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1. 发明申请

US20060133964A1 Closed loop automated matrix removal 审中-公开
标题翻译：闭环自动矩阵去除
公开(公告)号：US20060133964A1
公开(公告)日：2006-06-22
申请号：US11254030
申请日：2005-10-18
申请人： Thomas Bailey , Michael Ahern , Michael West , Qin Wang , Zhenbiao Wang , James Tappan
发明人： Thomas Bailey , Michael Ahern , Michael West , Qin Wang , Zhenbiao Wang , James Tappan
IPC分类号： G01N33/00
CPC分类号： G01N31/02 , G01N1/34 , G01N1/4077 , H01J49/04 , Y10T436/25375
摘要： An automated matrix removal module is configurable to automatically withdraw a portion of sample containing an interfering matrix. The module is further configurable to mix the portion of sample with a reagent selected to react with the matrix to form a precipitant and then filter the mixture of sample and precipitant reagent through a filter. Finally, the module is further configurable to flush the precipitant from the filter.
摘要翻译：自动矩阵去除模块可配置为自动提取包含干扰矩阵的样本的一部分。该模块进一步可配置以将样品的一部分与选择与基质反应的试剂混合以形成沉淀剂，然后通过过滤器过滤样品和沉淀剂的混合物。最后，该模块进一步可配置以从过滤器冲洗沉淀剂。

2. 发明申请

US20060138321A1 Nebulizer with plasma source 失效
公开(公告)号：US20060138321A1
公开(公告)日：2006-06-29
申请号：US11357240
申请日：2006-02-17
申请人： Michael Ahern , Howard Kingston
发明人： Michael Ahern , Howard Kingston
IPC分类号： H01J49/00
CPC分类号： H01J49/165 , H01J49/105 , H01J49/107
摘要： A combination electrospray/microwave induced plasma (MIP) ionization source is used as the ionization source for a mass spectrometer. The electrospray can be operated in positive mode, negative mode, or it can be switched off. The microwave-induced plasma can also be switched on or off. This allows the instrument to be operated in multiple modes. With the electrospray off and the MIP on, the instrument will normally have its maximum elemental sensitivity. Mixed mode operation potentially allows the determination of additional information about the chemical constituents present in the analyte. In pure electrospray mode, it is possible to obtain molecular information and to analyze organic compounds.

3. 发明授权

US07378652B2 Nebulizer with plasma source 失效
标题翻译：雾化器等离子体源
公开(公告)号：US07378652B2
公开(公告)日：2008-05-27
申请号：US11357240
申请日：2006-02-17
申请人： Michael Ahern , Howard M. Kingston
发明人： Michael Ahern , Howard M. Kingston
IPC分类号： H01J49/10 , H01J49/04
CPC分类号： H01J49/165 , H01J49/105 , H01J49/107
摘要： A combination electrospray/microwave induced plasma (MIP) ionization source is used as the ionization source for a mass spectrometer. The electrospray can be operated in positive mode, negative mode, or it can be switched off. The microwave-induced plasma can also be switched on or off. This allows the instrument to be operated in multiple modes. With the electrospray off and the MIP on, the instrument will normally have its maximum elemental sensitivity. Mixed mode operation potentially allows the determination of additional information about the chemical constituents present in the analyte. In pure electrospray mode, it is possible to obtain molecular information and to analyze organic compounds.
摘要翻译：组合电喷雾/微波诱导等离子体（MIP）电离源被用作质谱仪的电离源。电喷雾可以在正模式，负模式下操作，也可以关闭。微波感应等离子体也可以打开或关闭。这允许仪器在多种模式下操作。当电喷雾和MIP打开时，仪器通常具有最大的元素灵敏度。混合模式操作可能允许确定关于分析物中存在的化学成分的附加信息。在纯电喷雾模式中，可以获得分子信息并分析有机化合物。

