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1. 发明申请

US20060244963A1 SPATIAL POSITIONING OF SPECTRALLY LABELED BEADS 审中-公开
公开(公告)号：US20060244963A1
公开(公告)日：2006-11-02
申请号：US11425851
申请日：2006-06-22
申请人： Stephen Empedocles , Andrew Watson , Jian Jin
发明人： Stephen Empedocles , Andrew Watson , Jian Jin
IPC分类号： G01J3/28 , G01J3/00
CPC分类号： G01N21/272 , B01J2219/00317 , B01J2219/00432 , B01J2219/005 , B01J2219/00574 , B01J2219/00576 , B01J2219/00578 , B01J2219/00585 , B01J2219/00596 , B01J2219/00648 , B01J2219/00657 , B01J2219/00659 , B01J2219/00677 , B01J2219/00707 , B01J2219/00722 , B01J2219/00743 , B01L3/5025 , B01L3/502715 , B01L3/502761 , B01L3/5085 , B01L3/545 , B01L2200/0668 , B01L2300/021 , B01L2300/0819 , B01L2300/0829 , B01L2400/0454 , B01L2400/0457 , B82Y30/00 , C40B40/06 , C40B60/14 , G01N21/25 , G01N21/253 , G01N21/274 , G01N21/278 , G01N21/6428 , G01N21/6452 , G01N21/6456 , G01N21/6486 , G01N21/6489 , G01N33/54373 , G01N2015/0092 , G01N2015/1472 , G01N2015/1497 , G01N2021/6441 , G01N2021/6482 , G01N2035/00158 , G01N2035/00742 , G01N2035/00752 , G01N2201/04 , G01N2201/06113 , G01N2201/12
摘要： Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.

2. 发明授权

US08405828B2 Spatial positioning of spectrally labeled beads 有权
公开(公告)号：US08405828B2
公开(公告)日：2013-03-26
申请号：US12620475
申请日：2009-11-17
申请人： Stephen Empedocles , Andrew Watson , Jian Jin
发明人： Stephen Empedocles , Andrew Watson , Jian Jin
IPC分类号： G01J3/28 , G01J3/00 , G01J3/30 , G01J3/42 , G01N21/29
CPC分类号： G01N21/272 , B01J2219/00317 , B01J2219/00432 , B01J2219/005 , B01J2219/00574 , B01J2219/00576 , B01J2219/00578 , B01J2219/00585 , B01J2219/00596 , B01J2219/00648 , B01J2219/00657 , B01J2219/00659 , B01J2219/00677 , B01J2219/00707 , B01J2219/00722 , B01J2219/00743 , B01L3/5025 , B01L3/502715 , B01L3/502761 , B01L3/5085 , B01L3/545 , B01L2200/0668 , B01L2300/021 , B01L2300/0819 , B01L2300/0829 , B01L2400/0454 , B01L2400/0457 , B82Y30/00 , C40B40/06 , C40B60/14 , G01N21/25 , G01N21/253 , G01N21/274 , G01N21/278 , G01N21/6428 , G01N21/6452 , G01N21/6456 , G01N21/6486 , G01N21/6489 , G01N33/54373 , G01N2015/0092 , G01N2015/1472 , G01N2015/1497 , G01N2021/6441 , G01N2021/6482 , G01N2035/00158 , G01N2035/00742 , G01N2035/00752 , G01N2201/04 , G01N2201/06113 , G01N2201/12
摘要： Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.

3. 发明授权

US08271379B1 Systems and methods for building a personalized account 有权
标题翻译：用于构建个性化帐户的系统和方法
公开(公告)号：US08271379B1
公开(公告)日：2012-09-18
申请号：US09453800
申请日：1999-12-03
申请人： Andrew Watson
发明人： Andrew Watson
IPC分类号： G06Q40/00
CPC分类号： G06Q40/025
摘要： The present invention allows an applicant to apply for an account based service via a network connection. When an applicant applies for the account based service, he or she is supplied with features that enhance the value of the account based service. The applicant may select from the features provided, determine how this selection may affect the value of the account based service in relation to its cost and determine if he or she wishes to receive the account based service with the added features. Examples of account based services include credit cards, insurance accounts and telecommunications accounts.
摘要翻译：本发明允许申请人通过网络连接申请基于帐户的服务。当申请人申请基于帐户的服务时，他或她被提供增强基于帐户的服务的价值的功能。申请人可以从所提供的特征中进行选择，确定该选择如何影响基于帐户的服务与其成本的价值，并确定他或她是否希望接收具有添加的特征的基于帐户的服务。基于帐户的服务的例子包括信用卡，保险账户和电信帐户。

