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1. 发明申请

US20120035685A1 USER INTERFACE SYSTEM FOR USE WITH MULTIPOLAR PACING LEADS 有权
标题翻译：用户界面系统，用于多用途铅笔
公开(公告)号：US20120035685A1
公开(公告)日：2012-02-09
申请号：US13198499
申请日：2011-08-04
申请人： Sunipa Saha , Kenneth N. Hayes , Keith L. Herrmann , James Kalgren , Aaron R. McCabe , Holly Rockweiler , Shibaji Shome , Krzysztof Z. Siejko
发明人： Sunipa Saha , Kenneth N. Hayes , Keith L. Herrmann , James Kalgren , Aaron R. McCabe , Holly Rockweiler , Shibaji Shome , Krzysztof Z. Siejko
IPC分类号： A61N1/362 , A61N1/05 , A61N1/04
CPC分类号： A61N1/37247 , A61N1/056 , A61N1/36185 , A61N1/3686 , A61N1/37241
摘要： An interactive representation of electrostimulation electrodes or vectors can be provided, such as for configuring combinations of electrostimulation electrodes. In an example, electrodes or test parameters can be presented graphically or in a table. A user interface can be configured to receive user-input designating electrode combinations or vectors for test or for use in programming an implantable or ambulatory medical device. The interface can be used to indicate suggested electrode combinations or vectors in response to a first selection of an electrode. Tests can be performed on electrode combinations and vectors, and the results of the tests can be presented to a user using the interactive representation. In an example, test results can be analyzed by a processor and optionally used to program an implantable or ambulatory medical device.
摘要翻译：可以提供电刺激电极或载体的交互式表示，例如用于配置电刺激电极的组合。在一个示例中，电极或测试参数可以图形化或在表中呈现。用户界面可以被配置为接收用户输入的指定电极组合或矢量，用于测试或用于编程可植入或动态医疗设备。该界面可用于响应于电极的第一选择来指示建议的电极组合或载体。可以对电极组合和载体进行测试，并且可以使用交互式表示向使用者呈现测试结果。在一个示例中，测试结果可以由处理器分析，并且可选地用于编程可植入或动态医疗设备。

2. 发明授权

US09138585B2 User interface system for use with multipolar pacing leads 有权
标题翻译：用于多极起搏线的用户界面系统
公开(公告)号：US09138585B2
公开(公告)日：2015-09-22
申请号：US13198499
申请日：2011-08-04
申请人： Sunipa Saha , Kenneth N. Hayes , Keith L. Herrmann , James Kalgren , Aaron R. McCabe , Holly Rockweiler , Shibaji Shome , Krzysztof Z. Siejko
发明人： Sunipa Saha , Kenneth N. Hayes , Keith L. Herrmann , James Kalgren , Aaron R. McCabe , Holly Rockweiler , Shibaji Shome , Krzysztof Z. Siejko
IPC分类号： A61N1/372 , A61N1/368 , A61N1/36
CPC分类号： A61N1/37247 , A61N1/056 , A61N1/36185 , A61N1/3686 , A61N1/37241
摘要： An interactive representation of electrostimulation electrodes or vectors can be provided, such as for configuring combinations of electrostimulation electrodes. In an example, electrodes or test parameters can be presented graphically or in a table. A user interface can be configured to receive user-input designating electrode combinations or vectors for test or for use in programming an implantable or ambulatory medical device. The interface can be used to indicate suggested electrode combinations or vectors in response to a first selection of an electrode. Tests can be performed on electrode combinations and vectors, and the results of the tests can be presented to a user using the interactive representation. In an example, test results can be analyzed by a processor and optionally used to program an implantable or ambulatory medical device.
摘要翻译：可以提供电刺激电极或载体的交互式表示，例如用于配置电刺激电极的组合。在一个示例中，电极或测试参数可以图形化或在表中呈现。用户界面可以被配置为接收用户输入的指定电极组合或用于测试或用于编程可植入或动态医疗设备的矢量。该界面可用于响应于电极的第一选择来指示所建议的电极组合或载体。可以对电极组合和载体进行测试，并且可以使用交互式表示向使用者呈现测试结果。在一个示例中，测试结果可以由处理器分析，并且可选地用于编程可植入或动态医疗设备。

