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1. 发明申请

US20070141105A1 Engineered Biological Matrices 审中-公开
标题翻译：工程生物矩阵
公开(公告)号：US20070141105A1
公开(公告)日：2007-06-21
申请号：US11539580
申请日：2006-10-06
申请人： Thomas Stein , Mark Powers , Jonathan Cooper , Sorin Damian , Pieter Johannes Huiberts , Kenneth Guiseley
发明人： Thomas Stein , Mark Powers , Jonathan Cooper , Sorin Damian , Pieter Johannes Huiberts , Kenneth Guiseley
IPC分类号： A61F2/02 , A61K9/14 , C12N5/02
CPC分类号： A61L27/52 , A61K47/6903 , A61L27/50 , A61L27/54 , A61L2300/604 , C12N5/0068 , C12N2533/76
摘要： Biocompatible matrices or implants on which one or more specific cell-interactive molecules (“biomolecules”) can be immobilized have been developed. The matrices allow for the independent control of ligand concentration and matrix strength. In one embodiment, the matrix or implant is modified with one or more moieties capable of complexing bioconjugates prepared from one or more biomolecules. Suitable moieties include phenyl boronic acid complexing agents, such as salicylhydroxamic acid, which can complex to one or more biomolecules containing one or more phenyl boronic acid moieties. The biomolecules may be anchored to the matrix via a spacer molecule, which may allow for greater mobility of the biomolecules in aqueous solution. In one embodiment, the matrix is a hydrogel material which has been doubly-derivatized, wherein ligand concentration and matrix strength can be independently controlled. The matrices and implants can be used in vivo and in vitro applications including diagnostics, biosensors, bioprocess engineering, tissue engineering, regeneration and repair, and drug delivery.
摘要翻译：已经开发了可以固定有一个或多个特定细胞相互作用分子（“生物分子”）的生物相容性基质或植入物。基质允许独立控制配体浓度和基质强度。在一个实施方案中，基质或植入物用能够络合由一种或多种生物分子制备的生物缀合物的一个或多个部分修饰。合适的部分包括苯基硼酸络合剂，例如水杨酸异羟肟酸，其可与含有一个或多个苯基硼酸部分的一种或多种生物分子络合。生物分子可以通过间隔分子锚定到基质，这可以允许生物分子在水溶液中更大的迁移率。在一个实施方案中，基质是双重衍生的水凝胶材料，其中配体浓度和基质强度可以独立控制。基质和植入物可用于体内和体外应用，包括诊断，生物传感器，生物过程工程，组织工程，再生和修复以及药物递送。

2. 发明申请

US20100299020A1 SYSTEM AND METHOD FOR PROVISIONING A VEHICLE INTERFACE MODULE 有权
标题翻译：用于提供车辆接口模块的系统和方法
公开(公告)号：US20100299020A1
公开(公告)日：2010-11-25
申请号：US12852047
申请日：2010-08-06
申请人： Gerhard Koepf , Robert Yandrofski , Roy G. Perry , Jonathan Cooper
发明人： Gerhard Koepf , Robert Yandrofski , Roy G. Perry , Jonathan Cooper
IPC分类号： G06F19/00
CPC分类号： G06F11/25 , G06F11/273 , G07C5/008
摘要： The present invention provides systems and methods for provisioning a vehicle interface module comprising receiving a VIM from a VIM manufacturer and entering appropriate VIM data into a dealer inventory, activating a SIM card for the VIM and installing the VIM in a predetermined vehicle, selecting a wireless activated VIM from the dealer inventory and connecting the VIM to an OBD-II port of the vehicle, connecting a configuration PC to the VIM and downloading a modem configuration, selecting and downloading a vehicle-specific configuration file, accessing a telematics services provider's web portal, entering appropriate vehicle data, and associating the vehicle with the VIM, installing the VIM in the predetermined vehicle, and conducting an installation verification test.
摘要翻译：本发明提供用于提供车辆接口模块的系统和方法，包括从VIM制造商接收VIM并将合适的VIM数据输入经销商库存，激活用于VIM的SIM卡并将VIM安装在预定车辆中，选择无线从经销商库存中激活VIM，并将VIM连接到车辆的OBD-II端口，将配置PC连接到VIM并下载调制解调器配置，选择和下载特定于车辆的配置文件，访问远程信息处理服务提供商的门户网站，输入适当的车辆数据，并将车辆与VIM相关联，将VIM安装在预定车辆中，并进行安装验证测试。

