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1. 发明授权

US07970189B2 Method of automatic extraction of the pulmonary artery tree from 3D medical images 有权
标题翻译：从3D医学图像自动提取肺动脉树的方法
公开(公告)号：US07970189B2
公开(公告)日：2011-06-28
申请号：US11815662
申请日：2006-02-06
申请人： Thomas Buelow , Rafael Wiemker , Thomas Blaffert , Cristian Lorenz , Steffen Renisch
发明人： Thomas Buelow , Rafael Wiemker , Thomas Blaffert , Cristian Lorenz , Steffen Renisch
IPC分类号： G06K9/00
CPC分类号： G06T7/155 , G06T7/11 , G06T7/149 , G06T2200/04 , G06T2207/10081 , G06T2207/20044 , G06T2207/20156 , G06T2207/30061 , G06T2207/30101
摘要： An automated method (1) for the automatic extraction of a pulmonary vessel tree from a 3D medical image, such as multi-slice CT data, is disclosed. A segmented pulmonary vessel is identified as either an artery or a vein by determining a measure for arterialness for the vessel. The measure is based on a relation of the orientation of a local bronchus to the orientation of the segmented pulmonary vessel of the local bronchus. When a vessel is identified as a pulmonary artery, it is added to the pulmonary artery tree. Radii of the pulmonary artery and bronchus are measured automatically and positions where a ratio of these radii exhibits unusual values are presented in a display, preferably for suggesting further assessment by a radiologist, which for instance is useful for pulmonary embolism detection.
摘要翻译：公开了一种用于从诸如多层CT数据的3D医学图像自动提取肺血管树的自动化方法（1）。通过确定血管动脉的测量，将分段的肺血管识别为动脉或静脉。该措施基于局部支气管的取向与局部支气管的分段肺血管的取向的关系。当血管被识别为肺动脉时，将其加入肺动脉树。自动测量肺动脉和支气管的半径，并且在显示中呈现这些半径的比率显示出异常值的位置，优选用于暗示例如用于肺栓塞检测的放射科医师的进一步评估。

2. 发明申请

US20100128940A1 METHOD OF AUTOMATIC EXTRACTION OF THE PULMONARY ARTERY TREE FROM 3D MEDICAL IMAGES 有权
标题翻译：从三维医学图像中自动提取脉络膜的方法
公开(公告)号：US20100128940A1
公开(公告)日：2010-05-27
申请号：US11815662
申请日：2006-02-06
申请人： Thomas Buelow , Rafael Wiemker , Thomas Blaffert , Cristian Lorenz , Steffen Renisch
发明人： Thomas Buelow , Rafael Wiemker , Thomas Blaffert , Cristian Lorenz , Steffen Renisch
IPC分类号： G06K9/62
CPC分类号： G06T7/155 , G06T7/11 , G06T7/149 , G06T2200/04 , G06T2207/10081 , G06T2207/20044 , G06T2207/20156 , G06T2207/30061 , G06T2207/30101
摘要： An automated method (1) for the automatic extraction of a pulmonary vessel tree from a 3D medical image, such as multi-slice CT data, is disclosed. A segmented pulmonary vessel is identified as either an artery or a vein by determining a measure for arterialness for the vessel. The measure is based on a relation of the orientation of a local bronchus to the orientation of the segmented pulmonary vessel of the local bronchus. When a vessel is identified as a pulmonary artery, it is added to the pulmonary artery tree. Radii of the pulmonary artery and bronchus are measured automatically and positions where a ratio of these radii exhibits unusual values are presented in a display, preferably for suggesting further assessment by a radiologist, which for instance is useful for pulmonary embolism detection.
摘要翻译：公开了一种用于从诸如多层CT数据的3D医学图像自动提取肺血管树的自动化方法（1）。通过确定血管动脉的测量，将分段的肺血管识别为动脉或静脉。该措施基于局部支气管的取向与局部支气管的分段肺血管的取向的关系。当血管被识别为肺动脉时，将其加入肺动脉树。自动测量肺动脉和支气管的半径，并且在显示中呈现这些半径的比率显示出异常值的位置，优选用于暗示例如用于肺栓塞检测的放射科医师的进一步评估。