3. 发明授权

US08565879B2 Method and apparatus for pacing safety margin 有权
标题翻译：起搏安全幅度的方法和装置
公开(公告)号：US08565879B2
公开(公告)日：2013-10-22
申请号：US13071680
申请日：2011-03-25
申请人： Amy Jean Brisben , Shibaji Shome , Kenneth N. Hayes , Yanting Dong , Aaron R. McCabe , Scott A. Meyer , Kevin John Stalsberg
发明人： Amy Jean Brisben , Shibaji Shome , Kenneth N. Hayes , Yanting Dong , Aaron R. McCabe , Scott A. Meyer , Kevin John Stalsberg
IPC分类号： A61N1/08
CPC分类号： A61N1/36585 , A61N1/3712
摘要： An apparatus comprises a cardiac signal sensing circuit, a pacing therapy circuit, and a controller circuit. The controller circuit includes a safety margin calculation circuit. The controller circuit initiates delivery of pacing stimulation energy to the heart using a first energy level, changes the energy level by at least one of: a) increasing the energy from the first energy level until detecting that the pacing stimulation energy induces stable capture, or b) reducing the energy from the first energy level until detecting that the stimulation energy fails to induce capture, and continues changing the stimulation energy level until confirming stable capture or the failure of capture. The safety margin calculation circuit calculates a safety margin of pacing stimulation energy using at least one of a determined stability of a parameter associated with evoked response and a determined range of energy levels corresponding to stable capture or intermittent failure of capture.
摘要翻译：一种装置包括心脏信号感测电路，起搏治疗电路和控制器电路。控制器电路包括安全裕度计算电路。控制器电路使用第一能级开始向心脏传送起搏刺激能量，通过以下至少一种来改变能量水平：a）从第一能量级增加能量直到检测到起搏刺激能量引起稳定的捕获，或 b）减少来自第一能级的能量，直到检测到刺激能量不能诱导捕获，并且继续改变刺激能量水平，直到确认捕获稳定或捕获失败为止。安全裕度计算电路使用与诱发反应相关联的参数的确定的稳定性以及与捕获的稳定捕获或间歇性故障相对应的能量水平的确定范围中的至少一个来计算起搏刺激能量的安全裕度。

4. 发明申请

US20110245890A1 METHOD AND APPARATUS FOR PACING SAFETY MARGIN 有权
标题翻译：防治安全隐患的方法和装置
公开(公告)号：US20110245890A1
公开(公告)日：2011-10-06
申请号：US13071680
申请日：2011-03-25
申请人： Amy Jean Brisben , Shibaji Shome , Kenneth N. Hayes , Yanting Dong , Aaron R. McCabe , Scott A. Meyer , Kevin John Stalsberg
发明人： Amy Jean Brisben , Shibaji Shome , Kenneth N. Hayes , Yanting Dong , Aaron R. McCabe , Scott A. Meyer , Kevin John Stalsberg
IPC分类号： A61N1/08 , A61N1/362
CPC分类号： A61N1/36585 , A61N1/3712
摘要： An apparatus comprises a cardiac signal sensing circuit, a pacing therapy circuit, and a controller circuit. The controller circuit includes a safety margin calculation circuit. The controller circuit initiates delivery of pacing stimulation energy to the heart using a first energy level, changes the energy level by at least one of: a) increasing the energy from the first energy level until detecting that the pacing stimulation energy induces stable capture, or b) reducing the energy from the first energy level until detecting that the stimulation energy fails to induce capture, and continues changing the stimulation energy level until confirming stable capture or the failure of capture. The safety margin calculation circuit calculates a safety margin of pacing stimulation energy using at least one of a determined stability of a parameter associated with evoked response and a determined range of energy levels corresponding to stable capture or intermittent failure of capture.
摘要翻译：一种装置包括心脏信号感测电路，起搏治疗电路和控制器电路。控制器电路包括安全裕度计算电路。控制器电路使用第一能级开始向心脏传送起搏刺激能量，通过以下至少一种来改变能量水平：a）从第一能量级增加能量直到检测到起搏刺激能量引起稳定的捕获，或 b）减少来自第一能级的能量，直到检测到刺激能量不能诱导捕获，并且继续改变刺激能量水平，直到确认捕获稳定或捕获失败为止。安全裕度计算电路使用与诱发反应相关联的参数的确定的稳定性以及与捕获的稳定捕获或间歇性故障相对应的能量水平的确定范围中的至少一个来计算起搏刺激能量的安全裕度。

