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    • 1. 发明授权
    • Highly concentrated aqueous solutions of N,N-dialkyl-glycines and process for preparation thereof
    • N,N-二烷基甘氨酸的高浓度水溶液及其制备方法
    • US07056450B2
    • 2006-06-06
    • US10491717
    • 2002-10-03
    • Takashi UedaMakoto SaitoTohru KatohKatsuhisa Inoue
    • Takashi UedaMakoto SaitoTohru KatohKatsuhisa Inoue
    • C07C229/12C07C227/42C09K3/00
    • C07C227/18C07C229/12
    • An aqueous high-concentration solution of N,N-dialkylglycine, economical, easy to handle, and useful for subsequent organic chemical reactions, is provided. Also is provided a process for production thereof. The aqueous high-concentration solution of N,N-dialkylglycine which contains the N,N-dialkylglycine at a concentration of 30–80% by mass, and a metal-mineral acid salt at a content of 0.3–3% by mass can be produced industrially from an aqueous N,N-dialkylglycine alkali metal salt as the source material by the steps of (i) neutralizing an aqueous solution of an N,N-dialkylglycine alkali metal salt with a mineral acid, (ii) condensing the obtained aqueous solution by removal of water, and (iii) separating by solid-liquid separation the deposited alkali metal-mineral acid salt from the resulting slurry of the aqueous N,N-dialkylglycine solution and the alkali metal-mineral acid salt.
    • 提供了经济,易于处理并且用于随后的有机化学反应的N,N-二烷基甘氨酸的高浓度水溶液。 还提供了其生产方法。 含有浓度为30〜80质量%的N,N-二烷基甘氨酸的N,N-二烷基甘氨酸的水溶液高浓度溶液和0.3〜3质量%的金属 - 无机酸盐可以是 以(i)用无机酸中和N,N-二烷基甘氨酸碱金属盐的水溶液,(ii)将得到的水溶液(N,N-二烷基甘氨酸碱金属盐)中和,得到工业上由N,N-二烷基甘氨酸碱金属盐水溶液作为原料, 通过去除水分解溶液,和(iii)通过固液分离沉淀的碱金属 - 无机酸盐从N,N-二烷基甘氨酸水溶液和碱金属 - 无机酸盐的所得浆液中分离。
    • 2. 发明申请
    • Hair cosmetic, aminocarboxylic acid amide and method for producing the same
    • 毛发化妆品,氨基羧酸酰胺及其制造方法
    • US20050037934A1
    • 2005-02-17
    • US10948656
    • 2004-09-24
    • Katsuhisa InoueTakeshi KaharuTohru Katoh
    • Katsuhisa InoueTakeshi KaharuTohru Katoh
    • C07C237/08C07D295/15A61K7/075
    • C07D295/15A61K8/42A61Q5/006A61Q5/02A61Q5/06A61Q5/12C07C237/08
    • A hair cosmetic which can impart, to hairs, flexibility, smoothness and oily feeling when the hairs are wetted and smoothness, softness and combing easiness after the hairs are dried are provided, the hair cosmetic comprising an amine represented by the formula (I): (wherein R1 represents a C8-40 alkyl group or alkenyl group or a group represented by the formula R5O-(AO)n—CmH2m—(R5 represents a C8-40 alkyl group or alkenyl group having 8 to 40 carbon atoms, A represents a C2-3 alkylene group, n denotes a number from 0 to 30 in average and m denotes an integer of 2 or 3), R represents a C1-5 alkylene group, R represents H, a C1-24 alkyl group, alkenyl group or hydroxyalkyl group or a C6-28 aryl