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1. 发明申请

US20080091259A1 Selectively Light Curable Support Members for Medical Devices 审中-公开
标题翻译：医疗器械选择性光固化支架
公开(公告)号：US20080091259A1
公开(公告)日：2008-04-17
申请号：US11955098
申请日：2007-12-12
申请人： James Heggestuen , Thomas Holman , Jan Weber
发明人： James Heggestuen , Thomas Holman , Jan Weber
IPC分类号： A61F2/06
CPC分类号： A61L29/14 , A61F2/88 , A61F2/90 , A61F2/945 , A61F2002/072 , A61M25/0012 , A61M25/0041 , A61M25/005 , A61M2025/0063
摘要： Methods of forming support layers for use in catheters using having a support layer included, and stents incorporating coatings of photosensitive polymerizable resins and stents including fibers coated with photosensitive polymerizable resins. A fiber is coated with a PPC resin and incorporated into a support structure for a catheter. Portions of the PPC are polymerized by exposure to light of a desired wavelength, causing increased rigidity and strength to the polymerized portions. As the PPC is polymerized, the fibers coated by the PPC resins become stronger and change the flexibility of devices incorporating such fibers. Additional embodiments include stents incorporating PPC coatings and methods of using such stents, including polymerizing a PPC coating after inserting a self-expanding or balloon-expandable stent.
摘要翻译：使用包含支撑层的导管形成支撑层的方法，以及包含光敏聚合树脂和支架涂层的支架，包括用光敏聚合树脂涂覆的纤维。纤维被涂覆有PPC树脂并结合到用于导管的支撑结构中。 PPC的部分通过暴露于所需波长的光而聚合，导致聚合部分的刚性和强度增加。当PPC聚合时，由PPC树脂涂覆的纤维变得更强，并且改变掺入这种纤维的装置的柔性。另外的实施方案包括掺入PPC涂层的支架和使用这种支架的方法，包括在插入自扩张或球囊可扩张的支架之后聚合PPC涂层。

2. 发明申请

US20070038176A1 Medical devices with machined layers for controlled communications with underlying regions 审中-公开
标题翻译：具有加工层的医疗设备，用于与底层区域进行控制通信
公开(公告)号：US20070038176A1
公开(公告)日：2007-02-15
申请号：US11174821
申请日：2005-07-05
申请人： Jan Weber , Thomas Holman
发明人： Jan Weber , Thomas Holman
IPC分类号： A61M31/00 , A61M37/00
CPC分类号： A61L27/50
摘要： According to an aspect of the present invention, implantable or insertable medical devices (also referred to as internal medical devices) are provided. These medical devices include at least one machined layer, at least a portion of which is disposed over at least one underlying region (e.g., a therapeutic agent containing region, a catalytic region, etc.). The at least one machined layer contains a plurality of excavated regions which promote the transport of molecular species across the machined layer. An advantage of the present invention is that medical devices are provided, in which the transport of species into the medical device, out of the medical device, or both are controlled, and may be customized, as desired.
摘要翻译：根据本发明的一个方面，提供了可植入或可插入的医疗装置（也称为内部医疗装置）。这些医疗装置包括至少一个加工层，其至少一部分设置在至少一个下部区域（例如，治疗剂容纳区域，催化区域等）上。所述至少一个加工层包含多个挖掘区域，其促进分子物质跨过加工层的运输。本发明的一个优点是提供了医疗装置，其中可以根据需要将物种运送到医疗装置，医疗装置或两者中进行控制，并且可以被定制。

