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1. 发明申请

US20060120507A1 Angiographic x-ray diagnostic device for rotation angiography 有权
标题翻译：用于旋转血管造影的血管造影X线诊断装置
公开(公告)号：US20060120507A1
公开(公告)日：2006-06-08
申请号：US11284235
申请日：2005-11-21
申请人： Thomas Brunner , Klaus Klingenbeck-Regn , Michael Maschke , Alois Nottling , Ernst-Peter Ruhrnschopf , Bernhard Scholz , Bernd Schreiber , Norbert Strobel , Karl Wiesent , Michael Zellerhoff
发明人： Thomas Brunner , Klaus Klingenbeck-Regn , Michael Maschke , Alois Nottling , Ernst-Peter Ruhrnschopf , Bernhard Scholz , Bernd Schreiber , Norbert Strobel , Karl Wiesent , Michael Zellerhoff
IPC分类号： G01N23/04
CPC分类号： G06T11/005 , A61B6/466 , A61B6/504 , G06T2211/404
摘要： The invention relates to an angiographic x-ray diagnostic device for rotation angiography with an x-ray emitter which can be moved on a circular path about a patient located on a patient support table, with an image detector unit which can moved on the circular path facing the x-ray emitter, with a digital image system for recording a plurality of projection images by means of rotation angiography, with a device for image processing, by means of which the projection images are reconstructed into a 3D volume image, and with a device for correcting physical effects and/or inadequacies in the recording system such as truncation correction, scatter correction, ring artifact correction, correction of the beam hardening and/or of the low frequency drop for the soft tissue display of projection images and the 3D volume images resulting therefrom.
摘要翻译：本发明涉及一种用X射线发射器进行旋转血管造影的血管造影X射线诊断装置，该X射线发射器可以围绕位于病人支撑台上的患者的圆形路径移动，图像检测器单元可在圆形路径上移动面对x射线发射器，具有用于通过旋转血管造影记录多个投影图像的数字图像系统，具有用于图像处理的装置，通过该装置将投影图像重建成3D体积图像，并且利用用于校正记录系统的物理效应和/或不足的装置，例如用于投影图像的软组织显示的截断校正，散射校正，环形伪影校正，光束硬化的校正和/或低频率下降的3D体积由此产生的图像。

2. 发明授权

US09700276B2 Robust multi-object tracking using sparse appearance representation and online sparse appearance dictionary update 有权
公开(公告)号：US09700276B2
公开(公告)日：2017-07-11
申请号：US13780149
申请日：2013-02-28
申请人： Lei Zhang , Wen Wu , Terrence Chen , Norbert Strobel , Dorin Comaniciu
发明人： Lei Zhang , Wen Wu , Terrence Chen , Norbert Strobel , Dorin Comaniciu
IPC分类号： A61B1/04 , A61B1/00 , A61B6/00 , A61B6/12 , G06T7/246 , A61B90/00 , A61B34/20
CPC分类号： A61B6/5211 , A61B6/12 , A61B6/485 , A61B6/487 , A61B2034/2065 , A61B2090/376 , G06T7/248 , G06T2207/30021
摘要： A computer-implemented method for tracking one or more objects in a sequence of images includes generating a dictionary based on object locations in a first image included in the sequence of images. One or more object landmark candidates are identified in the sequence of images and a plurality of tracking hypothesis for the object landmark candidates are generated. A first tracking hypothesis is selected from the plurality of tracking hypothesis based on the dictionary.

3. 发明授权

US08989463B2 Localization and tracking of cryo-balloon during interventional fluoroscopy imaging 有权
标题翻译：介入性透视成像期间冷冻球囊的定位和跟踪
公开(公告)号：US08989463B2
公开(公告)日：2015-03-24
申请号：US13551902
申请日：2012-07-18
申请人： Julien Christian Barbot , Atilla Peter Kiraly , Norbert Strobel
发明人： Julien Christian Barbot , Atilla Peter Kiraly , Norbert Strobel
IPC分类号： G06K9/00 , G06T7/00
CPC分类号： G06T7/0085 , G06T7/0012 , G06T7/13 , G06T7/181 , G06T7/75 , G06T2207/10121 , G06T2207/30021
摘要： A method for the detection of a balloon catheter within a fluoroscopic image, including: removing noise from a fluoroscopic image; detecting edges of a balloon catheter in the fluoroscopic image, wherein the detected edges include subsets of connected edges; extracting an edge subset from the subsets of connected edges; fitting a model to the extracted edge subset; removing outliers of the extracted edge subset based on the fitting of the model; adding the extracted edge subset without the outlier to a data set; repeating the extracting, fitting, removing and adding steps for the remainder of the subsets of connected edges; and fitting the model to the data set, wherein the data set is indicative of the balloon catheter.
摘要翻译：一种用于检测透视图像内的气囊导管的方法，包括：从透视图像中去除噪声; 在透视图像中检测气囊导管的边缘，其中检测到的边缘包括连接边缘的子集; 从连接边缘的子集中提取边缘子集; 将模型拟合到提取的边缘子集; 基于模型的拟合来去除提取的边缘子集的异常值; 将所提取的边缘子集不带异常值添加到数据集; 重复连续边缘子集的其余部分的提取，拟合，移除和添加步骤; 以及将所述模型拟合到所述数据集，其中所述数据集指示所述球囊导管。