group or arylalkyl group, R4 represents H, a C1-5 alkyl group, alkylene group or hydroxyalkyl group or a C6-28 aryl group or arylalkyl group, p denotes an integer from 1 to 3, q and r denote integers from 0 to 2 and p+q+r is equal to 3. Also, the amine (I) can be produced with high selectivity and highly economically by reacting a primary amine with an aminocarboxylic acid to run amidation. An amine represented by the formula (1), its salt or quaternary ammonium salt are also provided:
    • 本发明提供一种毛发化妆品,其含有由式(I)表示的胺类的毛发化妆品,其能够赋予毛发润湿后的毛发,柔软性,平滑性,油性感,柔软性,梳理容易性。 (其中R 1表示C8-40烷基或烯基或由式R 5表示的基团O-(AO)n -C m H 2m - (R 5)表示C8-40烷基或烯基 具有8〜40个碳原子的基团,A表示C2-3亚烷基,n表示平均为0〜30的数,m表示2或3的整数),R表示C 1-5亚烷基,R表示H ,C 1-4烷基,烯基或羟烷基或C 6-28芳基或芳烷基,R 4表示H,C 1-5烷基,亚烷基或羟烷基或C 6-28芳基 或芳烷基,p表示1至3的整数,q和r表示0至2的整数,p + q + r等于3.此外,胺(I)可以以高选择性 并且通过使伯胺与氨基羧酸反应以进行酰胺化而高度经济地进行。 还提供了由式(1)表示的胺,其盐或季铵盐:
    • 3. 发明授权
    • Hair cosmetic, aminocarboxylic acid amide and method for producing the same
    • 毛发化妆品,氨基羧酸酰胺及其制造方法
    • US07524486B2
    • 2009-04-28
    • US10948656
    • 2004-09-24
    • Katsuhisa InoueTakeshi KaharuTohru Katoh
    • Katsuhisa InoueTakeshi KaharuTohru Katoh
    • A61K8/41
    • C07D295/15A61K8/42A61Q5/006A61Q5/02A61Q5/06A61Q5/12C07C237/08
    • A hair cosmetic which can impart, to hairs, flexibility, smoothness and oily feeling when the hairs are wetted and smoothness, softness and combing easiness after the hairs are dried are provided, the hair cosmetic comprising an amine represented by the formula (I): (wherein R1 represents a C8-40 alkyl group or alkenyl group or a group represented by the formula R5O-(AO)n—CmH2m—(R5 represents a C8-40 alkyl group or alkenyl group having 8 to 40 carbon atoms, A represents a C2-3 alkylene group, n denotes a number from 0 to 30 in average and m denotes an integer of 2 or 3), R2 represents a C1-5 alkylene group, R3 represents H, a C1-24 alkyl group, alkenyl group or hydroxyalkyl group or a C6-28 aryl group or arylalkyl group, R4 represents H, a C1-5 alkyl group, alkylene group or hydroxyalkyl group or a C6-28 aryl group or arylalkyl group, p denotes an integer from 1 to 3, q and r denote integers from 0 to 2 and p+q+r is equal to 3. Also, the amine (I) can be produced with high selectivity and highly economically by reacting a primary amine with an aminocarboxylic acid to run amidation. An amine represented by the formula (1), its salt or quaternary ammonium salt are also provided:
    • 本发明提供一种毛发化妆品,其含有由式(I)表示的胺类的毛发化妆品,其能够赋予毛发润湿后的毛发,柔软性,平滑性,油性感,柔软性,梳理容易性。 (其中R1表示C8-40烷基或烯基或由式R5O-(AO)n-CmH2m-表示的基团,(R5表示碳原子数为8〜40的C8-40烷基或烯基,A表示 C2-3亚烷基,n表示平均为0〜30的数,m表示2或3的整数),R2表示C1-5亚烷基,R3表示H,C1〜24的烷基,烯基 或羟烷基或C 6-28芳基或芳烷基,R 4表示H,C 1-5烷基,亚烷基或羟烷基或C 6-28芳基或芳烷基,p表示1〜3的整数, q和r表示0至2的整数,p + q + r等于3.此外,可以以高选择性制备胺(I) 并且通过使伯胺与氨基羧酸反应以进行酰胺化而非常经济地进行。 还提供了由式(1)表示的胺,其盐或季铵盐:
