of genetic engineering of plants, including combinations of polynucleotides encoding LMPs to improve agronomic, horticultural, and quality traits. This invention also relates to the combination of polynucleotides encoding proteins that are related to the presence of seed storage compounds in plants. More specifically, the present invention relates to LMP polynucleotides encoding lipid metabolism proteins (LMP) and the use of these combinations of these sequences, their order and direction in the combination, and the regulatory elements used to control expression and transcript termination in these combinations in transgenic plants. In particular, the invention is directed to methods for manipulating fatty acid-related compounds and for increasing oil and starch levels and altering the fatty acid composition in plants and seeds. The invention further relates to methods of using these novel combinations of polypeptides to stimulate plant growth, and/or root growth and/or to increase yield and/or composition of seed storage compounds.
摘要翻译：本文描述了植物遗传工程领域的发明，包括编码LMP的多核苷酸的组合，以改善农艺学，园艺学和品质性状。本发明还涉及编码与种子储存化合物在植物中的存在有关的蛋白质的多核苷酸的组合。更具体地，本发明涉及编码脂质代谢蛋白（LMP）的LMP多核苷酸以及这些序列的这些组合的用途，它们在组合中的顺序和方向，以及用于控制这些组合中的表达和转录终止的调控元件转基因植物。特别地，本发明涉及用于操作脂肪酸相关化合物和增加油和淀粉水平并改变植物和种子中的脂肪酸组成的方法。本发明还涉及使用多肽的这些新型组合来刺激植物生长和/或根生长和/或增加种子储存化合物的产量和/或组成的方法。

4. 发明申请

US20090217417A1 Combination of lipid metabolism proteins and uses thereof 审中-公开
标题翻译：脂代谢蛋白的组合及其用途
公开(公告)号：US20090217417A1
公开(公告)日：2009-08-27
申请号：US11989249
申请日：2006-07-14
申请人： Thorsten Zank , Oliver Oswald
发明人： Thorsten Zank , Oliver Oswald
IPC分类号： A01H1/00 , C07H21/00 , C07K2/00 , C12N15/63 , A01H5/00 , A01H5/10
CPC分类号： C12N15/8247 , C07K14/415
摘要： Described herein are inventions in the field of genetic engineering of plants, including combinations of nucleic acid molecules encoding LMPs to improve agronomic, horticultural, and quality traits. This invention relates generally to the combination of nucleic acid sequences encoding proteins that are related to the presence of seed storage compounds in plants. More specifically, the present invention relates to LMP nucleic acid sequences encoding lipid metabolism proteins (LMP) and the use of these combinations of these sequences, their order and direction in the combination, and the regulatory elements used to control expression and transcript termination in these combinations in transgenic plants. In particular, the invention is directed to methods for manipulating fatty acid-related compounds and for increasing oil level and altering the fatty acid composition in plants and seeds. The invention further relates to methods of using these novel combinations of polypeptides to stimulate plant growth and/or to increase yield and/or composition of seed storage compounds.
摘要翻译：本文描述了植物遗传工程领域的发明，包括编码LMP的核酸分子的组合，以改善农艺，园艺和品质性状。本发明一般涉及编码与植物中种子储存化合物的存在有关的蛋白质的核酸序列的组合。更具体地，本发明涉及编码脂质代谢蛋白（LMP）的LMP核酸序列以及这些序列的这些组合的用途，它们在组合中的顺序和方向，以及用于控制这些序列中的表达和转录终止的调控元件转基因植物中的组合。特别地，本发明涉及用于操作脂肪酸相关化合物和增加油含量和改变植物和种子中的脂肪酸组成的方法。本发明还涉及使用这些多肽的这些新型组合来刺激植物生长和/或增加种子储存化合物的产量和/或组成的方法。

