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1. 发明申请

US20060056831A1 Digital camera 审中-公开
标题翻译：数码相机
公开(公告)号：US20060056831A1
公开(公告)日：2006-03-16
申请号：US11223428
申请日：2005-09-09
申请人： Takeshi Horio , Hiroshi Ueda , Kimihiko Nakamura , Junji Takahata , Akio Kimba , Masayuki Miyazawa
发明人： Takeshi Horio , Hiroshi Ueda , Kimihiko Nakamura , Junji Takahata , Akio Kimba , Masayuki Miyazawa
IPC分类号： G03B17/00
CPC分类号： H04N5/23287 , H04N5/23209 , H04N5/23248
摘要： A digital camera body to which a lens unit having an image taking optical system is attachable. The camera body has a shake detector detecting a camera shake on the digital camera and outputting a shake detection signal, a blur compensator compensates for a blur, due to the camera shake, of a subject light image projected onto an image capturing surface of an image sensor provided in the camera body, based on an inputted blur compensation amount, a focal length deriver obtaining an overall focal length of the image taking optical system, by use of the information on the focal length obtained from the lens unit, and a blur compensation controller deriving the blur compensation amount for compensating for the blur based on the overall focal length of the image taking optical system and the shake detection signal, and outputting the blur compensation amount to the blur compensator.
摘要翻译：具有摄像光学系统的透镜单元可附接到其上的数码相机机身。相机主体具有检测数码相机上的相机震动的抖动检测器，并且输出抖动检测信号，模糊补偿器补偿投影到图像的图像捕获表面上的被摄体光图像的由于相机抖动引起的模糊基于输入的模糊补偿量设置在相机机体中的传感器，通过使用从透镜单元获得的焦距的信息获得获取摄像光学系统的整体焦距的焦距提升器和模糊补偿控制器基于摄像光学系统的整体焦距和抖动检测信号导出用于补偿模糊的模糊补偿量，并将模糊补偿量输出到模糊补偿器。

2. 发明授权

US06528778B1 Optical sensor and optical unit 有权
标题翻译：光学传感器和光学单元
公开(公告)号：US06528778B1
公开(公告)日：2003-03-04
申请号：US09327423
申请日：1999-06-08
申请人： Akio Kimba , Hiroshi Ueda , Iwao Ishida
发明人： Akio Kimba , Hiroshi Ueda , Iwao Ishida
IPC分类号： H01L3100
CPC分类号： H01L27/14618 , H01L27/14625 , H01L2924/0002 , H04N5/2253 , H01L2924/00
摘要： In an optical unit such as AF sensor used in a camera, a sensor module is directly fixed on a flexible printed circuit substrate in a manner so that an array of photo-sensing devices formed on the sensor chip is directly connected to conductive patterns on the flexible printed circuit substrate. The printed circuit substrate with the sensor module is held by a sensor holder, and the sensor holder is fixed on an exit opening of a base member of the optical unit in a manner so that the photo-sensing surface of the sensor chip is perpendicular to an optical axis of optical elements such as lenses held on the base member.
摘要翻译：在诸如在相机中使用的AF传感器的光学单元中，传感器模块以这样的方式直接固定在柔性印刷电路基板上，使得形成在传感器芯片上的光敏元件的阵列直接连接到传感器芯片上的导电图案柔性印刷电路基板。具有传感器模块的印刷电路基板由传感器保持器保持，传感器保持器固定在光学单元的基底部件的出口上，使得传感器芯片的光敏表面垂直于诸如保持在基底构件上的透镜的光学元件的光轴。

3. 发明授权

US06346694B1 Focus detecting device and a method for the focus detection 有权
标题翻译：焦点检测装置和焦点检测方法
公开(公告)号：US06346694B1
公开(公告)日：2002-02-12
申请号：US09327515
申请日：1999-06-08
申请人： Akio Kimba , Hiroshi Ueda , Masataka Hamada
发明人： Akio Kimba , Hiroshi Ueda , Masataka Hamada
IPC分类号： G02B709
CPC分类号： G02B7/34 , G03B13/36
摘要： A focus detecting device comprising a taking lens for photographing an object, a relay optical system for re-forming an object image via the taking lens, and a detecting means having first and second sensor pairs for detecting the image re-formed by the relay optical system, wherein focus detection is accomplished using one sensor of the first sensor pair and one sensor of the second sensor pair.
摘要翻译：一种聚焦检测装置，包括用于拍摄物体的拍摄镜头，用于经由拍摄镜头重新形成物体图像的中继光学系统，以及具有用于检测由中继光学器件重新形成的图像的第一和第二传感器对的检测装置系统，其中使用第一传感器对的一个传感器和第二传感器对的一个传感器来实现焦点检测。