4. 发明申请

US20120220494A1 COMPOSITIONS AND METHODS FOR MOLECULAR LABELING 有权
标题翻译：用于分子标记的组合物和方法
公开(公告)号：US20120220494A1
公开(公告)日：2012-08-30
申请号：US13398677
申请日：2012-02-16
申请人： Michael Samuels , Jeffrey Charles Olson , Andrew Watson , Keith Brown , Darren Roy Link
发明人： Michael Samuels , Jeffrey Charles Olson , Andrew Watson , Keith Brown , Darren Roy Link
IPC分类号： C40B50/08 , C40B40/06 , C40B40/10 , C40B50/06
CPC分类号： C12N15/1075 , C12Q1/6874 , C40B50/08 , G01N33/5436 , G01N33/58
摘要： The invention provides barcode libraries and methods of making and using them including obtaining a plurality of nucleic acid constructs in which each construct comprises a unique N-mer and a functional N-mer and segregating the constructs into a fluid compartments such that each compartment contains one or more copies of a unique construct. The invention further provides methods for digital PCR and for use of barcode libraries in digital PCR.
摘要翻译：本发明提供条形码文件库及其制备和使用方法，包括获得多个核酸构建体，其中每个构建体包含独特的N-聚体和功能性N-聚体，并将构建体分离成流体隔室，使得每个隔室含有一个或更多的独特构造的副本。本发明还提供数字PCR和数字PCR中条形码库的使用方法。

5. 发明申请

US20070247013A1 Aerodynamic insert for high speed permanent magnet motor 失效
标题翻译：高速永磁电机用气动插件
公开(公告)号：US20070247013A1
公开(公告)日：2007-10-25
申请号：US11407839
申请日：2006-04-20
申请人： Andrew Watson , Kevin Tapper
发明人： Andrew Watson , Kevin Tapper
IPC分类号： H02K21/12 , H02K1/27
CPC分类号： H02K1/2773
摘要： An insert comprising a lightweight structure configured for filling the gaps between axially spaced C-shaped lamination stacks and circumferentially spaced non-magnetic cradles on a permanent magnet rotor. The insert is secured to a rib by a dovetail tongue that fits within a dovetail groove provided along the length of each rib. The insert engages the adjacent cradles and has a circumferential surface that has the same radius of curvature as the top surface of the cradles.
摘要翻译：一种插入物，其包括轻质结构，其构造成用于填充轴向间隔开的C形层压叠层之间的间隙和在永磁转子上的周向间隔开的非磁性支架。插入件通过燕尾舌固定到肋上，燕尾舌装配在沿着每个肋的长度设置的燕尾槽内。插入件与相邻的支架接合并且具有与支架的顶表面具有相同的曲率半径的圆周表面。

6. 发明申请

US20060184507A1 Dynamically configurable lists for including multiple content types 失效
标题翻译：用于包含多种内容类型的动态配置列表
公开(公告)号：US20060184507A1
公开(公告)日：2006-08-17
申请号：US11058096
申请日：2005-02-14
申请人： Robert Lefferts , Hai Liu , Steven Rayson , Andrew Watson
发明人： Robert Lefferts , Hai Liu , Steven Rayson , Andrew Watson
IPC分类号： G06F7/00
CPC分类号： G06F17/30775 , G06F17/30274 , G06F17/30884 , G06Q10/0631
摘要： A dynamically configurable list management system that supports list elements of multiple content types is presented. Each list element is associated with an element type via an element type identifier. The element type identifier uniquely identifies the element type to the list management system. Each property associated with each element type is included in the list. Each property is identified by a unique property identifier. When adding a list element of a new element type to an existing list that does not include any elements of the new element type, the list management system identifies every property associated with the new element type. For each property associated with the new element type, the list management system determines which properties are not already included in the list, and adds those properties that are not already including to the list.
摘要翻译：介绍了支持多种内容类型的列表元素的动态配置列表管理系统。每个列表元素通过元素类型标识符与元素类型相关联。元素类型标识符唯一地标识列表管理系统的元素类型。与每个元素类型相关联的每个属性都包含在列表中。每个属性都由唯一的属性标识符标识。当将新元素类型的列表元素添加到不包含新元素类型的任何元素的现有列表时，列表管理系统将识别与新元素类型相关联的每个属性。对于与新元素类型相关联的每个属性，列表管理系统确定哪些属性尚未包括在列表中，并将尚未包含的属性添加到列表中。