3. 发明申请

US20060271093A1 Fiber mesh controlled expansion balloon catheter 有权
标题翻译：纤维网控膨胀气囊导管
公开(公告)号：US20060271093A1
公开(公告)日：2006-11-30
申请号：US11139253
申请日：2005-05-27
申请人： Thomas Holman , Jan Weber
发明人： Thomas Holman , Jan Weber
IPC分类号： A61M29/00
CPC分类号： A61F2/958 , A61F2/90 , A61F2/954 , A61M25/10 , A61M2025/1081 , A61M2025/1084
摘要： A medical device having a catheter shaft having a distal portion and a proximal portion, a medical balloon co-axially mounted on the distal portion of the catheter shaft and a tubular mesh wrapped around the balloon, wherein the mesh strengthens and reinforced the balloon and may be manipulation to dictate the shape of the balloon and to squeeze the balloon down onto the catheter shaft during deflation of the balloon.
摘要翻译：一种具有导管轴的医疗装置，其具有远侧部分和近端部分，同轴地安装在导管轴的远端部分上的医疗气囊和缠绕在气囊上的管状网状物，其中，网状物加强并加强气囊，并且可以操纵以指示气球的形状并且在气球收缩期间将气囊向下挤压到导管轴上。

4. 发明申请

US20060184112A1 Medical devices 有权
公开(公告)号：US20060184112A1
公开(公告)日：2006-08-17
申请号：US11060093
申请日：2005-02-17
申请人： Daniel Horn , John Chen , Jan Weber , Thomas Holman
发明人： Daniel Horn , John Chen , Jan Weber , Thomas Holman
IPC分类号： A61F2/06
CPC分类号： A61M25/104 , A61F2002/9583 , A61F2250/0068 , A61L29/126 , A61M2025/1086
摘要： Medical devices and related methods are disclosed.

5. 发明申请

US20060182873A1 Medical devices 审中-公开
标题翻译：医疗设备
公开(公告)号：US20060182873A1
公开(公告)日：2006-08-17
申请号：US11060151
申请日：2005-02-17
申请人： Leo Klisch , Jan Weber , Thomas Holman , Scott Schewe , Afsar Ali , Richard Noddin , James Shippy , Karl Jagger , Jan Seppala
发明人： Leo Klisch , Jan Weber , Thomas Holman , Scott Schewe , Afsar Ali , Richard Noddin , James Shippy , Karl Jagger , Jan Seppala
IPC分类号： A61L33/00
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/10 , A61M25/1029 , A61M25/1038 , A61M2025/1031 , A61M2025/1075 , A61M2025/1086 , A61M2025/1088
摘要： Medical devices, for example, those that have balloons, and methods of making the devices are described. In some embodiments, a method includes providing a medical balloon having a first cone portion and a body portion, and removing material from an outer surface the body portion of the balloon such that the balloon includes a first region and a second region, the first region being recessed relative to the second region.
摘要翻译：描述了医疗设备，例如具有气球的设备，以及制造设备的方法。在一些实施例中，一种方法包括提供具有第一锥形部分和主体部分的医疗气囊，以及从球囊的主体部分的外表面移除材料，使得球囊包括第一区域和第二区域，第一区域相对于第二区域凹进。

6. 发明申请

US20060142798A1 Device and method for closing an opening in a body cavity or lumen 审中-公开
标题翻译：关闭体腔或内腔中的开口的装置和方法
公开(公告)号：US20060142798A1
公开(公告)日：2006-06-29
申请号：US11023055
申请日：2004-12-27
申请人： Thomas Holman , Tracee Eidenschink , Jan Weber
发明人： Thomas Holman , Tracee Eidenschink , Jan Weber
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00234 , A61B2017/00243 , A61B2017/00637 , A61B2017/00659
摘要： A closure device or system seals or closes an opening in a body cavity. The closure device is deployed proximate to an entry site to the body cavity. A needle or instrument is inserted through the closure to form an incision through the body wall to insert a treatment device or instrument. Following withdrawal of the treatment device or instrument, the closure device seals or closes the incision.
摘要翻译：闭合装置或系统密封或封闭体腔中的开口。闭合装置靠近体腔的入口部分展开。针或器械通过封闭物插入通过体壁形成切口以插入治疗装置或器械。在取出治疗装置或器械后，封闭装置密封或闭合切口。