4. 发明授权

US6108495A Camera 有权
标题翻译：相机
公开(公告)号：US6108495A
公开(公告)日：2000-08-22
申请号：US299924
申请日：1999-04-28
申请人： Junji Takahata , Hiroshi Ueda , Hironori Kamishita , Koutaro Kawabe
发明人： Junji Takahata , Hiroshi Ueda , Hironori Kamishita , Koutaro Kawabe
IPC分类号： G03B13/36 , G02B7/28 , G02B7/32 , G03B13/18
CPC分类号： G02B7/32
摘要： In addition to a focus detecting sensor for phase difference detection, a camera is provided with a light source or a generator for emitting light or ultrasonic waves, and a light receiver or a receiver for receiving the light or the ultrasonic waves reflected from the object. The distance to the object is detected from the intensity of the reflected light or ultrasonic waves and the focusing lens is set at a position close to the in-focus position. Then, the driving range of the focusing lens is limited in accordance with the detected distance, and from the set focusing lens position, focusing by the phase difference detection method is performed within the limited driving range.
摘要翻译：除了用于相位差检测的焦点检测传感器之外，相机设置有用于发射光或超声波的光源或发生器，以及用于接收从物体反射的光或超声波的光接收器或接收器。从反射光或超声波的强度检测到物体的距离，并且将聚焦透镜设置在靠近对焦位置的位置。然后，根据检测到的距离来限制聚焦透镜的驱动范围，并且从设定的聚焦透镜位置，在有限的驱动范围内执行通过相位差检测方法的聚焦。

5. 发明授权

US5765055A Lens-exchangeable camera 失效
标题翻译：镜头可更换相机
公开(公告)号：US5765055A
公开(公告)日：1998-06-09
申请号：US790942
申请日：1997-01-29
申请人： Masayuki Miyazawa , Hiroshi Ueda
发明人： Masayuki Miyazawa , Hiroshi Ueda
IPC分类号： G03B7/20 , G02B7/02 , G02B7/28 , G02B7/32 , G03B7/28 , G03B17/14 , G03B3/00
CPC分类号： G03B17/14
摘要： In a program reset processing, a camera confirms stopping of the lens by a focus lens drive state obtaining communication. Then, a lens request obtaining communication is performed. When the lens can return to the AF mode and is in the MF mode, an "AF/MF switch instruction" is transmitted. When a "lens request obtain" communication is performed and it is confirmed that the mode has been switched to the AF mode, "mechanism resetting" is performed. Thus, troubles in setting the focus mode can be prevented.
摘要翻译：在程序复位处理中，相机通过获得通信的聚焦透镜驱动状态来确认透镜的停止。然后，执行透镜请求获取通信。当镜头可以返回到AF模式并处于MF模式时，传送“AF / MF切换指令”。当执行“镜头请求获取”通信并且确认该模式已被切换到AF模式时，执行“机构复位”。因此，可以防止设置聚焦模式的麻烦。

6. 发明授权

US5748999A Lens-exchangeable camera 失效
标题翻译：镜头可更换相机
公开(公告)号：US5748999A
公开(公告)日：1998-05-05
申请号：US791697
申请日：1997-01-30
申请人： Hiroshi Ueda , Masayuki Miyazawa
发明人： Hiroshi Ueda , Masayuki Miyazawa
IPC分类号： G03B7/20 , G02B7/02 , G02B7/28 , G02B7/32 , G03B7/28 , G03B17/14 , G03B13/36
CPC分类号： G03B17/14
摘要： In performing an AF operation in a lens-exchangeable camera, whether or not the DVP reference for a lens mounted (i.e., a position serving as a reference for forward movement of the lens) is infinity, is determined. When the DVP reference is infinite, an AF operation is performed with a decision on subject movement. If the DVP reference is not infinity, an AF operation is performed without a decision on subject movement. Thus, a lens-exchangeable camera can be provided capable of preventing malfunction due to an inappropriate reference position for forward movement of the lens.
摘要翻译：在可透镜相机中执行AF操作时，确定安装的镜头的DVP参考（即，用作镜头的向前移动的基准的位置）是否为无穷大。当DVP参考值无限大时，可以对被摄体移动进行决定，进行AF操作。如果DVP参考值不是无穷远，则在不对被摄体移动进行决定的情况下执行AF操作。因此，可以提供能够防止由于用于镜头向前移动的不适当基准位置而导致的故障的镜头可更换照相机。

