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1. 发明授权

US06175118B1 Gamma camera 失效
标题翻译：伽玛相机
公开(公告)号：US06175118B1
公开(公告)日：2001-01-16
申请号：US09119624
申请日：1998-07-21
申请人： Takuzo Takayama , Takashi Ichihara , Nobutoku Motomura
发明人： Takuzo Takayama , Takashi Ichihara , Nobutoku Motomura
IPC分类号： G01T1161
CPC分类号： G01T1/1647 , A61B6/037 , A61B6/4258 , G01T1/1642
摘要： According to the present invention, sub-windows using a TEW technique are centered to energies corresponding to 1/n and 1/m of maximal photon number in a standard energy spectrum without any scattering component. It is thus possible to improve a count coefficiency, while broadening a main window to a maximal possible extent, without underestimating the scattering component and crosstalk component.
摘要翻译：根据本发明，使用TEW技术的子窗口集中在对应于标准能谱中没有任何散射分量的1 / n和1 / m的最大光子数的能量。因此，可以提高计数系数，同时将主窗口扩大到最大可能程度，而不会低估散射分量和串扰分量。

2. 发明授权

US06281504B1 Diagnostic apparatus for nuclear medicine 失效
标题翻译：核医学诊断仪器
公开(公告)号：US06281504B1
公开(公告)日：2001-08-28
申请号：US09325800
申请日：1999-06-04
申请人： Takuzo Takayama , Takashi Ichihara , Nobutoku Motomura
发明人： Takuzo Takayama , Takashi Ichihara , Nobutoku Motomura
IPC分类号： G01T117
CPC分类号： G01T1/1615 , G01T1/1648
摘要： A diagnostic apparatus for nuclear medicine capable of performing an operation of counting gamma rays for a TCT simultaneously with an operation of counting gamma rays for an SPECT has a SPECT counter for counting, as the number of photons, gamma rays passed through a SPECT energy window centered at a photoelectric peak of the SPECT gamma rays and a TCT counter for counting, as the number of photons, gamma rays passed through a TCT energy window centered at a photoelectric peak of the TCT gamma rays. The number of photons of the gamma rays passed through the SPECT energy window contains the number of photons of K-X rays generated due to a photoelectric effect produced by the TCT gamma rays in collimators of the detector. A K-X ray processor estimates the number of photons of mixed K-X rays on the basis of the number of photons counted at the TCT counter. The K-X ray correction processor performs K-X ray correction on the photon number counted at the SPECT counter on the basis of the photon number of the estimated K-X rays. Since the number of photons passed through the TCT energy window and number of photons of K-X rays passed through the SPECT energy window have a very strong correlation from the standpoint of probability statistics, the accuracy with which the number of photons of the K-X rays passed through the SPECT energy window is estimated is very high. It is, therefore, possible to effectively reduce the K-X rays passed through the SPECT energy window.
摘要翻译：一种用于核医学的诊断装置，其能够对用于SPECT的伽马射线计数的操作同时执行对TCT的伽马射线进行计数的操作，具有SPECT计数器，用于计数通过SPECT能量窗口的γ射线的光子数以SPECT伽马射线的光电峰为中心，以及用于计数的TCT计数器，作为光子的数量，伽马射线通过以TCT伽马射线的光电峰为中心的TCT能量窗。通过SPECT能量窗口的γ射线的光子数目包含由于由检测器的准直仪中的TCT伽马射线产生的光电效应而产生的K-X射线的光子数。基于在TCT计数器上计数的光子数，K-X射线处理器估计混合K-X射线的光子数。基于估计的K-X射线的光子数，K-X射线校正处理器对在SPECT计数器上计数的光子数进行K-X射线校正。由于通过TCT能量窗口的光子数目和通过SPECT能量窗口的KX射线的光子数量从概率统计的观点来看具有非常强的相关性，即KX射线的光子数量通过的准确度 SPECT能量窗估计非常高。因此，有可能有效地减少通过SPECT能量窗口的K-X射线。