4. 发明授权

US08675996B2 Catheter RF ablation using segmentation-based 2D-3D registration 有权
标题翻译：使用基于分割的2D-3D注册的导管RF消融
公开(公告)号：US08675996B2
公开(公告)日：2014-03-18
申请号：US12821235
申请日：2010-06-23
申请人： Rui Liao , Norbert Strobel , Chenyang Xu
发明人： Rui Liao , Norbert Strobel , Chenyang Xu
IPC分类号： G06K9/32 , G06K9/00
CPC分类号： A61B6/5235 , A61B6/487 , A61B6/504 , A61B6/5247 , A61B18/1492 , A61B90/37 , A61B2090/364 , A61B2090/376 , A61B2090/3764 , G06T3/0068 , G06T7/33 , G06T2207/10072 , G06T2207/10121 , G06T2207/20041 , G06T2207/30048
摘要： A method for registering a two-dimensional image of a cardiocirculatory structure and a three-dimensional image of the cardiocirculatory structure includes acquiring a three-dimensional image including the cardiocirculatory structure using a first imaging modality. The acquired three-dimensional image is projected into two-dimensions to produce a two-dimensional projection image of the cardiocirculatory structure. A structure of interest is segmented either from the three-dimensional image prior to projection or from the projection image subsequent to projection. A two-dimensional image of the cardiocirculatory structure is acquired using a second imaging modality. The structure of interest is segmented from the acquired two-dimensional image. A first distance map is generated based on the two-dimensional projection image and a second distance map is generated based on the acquired two-dimensional image. A registration of the three-dimensional image and the two-dimensional image is performed by minimizing a difference between the first and second distance maps.
摘要翻译：用于记录心脏循环结构的二维图像和心脏循环结构的三维图像的方法包括使用第一成像模式获取包括心脏循环结构的三维图像。所获取的三维图像被投影成二维以产生心脏循环结构的二维投影图像。感兴趣的结构或者从投影之前的三维图像或投影之后的投影图像分割。使用第二成像模式获取心脏循环结构的二维图像。感兴趣的结构从获得的二维图像中分割出来。基于二维投影图像生成第一距离图，并且基于所获取的二维图像生成第二距离图。通过最小化第一和第二距离图之间的差异来执行三维图像和二维图像的配准。

5. 发明申请

US20130282005A1 CATHETER NAVIGATION SYSTEM 审中-公开
标题翻译：导管导航系统
公开(公告)号：US20130282005A1
公开(公告)日：2013-10-24
申请号：US13859115
申请日：2013-04-09
申请人： Martin Koch , Atilla Peter Kiraly , Norbert Strobel , Alexander Benjamin Brost
发明人： Martin Koch , Atilla Peter Kiraly , Norbert Strobel , Alexander Benjamin Brost
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B90/36 , A61B2018/00375 , A61B2018/00577 , A61B2090/065 , A61B2090/364
摘要： An integrated catheter navigation system (100) and method (200) that combines anatomical imaging (302, 304) with catheter tip-to force information (306, 308) during an ablation procedure.
摘要翻译：一种在解剖过程中将解剖学成像（302,304）与导管尖端组合以强制信息（306,308）的集成导管导航系统（100）和方法（200）。

