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1. 发明授权

US4578386A 7,8-Dihydroimidazo[1,5-a]pyrazin-8-ones 失效
标题翻译： 7,8-二氢咪唑并[1,5-a]吡嗪-8-酮
公开(公告)号：US4578386A
公开(公告)日：1986-03-25
申请号：US578916
申请日：1984-02-10
申请人： Thomas D. Lee
发明人： Thomas D. Lee
IPC分类号： A61K31/495 , A61P9/00 , C07D233/92 , C07D403/06 , C07D487/04 , A61K31/50 , A61K31/53 , C07D519/00
CPC分类号： C07D233/92 , C07D403/06 , C07D487/04
摘要： Provided are compounds of the structure: ##STR1## wherein R.sub.1, R.sub.3, R.sub.5 and R.sub.6 are independently H, alkyl, aralkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkenyl, alkynyl, hydroxy, hydroxyalkyl, alkoxy, mercapto, mercaptoalkyl, alkylthio, amino, alkylamino, aminoalkyl, formyl, carboxy and salts thereof, carbalkoxy, alkanoyl, cyano, nitro, halo, trifluoromethyl, alkylsulfonyl, aminosulfonyl, carbamoyl or cycloalkyl; andR.sub.7 is H, alkyl, aryl, aralkyl, oxo, or alkanoyl;wherein at least one of R.sub.1 R.sub.5 or R.sub.6 is an aryl, heteroaryl, or heteroaryl substituted with H, alkyl, halo, amino, trifluoromethyl or cyano.
摘要翻译：提供以下结构的化合物：其中R1，R3，R5和R6独立地为H，烷基，芳烷基，芳基，取代的芳基，杂芳基，取代的杂芳基，烯基，炔基，羟基，羟烷基，烷氧基，巯基，巯基烷基，烷硫基，氨基，烷基氨基，氨基烷基，甲酰基，羧基及其盐，烷氧基，烷酰基，氰基，硝基，卤素，三氟甲基，烷基磺酰基，氨基磺酰基，氨基甲酰基或环烷基; 并且R 7是H，烷基，芳基，芳烷基，氧代或烷酰基; 其中R 1 + L，R 5或R 6中的至少一个是被H，烷基，卤素，氨基，三氟甲基或氰基取代的芳基，杂芳基或杂芳基。

2. 发明授权

US6126981A Ready-to-drink, aspartame-sweetened beverages 失效
标题翻译：即食饮料，阿斯巴甜甜味饮料
公开(公告)号：US6126981A
公开(公告)日：2000-10-03
申请号：US268708
申请日：1994-06-30
申请人： Thomas D. Lee , Robert W. Wood
发明人： Thomas D. Lee , Robert W. Wood
IPC分类号： A23L2/56 , A23L2/60 , A23L2/68 , A23L2/38
CPC分类号： A23L2/68 , A23L2/56 , A23L2/60
摘要： Ready-to-drink, aspartame-sweetened beverages having longer shelf-life are prepared by raising the pH of the beverage to above 3.2 while maintaining a sour taste which is equivalent to a beverage having a pH of 2.9. The beverage of this invention are formulated with a citric acid to citrate buffer salt ratio (by weight) of 2.5-4.3:1.
摘要翻译：通过将饮料的pH提高到3.2以上，同时保持相当于pH为2.9的饮料的酸味，制备具有更长保质期的即食饮料，阿斯巴甜甜味饮料。本发明的饮料以2.5-4.3:1的柠檬酸与柠檬酸盐缓冲盐比（重量比）配制。

3. 发明授权

US4510151A Pyridinylimidazole pharmaceutical composition 失效
标题翻译：吡啶基咪唑药物组合物
公开(公告)号：US4510151A
公开(公告)日：1985-04-09
申请号：US578918
申请日：1984-02-10
申请人： Thomas D. Lee
发明人： Thomas D. Lee
IPC分类号： C07D401/04 , A61K31/44
CPC分类号： C07D401/04
摘要： A pharmaceutical composition containing a therapeutically effective amount of a pyridinylimidazole 4- or 5-substituted carboxylic acid and esters thereof is provided to treat cardiovascular ailment.
摘要翻译：提供含有治疗有效量的吡啶基咪唑4-或5-取代的羧酸及其酯的药物组合物以治疗心血管疾病。

4. 发明授权

US06977387B2 Combined on-axis and off-axis illumination 失效
标题翻译：组合的轴上和离轴照明
公开(公告)号：US06977387B2
公开(公告)日：2005-12-20
申请号：US10794283
申请日：2004-03-04
申请人： Thomas D. Lee
发明人： Thomas D. Lee
IPC分类号： G02B5/00 , G03F7/20 , H01J37/09
CPC分类号： G03F7/70091 , G02B5/005
摘要： The present invention describes an aperture comprising an opaque plate with a central opening and at least one peripheral opening and a method for combining an on-axis component and at least one off-axis component of illumination light.
摘要翻译：本发明描述了一种孔，其包括具有中心开口和至少一个外围开口的不透明板，以及用于组合轴上分量和照明光的至少一个离轴分量的方法。

5. 发明授权

US5145707A Salt enhancer 失效
标题翻译：盐增强剂
公开(公告)号：US5145707A
公开(公告)日：1992-09-08
申请号：US807038
申请日：1991-12-12
申请人： Thomas D. Lee
发明人： Thomas D. Lee
IPC分类号： A23L27/21 , A23L27/40
CPC分类号： A23L27/40 , A23L27/21
摘要： An edible salt enhancing composition is provided which is a combination of L-aspartic acid and L-arginine and sodium chloride.
摘要翻译：提供了一种食盐增强组合物，其是L-天冬氨酸和L-精氨酸和氯化钠的组合。

