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1. 发明授权

US4259316A Oral composition for caries prophylaxis 失效
标题翻译：龋齿预防口服成分
公开(公告)号：US4259316A
公开(公告)日：1981-03-31
申请号：US79801
申请日：1979-09-28
申请人： Syozi Nakashima , Tosiyuki Ozawa , Takashi Ujiie , Takeshi Naganuma , Satoshi Hayashi , Yoshihito Ochiai
发明人： Syozi Nakashima , Tosiyuki Ozawa , Takashi Ujiie , Takeshi Naganuma , Satoshi Hayashi , Yoshihito Ochiai
IPC分类号： A61K6/00 , A61K8/21 , A61K8/55 , A61K31/70 , A61K33/16 , A61K33/24 , A61P1/02 , A61Q11/00 , A61K7/18
CPC分类号： A61Q11/00 , A61K33/16 , A61K33/24 , A61K8/21 , A61K8/55
摘要： An oral composition for caries prophylaxis which comprises 0.04 to 10% by weight of stannous fluoride and not less than 0.1% by weight of a phytic acid compound, the molar ratio of the phytic acid compound to stannous fluoride being in the range of from 0.01:1 to 4:1 and the composition being acidic, is effective in inhibiting dental caries and shows a prolonged effect after application. The oral composition may be used as mouthwashes, oral bands, topical solutions, cavity sealers, prophylactic pastes, dentifrices, dental flosses and the like.
摘要翻译：一种龋齿预防用口腔用组合物，其含有0.04〜10重量％的氟化亚锡和不少于0.1重量％的植酸化合物，所述植酸化合物与氟化亚锡的摩尔比为0.01： 1〜4：1，组合物呈酸性，有效抑制龋齿，施用后效果延长。口腔用组合物可以用作漱口剂，口服胶带，局部溶液，空腔封口剂，预防糊剂，洁牙剂，牙线等。

2. 发明授权

US4335102A Oral composition for caries prophylaxis 失效
标题翻译：龋齿预防口服成分
公开(公告)号：US4335102A
公开(公告)日：1982-06-15
申请号：US185964
申请日：1980-09-09
申请人： Syozi Nakashima , Tosiyuki Ozawa , Takeshi Naganuma , Takashi Ujiie , Satoshi Hayashi , Yoshihito Ochiai
发明人： Syozi Nakashima , Tosiyuki Ozawa , Takeshi Naganuma , Takashi Ujiie , Satoshi Hayashi , Yoshihito Ochiai
IPC分类号： A61K8/00 , A61K8/19 , A61K8/20 , A61K8/21 , A61K8/23 , A61K8/24 , A61K8/36 , A61K8/362 , A61K8/365 , A61K8/55 , A61Q11/00 , A61K7/18 , A61K9/68
CPC分类号： A61K8/19 , A61K8/21 , A61K8/24 , A61K8/55 , A61Q11/00
摘要： An oral composition for caries prophylaxis which comprises a highly soluble stannous compound such as stannous fluoride preferably in an amount of 0.03 to 5% by weight of the composition as stannous tin, a difficultly soluble stannous compound such as stannous pyrophosphate preferably in an amount of 0.05 to 10% by weight of the composition as stannous tin, a phytic acid compound such as sodium phytate preferably in an amount of 0.1 to 20% by weight of the composition, and the pH of the composition being preferably acidic. A portion of the difficultly soluble stannous compound may be in a precipitate form. The oral composition which may be used as dentifrices, prophylactic pastes, dental flosses and the like permits n.sup.2+ ions to exert its effect because the storage stability is high enough to maintain the increased concentration of active dissolved stannous ions in the composition for a prolonged period of time and can render the tooth enamel more resistant to acid attack when applied to teeth.
摘要翻译：一种用于龋齿预防的口腔用组合物，其包含高度可溶的亚锡化合物，例如氟化亚锡，优选为锡组合物的0.03〜5重量％，难溶的亚锡化合物如焦磷酸亚锡，优选为0.05 至10重量％的组合物，植酸盐化合物如植酸钠，优选为组合物重量的0.1至20重量％，并且组合物的pH优选为酸性。一部分难溶的亚锡化合物可以是沉淀形式。可以用作洁牙剂，预防糊剂，牙线等的口服组合物允许n2 +离子发挥其作用，因为储存稳定性足够高以保持组合物中活性溶解的亚锡离子的浓度增加更长时间时间可以使牙齿牙齿在施加于牙齿时更耐酸侵蚀。