6. 发明授权

US08538106B2 Three-dimensional esophageal reconstruction 有权
标题翻译：三维食管重建
公开(公告)号：US08538106B2
公开(公告)日：2013-09-17
申请号：US12902412
申请日：2010-10-12
申请人： Julian Ibarz , Norbert Strobel , Liron Yatziv
发明人： Julian Ibarz , Norbert Strobel , Liron Yatziv
IPC分类号： G06K9/00
CPC分类号： G06T7/564 , G06K2209/05 , G06T11/006 , G06T17/00 , G06T2207/10116 , G06T2207/10121 , G06T2207/30092 , G06T2207/30172 , G06T2211/412
摘要： A method for three-dimensional esophageal reconstruction includes acquiring a first X-ray image from a first angle with respect to a subject using a first X-ray imager. At least a second X-ray image is acquired from a second angle, different than the first angle, with respect to the subject using a second X-ray imager. Additional X-ray images may be acquired from additional angle. A three-dimensional model of the esophagus is generated from the at least two X-ray images acquired at different angles. A set of fluoroscopic X-ray images is acquired using either the first X-ray imager or the second X-ray imager. The three-dimensional model of the esophagus is registered to the acquired set of fluoroscopic X-ray images. The three-dimensional model of the esophagus is displayed overlaying the set of fluoroscopic X-ray images.
摘要翻译：一种用于三维食管重建的方法包括使用第一X射线成像仪从相对于对象的第一角度获取第一X射线图像。使用第二X射线成像仪相对于被摄体从与第一角度不同的第二角度获取至少第二X射线图像。可以从附加角度获取附加的X射线图像。从不同角度获取的至少两个X射线图像产生食管的三维模型。使用第一X射线成像仪或第二X射线成像仪获取一组荧光X射线图像。食管的三维模型被记录到所获取的荧光X射线图像组中。显示食管的三维模型覆盖了一组荧光X线片。

7. 发明申请

US20130083980A1 LOCALIZATION AND TRACKING OF CRYO-BALLOON DURING INTERVENTIONAL FLUOROSCOPY IMAGING 有权
标题翻译：常规荧光成像过程中CRYO-BALLOON的定位和跟踪
公开(公告)号：US20130083980A1
公开(公告)日：2013-04-04
申请号：US13551902
申请日：2012-07-18
申请人： Julien Christian Barbot , Atilla Peter Kiraly , Norbert Strobel
发明人： Julien Christian Barbot , Atilla Peter Kiraly , Norbert Strobel
IPC分类号： G06T7/00
CPC分类号： G06T7/0085 , G06T7/0012 , G06T7/13 , G06T7/181 , G06T7/75 , G06T2207/10121 , G06T2207/30021
摘要： A method for the detection of a balloon catheter within a fluoroscopic image, including: removing noise from a fluoroscopic image; detecting edges of a balloon catheter in the fluoroscopic image, wherein the detected edges include subsets of connected edges; extracting an edge subset from the subsets of connected edges; fitting a model to the extracted edge subset; removing outliers of the extracted edge subset based on the fitting of the model; adding the extracted edge subset without the outlier to a data set; repeating the extracting, fitting, removing and adding steps for the remainder of the subsets of connected edges; and fitting the model to the data set, wherein the data set is indicative of the balloon catheter.
摘要翻译：一种用于检测透视图像内的气囊导管的方法，包括：从透视图像中去除噪声; 在透视图像中检测气囊导管的边缘，其中检测到的边缘包括连接边缘的子集; 从连接边缘的子集中提取边缘子集; 将模型拟合到提取的边缘子集; 基于模型的拟合来去除提取的边缘子集的离群值; 将所提取的边缘子集不带异常值添加到数据集; 重复连续边缘子集的其余部分的提取，拟合，移除和添加步骤; 以及将所述模型拟合到所述数据集，其中所述数据集指示所述气囊导管。

8. 发明授权

US08073224B2 System and method for two-dimensional visualization of temporal phenomena and three dimensional vessel reconstruction 有权
标题翻译：用于二维可视化的时间现象和三维血管重建的系统和方法
公开(公告)号：US08073224B2
公开(公告)日：2011-12-06
申请号：US12168199
申请日：2008-07-07
申请人： Norbert Strobel , Liron Yatziv
发明人： Norbert Strobel , Liron Yatziv
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B6/469 , A61B6/481 , G06T7/20 , G06T7/55 , G06T2207/10016 , G06T2207/10116 , G06T2207/30016 , G06T2207/30104
摘要： A method for visualizing temporal phenomena and constructing 3D views from a series of medical images includes providing a first time series of digital images of contrast-enhanced blood flow in a patient, each acquired from a same viewing point with a known epipolar geometry, each said image comprising a plurality of intensities associated with an N-dimensional grid of points, calculating one or more time-density curves from said first time series of digital images, each curve indicative of how the intensity at corresponding points in successive images changes over time, and generating one or more overview images from said time density curves using a color coding technique, wherein said each overview image depict how a physical property value changes from said blood flow at selected corresponding points in said first time series of images.
摘要翻译：一种用于将时间现象可视化并从一系列医学图像构建3D视图的方法包括：在患者中提供对比度增强的血流数字图像的第一时间序列，每个时间序列由具有已知对极几何形状的相同视点获取，图像，包括与N维网格点相关联的多个强度，从所述第一时间序列数字图像计算一个或多个时间密度曲线，每个曲线指示连续图像中相应点处的强度如何随时间变化，以及使用颜色编码技术从所述时间密度曲线生成一个或多个概览图像，其中所述每个概览图像描绘物理属性值如何在所述第一时间序列图像中的选定对应点处从所述血流变化。