3. 发明授权

US5434416A Method and apparatus for reconstructing SPECT image by utilizing two separate reconstruction filter functions 失效
标题翻译：通过利用两个独立的重建滤波器函数来重建SPECT图像的方法和装置
公开(公告)号：US5434416A
公开(公告)日：1995-07-18
申请号：US217102
申请日：1994-03-24
申请人： Nobutoku Motomura , Takashi Ichihara
发明人： Nobutoku Motomura , Takashi Ichihara
IPC分类号： G06T11/00 , A61B6/00 , G01T1/166 , G06F19/00
CPC分类号： G06T11/005 , A61B6/037 , G06T2211/421
摘要： A method and an apparatus for reconstructing SPECT image capable of improving the SPECT image resolution. The apparatus includes: a detector, including a fan-beam collimator, for detecting gamma (.gamma.) rays emitted from a radio isotope injected into a biological body; a rotation unit for effecting relative rotation between the biological body and the detector about a center of rotation to thereby acquire projection data from a different direction; a first reconstructing unit for convoluting the projection data obtained from the detector, by a first convolution function, and for back-projecting the convoluted projection data to a specific region which lies in a sufficiently close vicinity of the detector; a second reconstructing unit for convoluting the projection data by a second convolution function, and for back-projecting the secondly convoluted projection data to another specific region; and display means for displaying thereon a distribution image reconstructed by the first and second reconstructing units.
摘要翻译：一种用于重建能够改善SPECT图像分辨率的SPECT图像的方法和装置。该装置包括：检测器，包括扇形光束准直器，用于检测从注入生物体的放射性同位素发射的伽马射线; 旋转单元，用于围绕旋转中心实现生物体和检测器之间的相对旋转，从而从不同方向获取投影数据; 第一重建单元，用于通过第一卷积函数卷积从所述检测器获得的投影数据，以及将所述卷积投影数据反投影到位于所述检测器的所述特定区域的特定区域; 第二重建单元，用于通过第二卷积函数卷积投影数据，以及用于将第二卷积投影数据反投影到另一特定区域; 以及显示装置，用于在其上显示由第一和第二重建单元重建的分布图像。

4. 发明授权

US5173608A Method for correcting positional shift of gamma camera apparatus and positional shift correcting apparatus thereof 失效
标题翻译：用于校正伽马相机装置及其位置偏移校正装置的位置偏移的方法
公开(公告)号：US5173608A
公开(公告)日：1992-12-22
申请号：US659551
申请日：1991-02-22
申请人： Nobutoku Motomura , Takashi Ichihara
发明人： Nobutoku Motomura , Takashi Ichihara
IPC分类号： G01T1/164
CPC分类号： G01T1/1648 , G01T1/1642 , A61B6/037
摘要： In a gamma camera apparatus, positional shifts contained in an output coordinate matrix of a gamma-ray detector by a method comprising the steps of: positioning a reference RI (radio isotope) source at a first reference position the gamma-ray detector so as to obtain a first positional-information coordinate output from the gamma-ray detector; processing the first positional-information coordinate output indicative of a second reference position with respect to the matrix output derived from the detector so as to produce positional correction data; acquiring a third positional-information coordinate output from the detector while injecting a radio isotope into a biological body under medical examination; and, correcting the third positional-information coordinate output based upon the positional correction data.
摘要翻译：在γ照相机装置中，通过包括以下步骤的方法，包含在γ射线检测器的输出坐标矩阵中的位置偏移：将参考RI（放射性同位素）源定位在第一参考位置处，将伽马射线检测器定位成获得从伽马射线检测器输出的第一位置信息坐标; 处理相对于从检测器导出的矩阵输出指示第二参考位置的第一位置信息坐标输出，以产生位置校正数据; 获取从检测器输出的第三位置信息坐标，同时在体格检查下将放射性同位素注入生物体; 以及基于位置校正数据校正第三位置信息坐标输出。