6. 发明授权

US07052725B2 Calcium-supplemented beverages and method of making same 有权
公开(公告)号：US07052725B2
公开(公告)日：2006-05-30
申请号：US09982180
申请日：2001-10-16
申请人： Pei K. Chang , Thomas D. Lee , John Olszewski , Brenton G. Edgar , Richard Orr , Helen Curtiss
发明人： Pei K. Chang , Thomas D. Lee , John Olszewski , Brenton G. Edgar , Richard Orr , Helen Curtiss
IPC分类号： A23L1/304 , A23L2/60
CPC分类号： A23L2/385 , A23L2/52 , A23L33/16 , A23V2002/00 , A23V2250/032 , A23V2250/2482 , A23V2250/1578
摘要： Methods for making artificially sweetened calcium fortified beverages and beverage concentrates, and the stable beverage and beverage concentrates formed thereby; calcium-supplemented beverages and beverage concentrates comprising a unique blend of calcium salts.

7. 发明授权

US06738201B2 Combined on-axis and off-axis illumination 有权
公开(公告)号：US06738201B2
公开(公告)日：2004-05-18
申请号：US09823809
申请日：2001-03-30
申请人： Thomas D. Lee
发明人： Thomas D. Lee
IPC分类号： G02B908
CPC分类号： G03F7/70091 , G02B5/005
摘要： The present invention describes an aperture comprising an opaque plate with a central opening and at least one peripheral opening and a method for combining an on-axis component and at least one off-axis component of illumination light.

8. 发明授权

US5176934A Seasoned food product with a salt enhancer 失效
标题翻译：调味食品与盐增强剂
公开(公告)号：US5176934A
公开(公告)日：1993-01-05
申请号：US869973
申请日：1992-04-16
申请人： Thomas D. Lee
发明人： Thomas D. Lee
IPC分类号： A23L27/21 , A23L27/40
CPC分类号： A23L27/40 , A23L27/21
摘要： An edible salt enhancing composition is provided which is a combination of L-aspartic acid and L-arginine and sodium chloride.
摘要翻译：提供了一种食盐增强组合物，其是L-天冬氨酸和L-精氨酸和氯化钠的组合。

9. 发明授权

US4774027A Process for the preparation of N-L-aminodicarboxylic acid esters and new compositions used in the preparation thereof 失效
标题翻译：用于制备N-L-氨基二羧酸酯的方法和用于其制备的新组合物
公开(公告)号：US4774027A
公开(公告)日：1988-09-27
申请号：US119947
申请日：1987-11-13
申请人： Thomas D. Lee
发明人： Thomas D. Lee
IPC分类号： C07K5/072 , C07C117/00
CPC分类号： C07C247/00 , C07K5/06113
摘要： This present invention provides an improved method for producing N-L-aspartyl-D-alanine fenchyl ester or N-L-aspartyl-methylalanine fenchyl ester and new compositions of fenchol derivatives which are intermediate compositions in the preparation of the above described fenchyl esters.
摘要翻译：本发明提供了制备N-L-天冬氨酰-D-丙氨酸ench基酯或N-L-天冬氨酰基 - 甲基丙氨酸蕨酯的改进方法和作为制备上述肟基酯的中间体组合物的新戊烯衍生物组合物。

10. 发明授权

US4124140A Gasketed flange sealer 失效
标题翻译：垫圈法兰密封
公开(公告)号：US4124140A
公开(公告)日：1978-11-07
申请号：US882594
申请日：1978-03-02
申请人： Michael J. Ziegler , Thomas D. Lee
发明人： Michael J. Ziegler , Thomas D. Lee
IPC分类号： B65D39/08 , B65D53/00
CPC分类号： B65D39/084
摘要： A closure for an opening in the surface of a drum or barrel, especially for a drum or barrel which has been reconditioned by heating so that the original gaskets have been burned out of the opening. The closure includes a cylindrical sleeve disposed in the opening and having a threaded inner surface. The threads of an externally threaded cylindrical cap engage the threads of the sleeve. The cap has an annular generally circular lip about its outer periphery and at its outer end, which lip extends perpendicularly to the sleeve adjacent the outer end of the sleeve so that the outer portion of the lip is parallel to the drum surface. A flexible resilient cylindrical gasket is coaxially mounted external to the sleeve so that the gasket lies between the lip and the drum surface. When the cap is screwed inwards into the sleeve, the lip compresses the gasket against the surface of the drum so that the gasket is squeezed and deforms, and thus so that the gasket forms a closure seal against fluid flow out of the drum.
摘要翻译：用于鼓或桶的表面中的开口的封闭件，特别是用于已经通过加热再生的鼓或桶的开口，使得原始垫圈已经从开口中燃烧。封闭件包括设置在开口中并具有螺纹内表面的圆柱形套筒。外螺纹圆柱形盖子的螺纹与套筒的螺纹啮合。盖子围绕其外周边具有环形的大致圆形的唇部，并且在其外端处，该唇缘与套筒的外端垂直地延伸，使唇部的外部部分平行于滚筒表面。柔性弹性圆柱形垫片同轴地安装在套筒的外部，使得垫圈位于唇缘和鼓表面之间。当盖子向内拧入套筒时，唇部将垫圈压靠在滚筒的表面上，使得垫圈被挤压和变形，从而使得垫圈形成封闭密封件，以防止流体流出滚筒。

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