4. 发明申请

US20070141720A1 Automated analysis of cations in acidic solutions 审中-公开
标题翻译：酸性溶液中阳离子的自动分析
公开(公告)号：US20070141720A1
公开(公告)日：2007-06-21
申请号：US11305624
申请日：2005-12-16
申请人： Larry Stewart , Jimmy Dzuong , Harmesh Saini , Quoc Truong , Hien Nguyen , Michael Ahern , Bijan Ghaderi
发明人： Larry Stewart , Jimmy Dzuong , Harmesh Saini , Quoc Truong , Hien Nguyen , Michael Ahern , Bijan Ghaderi
IPC分类号： G01N1/18
CPC分类号： B01J49/57 , B01J41/07 , B01J49/07 , G01N30/02 , Y10T436/255 , B01D15/363
摘要： In one embodiment, a matrix elimination apparatus for eliminating an acidic matrix includes: at least one column packed with a weak anion exchange resin; a source of samples, each sample having an acidic matrix; a basic solution source; a weakly acidic metal complexing reagent source, and an at least one pump, wherein the matrix elimination apparatus is configured such that the at least one pump can sequence through the acts of: a) pumping the basic solution through the column to regenerate the column, b) pumping the weakly acid metal complexing reagent through the column to activate the column; and c) pumping one of the samples through the activated column to provide a processed sample whose acidic matrix is eliminated.
摘要翻译：在一个实施方案中，用于消除酸性基质的基质消除装置包括：至少一个填充有弱阴离子交换树脂的柱; 样品来源，每个样品具有酸性基质; 一个基本的解决方案来源; 弱酸性金属络合试剂源和至少一个泵，其中所述基质消除装置被配置为使得所述至少一个泵可以顺序执行以下动作：a）将碱性溶液泵送通过柱以再生塔， b）将弱酸金属络合试剂泵送通过柱来活化柱; 和c）将一个样品泵送通过活化柱以提供其酸性基质被消除的经处理的样品。

5. 发明授权

US07253294B2 Isolation of lutein from alfalfa 失效
标题翻译：从紫花苜蓿中分离叶黄素
公开(公告)号：US07253294B2
公开(公告)日：2007-08-07
申请号：US11463193
申请日：2006-08-08
申请人： Mark Hoffman , David Baugh , Michael Ahern , David Walsh
发明人： Mark Hoffman , David Baugh , Michael Ahern , David Walsh
IPC分类号： C11B1/00
CPC分类号： A61K8/922 , A23K10/37 , A23K20/174 , A23K20/179 , A23L2/06 , A23L2/52 , A23L5/44 , A23L33/105 , A23L33/155 , A23V2002/00 , A61K8/31 , A61K8/345 , A61K8/671 , A61K8/97 , A61K31/015 , A61K31/07 , A61K36/00 , A61K36/21 , A61K36/31 , A61K36/48 , A61K36/61 , A61Q19/00 , C07C403/24 , Y02P60/877 , A61K2300/00 , A23V2250/211
摘要： The present invention provides a process for an industrial scale extraction and purification of xanthophylls (e.g., lutein and zeaxanthin) from plant material (e.g., alfalfa or other leafy green crops having high levels of chlorophyll). The process involves harvesting lutein rich alfalfa, extracting an oleoresin from the alfalfa leaves, saponifying the oleoresin, extracting and extracting lutein using a series of solvent extractions specific for oleoresin obtained from alfalfa or other leafy green plants.
摘要翻译：本发明提供了从植物材料（例如，具有高水平的叶绿素的苜蓿或其他叶绿色作物）的工业规模提取和纯化叶黄素（例如叶黄素和玉米黄质）的方法。该方法包括收获富含叶黄素的苜蓿，从苜蓿叶中提取油树脂，皂化油树脂，使用一系列特异性的从苜蓿或其他绿叶植物获得的油树脂的溶剂萃取提取和提取叶黄素。