3. 发明申请

US20080071160A1 Displaying A Tracheobronchial Tree 审中-公开
标题翻译：显示气管支气管树
公开(公告)号：US20080071160A1
公开(公告)日：2008-03-20
申请号：US11570517
申请日：2005-06-15
申请人： Rafael Wiemker , Thomas Blaffert , Thomas Buelow , Steffen Renisch , Cristian Lorenz , Hans-Aloys Wischmann
发明人： Rafael Wiemker , Thomas Blaffert , Thomas Buelow , Steffen Renisch , Cristian Lorenz , Hans-Aloys Wischmann
IPC分类号： A61B5/04
CPC分类号： G06T11/206 , G06T7/12 , G06T7/62 , G06T2207/10072 , G06T2207/30028 , G06T2207/30061
摘要： The invention relates to automatically segmenting and displaying the tracheobronchial tree (400) and displaying clinical values (404) related to the segmented tracheobronchial tree (400).
摘要翻译：本发明涉及自动分割和显示气管支气管（400）并显示与分段的气管支气管结石（400）相关的临床值（404）。

4. 发明授权

US08892188B2 Identifying abnormal tissue in images of computed tomography 有权
标题翻译：识别计算机断层扫描图像中的异常组织
公开(公告)号：US08892188B2
公开(公告)日：2014-11-18
申请号：US11815973
申请日：2006-02-03
申请人： Thomas Buelow , Rafael Wiemker , Cristian Lorenz , Steffen Renisch , Thomas Blaffert
发明人： Thomas Buelow , Rafael Wiemker , Cristian Lorenz , Steffen Renisch , Thomas Blaffert
IPC分类号： A61B6/03 , G06T7/00 , G06K9/34 , A61B6/00
CPC分类号： G06T7/0012 , A61B6/032 , A61B6/481 , A61B6/5217 , G06T5/50 , G06T7/10 , G06T7/12 , G06T7/149 , G06T2207/10081 , G06T2207/10116 , G06T2207/30061 , G06T2207/30064 , G06T2207/30101
摘要： An imaging method for identifying abnormal tissue in the lung is provided, comprising the recording of slice images of the lung by means of X-ray radiation, recording of blood vessels, differentiation of blood vessels and abnormal tissue, segmentation of the abnormal tissue and display of the segmented abnormal tissue on an output device. In addition, a computer tomograph for identifying abnormal tissue in the lung is provided, having a radiation source for recording slice images of the lung and blood vessels by means of X-ray radiation, a computer unit for differentiating the blood vessels from the abnormal tissue and for segmenting the abnormal tissue, as well as an output device for displaying the segmented abnormal tissue. Furthermore, a computer program is provided for controlling a computer tomograph for an identification of abnormal tissue in the lung by means of a radiation source, designed to record slice images of the lung and blood vessels by means of X-ray radiation, to differentiate the blood vessels from abnormal tissue, to segment the abnormal tissue and to control an output device for displaying the abnormal tissue.
摘要翻译：提供了一种用于鉴定肺中异常组织的成像方法，包括通过X射线照射记录肺的切片图像，记录血管，血管和异常组织的分化，异常组织的分割和显示的输出装置上的分段异常组织。另外，提供了一种用于识别肺中的异常组织的计算机断层摄影机，具有用于通过X射线辐射记录肺和血管的切片图像的辐射源，用于将血管与异常组织分离的计算机单元并且用于分割异常组织，以及用于显示分段的异常组织的输出装置。此外，提供了一种计算机程序，用于通过辐射源来控制用于识别肺中的异常组织的计算机断层摄影机，其被设计成通过X射线辐射记录肺和血管的切片图像，以区分来自异常组织的血管，分割异常组织并控制用于显示异常组织的输出装置。