5. 发明授权

US07537920B2 Method for the production of polyunsaturated fatty acids 有权
标题翻译：生产多不饱和脂肪酸的方法
公开(公告)号：US07537920B2
公开(公告)日：2009-05-26
申请号：US10547447
申请日：2004-01-29
申请人： Andreas Renz , Ernst Heinz , Amine Abbadi , Frederic Domergue , Thorsten Zank
发明人： Andreas Renz , Ernst Heinz , Amine Abbadi , Frederic Domergue , Thorsten Zank
IPC分类号： C12N9/12 , C12N1/20 , C12N15/00 , C07H21/04
CPC分类号： C12N15/8247 , C12N9/1029 , C12P7/6427 , C12P7/6472
摘要： The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-CoA:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.
摘要翻译：本发明涉及通过将核酸引入生物体中来生产多不饱和脂肪酸的方法，该生物体编码具有酰基-CoA：溶血磷脂一羧酰基转移酶活性的多肽。有利地，如果合适的话，这些核酸序列可以与编码脂肪酸或脂质代谢的生物合成多肽的其它核酸序列一起在转基因生物中表达。本发明还涉及核酸序列，包含本发明的核酸序列的核酸构建体，包含核酸序列和/或核酸构建体的载体以及包含上述核酸序列的转基因生物，核酸构建体和/或载体。本发明的另一部分涉及通过本发明的方法生产的油，脂和/或脂肪酸及其用途。

6. 发明申请

US20090083882A1 METHOD FOR INCREASING THE TOTAL OIL CONTENT IN OIL PLANTS 审中-公开
标题翻译：增加油田总油含量的方法
公开(公告)号：US20090083882A1
公开(公告)日：2009-03-26
申请号：US12092603
申请日：2006-11-06
申请人： Thorsten Zank , Oliver Oswald , Jorg Bauer , Helene Vigeolas , Peter Geigenberger , Peter Waldeck , Mark Stitt
发明人： Thorsten Zank , Oliver Oswald , Jorg Bauer , Helene Vigeolas , Peter Geigenberger , Peter Waldeck , Mark Stitt
IPC分类号： C12N15/82 , A01H1/04
CPC分类号： C12N15/8247 , C12N9/0006
摘要： The invention relates to methods of increasing the total oil content and/or the glycerol 3-phosphate content in transgenic oil crop plants which comprise at least 20% by weight of oleic acid based on the total fatty acid content, preferably in plant seeds, by expressing glycerol 3-phosphate dehydrogenases (G3PDHs) from yeasts, preferably from Saccharomyces cerevisiae. The oil and/or the free fatty acids obtained in the process are advantageously added to polymers, foodstuffs, feedstuffs, cosmetics, pharmaceuticals or products with industrial applications.
摘要翻译：本发明涉及增加转基因油料作物植物中总油含量和/或甘油3-磷酸盐含量的方法，其中基于总脂肪酸含量，优选在植物种子中，包含至少20重量％的油酸，通过从酵母，优选来自酿酒酵母（Saccharomyces cerevisiae）表达甘油3-磷酸脱氢酶（G3PDH）。在该方法中获得的油和/或游离脂肪酸有利地加入到具有工业应用的聚合物，食品，饲料，化妆品，药物或产品中。

7. 发明申请

US20080120748A1 Nucleic Acid Molecules Encoding Kcs-Like Polypeptides And Methods Of Use 审中-公开
标题翻译：编码Kcs样多肽的核酸分子及其使用方法
公开(公告)号：US20080120748A1
公开(公告)日：2008-05-22
申请号：US11793630
申请日：2005-12-20
申请人： Thorsten Zank , Oliver Oswald
发明人： Thorsten Zank , Oliver Oswald
IPC分类号： C12N15/82 , C12N9/00 , C12N15/11 , A01H5/00 , C12N15/00
CPC分类号： C12N9/1029 , C12N15/8247
摘要： This invention relates generally to nucleic acid sequences encoding proteins that are related to the presence of seed storage compounds in plants. More specifically, the present invention relates to KCS-like nucleic acid sequences encoding lipid metabolism proteins (LMP) and the use of these sequences in transgenic plants. In particular, the invention is directed to methods for manipulating fatty acid-related compounds and for increasing oil level and altering the fatty acid composition in plants and seeds. The invention further relates to methods of using these novel plant polypeptides to stimulate plant growth and/or to increase yield and/or composition of seed storage compounds.
摘要翻译：本发明一般涉及编码与种子储存化合物在植物中的存在有关的蛋白质的核酸序列。更具体地，本发明涉及编码脂质代谢蛋白（LMP）的KCS样核酸序列和这些序列在转基因植物中的用途。特别地，本发明涉及用于操作脂肪酸相关化合物和增加油含量和改变植物和种子中的脂肪酸组成的方法。本发明还涉及使用这些新型植物多肽刺激植物生长和/或增加种子储存化合物的产量和/或组成的方法。