5. 发明申请

US20120303082A1 Adjusting Cardiac Pacing Response Sensing Intervals 审中-公开
标题翻译：调整心脏起搏反应感测间隔
公开(公告)号：US20120303082A1
公开(公告)日：2012-11-29
申请号：US13306611
申请日：2011-11-29
申请人： Yanting Dong , Shibaji Shome , Aaron McCabe , Amy J. Brisben , Clayton Foster , David W. Yost , Kenneth N. Hayes
发明人： Yanting Dong , Shibaji Shome , Aaron McCabe , Amy J. Brisben , Clayton Foster , David W. Yost , Kenneth N. Hayes
IPC分类号： A61N1/37 , A61N1/365
CPC分类号： A61N1/371 , A61B5/0422 , A61B5/04525 , A61B5/0456 , A61B5/4836 , A61B5/7217 , A61B5/7267 , A61N1/3712
摘要： Discrimination between different types of possible cardiac pacing responses may depend on the timing of expected features that are sensed within a temporal framework. The temporal framework may include classification intervals, blanking periods and appropriately timed back up paces. The classification intervals and blanking periods of the temporal framework are intervals of time that have time parameters that include start time, end time, and length. The relationships and timing parameters of the elements of the temporal framework, e.g., blanking periods, classification intervals, delay periods, and backup pacing, should support detection of features used to discriminate between different types of pacing responses. As the system learns the morphology of the particular patient by analyzing the waveform of the pacing response signal, the temporal framework for pacing response determination may be adjusted to accommodate the individual patient.
摘要翻译：不同类型的可能心脏起搏反应之间的歧视可能取决于在时间框架内感测到的预期特征的时间。时间框架可以包括分类间隔，消隐期和适当定时的后台步数。时间框架的分类间隔和消隐期是具有包括开始时间，结束时间和长度的时间参数的时间间隔。时间框架的元素的关系和定时参数，例如消隐期，分类间隔，延迟周期和备份起搏应该支持用于区分不同类型的起搏响应的特征的检测。当系统通过分析起搏响应信号的波形来学习特定患者的形态时，可调整起搏响应确定的时间框架以适应个体患者。

6. 发明授权

US08369945B2 Implantable cardioverter defibrillator with programmable capacitor charging level 有权
标题翻译：可植入式心律转复除颤器，具有可编程电容充电等级
公开(公告)号：US08369945B2
公开(公告)日：2013-02-05
申请号：US13190107
申请日：2011-07-25
申请人： Nick A. Youker , Kenneth N. Hayes , William J. Linder
发明人： Nick A. Youker , Kenneth N. Hayes , William J. Linder
IPC分类号： A61N1/39
CPC分类号： A61N1/3708 , A61N1/37235 , A61N1/3925 , A61N1/3956 , A61N1/3975 , A61N1/3981
摘要： An implantable cardioverter defibrillator (ICD) has a programmable ICD energy level corresponding to the maximum defibrillation energy deliverable with each defibrillation shock pulse. The ICD energy level is programmable within the maximum energy capacity of the defibrillation capacitor(s) of the ICD. In various embodiments, after a user enters the ICD energy level, one or more corresponding ICD performance parameters are presented. Restrictions are applied to the energy level programming of the ICD to ensure the predictability of the one or more ICD performance parameters.
摘要翻译：植入式心律转复除颤器（ICD）具有对应于每个除颤冲击脉冲可递送的最大除颤能量的可编程ICD能量水平。 ICD能量级可在ICD的除颤电容器的最大能量容量内编程。在各种实施例中，在用户进入ICD能级之后，呈现一个或多个相应的ICD性能参数。限制适用于ICD的能量级编程，以确保一个或多个ICD性能参数的可预测性。