3. 发明授权

US4363794A Oral composition for caries prophylaxis 失效
标题翻译：龋齿预防口服成分
公开(公告)号：US4363794A
公开(公告)日：1982-12-14
申请号：US949031
申请日：1978-10-06
申请人： Yoshihito Ochiai , Syozi Nakashima , Midori Hayashi
发明人： Yoshihito Ochiai , Syozi Nakashima , Midori Hayashi
IPC分类号： A61K6/00 , A61K6/02 , A61K8/19 , A61K8/20 , A61K8/21 , A61K8/36 , A61K8/362 , A61K8/365 , A61K8/67 , A61K31/19 , A61K33/16 , A61K33/24 , A61Q11/00 , C02F5/08 , A61K7/18 , A61K7/16 , A61K33/42
CPC分类号： A61Q11/00 , A61K6/0067 , A61K8/19 , A61K8/21 , A61K8/36 , A61K8/362 , A61K8/365 , A61K8/676
摘要： An oral composition is disclosed which comprises a stannous salt such as stannous fluoride, a water-soluble fluoride salt such as sodium fluoride and an orally acceptable acid such as L-ascorbic acid, lactic acid, malonic acid, tartaric acid, citric acid, hydrochloric acid and pyrophosphoric acid, the molar ratio of fluoride ion to stannous ion being in the range of 3.2 to 7:1, preferably 3.5-6:1, in an aqueous condition and the pH of the composition being in the range of from 2 to 4. The composition exhibits excellent effects on the inhibition of dental caries.
摘要翻译：公开了一种口服组合物，其包含亚锡盐如氟化亚锡，水溶性氟化物盐如氟化钠和口服可接受的酸如L-抗坏血酸，乳酸，丙二酸，酒石酸，柠檬酸，盐酸酸和焦磷酸，氟化物离子与亚锡离子的摩尔比在水溶液条件下在3.2至7:1的范围内，优选3.5-6:1，组合物的pH在2至该组合物对抑制龋齿表现出极好的效果。

4. 发明授权

US4144646A Torsional ultrasonic vibrators 失效
标题翻译：扭转超声波振动器
公开(公告)号：US4144646A
公开(公告)日：1979-03-20
申请号：US746818
申请日：1976-12-02
申请人： Kiyochika Takemoto , Yasuo Suzuki , Yoshihito Ochiai , Syozi Nakashima , Midori Hayashi
发明人： Kiyochika Takemoto , Yasuo Suzuki , Yoshihito Ochiai , Syozi Nakashima , Midori Hayashi
IPC分类号： A61C17/20 , A61C3/00
CPC分类号： A61C17/20
摘要： A torsional ultrasonic vibrator particularly adapted for treating teeth by exposing them to ultrasonic waves in the presence of a tooth-decay retarding agent which engages the teeth. A shaft which has a central axis has fixed thereto a blade which projects from the latter axis while having a size small enough to be situated in the mouth of an individual to be treated and large enough to extend along a plurality of teeth in the mouth. A vibrator is operatively connected with this shaft for angularly oscillating the same about the above axis at an ultrasonic frequency.
摘要翻译：一种扭转超声波振动器，特别适用于在啮合牙齿的牙齿衰减剂的存在下将它们暴露于超声波处理牙齿。具有中心轴线的轴固定有从后一轴线突出的叶片，同时具有足够小的尺寸，以便位于要处理的个体的口中并且足够大以沿着嘴中的多个齿延伸。振动器与该轴可操作地连接，以超声频率围绕上述轴线以角度方式摆动振动器。