6. 发明申请

US20070118538A1 Forms integration of an external data model not implemented through a document object model (DOM) accessible application programming interface (API) 失效
标题翻译：未通过文档对象模型（DOM）访问的应用程序编程接口（API）实现的外部数据模型的表单集成
公开(公告)号：US20070118538A1
公开(公告)日：2007-05-24
申请号：US11282354
申请日：2005-11-18
申请人： Michael Ahern , Derek Carr , Carol Jones , Ajamu Wesley , Cesar Wong
发明人： Michael Ahern , Derek Carr , Carol Jones , Ajamu Wesley , Cesar Wong
IPC分类号： G06F7/00
CPC分类号： G06F17/243
摘要： Embodiments of the present invention address deficiencies of the art in respect to deploying XForms in an enterprise environment and provide a method, system and computer program product for forms integration of an external data model not implemented through a DOM accessible API. In one embodiment of the invention, a method for forms integration of an external data model not implemented through a DOM accessible API can include generating a data graph for an external data model for a forms based application and transforming the data graph into a DOM representation of the data graph. Value changes for fields of a form in the forms based application can be applied to nodes of the DOM representation and mutations in the nodes of the DOM representation can be synchronized to corresponding nodes in the data graph.
摘要翻译：本发明的实施例解决了在企业环境中部署XForm的本领域的缺点，并且提供了用于通过DOM可访问API未实现的外部数据模型的表单集成的方法，系统和计算机程序产品。在本发明的一个实施例中，用于通过DOM可访问API未实现的外部数据模型的形式集成的方法可以包括为基于表单的应用生成用于外部数据模型的数据图，并将数据图转换为数据图。基于表单的应用程序中表单的字段的值更改可以应用于DOM表示的节点，并且DOM表示的节点中的突变可以同步到数据图中的相应节点。

7. 发明授权

US07109361B2 Isolation of lutein from alfalfa 失效
标题翻译：从紫花苜蓿中分离叶黄素
公开(公告)号：US07109361B2
公开(公告)日：2006-09-19
申请号：US10696730
申请日：2003-10-29
申请人： Mark Hoffman , David Baugh , Michael Ahern , David Walsh
发明人： Mark Hoffman , David Baugh , Michael Ahern , David Walsh
IPC分类号： C07C1/00
CPC分类号： A61K8/922 , A23K10/37 , A23K20/174 , A23K20/179 , A23L2/06 , A23L2/52 , A23L5/44 , A23L33/105 , A23L33/155 , A23V2002/00 , A61K8/31 , A61K8/345 , A61K8/671 , A61K8/97 , A61K31/015 , A61K31/07 , A61K36/00 , A61K36/21 , A61K36/31 , A61K36/48 , A61K36/61 , A61Q19/00 , C07C403/24 , Y02P60/877 , A61K2300/00 , A23V2250/211
摘要： The present invention provides a process for an industrial scale extraction and purification of xanthophylls (e.g., lutein and zeaxanthin) from plant material (e.g., alfalfa or other leafy green crops having high levels of chlorophyll). The process involves harvesting lutein rich alfalfa, extracting an oleoresin from the alfalfa leaves, saponifying the oleoresin, extracting and extracting lutein using a series of solvent extractions specific for oleoresin obtained from alfalfa or other leafy green plants.
摘要翻译：本发明提供了从植物材料（例如，具有高水平的叶绿素的苜蓿或其他叶绿色作物）的工业规模提取和纯化叶黄素（例如叶黄素和玉米黄质）的方法。该方法包括收获富含叶黄素的苜蓿，从苜蓿叶中提取油树脂，皂化油树脂，使用一系列特异性的从苜蓿或其他绿叶植物获得的油树脂的溶剂萃取提取和提取叶黄素。

8. 发明申请

US20070098598A1 In-line automated fluid dilution 审中-公开
标题翻译：在线自动化液体稀释
公开(公告)号：US20070098598A1
公开(公告)日：2007-05-03
申请号：US11263155
申请日：2005-10-31
申请人： Michael Ahern , Jimmy Dzuong
发明人： Michael Ahern , Jimmy Dzuong
IPC分类号： B01L3/02
CPC分类号： G01N1/38 , G01N2035/1025 , G01N2035/1032 , G05D11/132
摘要： A system and method for fluid dilution is provided, in one example to be used in conjunction with a chemical analysis tool. In one embodiment, a fluid dilution system includes a supply reservoir including a concentrated fluid, a diluent source including a diluent, and a diluted fluid reservoir operably coupled to the supply reservoir and the diluent source. A fluid level sensor is operably coupled to the diluted fluid reservoir, a pump is operably coupled between the supply reservoir and the diluted fluid reservoir, and a controller is configured to engage the pump based upon signals from the fluid level sensor to pump desired amounts of the concentrated fluid for providing a diluted fluid in the diluted fluid reservoir.
摘要翻译：提供了用于流体稀释的系统和方法，在一个实例中与化学分析工具结合使用。在一个实施例中，流体稀释系统包括供应储存器，其包括浓缩流体，包括稀释剂的稀释剂源和可操作地连接到供应储存器和稀释剂源的稀释流体储存器。流体液位传感器可操作地耦合到稀释的流体储存器，泵可操作地耦合在供应储存器和稀释的流体储存器之间，并且控制器被配置为基于来自流体液位传感器的信号来接合泵，以泵送所需量的用于在稀释的流体储存器中提供稀释的流体的浓缩流体。