7. 发明授权

US08452405B2 Methods and systems for mitigating the occurrence of arrhythmia during atrial pacing 有权
标题翻译：减轻心房起搏心律失常发生的方法和系统
公开(公告)号：US08452405B2
公开(公告)日：2013-05-28
申请号：US12772725
申请日：2010-05-03
申请人： Eric Enrooth , Yanting Dong , Kenneth N. Hayes , Gary T. Seim , Kevin John Stalsberg , Aaron McCabe
发明人： Eric Enrooth , Yanting Dong , Kenneth N. Hayes , Gary T. Seim , Kevin John Stalsberg , Aaron McCabe
IPC分类号： A61N1/362
CPC分类号： A61N1/3712 , A61N1/3622 , A61N1/3714
摘要： Noncaptured atrial paces can result in long-short cardiac cycles which are proarrhythmic for ventricular tachyarrhythmia. Approaches are described which are directed to avoiding proarrhythmic long-short cycles. For cardiac cycles in which the atrial pace captures the atrium, a first post ventricular refractory period (PVARP) and a first A-A interval are used. For cardiac cycles in which the atrial pace does not capture the atrium, both an extended PVARP and an extended A-A interval are used. The A-A interval following a noncaptured atrial pace is extended from an atrial depolarization sensed during the extended PVARP.
摘要翻译：非心房颤动可导致心律失常的心律失常的长时间心脏周期。描述了旨在避免心律失常长时间短周期的方法。对于心房搏动捕获心房的心脏周期，使用第一个心室后不应期（PVARP）和第一个A-A间隔。对于其中心房速度不捕获心房的心脏周期，使用延长的PVARP和延长的A-A间隔。在非扩张性PVARP期间感觉到的心房去极化之后，A-A间隔未被捕获。

8. 发明申请

US20100286743A1 Methods and Systems for Mitigating the Occurrence of Arrhythmia During Atrial Pacing 有权
标题翻译：心房起搏减轻心律失常发生的方法和系统
公开(公告)号：US20100286743A1
公开(公告)日：2010-11-11
申请号：US12772725
申请日：2010-05-03
申请人： Eric K. Enrooth , Yanting Dong , Kenneth N. Hayes , Gary T. Seim , Kevin John Stalsberg , Aaron McCabe
发明人： Eric K. Enrooth , Yanting Dong , Kenneth N. Hayes , Gary T. Seim , Kevin John Stalsberg , Aaron McCabe
IPC分类号： A61N1/37
CPC分类号： A61N1/3712 , A61N1/3622 , A61N1/3714
摘要： Noncaptured atrial paces can result in long-short cardiac cycles which are proarrhythmic for ventricular tachyarrhythmia. Approaches are described which are directed to avoiding proarrhythmic long-short cycles. For cardiac cycles in which the atrial pace captures the atrium, a first post ventricular refractory period (PVARP) and a first A-A interval are used. For cardiac cycles in which the atrial pace does not capture the atrium, both an extended PVARP and an extended A-A interval are used. The A-A interval following a noncaptured atrial pace is extended from an atrial depolarization sensed during the extended PVARP.
摘要翻译：非心房颤动可导致心律失常的心律失常的长时间心脏周期。描述了旨在避免心律失常长时间短周期的方法。对于心房搏动捕获心房的心脏周期，使用第一个心室后不应期（PVARP）和第一个A-A间隔。对于其中心房速度不捕获心房的心脏周期，使用延长的PVARP和延长的A-A间隔。在非扩张性PVARP期间感觉到的心房去极化之后，A-A间隔未被捕获。

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