5. 发明授权

US5739540A Nuclear medicine diagnostic apparatus 失效
标题翻译：核医学诊断仪器
公开(公告)号：US5739540A
公开(公告)日：1998-04-14
申请号：US668230
申请日：1996-06-21
申请人： Nobutoku Motomura , Takashi Ichihara , Hiroharu Kawahara
发明人： Nobutoku Motomura , Takashi Ichihara , Hiroharu Kawahara
IPC分类号： G01T1/161 , A61B6/00 , G01T7/00 , G21K5/00 , G21K5/02
CPC分类号： A61B6/447 , A61B6/037 , G21K5/00
摘要： A nuclear medicine diagnostic apparatus, particularly involving emission computed tomography, wherein absorption correction is performed by a gamma ray source including a plurality of line sources arrayed in a common plane. Each line source produces a radiation distribution having a peak and defining a half-width distance at which the radiation from the line source is attenuated by one-half. The plurality of line sources are arranged at a pitch equal to the half-width distance or an integral multiple of the half-width distance. In one embodiment, a serpentine line source is used having straight line portions and a plurality of bent portions, with the straight line portions arrayed parallel to each other at a pitch equal to the half-width distance or an integral multiple of the half-width distance.
摘要翻译：一种核医学诊断装置，特别涉及发射计算机断层摄影，其中，由包括排列在公共平面中的多个线源的伽马射线源执行吸收校正。每个线源产生具有峰值并限定半线宽度距离的辐射分布，在该距离处来自线源的辐射被衰减一半。多个线源以等于半宽度距离或半角距离的整数倍的间距排列。在一个实施例中，使用具有直线部分和多个弯曲部分的蛇形线源，其中直线部分以等于半宽度距离的间距或半宽度的整数倍彼此平行排列距离。

6. 发明授权

US5371672A Scintillation camera apparatus capable of quantitatively eliminating scattering signal components by setting multiple window and method for quantitatively eliminating scattering signal components 失效
标题翻译：能够通过设定多个窗口定量消除散射信号分量的闪烁照相机装置和定量消除散射信号分量的方法
公开(公告)号：US5371672A
公开(公告)日：1994-12-06
申请号：US841517
申请日：1992-02-26
申请人： Nobutoku Motomura , Takashi Ichihara
发明人： Nobutoku Motomura , Takashi Ichihara
IPC分类号： G01T1/164 , G01T1/208 , G06F15/42
CPC分类号： G01T1/1647 , G01T1/1642 , G01T1/208
摘要： In a scintillation camera apparatus, a gamma-ray scattering signal component is removed from gamma-ray spectral energy distribution data. A scattering component removing method first detects an entire radiation emitted from a radioisotope having a specific energy level and injected into a biological body under medical examination to produce an entire radiation detecting signal. Then only first partial radiation from the radioisotope passing through a first energy range determined in relation to the specific energy level of the radioisotope is detected, thereby producing a first count value of the partial radiation. Partial second and third radiation from the radioisotope passing through second and third energy ranges positioned at both ends of the first energy range and also each having a width narrower than that of the first energy range are then detected, thereby producing second and third count values of the second and third partial radiation. These first to third radiation detecting steps are simultaneously performed. An amount of a scattering radiation component contained in the first partial radiation from the radioisotope passing through the first energy range based on both the second and third count values of the second and third partial radiation is then inferred. The amount of the scattering signal component is then subtracted from the first partial radiation passing through the first energy range, whereby the scattering signal component is removed from the entire radiation detecting signal.
摘要翻译：在闪烁照相机装置中，伽马射线散射信号分量从伽马射线能谱分布数据中去除。散射成分去除方法首先检测从具有比能量水平的放射性同位素发射的整个辐射并在体格检查下注入生物体以产生整个辐射检测信号。然后，仅检测到通过相对于放射性同位素的比能量水平确定的第一能量范围的来自放射性同位素的第一部分辐射，从而产生部分辐射的第一计数值。然后检测来自放射性同位素的部分第二和第三辐射通过位于第一能量范围的两端的第二和第三能量范围，并且每个都具有比第一能量范围窄的宽度，从而产生第二和第三计数值第二和第三部分辐射。这些第一至第三辐射检测步骤同时进行。然后推断出基于第二和第三部分辐射的第二和第三计数值的通过第一能量范围的来自放射性同位素的第一部分辐射中包含的散射辐射成分的量。然后从穿过第一能量范围的第一部分辐射中减去散射信号分量的量，从而从整个辐射检测信号中去除散射信号分量。