3. 发明申请

US20060019399A1 Devices and methods for correlated analysis of multiple protein or peptide samples 审中-公开
标题翻译：多种蛋白质或肽样品相关分析的装置和方法
公开(公告)号：US20060019399A1
公开(公告)日：2006-01-26
申请号：US11171427
申请日：2005-07-01
申请人： Brian Balgley , Jonathan Cooper , Cheng Lee , Donald DeVoe
发明人： Brian Balgley , Jonathan Cooper , Cheng Lee , Donald DeVoe
IPC分类号： G01N33/00
CPC分类号： C07K1/16 , G01N30/466 , G01N35/1095 , G01N2030/8813 , H01J49/009 , H01J49/0431
摘要： Disclosed is a system for performing multiple analyses of protein and/or peptide samples and correlating the results of the analyses. The system comprises a sample inlet, a splitter means, at least two sample delivery capillaries, at least two sample deposition tools, and at least two sample collectors, wherein said splitter means is in fluid communication with the sample inlet and the sample delivery capillaries, and wherein liquid flow entering the splitter means is split into a number of sub-flows equal to the number of sample delivery capillaries. In one preferred embodiment, at least one microenzyme reactor is interfaced to a first sample delivery capillary in order to digest a protein sample within the capillary, while a second sample delivery capillary does not contain a microenzyme reactor, thereby enabling correlated analysis of the same protein sample in digested and undigested form. Methods for performing two or more analyses of protein and/or peptide samples and correlating the results of the analyses are also disclosed.
摘要翻译：公开了一种用于进行蛋白质和/或肽样品的多次分析并将分析结果相关联的系统。该系统包括样品入口，分离装置，至少两个样品输送毛细管，至少两个样品沉积工具和至少两个样品收集器，其中所述分离装置与样品入口和样品输送毛细管流体连通，并且其中进入分离装置的液体流被分成等于样品递送毛细管数量的多个子流。在一个优选的实施方案中，至少一个微酶反应器与第一样品递送毛细管连接，以便消化毛细管内的蛋白质样品，而第二样品递送毛细管不含有微酶反应器，从而能够进行相同蛋白质的相关分析采样消化和未消化形式。还公开了对蛋白质和/或肽样品进行两次或多次分析并关联分析结果的方法。

4. 发明申请

US20100044582A1 Sanitizer for portable electronic devices 失效
标题翻译：消毒剂用于便携式电子设备
公开(公告)号：US20100044582A1
公开(公告)日：2010-02-25
申请号：US12460356
申请日：2009-07-16
申请人： Jonathan Cooper , Robert E. Cannuscio
发明人： Jonathan Cooper , Robert E. Cannuscio
IPC分类号： G01N23/00
CPC分类号： A61L2/10 , A61L2/24 , A61L2202/122 , A61L2202/14 , A61L2202/16
摘要： A sanitizer for sanitizing a portable electronic device is provided, the sanitizer having a base including a cavity for receiving the electronic device, at least one ultraviolet radiation source for emitting ultraviolet radiation into the cavity, a cover cooperating with the base, the cover moving between an open position wherein the electronic device can be inserted into or removed from the cavity and a closed position wherein the cavity is enclosed so as to substantially maintain the ultraviolet radiation within the cavity, and a controller for enabling the ultraviolet radiation source to be activated only when the cover is closed.
摘要翻译：提供了一种用于消毒便携式电子设备的消毒剂，该消毒器具有包括用于接收该电子设备的空腔的底座，至少一个用于将紫外线辐射射入空腔的紫外线辐射源，与该基座配合的盖子，打开位置，其中电子设备可以插入到空腔中或从空腔中移除，并且关闭位置，其中空腔被封闭以便基本上保持空腔内的紫外线辐射，以及用于仅使紫外线辐射源仅被激活的控制器当盖子关闭时。