9. 发明申请

US20060293543A1 ISOLATION OF LUTEIN FROM ALFALFA 失效
标题翻译：从ALFALFA分离罗丹蛋白
公开(公告)号：US20060293543A1
公开(公告)日：2006-12-28
申请号：US11463193
申请日：2006-08-08
申请人： Mark Hoffman , David Baugh , Michael Ahern , David Walsh
发明人： Mark Hoffman , David Baugh , Michael Ahern , David Walsh
IPC分类号： C07C35/21 , C07C35/06 , C07C13/00
CPC分类号： A61K8/922 , A23K10/37 , A23K20/174 , A23K20/179 , A23L2/06 , A23L2/52 , A23L5/44 , A23L33/105 , A23L33/155 , A23V2002/00 , A61K8/31 , A61K8/345 , A61K8/671 , A61K8/97 , A61K31/015 , A61K31/07 , A61K36/00 , A61K36/21 , A61K36/31 , A61K36/48 , A61K36/61 , A61Q19/00 , C07C403/24 , Y02P60/877 , A61K2300/00 , A23V2250/211
摘要： The present invention provides a process for an industrial scale extraction and purification of xanthophylls (e.g., lutein and zeaxanthin) from plant material (e.g., alfalfa or other leafy green crops having high levels of chlorophyll). The process involves harvesting lutein rich alfalfa, extracting an oleoresin from the alfalfa leaves, saponifying the oleoresin, extracting and extracting lutein using a series of solvent extractions specific for oleoresin obtained from alfalfa or other leafy green plants.
摘要翻译：本发明提供了从植物材料（例如，具有高水平的叶绿素的苜蓿或其他叶绿色作物）的工业规模提取和纯化叶黄素（例如叶黄素和玉米黄质）的方法。该方法包括收获富含叶黄素的苜蓿，从苜蓿叶中提取油树脂，皂化油树脂，使用一系列特异性的从苜蓿或其他绿叶植物获得的油树脂的溶剂萃取提取和提取叶黄素。

10. 发明授权

US07005635B2 Nebulizer with plasma source 失效
标题翻译：雾化器等离子体源
公开(公告)号：US07005635B2
公开(公告)日：2006-02-28
申请号：US10835492
申请日：2004-04-29
申请人： Michael Ahern , Howard M. Kingston
发明人： Michael Ahern , Howard M. Kingston
IPC分类号： H01J49/10 , H01J49/04
CPC分类号： H01J49/165 , H01J49/105 , H01J49/107
摘要： A combination electrospray/microwave induced plasma (MIP) ionization source is used as the ionization source for a mass spectrometer. The electrospray can be operated in positive mode, negative mode, or it can be switched off. The microwave-induced plasma can also be switched on or off. This allows the instrument to be operated in multiple modes. With the electrospray off and the MIP on, the instrument will normally have its maximum elemental sensitivity. Mixed mode operation potentially allows the determination of additional information about the chemical constituents present in the analyte. In pure electrospray mode, it is possible to obtain molecular information and to analyze organic compounds.
摘要翻译：组合电喷雾/微波诱导等离子体（MIP）电离源被用作质谱仪的电离源。电喷雾可以在正模式，负模式下操作，也可以关闭。微波感应等离子体也可以打开或关闭。这允许仪器在多种模式下操作。当电喷雾和MIP打开时，仪器通常具有最大的元素灵敏度。混合模式操作可能允许确定关于分析物中存在的化学成分的附加信息。在纯电喷雾模式中，可以获得分子信息并分析有机化合物。

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