7. 发明申请

US20060136042A1 Vulnerable plaque stent 审中-公开
标题翻译：易损斑块支架
公开(公告)号：US20060136042A1
公开(公告)日：2006-06-22
申请号：US11020537
申请日：2004-12-22
申请人： Thomas Holman , Jan Weber , Graig Kveen
发明人： Thomas Holman , Jan Weber , Graig Kveen
IPC分类号： A61F2/90
CPC分类号： A61F2/07 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/075 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2002/91575 , A61F2220/0058 , A61F2230/0013 , A61L31/024
摘要： A tubular, expandable prosthesis comprises a framework with a plurality of openings therethrough and a carbon nanotube sheet. The carbon nanotube sheet extends across at least one of the openings.
摘要翻译：管状可扩张假体包括具有穿过其中的多个开口的框架和碳纳米管片。碳纳米管片延伸穿过至少一个开口。

8. 发明申请

US20060052767A1 Catheter distal tip design and method of making 有权
公开(公告)号：US20060052767A1
公开(公告)日：2006-03-09
申请号：US11262690
申请日：2005-10-31
申请人： Jan Weber , Thomas Holman
发明人： Jan Weber , Thomas Holman
IPC分类号： A61M25/00
CPC分类号： A61M25/0068 , A61M25/001 , A61M25/008 , A61M2025/0081 , A61M2025/1093 , B23K2103/42 , B23K2103/50
摘要： A catheter comprises a catheter shaft having a distal tip, the distal tip having an inner surface and an outer surface, the inner surface having a rounded profile. The catheter may be made by rounding the inner surface of the distal tip.

9. 发明授权

US08049137B2 Laser shock peening of medical devices 失效
标题翻译：医疗器械的激光冲击硬化
公开(公告)号：US08049137B2
公开(公告)日：2011-11-01
申请号：US10778841
申请日：2004-02-13
申请人： Thomas Holman , Jan Weber
发明人： Thomas Holman , Jan Weber
IPC分类号： B23K26/00
CPC分类号： C21D10/005 , A61F2/91 , A61F2250/0068
摘要： A laser shock peening process for producing one or more compressive residual stress regions in a medical device is disclosed. A high-energy laser apparatus can be utilized to direct an intense laser beam through a confining medium and onto the target surface of a workpiece. An absorption overlay disposed on the target surface of the workpiece absorbs the laser beam, inducing a pressure shock wave that forms a compressive residual stress region deep within the workpiece. Medical devices such as stents and guidewires having one or more of these compressive residual stress regions are also disclosed.
摘要翻译：公开了一种用于在医疗装置中产生一个或多个压缩残余应力区域的激光冲击硬化方法。可以使用高能激光装置将强激光束引导通过约束介质和工件的目标表面。设置在工件的目标表面上的吸收层吸收激光束，引起在工件内部形成压缩残余应力区域的压力冲击波。还公开了具有这些压缩残余应力区域中的一个或多个的支架和导线的医疗装置。

10. 发明申请

US20070208408A1 Non-foreshortening sheaths and assemblies for use 审中-公开
标题翻译：非缩短护套和组件使用
公开(公告)号：US20070208408A1
公开(公告)日：2007-09-06
申请号：US11368913
申请日：2006-03-06
申请人： Jan Weber , Thomas Holman
发明人： Jan Weber , Thomas Holman
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2/966 , A61F2002/91541 , A61F2002/91558 , A61F2210/0076 , A61F2230/0013
摘要： A catheter assembly comprises a catheter shaft having a device receiving portion, an expandable balloon disposed about the device receiving portion, and a sheath. The sheath has an outer surface and an inner surface defining an inner lumen. The outer surface and inner surface has a sheath wall extending there between. The outer surface has slits therethrough which extend into the sheath wall. The sheath has an expanded state and an unexpanded state such that the sheath maintains the substantially same longitudinal length in the expanded state and the unexpanded state.
摘要翻译：导管组件包括具有装置接收部分的导管轴，围绕装置接收部分设置的可膨胀气囊和护套。护套具有限定内腔的外表面和内表面。外表面和内表面具有在其之间延伸的护套壁。外表面具有穿过其的狭缝，其延伸到鞘壁中。鞘具有膨胀状态和未膨胀状态，使得护套在膨胀状态和未膨胀状态下保持基本相同的纵向长度。

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