    • 4. 发明授权
    • Hair cosmetic, aminocarboxylic acid amide and method for producing the same
    • 毛发化妆品,氨基羧酸酰胺及其制造方法
    • US07531165B2
    • 2009-05-12
    • US10997945
    • 2004-11-29
    • Katsuhisa InoueTakeshi KaharuTohru Katoh
    • Katsuhisa InoueTakeshi KaharuTohru Katoh
    • A61K8/41
    • C07D295/15A61K8/42A61Q5/006A61Q5/02A61Q5/06A61Q5/12C07C237/08
    • A hair cosmetic which can impart, to hairs, flexibility, smoothness and oily feeling when the hairs are wetted and smoothness, softness and combing easiness after the hairs are dried are provided, the hair cosmetic comprising an amine represented by the formula (I):Formula (I) (wherein R1 represents a C8-40 alkyl group or alkenyl group or a group represented by the formula R5O-(AO)n—CmH2m—(R5 represents a C8-40 alkyl group or alkenyl group having 8 to 40 carbon atoms, A represents a C2-3 alkylene group, n denotes a number from 0 to 30 in average and m denotes an integer of 2 or 3), R2 represents a C1-5 alkylene group, R3 represents H, a C1-24 alkyl group, alkenyl group or hydroxyalkyl group or a C6-28 aryl group or arylalkyl group, R4 represents H, a C1-5 alkyl group, alkylene group or hydroxyalkyl group or a C6-28 aryl group or arylalkyl group, p denotes an integer from 1 to 3, q and r denote integers from 0 to 2 and p+q+r is equal to 3. Also, the amine (I) can be produced with high selectivity and highly economically by reacting a primary amine with an aminocarboxylic acid to run amidation. An amine represented by the formula (1), its salt or quaternary ammonium salt are also provided: Formula (1)
    • 本发明提供一种毛发化妆品,其含有由式(I)表示的胺类的毛发化妆品,其能够赋予毛发润湿后的毛发,柔软性,平滑性,油性感,柔软性,梳理容易性。 式(I)(其中,R 1表示碳原子数为8〜40的烷基或烯基或由式R 5 O-(AO)表示的基团n -C m H 2m - (R 5表示碳原子数为8〜40的碳原子数为8〜40的烷基或烯基) 原子,A表示C2-3亚烷基,n表示平均为0〜30的数,m表示2或3的整数),R2表示C1-5亚烷基,R3表示H,C1-24烷基 基团,烯基或羟基烷基或C 6-28芳基或芳烷基,R 4表示H,C 1-5烷基,亚烷基或羟烷基或C 6-28芳基或芳烷基,p表示 1至3,q和r表示0至2的整数,p + q + r等于3.另外,胺(I)可以高 选择性和高度经济地通过伯胺与氨基羧酸反应进行酰胺化反应。 还提供了由式(1)表示的胺,其盐或季铵盐:式(1)
    • 5. 发明申请
    • Hair cosmetic, aminocarboxylic acid amide and method for producing the same
    • 毛发化妆品,氨基羧酸酰胺及其制造方法
    • US20050091763A1
    • 2005-05-05
    • US10997945
    • 2004-11-29
    • Katsuhisa InoueTakeshi KaharuTohru Katoh
    • Katsuhisa InoueTakeshi KaharuTohru Katoh
    • C07C237/08C07D295/15A61K7/13
    • C07D295/15A61K8/42A61Q5/006A61Q5/02A61Q5/06A61Q5/12C07C237/08