5. 发明申请

US20080269598A1 Identifying Abnormal Tissue in Images of Computed Tomography 有权
标题翻译：识别计算机断层扫描图像中的异常组织
公开(公告)号：US20080269598A1
公开(公告)日：2008-10-30
申请号：US11815973
申请日：2006-02-03
申请人： Thomas Buelow , Rafael Wiemker , Cristian Lorenz , Steffen Renisch , Thomas Blaffert
发明人： Thomas Buelow , Rafael Wiemker , Cristian Lorenz , Steffen Renisch , Thomas Blaffert
IPC分类号： A61B5/05 , G06K9/00
CPC分类号： G06T7/0012 , A61B6/032 , A61B6/481 , A61B6/5217 , G06T5/50 , G06T7/10 , G06T7/12 , G06T7/149 , G06T2207/10081 , G06T2207/10116 , G06T2207/30061 , G06T2207/30064 , G06T2207/30101
摘要： An imaging method for identifying abnormal tissue in the lung is provided, comprising the recording of slice images of the lung by means of X-ray radiation, recording of blood vessels, differentiation of blood vessels and abnormal tissue, segmentation of the abnormal tissue and display of the segmented abnormal tissue on an output device. In addition, a computer tomograph for identifying abnormal tissue in the lung is provided, having a radiation source for recording slice images of the lung and blood vessels by means of X-ray radiation, a computer unit for differentiating the blood vessels from the abnormal tissue and for segmenting the abnormal tissue, as well as an output device for displaying the segmented abnormal tissue. Furthermore, a computer program is provided for controlling a computer tomograph for an identification of abnormal tissue in the lung by means of a radiation source, designed to record slice images of the lung and blood vessels by means of X-ray radiation, to differentiate the blood vessels from abnormal tissue, to segment the abnormal tissue and to control an output device for displaying the abnormal tissue.
摘要翻译：提供了一种用于鉴定肺中异常组织的成像方法，包括通过X射线照射记录肺的切片图像，记录血管，血管和异常组织的分化，异常组织的分割和显示的输出装置上的分段异常组织。另外，提供了一种用于识别肺中的异常组织的计算机断层摄影机，具有用于通过X射线辐射记录肺和血管的切片图像的辐射源，用于将血管与异常组织分离的计算机单元并且用于分割异常组织，以及用于显示分段的异常组织的输出装置。此外，提供了一种计算机程序，用于通过辐射源来控制用于识别肺中的异常组织的计算机断层摄影机，其被设计成通过X射线辐射记录肺和血管的切片图像，以区分来自异常组织的血管，分割异常组织并控制用于显示异常组织的输出装置。

6. 发明申请

US20110052018A1 APPARATUS FOR SEGMENTING AN OBJECT COMPRISING SUB-OBJECTS 有权
标题翻译：用于分配包含子对象的对象的设备
公开(公告)号：US20110052018A1
公开(公告)日：2011-03-03
申请号：US12867522
申请日：2009-02-06
申请人： Thomas Blaffert , Hans Barschdorf , Jans Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
发明人： Thomas Blaffert , Hans Barschdorf , Jans Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
IPC分类号： G06K9/00 , G06K9/34
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

7. 发明授权

US08526697B2 Apparatus for segmenting an object comprising sub-objects 有权
标题翻译：用于分割包括子对象的对象的装置
公开(公告)号：US08526697B2
公开(公告)日：2013-09-03
申请号：US12867522
申请日：2009-02-06
申请人： Thomas Blaffert , Hans Barschdorf , Jens Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
发明人： Thomas Blaffert , Hans Barschdorf , Jens Von Berg , Sebastian Peter Michael Dries , Cristian Lorenz , Rafael Wiemker , Tobias Klinder , Astrid Ruth Franz , Steffen Renisch
IPC分类号： G06K9/00
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