5. 外观设计

USD264908S Combined cup dispenser and straw holder 失效
公开(公告)号：USD264908S
公开(公告)日：1982-06-15
申请号：US153432
申请日：1980-05-27
申请人： Jonathan Cooper
设计人： Jonathan Cooper

6. 发明授权

US09375896B2 Polymeric label material 有权
标题翻译：聚合物标签材料
公开(公告)号：US09375896B2
公开(公告)日：2016-06-28
申请号：US13813303
申请日：2011-07-27
申请人： Jonathan Cooper , Mark Grimbley , Bharath Chandra , Vijay Yadav
发明人： Jonathan Cooper , Mark Grimbley , Bharath Chandra , Vijay Yadav
IPC分类号： B32B7/12 , B32B27/32 , G09F3/10 , B32B7/02 , B32B27/08 , B32B27/20
CPC分类号： B32B7/12 , B32B7/02 , B32B27/08 , B32B27/205 , B32B27/32 , B32B2255/10 , B32B2307/518 , B32B2307/72 , B32B2307/75 , B32B2519/00 , G09F3/10 , Y10T156/10 , Y10T428/249983
摘要： A label material for use with water-based adhesives. The label material includes a synthetic paper having an upper surface and a lower surface. The synthetic paper includes a biaxially-oriented polymeric sheet having a voided layer. A printable coating is optionally provided on an upper surface of the polymeric sheet and an adhesive-receiving coating is provided on a lower surface of the polymeric sheet. The polymeric sheet has a density of not more than 0.55 g·cm−3. The adhesive-receiving coating includes a polymeric binder and an absorbent pigment and has a surface energy of at least 40 dyne·cm−1.
摘要翻译：用于水性胶粘剂的标签材料。标签材料包括具有上表面和下表面的合成纸。合成纸包括具有空隙层的双轴取向聚合物片材。任选地在聚合物片材的上表面上提供可印刷涂层，并且在聚合物片材的下表面上提供粘合剂接收涂层。聚合物片材的密度不大于0.55g·cm -3。粘合剂接收涂层包括聚合物粘合剂和吸收性颜料，并且具有至少40达因厘米-1的表面能。

7. 发明授权

US07970496B2 System and method for provisioning a vehicle interface module 有权
标题翻译：用于配置车辆接口模块的系统和方法
公开(公告)号：US07970496B2
公开(公告)日：2011-06-28
申请号：US12852047
申请日：2010-08-06
申请人： Gerhard Koepf , Robert Yandrofski , Roy G. Perry , Jonathan Cooper
发明人： Gerhard Koepf , Robert Yandrofski , Roy G. Perry , Jonathan Cooper
IPC分类号： G06F7/00 , G01M17/00
CPC分类号： G06F11/25 , G06F11/273 , G07C5/008
摘要： The present invention provides systems and methods for provisioning a vehicle interface module comprising receiving a VIM from a VIM manufacturer and entering appropriate VIM data into a dealer inventory, activating a SIM card for the VIM and installing the VIM in a predetermined vehicle, selecting a wireless activated VIM from the dealer inventory and connecting the VIM to an OBD-II port of the vehicle, connecting a configuration PC to the VIM and downloading a modem configuration, selecting and downloading a vehicle-specific configuration file, accessing a telematics services provider's web portal, entering appropriate vehicle data, and associating the vehicle with the VIM, installing the VIM in the predetermined vehicle, and conducting an installation verification test.
摘要翻译：本发明提供用于提供车辆接口模块的系统和方法，包括从VIM制造商接收VIM并将合适的VIM数据输入经销商库存，激活用于VIM的SIM卡并将VIM安装在预定车辆中，选择无线从经销商库存中激活VIM，并将VIM连接到车辆的OBD-II端口，将配置PC连接到VIM并下载调制解调器配置，选择和下载特定于车辆的配置文件，访问远程信息处理服务提供商的门户网站，输入适当的车辆数据，并将车辆与VIM相关联，将VIM安装在预定车辆中，并进行安装验证测试。