8. 发明授权

US09090902B2 Nucleic acids encoding desaturases and modified plant oil 有权
标题翻译：编码去饱和酶和改性植物油的核酸
公开(公告)号：US09090902B2
公开(公告)日：2015-07-28
申请号：US13060458
申请日：2009-08-25
申请人： Jörg Bauer , Toralf Senger , Thorsten Zank , Xiao Qiu , Guohai Wu
发明人： Jörg Bauer , Toralf Senger , Thorsten Zank , Xiao Qiu , Guohai Wu
IPC分类号： C12N15/82 , C12N5/14 , C12N9/02 , C12N9/00
CPC分类号： C12N15/8247 , C12N5/14 , C12N9/00 , C12N9/0004
摘要： The present invention relates to nucleic acids derived from Drechslera tritici-repentis, Cylindorcarpon herteronema, Diploida natalensis, Stagonospora nodorum, Microdochium nivalae and Periplaneta americana. The invention also relates to the individual coding sequences and to proteins encoded by these sequences in combination with other sequences as well as to a process for converting oleic acid to linoleic acid to Iinoleic acid and the production of arachidonic acid, eicosapentaenoic acid and/or docosahexaenoic acid in a plant.
摘要翻译：本发明涉及来自Drechslera tritici-repentis，Cylindorcarpon herteronema，Diploida natalensis，Stagonospora nodorum，Microdochium nivalae和Periplaneta americana的核酸。本发明还涉及个体编码序列和由这些序列与其它序列组合编码的蛋白质以及将油酸转化为亚油酸至亚油酸的方法，以及花生四烯酸，二十碳五烯酸和/或二十二碳六烯酸的生产酸在植物中。

9. 发明授权

US08486671B2 Method for the production of polyunsaturated fatty acids 有权
公开(公告)号：US08486671B2
公开(公告)日：2013-07-16
申请号：US12417171
申请日：2009-04-02
申请人： Andreas Renz , Ernst Heinz , Amine Abbadi , Frederic Domergue , Thorsten Zank
发明人： Andreas Renz , Ernst Heinz , Amine Abbadi , Frederic Domergue , Thorsten Zank
IPC分类号： C12P7/64 , C12N9/12
CPC分类号： C12N15/8247 , C12N9/1029 , C12P7/6427 , C12P7/6472
摘要： The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-CoA:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.

10. 发明授权

US08344205B2 Plants with increased yield 失效
标题翻译：植物增产
公开(公告)号：US08344205B2
公开(公告)日：2013-01-01
申请号：US12444728
申请日：2007-10-12
申请人： Thorsten Zank , Oliver Oswald , Jörg Bauer , Rita Maria Zrenner , Silke Koslowsky
发明人： Thorsten Zank , Oliver Oswald , Jörg Bauer , Rita Maria Zrenner , Silke Koslowsky
IPC分类号： A01H1/00 , A01H5/00 , C12N15/00
CPC分类号： C12N15/8247 , C12N9/1235 , C12N15/8261 , Y02A40/146
摘要： This invention relates generally to plant cells and/or plants with increased yield as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of polypeptides associated with the intermediate phosphoribosylpyrophosphate (PRPP) in plants. In particular, this invention relates to plant cells and/or plants with increased yield as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of phosphoribosyl pyrophosphate synthases (PRPP synthetase, PRS) The invention also deals with methods of producing and screening for and breeding such plant cells and/or plants.
摘要翻译：与相应的未转化的野生型植物细胞相比，通过增加或产生与植物中的中间磷酸核糖基焦磷酸（PRPP）相关的多肽的一种或多种活性，本发明一般涉及具有增加的产量的植物细胞和/或植物。特别地，本发明涉及通过增加或产生磷酸核糖焦磷酸合酶（PRPP合成酶，PRS）的一种或多种活性而与相应的未转化的野生型植物细胞相比具有增加的产量的植物细胞和/或植物。本发明还涉及使用生产和筛选和繁殖这种植物细胞和/或植物的方法。

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