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    • 2. 发明申请
    • MEDICATED PATCH
    • 医疗护理
    • US20110002976A1
    • 2011-01-06
    • US12919715
    • 2009-02-09
    • Naoki YamamotoKumi MorimotoAkio TakeuchiKenji Ishigaki
    • Naoki YamamotoKumi MorimotoAkio TakeuchiKenji Ishigaki
    • A61F13/02A61K31/4985
    • A61K31/4985A61K9/7061
    • Provided is a medicated patch containing a medicinal agent, an adhesive base material and a tackifier, where the medicinal agent is varenicline or a pharmaceutically acceptable salt thereof, the adhesive base material is a rubbery adhesive base material and the tackifier is a rosin-based tackifier selected from the group consisting of rosin, rosin derivatives and hydrogenated products of the foregoing, or a non-rosin-based tackifier selected from the group consisting of aliphatic hydrocarbon resins and alicyclic hydrocarbon resins, and when a non-rosin-based tackifier is added as the tackifier, a solubilizer for the medicinal agent is further added, the solubilizer containing an alcohol-based solubilizer having at least a solubility parameter of 20-35.
    • 本发明提供一种含有药剂,粘合剂基材和增粘剂的药膏,其中药剂为伐仑克林或其药学上可接受的盐,粘合剂基材为橡胶性粘合剂基材,增粘剂为松香类增粘剂 选自上述的松香,松香衍生物和氢化产物,或选自脂肪族烃树脂和脂环族烃树脂的非松香类增粘剂,并且当添加非松香类增粘剂时 作为增粘剂,还添加了用于药剂的增溶剂,该增溶剂含有至少具有20-35的溶解度参数的醇基增溶剂。
    • 6. 发明授权
    • Medicated patch
    • 补药
    • US08871249B2
    • 2014-10-28
    • US12919715
    • 2009-02-09
    • Naoki YamamotoKumi MorimotoAkio TakeuchiKenji Ishigaki
    • Naoki YamamotoKumi MorimotoAkio TakeuchiKenji Ishigaki
    • A61F13/00A61K31/4985A61K9/70
    • A61K31/4985A61K9/7061
    • Provided is a medicated patch containing a medicinal agent, an adhesive base material and a tackifier, where the medicinal agent is varenicline or a pharmaceutically acceptable salt thereof, the adhesive base material is a rubbery adhesive base material and the tackifier is a rosin-based tackifier selected from the group consisting of rosin, rosin derivatives and hydrogenated products of the foregoing, or a non-rosin-based tackifier selected from the group consisting of aliphatic hydrocarbon resins and alicyclic hydrocarbon resins, and when a non-rosin-based tackifier is added as the tackifier, a solubilizer for the medicinal agent is further added, the solubilizer containing an alcohol-based solubilizer having at least a solubility parameter of 20-35.
    • 本发明提供一种含有药剂,粘合剂基材和增粘剂的药膏,其中药剂为伐仑克林或其药学上可接受的盐,粘合剂基材为橡胶性粘合剂基材,增粘剂为松香类增粘剂 选自上述的松香,松香衍生物和氢化产物,或选自脂肪族烃树脂和脂环族烃树脂的非松香类增粘剂,并且当添加非松香类增粘剂时 作为增粘剂,还添加了用于药剂的增溶剂,该增溶剂含有至少具有20-35的溶解度参数的醇基增溶剂。