7. 发明授权

US06339223B1 Apparatus for truncation correction of transmission CT and nuclear medical diagnostic apparatus using the same 有权
标题翻译：用于传输CT的截断校正的装置和使用其的核医疗诊断装置
公开(公告)号：US06339223B1
公开(公告)日：2002-01-15
申请号：US09348665
申请日：1999-07-06
申请人： Nobutoku Motomura , Takashi Ichihara
发明人： Nobutoku Motomura , Takashi Ichihara
IPC分类号： A61B500
CPC分类号： G06T11/005 , A61B6/5235 , G06T2211/432
摘要： SPECT data is collected to produce a SPECT image and transmission CT projection data is collected to produce a transmission CT image. The contours of the body of a subject under examination is extracted from the SPECT image. Using data representing the contours of the body, a portion of the transmission CT projection data is approximated by a curve. The sum of the curve-approximated transmission CT projection data and the center of gravity of the transmission CT image are computed. The truncated portion is estimated from the sum of the transmission CT projection data and the center of gravity of the transmission CT image and the transmission CT projection data is then corrected. The correction of the transmission CT projection data involves producing (extrapolation) anew a curve represented by a quadratic polynomial for that region (truncated region) of the transmission CT projection data which has been approximated tentatively by an ellipse in order to determine the sum and the center of gravity.
摘要翻译：收集SPECT数据以产生SPECT图像，并且收集透射CT投影数据以产生透射CT图像。从SPECT图像中提取被检查对象的身体轮廓。使用表示身体轮廓的数据，传输CT投影数据的一部分由曲线近似。计算曲线近似透射CT投影数据和透射CT图像的重心之和。根据透射CT投影数据和透射CT图像的重心的和来估计截断部分，然后校正透射CT投影数据。透射CT投影数据的校正包括产生（外插）新曲线由用于确定总和和重心的椭圆近似的透射CT投影数据的该区域（截断区域）的二次多项式表示。

8. 发明授权

US5610402A Scintillation camera 失效
标题翻译：闪烁相机
公开(公告)号：US5610402A
公开(公告)日：1997-03-11
申请号：US412016
申请日：1995-03-28
申请人： Nobutoku Motomura , Takashi Ichihara
发明人： Nobutoku Motomura , Takashi Ichihara
IPC分类号： G01T1/164
CPC分类号： G01T1/1642
摘要： First RI having a first photo-peak and a second photo-peak and second RI having a third photo-peak close to the second photo-peak are simultaneously dosed to a test body. A first injection number is the number of energy injections in the vicinity of the first photo-peak from first RI. A second injection number is obtained as a sum of the third injection number in the vicinity of the second photo-peak from the first RI, and the fourth injection number of energy injections in the vicinity of the third photo-peak from the second RI. The third injection number is obtained on the basis of a predetermined coefficient and the first injection number. Therefore, the injection number of all .gamma. rays emitted from the first RI is obtained on the basis of the third injection number and the first injection number. In addition, all the .gamma. rays emitted from the second RI can be obtained on the basis of the third injection number and the second injection number. The problem of cross-talk can be solved thereby.
摘要翻译：同时将具有第一光峰和第二光峰的第一RI和具有接近第二光峰的第三光峰的第二RI分配给测试体。第一注射次数是从第一次RI开始的第一个光峰附近的能量注入次数。获得第二喷射数作为从第一RI开始的第二光峰附近的第三喷射数与从第二RI相邻的第三光峰附近的第四喷射次数。基于预定系数和第一喷射数量获得第三喷射数。因此，基于第三喷射次数和第一喷射次数获得从第一RI发射的所有γ射线的喷射次数。此外，可以基于第三喷射次数和第二喷射次数获得从第二RI发射的所有γ射线。可以解决串扰问题。