8. 发明授权

US06393748B1 Sign support system 有权
标题翻译：签署支持系统
公开(公告)号：US06393748B1
公开(公告)日：2002-05-28
申请号：US09571375
申请日：2000-05-15
申请人： Jonathan Cooper
发明人： Jonathan Cooper
IPC分类号： G09F718
CPC分类号： G09F15/0056 , G09F7/18
摘要： The system includes a plurality of parallel vertically disposed end support structures. Each support structure comprises two vertically disposed support legs. The upper and lower ends of the support legs are connected respectively to each other by upper and lower connecting members that can be extended or collapsed. When the connecting members are both extended the support structure forms a frame support structure and when collapsed, the support legs are in close proximity and parallel to each other, suitable for storage and/or transport. Channel members are removably mounted to the upper and lower ends of the support legs to connect the end support structures to each other when the connecting members of the support legs are extended. A sign panel is mounted between the upper and lower channel members. Optionally, the sign support system has vertically disposed parallel end support members removably mounted to the upper ends of the vertically disposed support legs. A top channel member is provided connecting and removably mounted to the upper ends of the support members. An upper sign panel is removably mounted between the top channel and the opposing upper channel member.
摘要翻译：该系统包括多个平行的垂直设置的端部支撑结构。每个支撑结构包括两个垂直设置的支撑腿。支撑腿的上端和下端分别通过能够延伸或折叠的上部和下部连接构件相互连接。当连接构件都延伸时，支撑结构形成框架支撑结构，并且当折叠时，支撑腿彼此靠近并且彼此平行，适于储存和/或运输。通道构件可拆卸地安装到支撑腿的上端和下端，以在支撑腿的连接构件延伸时将端部支撑结构彼此连接。标记面板安装在上部和下部通道构件之间。可选地，标志支撑系统具有可拆卸地安装到垂直设置的支撑腿的上端的垂直设置的平行端部支撑构件。提供连接并可移除地安装到支撑构件的上端的顶部通道构件。上标志板可拆卸地安装在顶部通道和相对的上部通道构件之间。

9. 外观设计

USD717375S1 Sign post and frame 有权
标题翻译：签署帖子和框架
公开(公告)号：USD717375S1
公开(公告)日：2014-11-11
申请号：US29456145
申请日：2013-05-29
申请人： Jonathan Cooper
设计人： Jonathan Cooper

10. 发明授权

US08415619B2 Methods and systems for mass spectrometry 有权
标题翻译：质谱方法和系统
公开(公告)号：US08415619B2
公开(公告)日：2013-04-09
申请号：US13296793
申请日：2011-11-15
申请人： David R. Goodlett , Scott R. Heron , Jonathan Cooper
发明人： David R. Goodlett , Scott R. Heron , Jonathan Cooper
IPC分类号： H01J49/26 , G01N23/00
CPC分类号： H01J49/0454 , H01J49/0031
摘要： The present invention relates generally to mass spectrometry. The present invention relates more particularly to methods and systems for use in mass spectrometric identification of a variety of analytes, including high molecular weight species such as proteins. One embodiment of the invention is a method for analyzing an analyte. The method includes nebulizing a suspension of the analyte in a solvent with a surface acoustic wave transducer; and performing mass spectrometry on the nebulized suspension. The surface acoustic wave transducer can be used, for example, to transfer non-volatile peptides and proteins (as well as other analyztes, such as oligonucleotides and polymers) to the gas phase at atmospheric pressure. Nebulization using surface acoustic waves can be conducted in a discontinuous or pulsed mode, similar to that used in MALDI, or in a continuous mode, as in ESI.
摘要翻译：本发明一般涉及质谱法。本发明更具体地涉及用于各种分析物（包括高分子量物质如蛋白质）的质谱鉴定中的方法和系统。本发明的一个实施方案是分析分析物的方法。该方法包括将分析物在溶剂中的悬浮液与表面声波换能器雾化; 并对雾化悬浮液进行质谱分析。例如，表面声波换能器可以用于将大气压下的非挥发性肽和蛋白质（以及其它分析物，例如寡核苷酸和聚合物）转移到气相中。使用表面声波的雾化可以以不连续或脉冲模式进行，类似于在MALDI中使用的模式，或者以连续模式进行，如在ESI中。

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