    • A hair cosmetic which can impart, to hairs, flexibility, smoothness and oily feeling when the hairs are wetted and smoothness, softness and combing easiness after the hairs are dried are provided, the hair cosmetic comprising an amine represented by the formula (I): Formula (I) (wherein R1 represents a C8-40 alkyl group or alkenyl group or a group represented by the formula R5O—(AO)n—CmH2m—(R5 represents a C8-40 alkyl group or alkenyl group having 8 to 40 carbon atoms, A represents a C2-3 alkylene group, n denotes a number from 0 to 30 in average and m denotes an integer of 2 or 3), R2 represents a C1-5 alkylene group, R3 represents H, a C1-24 alkyl group, alkenyl group or hydroxyalkyl group or a C6-28 aryl group or arylalkyl group, R4 represents H, a C1-5 alkyl group, alkylene group or hydroxyalkyl group or a C6-28 aryl group or arylalkyl group, p denotes an integer from 1 to 3, q and r denote integers from 0 to 2 and p+q+r is equal to 3. Also, the amine (I) can be produced with high selectivity and biaghly economically by reacting a primary amine with an aminocarboxylic acid to run amidation. An amine represented by the formula (1), its salt or quaternary ammonium salt are also provided: Formula (1)
    • 本发明提供一种毛发化妆品,其特征在于,含有由式(I)表示的胺类的毛发化妆品,其能够赋予毛发润湿后的毛发,柔软性,平滑性,油性感,柔软性,梳理容易性。 式(I)(其中R 1表示C 8-20烷基或烯基或由式R 5 O表示的基团) - (AO)N 2 -C(O)H 2 - (R 5)表示C 8 - 40个碳原子数为8〜40的烷基或烯基,A表示C 2-3亚烷基,n表示平均为0〜30的数,m表示 2或3),R 2表示C 1-5亚烷基,R 3表示H,C 1-24 烷基,烯基或羟烷基或C 6-28芳基或芳烷基,R 4表示H,C 1〜 5个烷基,亚烷基或羟烷基或C 1 芳基或芳烷基,p表示1〜3的整数,q和r表示0〜2的整数,p + q + r等于3.另外,胺(I )可以通过使伯胺与氨基羧酸反应进行酰胺化而以高选择性和经济地生产。 还提供了由式(1)表示的胺,其盐或季铵盐:式(1)
    • 6. 发明授权
    • Detergent composition
    • 洗涤剂组成
    • US08877702B2
    • 2014-11-04
    • US13383497
    • 2010-07-14
    • Masato NomuraKatsuhisa InoueHisato Fukuda
    • Masato NomuraKatsuhisa InoueHisato Fukuda
    • C11D17/00C11D1/83C11D1/29C11D1/722
    • C11D1/8305C11D1/29C11D1/722C11D1/83
    • The present invention relates to the detergent composition, containing (a) a nonionic surfactant represented by the formula (1); and (b) a sulfuric acid ester salt represented by the formula (2): R—O-(EO)m—(PO)n-(EO)m′—H  (1) wherein, R represents a hydrocarbon group having 6 to 24 carbon atoms; EO represents an ethyleneoxy group; PO represents a propyleneoxy group; m=0.1 to 25; m′=0 to 24.9; m+m′=0.5 to 25; and n=0.1 to 10; with the proviso that (EO)m, (PO)n, and (EO)m′ are arranged in a block addition mode in this order; R1—O—(PO)x-(EO)y—SO3M  (2) wherein, R1 represents a hydrocarbon group having 6 to 24 carbon atoms; x=0.1 to 10; y=0 to 30; (PO)x and (EO)y are arranged in any order in any addition mode, being a block addition or a random addition, M is a counter ion.
    • 本发明涉及含有(a)由式(1)表示的非离子表面活性剂的洗涤剂组合物。 和(b)由式(2)表示的硫酸酯盐:R-O-(EO)m-(PO)n-(EO)m'-H(1)其中,R表示具有6 至24个碳原子; EO表示乙烯氧基; PO表示丙烯氧基; m = 0.1〜25; m'= 0〜24.9; m + m'= 0.5〜25; n = 0.1〜10; 条件是(EO)m,(PO)n和(EO)m'按顺序排列成块加成模式; R1-O-(PO)x-(EO)y-SO3M(2)其中R1表示碳原子数为6〜24的烃基; x = 0.1〜10; y = 0〜30; (PO)x和(EO)y以任何加成模式排列,为嵌段加成或无规加成,M为抗衡离子。