7. 发明授权

US09023835B2 Agent for ameliorating blood-brain barrier disorders 有权
标题翻译：改善血脑屏障障碍的药剂
公开(公告)号：US09023835B2
公开(公告)日：2015-05-05
申请号：US13390058
申请日：2010-08-09
申请人： Hiroshi Ueda
发明人： Hiroshi Ueda
IPC分类号： A61K38/22 , A61K45/06
CPC分类号： A61K38/2292 , A61K45/06 , A61K2300/00
摘要： The invention provides a method of ameliorating a blood-brain barrier disorder, as well as a method of treating a disease accompanied by a blood-brain barrier disorder and a method of treating a cerebral ischemic disease, by administering a prothymosin α, or a protein or polypeptide possessing the same function as the prothymosin α. The invention also provides polypeptides useful in the context of the aforesaid methods.
摘要翻译：本发明提供一种改善血脑屏障障碍的方法，以及治疗伴有血脑屏障障碍的疾病的方法和治疗脑缺血疾病的方法，通过施用孕激素α或蛋白质或具有与胸腺素α相同功能的多肽。本发明还提供了在上述方法的上下文中有用的多肽。

8. 发明申请

US20130203738A1 USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) 有权
标题翻译：使用化合物结合到MSIN3B，特异性结合到神经元限制性沉默因子（NRSF）
公开(公告)号：US20130203738A1
公开(公告)日：2013-08-08
申请号：US13578230
申请日：2011-02-09
申请人： Yoshifumi Nishimura , Aritaka Nagadoi , Yuuka Hirao , Yoshio Goshima , Naoya Yamashita , Naoki Miyata , Takayoshi Suzuki , Ryuta Hiraishi , Hiroshi Ueda
发明人： Yoshifumi Nishimura , Aritaka Nagadoi , Yuuka Hirao , Yoshio Goshima , Naoya Yamashita , Naoki Miyata , Takayoshi Suzuki , Ryuta Hiraishi , Hiroshi Ueda
IPC分类号： C07D211/16 , C07D211/10 , C07D265/30 , C07D207/06 , C07D223/04 , C07D225/02 , C07D211/14 , C07C233/65
CPC分类号： C07D211/16 , A61K31/445 , C07C233/65 , C07C233/66 , C07C2601/14 , C07D207/06 , C07D211/10 , C07D211/14 , C07D211/96 , C07D223/04 , C07D225/02 , C07D265/30 , C07D295/192
摘要： The present invention identifies a compound which binds to the PAH1 domain of mSin3B that specifically binds to neural restrictive silencer factor NRSF, and uses the compound as a prophylactic and/or a therapeutic for diseases associated with abnormal expression of neural restrictive silencer factor NRSF/REST or abnormal expression of genes targeted by NRSF/REST, such as Huntington's disease, medulloblastoma and neuropathic pain.The present invention provides a pharmaceutical composition comprising a substance capable of binding to the PAH1 domain of mSin3B, e.g., a compound represented by the following formula (I), a pharmacologically acceptable salt thereof, or a pharmacologically acceptable ester thereof: wherein n represents 0 or 1; R1, R2, R3, R4 and R5 each independently represent a hydrogen atom, a hydrocarbon group or a functional group; Y represents a single bond, a carbonyl group, —CONH—, —NHCO— or a sulfonyl group; and Z represents a nitrogen-containing heterocyclic group which may have a substituent, an amino group which may have a hydrocarbon group or an aromatic hydrocarbon group, or a nitrogen and oxygen-containing heterocyclic group which may have a substituent.
摘要翻译：本发明鉴定了与特异性结合神经限制性沉默因子NRSF的mSin3B的PAH1结构域结合的化合物，并且将该化合物用作与神经限制性消音因子NRSF / REST的异常表达相关的疾病的预防和/或治疗或NRSF / REST靶向的基因异常表达，如亨廷顿氏病，成神经管细胞瘤和神经性疼痛。本发明提供一种药物组合物，其包含能够结合mSin3B的PAH1结构域的物质，例如下式（I）表示的化合物，其药理学上可接受的盐或其药理学上可接受的酯：其中n表示0 或1; R1，R2，R3，R4和R5各自独立地表示氢原子，烃基或官能团; Y表示单键，羰基，-CONH-，-NHCO-或磺酰基; Z表示可以具有取代基的含氮杂环基，可以具有烃基或芳香族烃基的氨基或可以具有取代基的含氮和含氧杂环基。