9. 发明申请

US20060088140A1 System and method for performing scatter measurement in volumetric CT 审中-公开
标题翻译：在体积CT中进行散射测量的系统和方法
公开(公告)号：US20060088140A1
公开(公告)日：2006-04-27
申请号：US11240233
申请日：2005-09-30
申请人： Rebecca Fahrig , Norbert Strobel , Lei Zhu
发明人： Rebecca Fahrig , Norbert Strobel , Lei Zhu
IPC分类号： G21K1/00
CPC分类号： A61B6/06 , A61B6/583
摘要： The invention provides a system and method for reducing the affects of scattering in an image. The system and method comprises providing at least one blocker array between an x-ray source and an object, obtaining a first image of the via a detector and a first signal, rotationally displacing the at least one blocker array, wherein primary radiation is disrupted at different locations in each projection image, obtaining a second image of the object via the detector and a second signal, estimating the scatter based on a comparison of the first signal and the second signal, and reconstructing a final image by accounting for scatter.
摘要翻译：本发明提供了减少图像中散射影响的系统和方法。该系统和方法包括在x射线源和物体之间提供至少一个阻塞阵列，获得经由检测器的第一图像和第一信号，旋转移位所述至少一个阻断阵列，其中主辐射被破坏在每个投影图像中的不同位置，经由检测器获得对象的第二图像和第二信号，基于第一信号和第二信号的比较来估计散射，以及通过考虑散射来重构最终图像。

10. 发明授权

US08892186B2 Method and system for detection and tracking of coronary sinus catheter electrodes in fluoroscopic images 有权
标题翻译：荧光镜检查和跟踪冠状静脉窦导管电极的方法和系统
公开(公告)号：US08892186B2
公开(公告)日：2014-11-18
申请号：US13229855
申请日：2011-09-12
申请人： Wen Wu , Terrence Chen , Peng Wang , Norbert Strobel , Shaohua Kevin Zhou , Dorin Comaniciu
发明人： Wen Wu , Terrence Chen , Peng Wang , Norbert Strobel , Shaohua Kevin Zhou , Dorin Comaniciu
IPC分类号： A61B5/05 , G06T7/00 , G06T7/20 , A61B19/00
CPC分类号： G06T7/0014 , A61B2034/2065 , A61B2090/376 , G06K2209/057 , G06T7/20 , G06T2207/10121 , G06T2207/30021 , G06T2207/30048
摘要： A method and system for detecting and tracking coronary sinus (CS) catheter electrodes in a fluoroscopic image sequence is disclosed. An electrode model is initialized in a first frame of the fluoroscopic image sequence based on input locations of CS sinus catheter electrodes in the first frame. The electrode model is tracked in subsequent frames of the fluoroscopic image sequence by detecting electrode position candidates in the subsequent frames of the fluoroscopic image sequence using at least one trained electrode detector, generating electrode model candidates in the subsequent frames based on the detected electrode position candidates, calculating a probability score for each of the electrode model candidates, and selecting an electrode model candidate based on the probability score.
摘要翻译：公开了一种用于在荧光镜图像序列中检测和跟踪冠状窦（CS）导管电极的方法和系统。基于第一帧中的CS窦导管电极的输入位置，在荧光镜图像序列的第一帧中初始化电极模型。通过使用至少一个经过训练的电极检测器检测荧光镜像图像序列的后续帧中的电极位置候选物，在荧光图像序列的后续帧中跟踪电极模型，基于检测到的电极位置候选产生后续帧中的电极模型候选计算每个电极模型候选的概率分数，并且基于概率分数来选择电极模型候选。

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