8. 发明申请

US20110286652A1 SYSTEM FOR PROVIDING LUNG VENTILATION INFORMATION 有权
标题翻译：提供肺通气信息的系统
公开(公告)号：US20110286652A1
公开(公告)日：2011-11-24
申请号：US13146885
申请日：2010-01-25
申请人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
发明人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
IPC分类号： G06K9/00
CPC分类号： A61B6/5235 , A61B5/08 , A61B6/541 , G06T7/33 , G06T2207/10081 , G06T2207/30061
摘要： A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).
摘要翻译：一种用于显示肺通气信息的系统，所述系统包括输入（12）和处理单元（15）。所述输入被提供用于接收肺的多个CT图像（71），每个CT图像（71）对应于呼吸周期中的至少两个不同相的一个相。所述处理单元（15）被配置为比较对应于呼吸周期中的不同相位的CT图像（71），以确定每个相位的变形矢量场，以根据相应的变形矢量为每个阶段生成通气图像（72）在空间上对准通气图像（72），并且为每个对齐的通气图像（72）中的至少一个公共位置（62）产生一个通风值的时间过程的功能（81），用于所述公共位置（62）中，所述功能（81）中的每个换气值基于对应于对齐的通气图像（73）的变形矢量场。

9. 发明授权

US08798343B2 System for providing lung ventilation information 有权
标题翻译：提供肺通气信息的系统
公开(公告)号：US08798343B2
公开(公告)日：2014-08-05
申请号：US13146885
申请日：2010-01-25
申请人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
发明人： Sven Kabus , Cristian Lorenz , Nicole Schadewaldt , Roland Opfer , Ingwer Curt Carlsen , Steffen Renisch , Joerg Sabczynski , Hans Barschdorf , Jens Von Berg , Thomas Blaffert , Tobias Klinder
IPC分类号： G06K9/00
CPC分类号： A61B6/5235 , A61B5/08 , A61B6/541 , G06T7/33 , G06T2207/10081 , G06T2207/30061
摘要： A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).
摘要翻译：一种用于显示肺通气信息的系统，所述系统包括输入（12）和处理单元（15）。所述输入被提供用于接收肺的多个CT图像（71），每个CT图像（71）对应于呼吸周期中的至少两个不同相的一个相。所述处理单元（15）被配置为比较对应于呼吸周期中的不同相位的CT图像（71），以确定每个相位的变形矢量场，以根据相应的变形矢量为每个阶段生成通气图像（72）在空间上对准通气图像（72），并且为每个对齐的通气图像（72）中的至少一个公共位置（62）产生功能（81），其中通风值的时间过程为所述公共位置（62）中，所述功能（81）中的每个换气值基于对应于对齐的通气图像（73）的变形矢量场。

10. 发明申请

US20100149214A1 RENDERING A VIEW FROM AN IMAGE DATASET 有权
标题翻译：从图像数据库渲染视图
公开(公告)号：US20100149214A1
公开(公告)日：2010-06-17
申请号：US12063111
申请日：2006-08-10
申请人： Rafael Wiemker , Thomas Buelow , Thomas Blaffert
发明人： Rafael Wiemker , Thomas Buelow , Thomas Blaffert
IPC分类号： G09G5/00
CPC分类号： G06T19/00 , G06T2210/41 , G06T2219/008
摘要： The invention relates to a rendering system (100) for rendering a view from an image dataset, the rendering system comprising a selecting unit (110) for selecting a subset of the image dataset, a computing unit (120) for computing a first principal axis of a tensor on the basis of the subset of the image dataset, and a rendering unit (130) for rendering the view on the basis of the first principal axis. Using the information about the directionality and orientation of a structure, comprised in the selected subset of the image dataset and extracted from the first principal axis of the tensor, the rendering system (100) is arranged to effectively assist the user in selecting an advantageous view from the image dataset.
摘要翻译：本发明涉及一种用于从图像数据集呈现视图的渲染系统（100），所述绘制系统包括用于选择所述图像数据集的子集的选择单元（110），用于计算第一主轴的计算单元（120）基于所述图像数据集的子集的张量，以及用于基于所述第一主轴渲染所述视图的渲染单元（130）。使用包括在所述图像数据集的所选择的子集中并从所述张量的所述第一主轴提取的结构的方向性和取向的信息，所述呈现系统（100）被布置为有效地帮助所述用户选择有利视图从图像数据集。

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