9. 发明授权

US08411196B2 Digital camera with movable mirror for AF in live view mode and optical viewfinder mode 有权
标题翻译：带实时取景模式和光学取景器模式的AF的可移动镜头的数码相机
公开(公告)号：US08411196B2
公开(公告)日：2013-04-02
申请号：US12095818
申请日：2006-11-30
申请人： Hiroshi Ueda , Kenichi Honjo , Naoto Yumiki , Toshio Makabe , Kenji Maeda , Kaoru Mokunaka , Kazuhiko Ishimaru
发明人： Hiroshi Ueda , Kenichi Honjo , Naoto Yumiki , Toshio Makabe , Kenji Maeda , Kaoru Mokunaka , Kazuhiko Ishimaru
IPC分类号： H04N5/232
CPC分类号： H04N5/23203 , G03B19/00 , G03B19/12 , H04N5/2254 , H04N5/23212 , H04N5/23245 , H04N5/23293 , H04N5/238
摘要： A digital camera of the present invention includes a microcomputer 110 having a live view mode controlling so that image data generated by a CMOS sensor 130 or image data obtained by subjecting the image data generated by the CMOS sensor 130 to predetermined processing is displayed on a liquid crystal monitor 150 as a moving image in real time, wherein when a release button 141 receives an instruction regarding start of an autofocus operation in a live view mode, the microcomputer 110 controls a movable mirror to enter an optical path to measure by an AF sensor 132, and thereafter, allow the movable mirror to retract from the optical path to return the digital camera to the live view mode. Due to this configuration, in a digital camera that includes a movable mirror and is capable of displaying a subject image in a live view through an electronic viewfinder, the operability thereof can be enhanced.
摘要翻译：本发明的数码相机包括具有实时取景模式控制的微型计算机110，使得由CMOS传感器130生成的图像数据或通过对由CMOS传感器130生成的图像数据进行预定处理而获得的图像数据显示在液体晶体监视器150作为运动图像实时地实现，其中当释放按钮141接收到关于在实时取景模式中的自动对焦操作的开始的指令时，微型计算机110控制可移动反射镜进入光学路径以由AF传感器 132，然后允许可移动镜从光路缩回以将数字照相机返回到实时取景模式。由于这种结构，在包括可移动镜并且能够通过电子取景器在实时取景中显示被摄体图像的数码相机中，可以提高其可操作性。

10. 发明申请

US20120270338A1 FLUOROIMMUNOASSAY METHOD 审中-公开
标题翻译：荧光分光法
公开(公告)号：US20120270338A1
公开(公告)日：2012-10-25
申请号：US13510105
申请日：2010-11-19
申请人： Hiroshi Ueda , Ryoji Abe , Masaki Ihara , Hiroaki Takagi
发明人： Hiroshi Ueda , Ryoji Abe , Masaki Ihara , Hiroaki Takagi
IPC分类号： G01N21/76 , C07K17/02
CPC分类号： G01N33/582 , A61K49/0058 , C07K16/18 , C07K16/44 , C07K2317/56 , C07K2317/622 , C07K2317/92 , G01N21/6428 , G01N33/6857 , G01N2021/6439
摘要： An object is to provide an immunoassay method requiring neither a solid-phase immobilization step nor a washing step, enabling quick and simple quantitative measurement of a target substance in a liquid phase and capable of visualizing an antigen. Such an object is attained by measuring the concentration of a target antigen present in a test substance by sequentially performing a step (a) of bringing an antibody light-chain variable region polypeptide and an antibody heavy-chain variable region polypeptide labeled with a fluorescent dye into contact with an antigen in a test substance in a liquid phase; or bringing an antibody heavy-chain variable region polypeptide and an antibody light-chain variable region polypeptide labeled with a fluorescent dye into contact with an antigen in a test substance in a liquid phase; a step (b) of measuring the fluorescence intensity of the fluorescent dye; and a step (c) of computationally obtaining the level of the antigen contained in the test substance with reference to a positive correlation between the concentration of the antigen in a liquid phase and the fluorescence intensity of the fluorescent dye.
摘要翻译：本发明的目的是提供一种不需要固相固定步骤和洗涤步骤的免疫测定方法，能够快速和简单地定量测定液相中的目标物质并能够使抗原呈现。通过依次进行使荧光染料标记的抗体轻链可变区多肽和抗体重链可变区多肽的步骤（a），测定待测物质中存在的靶抗原的浓度，与液相中测试物质中的抗原接触; 或使用荧光染料标记的抗体重链可变区多肽和抗体轻链可变区多肽与液相中的测试物质中的抗原接触; 测量荧光染料的荧光强度的步骤（b）; 和（c）参考在液相中的抗原浓度与荧光染料的荧光强度之间的正相关性来计算获得测试物质中含有的抗原水平的步骤（c）。

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