9. 发明授权

US09795352B2 Image processing apparatus and X-ray diagnostic apparatus 有权
公开(公告)号：US09795352B2
公开(公告)日：2017-10-24
申请号：US12688255
申请日：2010-01-15
申请人： Takuya Sakaguchi , Takashi Ichihara , Masanori Matsumoto
发明人： Takuya Sakaguchi , Takashi Ichihara , Masanori Matsumoto
IPC分类号： G06T7/00 , A61B6/00
CPC分类号： A61B6/504 , A61B6/4441 , A61B6/481 , A61B6/507
摘要： An image processing apparatus includes a storage unit which stores data of X-ray projection images generated through a angiographic imaging sequence, a generation unit which, based on the data, generates a reference time density curve concerning a reference region which is set as a blood supply region, and time density curves concerning perfusion regions which are set as a blood supplied region, a measurement unit which measures delay times for which a contrast medium reaches the perfusion regions from the reference region, from relationships between the reference time density curve and the time density curves, a calculation unit which calculates, respectively for the perfusion regions, first indices expressing correlations of the time density curves to the reference time density curve within a period determined on the basis of the delay times, and a first image generation unit which generates a first image expressing spatial distribution of the first indices.

10. 发明授权

US08236591B2 Semiconductor light emitting element and method for manufacturing the same 有权
标题翻译：半导体发光元件及其制造方法
公开(公告)号：US08236591B2
公开(公告)日：2012-08-07
申请号：US12670631
申请日：2008-07-31
申请人： Takashi Ichihara , Hirofumi Yoshida , Takao Yamada , Yohei Wakai
发明人： Takashi Ichihara , Hirofumi Yoshida , Takao Yamada , Yohei Wakai
IPC分类号： H01L29/06 , H01L29/08
CPC分类号： H01S5/0201 , B82Y20/00 , H01L33/0095 , H01S5/0202 , H01S5/0213 , H01S5/305 , H01S5/3063 , H01S5/3202 , H01S5/3211 , H01S5/34333
摘要： A method for manufacturing a semiconductor light emitting element from a wafer in which a gallium nitride compound semiconductor has been laminated on a sapphire substrate having an orientation flat, comprises of: laminating a semiconductor layer on a first main face of the sapphire substrate having an off angle θ in a direction Xo parallel to the orientation flat; forming a first break groove that extends in a direction Y substantially perpendicular to the direction Xo, on the semiconductor layer side; forming a second break line that is shifted by a predetermined distance in the ±Xo direction from a predicted split line within the first break groove and parallel to the first break groove in the interior of the sapphire substrate and corresponding to the inclination of the off angle θ; and splitting the wafer along the first and/or second break line.
摘要翻译：一种半导体发光元件的制造方法，其特征在于，在具有取向平坦化的蓝宝石基板上层叠有氮化镓系化合物半导体的晶片的半导体发光元件的制造方法包括：在具有断开状态的蓝宝石基板的第一主面上层叠半导体层角度和角度在方向Xo平行于取向平面; 形成在所述半导体层侧沿着与所述方向Xo大致垂直的方向Y延伸的第一断裂槽; 形成从第一断裂槽内的预测分割线向±Xo方向偏移预定距离并平行于蓝宝石基板内部的第一断裂槽并对应于偏角的倾斜的第二断裂线＆thetas ;; 以及沿着第一和/或第二断裂线分裂晶片。

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