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1. 发明申请

US20090008575A1 PARTICLE IRRADIATION APPARATUS, PARTICLE BEAM IRRADIATION METHOD AND PARTICLE TREATMENT SYSTEM 审中-公开
标题翻译：粒子辐射装置，颗粒光束辐射方法和颗粒处理系统
公开(公告)号：US20090008575A1
公开(公告)日：2009-01-08
申请号：US12119787
申请日：2008-05-13
申请人： Takashi OKAZAKI , Hisataka Fujimaki , Shinichiro Fujitaka , Rintaro Fujimoto , Yusuke Fujii , Kazuo Hiramoto
发明人： Takashi OKAZAKI , Hisataka Fujimaki , Shinichiro Fujitaka , Rintaro Fujimoto , Yusuke Fujii , Kazuo Hiramoto
IPC分类号： A61N5/00
CPC分类号： A61N5/10 , A61N2005/1087 , A61N2005/1095
摘要： A particle irradiation apparatus and a particle beam irradiation method that controls the energy and irradiation dose of a particle beam to form a high dose region having a high uniformity of depth-directional spread (Spread Out Bracici Peak, referred to as SOBP). A SOBP having a steep falling edge of the dose distribution on the deep side from the body surface is formed based on a method of superimposing SOBPs each having a small dose distribution width to form a desired SOBP. An energy-spread-device forms a first SOBP having a small dose distribution width; and an energy spread device 2 forms a second SOBP having a small dose distribution width and a steep falling edge of the dose distribution at the deepest portion from the body surface. The thus formed SOBPs are superimposed to form a SOBP having a length suitable for the target region.
摘要翻译：粒子照射装置和粒子束照射方法，其控制粒子束的能量和照射剂量以形成具有高均匀度的深度方向扩展的高剂量区域（Spread Out Bracici Peak，称为SOBP）。基于叠加具有小剂量分布宽度的SOBP以形成期望的SOBP的方法形成具有从身体表面的深侧的剂量分布的陡峭下降边缘的SOBP。能量扩散装置形成具有小剂量分布宽度的第一SOBP; 并且能量扩散装置2形成具有小的剂量分布宽度和剂量分布的陡峭下降边缘的第二SOBP，其在距离体表的最深部分。将如此形成的SOBP叠加以形成具有适合于目标区域的长度的SOBP。

2. 发明授权

US08847179B2 Treatment planning apparatus and particle therapy system 有权
标题翻译：治疗计划设备和颗粒治疗系统
公开(公告)号：US08847179B2
公开(公告)日：2014-09-30
申请号：US13448553
申请日：2012-04-17
申请人： Shinichiro Fujitaka , Yusuke Fujii , Rintaro Fujimoto , Kazuo Hiramoto , Hiroshi Akiyama
发明人： Shinichiro Fujitaka , Yusuke Fujii , Rintaro Fujimoto , Kazuo Hiramoto , Hiroshi Akiyama
IPC分类号： G21K5/04 , A61N5/10
CPC分类号： A61N5/1043 , A61N5/1036 , A61N5/1045 , A61N2005/1087
摘要： A charged particle beam reduces treatment time in the uniform scanning or in the conformal layer stacking irradiation. In the uniform scanning, an optimum charged particle beam scan path for uniformly irradiating a collimator aperture area is calculated. In the conformal layer stacking irradiation, an optimum charged particle beam scan path for uniformly irradiating a multi-leaf collimator aperture area of each layer for each of the layers obtained by partitioning the target volume is calculated. Alternatively, a minimum irradiation field size that covers the multi-leaf collimator aperture area of each layer is calculated, and a scan path corresponding to the irradiation field size, prestored in a memory of a particle therapy control apparatus, is selected. The charged particle beam scan path is optimally changed in the lateral directions in conformity with the collimator aperture area in the uniform scanning or in each layer in the conformal layer stacking irradiation.
摘要翻译：带电粒子束在均匀扫描或共形层层叠照射中减少处理时间。在均匀扫描中，计算用于均匀照射准直器孔径面积的最佳带电粒子束扫描路径。在保形层堆积照射中，计算用于对通过划分目标体积获得的每个层的各层的多叶准直器孔径面均匀地照射的最佳带电粒子束扫描路径。或者，计算覆盖各层的多叶准直器开口面积的最小照射场尺寸，并且选择预先存储在粒子治疗控制装置的存储器中的与照射场尺寸对应的扫描路径。带电粒子束扫描路径在均匀扫描中或在共形层堆积照射中每层中的准直器开口面积在横向上最佳地改变。

3. 发明授权

US08874385B2 Radiation detector and verification technique of positioning accuracy for radiation detector 有权
标题翻译：辐射探测器和辐射探测器定位精度验证技术
公开(公告)号：US08874385B2
公开(公告)日：2014-10-28
申请号：US13013018
申请日：2011-01-25
申请人： Taisuke Takayanagi , Hideaki Nihongi , Yusuke Fujii , Hiroshi Akiyama , Masahiro Tadokoro , Rintaro Fujimoto
发明人： Taisuke Takayanagi , Hideaki Nihongi , Yusuke Fujii , Hiroshi Akiyama , Masahiro Tadokoro , Rintaro Fujimoto
IPC分类号： G01T1/00 , G01T1/29 , G01T1/185 , G01T1/24
CPC分类号： G01T1/29 , G01T1/185 , G01T1/241 , G01T1/2935
摘要： The present invention provides, at low cost, a multilayer radiation detector whose position relative to a beam axis can be verified. The radiation detector includes a plurality of sensors that react to radiation and are stacked in parallel inlayers in a traveling direction of the radiation. The sensors are each sectioned into a central region including the center of the sensor and another region surrounding the central region. The radiation detector independently measures signals measured by the central regions and signals measured by the other regions. Thus, the position of the radiation detector can be verified.
摘要翻译：本发明以低成本提供可以验证其相对于光束轴的位置的多层辐射检测器。辐射检测器包括多个对辐射作出反应的传感器，并且在辐射的行进方向上并联堆叠在平行的嵌入层中。传感器各自被分成包括传感器的中心和围绕中心区域的另一区域的中心区域。辐射检测器独立地测量由中心区域测量的信号和由其他区域测量的信号。因此，可以验证放射线检测器的位置。

4. 发明授权

US08581218B2 Treatment planning system, device for calculating a scanning path and particle therapy system 有权
公开(公告)号：US08581218B2
公开(公告)日：2013-11-12
申请号：US13171704
申请日：2011-06-29
申请人： Rintaro Fujimoto , Yoshihiko Nagamine , Masumi Umezawa , Toru Umekawa , Yusuke Fujii , Hiroshi Akiyama
发明人： Rintaro Fujimoto , Yoshihiko Nagamine , Masumi Umezawa , Toru Umekawa , Yusuke Fujii , Hiroshi Akiyama
IPC分类号： A61N5/00 , G21G5/00
CPC分类号： A61N5/1065 , A61N5/103 , A61N5/1043 , A61N2005/1087
摘要： In a particle therapy treatment planning system for creating treatment plan data, the movement of a target (patient's affected area) is extracted from plural tomography images of the target, and the direction of scanning is determined by projecting the extracted movement on a scanning plane scanned by scanning magnets. Irradiation positions are arranged on straight lines parallel with the scanning direction making it possible to calculate a scanning path for causing scanning to be made mainly along the direction of movement of the target. The treatment planning system can thereby realize dose distribution with improved uniformity.

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