5. 发明授权

US4127125A Devices for transmitting ultrasonic waves to teeth 失效
标题翻译：用于将超声波发送到牙齿的装置
公开(公告)号：US4127125A
公开(公告)日：1978-11-28
申请号：US752894
申请日：1976-12-21
申请人： Kiyochika Takemoto , Yasuo Suzuki , Yoshihito Ochiai , Syozi Nakashima , Midori Hayashi
发明人： Kiyochika Takemoto , Yasuo Suzuki , Yoshihito Ochiai , Syozi Nakashima , Midori Hayashi
IPC分类号： A61C17/20 , A61C19/06 , A61M31/00
CPC分类号： A61C17/20
摘要： For the purpose of forming a reinforcing layer of a decay-retarding agent on the surface of teeth, a device is provided for transmitting ultrasonic waves to the teeth while the latter are in contact with a decay-retarding agent. The device includes an enclosure which is adapted to contain a medium for transmitting ultrasonic waves, this enclosure including a sheet material which defines a hollow interior space in which an ultrasonic wave transmitting medium is adapted to be located. This sheet material of the enclosure has the property of being impermeable to the ultrasonic wave transmitting medium, so that the latter cannot pass through the sheet material. In addition, the sheet material has the property of transmitting ultrasonic waves therethrough. Thus, when a part of the sheet material is situated in the immediate vicinity of a tooth in contact with a decay-retarding agent which also engages the tooth, ultrasonic waves can be transmitted through the medium and through the sheet material so as to act on the decay-retarding agent and the teeth to form thereon a reinforcing layer of the decay-retarding agent.
摘要翻译：为了在齿表面上形成减阻剂的增强层的目的是提供一种用于在超声波与衰减剂接触的同时将超声波传递到齿的装置。该装置包括适于容纳用于传输超声波的介质的外壳，该外壳包括限定超声波传输介质适于定位的中空内部空间的片材。外壳的这种片材具有对超声波传输介质不可渗透的特性，使得后者不能通过片材。此外，片材具有通过其传输超声波的性质。因此，当片材的一部分位于与还与齿接合的衰减剂接触的齿的紧邻附近时，超声波可以通过介质传播并通过片材以作用于所述衰减剂和所述齿在其上形成所述衰减剂的增强层。

6. 发明授权

US4162576A Appliances for treating teeth 失效
标题翻译：牙齿治疗器具
公开(公告)号：US4162576A
公开(公告)日：1979-07-31
申请号：US780367
申请日：1977-03-23
申请人： Kiyochika Takemoto , Yasuo Suzuki , Yoshihito Ochiai , Syozi Nakashima , Midori Hayashi
发明人： Kiyochika Takemoto , Yasuo Suzuki , Yoshihito Ochiai , Syozi Nakashima , Midori Hayashi
IPC分类号： A61C1/07 , A61C17/20 , A61C19/06 , A61C3/00
CPC分类号： A61C17/20 , A61C19/06
摘要： An appliance for treating teeth, such as human teeth, by providing them with a reinforcing acid-resistant layer of a tooth decay retarding agent. The appliance includes a vibrator for producing ultrasonic vibrations, this vibrator terminating in an elongated vibratory tip. A casing houses the vibrator and has a tubular open end region in which the tip is at least partly accommodated. This tubular open end region of the casing carries an elastic membrane wall which extends across the tubular open end region of the casing and through which the tip extends so that the tip has a free end situated outwardly beyond this elastic membrane wall. The elastic membrane wall fluid-tightly engages the vibratory tip while surrounding the latter, and the membrane wall maintains this fluid-tight engagement with the tip during vibration thereof. The tubular open end of the casing is adapted to be attached to a tray which has a hollow interior provided with a liquid vibration-transmitting medium, the tip piercing into the interior of the tray to engage the liquid medium therein when the tray is attached to the casing at the tubular open end region thereof.
摘要翻译：通过为牙齿提供抗衰老增强剂的牙齿衰老剂，可以治疗牙齿等器具。该器具包括用于产生超声波振动的振动器，该振动器终止于细长的振动尖端。壳体容纳振动器并且具有至少部分地容纳尖端的管状开口端区域。壳体的这种管状开口端区域承载弹性膜壁，该弹性膜壁延伸穿过壳体的管状开口端区域，并且尖端延伸通过该弹性膜壁，使得尖端具有位于该弹性膜壁外侧的自由端。弹性膜壁围绕振动尖端流体紧密地接合，并且膜壁在其振动期间保持与尖端的流体密封接合。壳体的管状开口端适于附接到具有设置有液体振动传递介质的中空内部的托盘，当托盘附接到托盘时，尖端刺入托盘的内部以接合其中的液体介质壳体在其管状开口端区域。

