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1. 发明申请

US20130197388A1 DISPOSABLE HAND-HELD DEVICE FOR COLLECTION OF EXHALED BREATH CONDENSATE 审中-公开
标题翻译：用于收集呼吸道呼吸道的可替代的手持装置
公开(公告)号：US20130197388A1
公开(公告)日：2013-08-01
申请号：US13797658
申请日：2013-03-12
申请人： The Charlotte-Mecklenburg Hospital Authority
发明人： Jeffrey A. Kline
IPC分类号： A61B5/097
CPC分类号： A61B5/097 , A61B2010/0087
摘要： A breath condensate collection apparatus comprising a central chamber, a breath input assembly, a plunger assembly and a breath condensate collection port. The central chamber has inner and outer side walls with a coolant material sealed in between. The breath input assembly is disposed on the side of the central chamber in fluid communication with the chamber interior. The plunger assembly has a piston, slidably disposed in the chamber, and a handle extending from a first end of the chamber. The collection port is disposed at the second end of the central chamber in fluid communication with the interior of the chamber. Obstructive structures may be arranged in the chamber interior for increasing the surface area on which condensate may form. The apparatus may also include an outlet assembly that may be removed and replaced with a sampling well into which the condensate may be washed with a buffer solution.
摘要翻译：一种呼吸冷凝物收集装置，包括中央室，呼吸输入组件，柱塞组件和呼吸冷凝物收集口。中央腔室具有密封在其间的冷却剂材料的内侧壁和外侧壁。呼吸输入组件设置在与腔室内部流体连通的中央室侧。柱塞组件具有可滑动地设置在室中的活塞和从腔室的第一端延伸的手柄。采集端口设置在中心室的第二端处，与室的内部流体连通。阻塞结构可以布置在室内，用于增加可形成冷凝物的表面积。该装置还可以包括出口组件，该出口组件可被取出并用采样井替换，冷凝物可用缓冲溶液清洗。

2. 发明申请

US20130190639A1 UTILIZING LIPOPOLYSACCHARIDE IN EXHALED BREATH CONDENSATE TO DIAGNOSE GRAM NEGATIVE PNEUMONIA 审中-公开
标题翻译：在呼吸道呼吸中使用脂多糖
公开(公告)号：US20130190639A1
公开(公告)日：2013-07-25
申请号：US13795370
申请日：2013-03-12
申请人： The Charlotte-Mecklenburg Hospital Authority
发明人： Jeffrey A. Kline , Jackeline Hernandez , John Albert Watts, JR.
IPC分类号： A61B5/08
CPC分类号： A61B5/082 , A61B5/097 , A61B5/412 , C12Q1/04 , C12Q1/14 , G01N33/579 , G01N33/92 , G01N2400/50
摘要： A device for collecting exhaled breath condensate from a subject. The device comprises a plunger assembly and a stopper. The stopper is connected to the plunger disk of the plunger assembly by a plurality of support pins and is configured for sealing engagement. The device is utilized to collect exhaled breath condensate from both spontaneously breathing and mechanically ventilated subjects and the devices utilized to determine whether lipopolysaccharide is present in the collected exhaled breath condensate.
摘要翻译：用于从受试者收集呼出的凝结水的装置。该装置包括柱塞组件和塞子。止动器通过多个支撑销连接到柱塞组件的柱塞盘，并且构造成用于密封接合。该装置用于从自发呼吸和机械通气的受试者收集呼出的呼吸冷凝物，并且用于确定所收集的呼出气体凝结物中是否存在脂多糖的装置。

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