7. 发明授权

US4144882A Device for exposing teeth to radiation of ultrasonic waves 失效
标题翻译：用于将牙齿暴露于超声波辐射的装置
公开(公告)号：US4144882A
公开(公告)日：1979-03-20
申请号：US751270
申请日：1976-12-17
申请人： Kiyochika Takemoto , Yasuo Suzuki , Yoshihito Ochiai , Syozi Nakashima , Midori Hayashi
发明人： Kiyochika Takemoto , Yasuo Suzuki , Yoshihito Ochiai , Syozi Nakashima , Midori Hayashi
IPC分类号： A61C19/06 , A61C17/20 , A61M31/00
CPC分类号： A61C17/20
摘要： A device for exposing teeth to radiation of ultrasonic waves while the teeth are contacted by a decay-retarding agent, for forming a reinforcing layer of the latter agent on the teeth. In addition to a generator for generating ultrasonic waves, the device includes a support structure which carries a plate capable of transmitting and reflecting the ultrasonic waves. The latter plate is situated between the generator and teeth toward which waves are generally directed from the generator, so that the latter waves are received by this plate which transmits part of the waves through the plate to the teeth at the side of the plate opposite from the generator while another part of the waves are reflected by this plate away from the teeth which receive the transmitted waves, so that in this way the reflected waves may be utilized to treat additional teeth.
摘要翻译：一种用于在牙齿与衰减剂接触的同时将牙齿暴露于超声波辐射的装置，用于在牙齿上形成后者的增强层。除了用于产生超声波的发生器之外，该装置还包括支撑结构，其承载能够发射和反射超声波的板。后者的板位于发电机和齿之间，波形通常从发生器引导，使得后者的波被该板接收，该波片将波的一部分波穿过板传送到与板相反的一侧的齿发生器，而另一部分波被该板反射离开接受透射波的齿，使得以这种方式，可以利用反射波来处理额外的齿。

8. 发明授权

US4645662A Oral composition 失效
标题翻译：口语构成
公开(公告)号：US4645662A
公开(公告)日：1987-02-24
申请号：US758723
申请日：1985-07-25
申请人： Syozi Nakashima , Akinori Takahashi , Nobuo Suganuma , Satoshi Ito
发明人： Syozi Nakashima , Akinori Takahashi , Nobuo Suganuma , Satoshi Ito
IPC分类号： A61K8/00 , A61K6/00 , A61K8/26 , A61K8/36 , A61K8/362 , A61K8/365 , A61Q11/00 , A61K7/16 , A61K7/18 , A61K7/22 , A61K7/24
CPC分类号： A61Q11/00 , A61K8/26 , A61K8/362 , A61K8/365
摘要： An oral composition for preventing and remedying dentinal hypersensitivity which comprises containing therein aluminum and a carboxylate compound in solubilized state, with the molar ratio of the carboxylate compound to aluminum being lower than 6, and having a pH value higher than 5.
摘要翻译：一种用于预防和治疗牙质超敏反应的口服组合物，其包括在其中含有铝和羧化合物溶解状态，羧酸酯化合物与铝的摩尔比低于6，pH值高于5。

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