7. 发明申请

US20070179535A1 Apparatus for use in the prophylaxis or treatment of tissue 有权
标题翻译：用于预防或治疗组织的装置
公开(公告)号：US20070179535A1
公开(公告)日：2007-08-02
申请号：US11525204
申请日：2006-09-22
申请人： Anthony Morrissey , Declan Soden , Gerald O'Sullivan , Christopher Collins , Colum Dunne , John Piggott , Denton Prior , Andrew Watson , Peter McGeehin
发明人： Anthony Morrissey , Declan Soden , Gerald O'Sullivan , Christopher Collins , Colum Dunne , John Piggott , Denton Prior , Andrew Watson , Peter McGeehin
IPC分类号： A61N1/00 , A61B18/18 , A61N1/30 , A61B18/04 , A61N5/06
CPC分类号： C12M35/02 , A61B18/1477 , A61B18/1492 , A61B2018/0016 , A61B2018/00291 , A61B2018/00482 , A61B2018/00494 , A61B2018/1425 , A61B2018/143 , A61B2218/002 , A61N1/0424 , A61N1/0476 , A61N1/327 , A61N5/0601 , A61N5/062
摘要： Apparatus (20) for carrying out a prophylactic or treatment procedure on tissue comprises a device (21) having a chamber (22) and at least one active element such as an electrode (23) within the chamber (22). The chamber (22) has an opening (26) through which tissue is drawn into the chamber (22). Means for drawing the tissue into the chamber may comprise a vacuum lumen with vacuum orifices (25) in the chamber (22). Treatment such as electroporation may be applied to tissue in the chamber (22).
摘要翻译：用于在组织上执行预防或治疗过程的装置（20）包括在腔室（22）内具有腔室（22）和至少一个有源元件（例如电极（23））的装置（21）。腔室（22）具有一个开口（26），组织被吸入腔室（22）中。用于将组织拉入腔室的装置可以包括在腔室（22）中具有真空孔（25）的真空腔。诸如电穿孔的治疗可以施加到腔室（22）中的组织。

8. 发明授权

US06212382B1 Method for handover in multicellular environment 失效
标题翻译：多细胞环境切换方法
公开(公告)号：US06212382B1
公开(公告)日：2001-04-03
申请号：US08817043
申请日：1997-07-14
申请人： Andrew Watson , Jonathan Hopkinson
发明人： Andrew Watson , Jonathan Hopkinson
IPC分类号： H04Q708
CPC分类号： H04W36/04
摘要： A method of performing a handover as shown in FIGS. 2-3 for a mobile station in a multicellular environment including the steps of determining to handover from one of the plurality of microcells to the macrocell, performing handover from the one of the plurality of microcells to the macrocell; and sending a false neighbor list to the mobile station.
摘要翻译：一种执行如图1和2所示的切换的方法。 2-3，用于在多小区环境中的移动站，包括确定从多个微小区之一切换到宏小区的步骤，执行从多个微小区之一到宏小区的切换; 并向移动台发送假邻居列表。

9. 发明申请

US20130225418A1 LABELING AND SAMPLE PREPARATION FOR SEQUENCING 有权
标题翻译：用于测序的标签和样品制备
公开(公告)号：US20130225418A1
公开(公告)日：2013-08-29
申请号：US13774437
申请日：2013-02-22
申请人： Andrew Watson
发明人： Andrew Watson
IPC分类号： G01N1/30
CPC分类号： G01N1/30 , C12Q1/6806 , C12Q1/6869 , C12Q2531/113 , C12Q2563/131 , C12Q2563/159 , C12Q2563/179 , C12Q2525/191 , C12Q2535/122 , C12Q2537/159 , C12Q2563/149 , C12Q2565/629
摘要： The invention provides methods for sequencing and sample preparation for sequencing and amplification.
摘要翻译：本发明提供了用于测序和扩增的测序和样品制备的方法。

10. 发明申请

US20130210659A1 MOLECULAR DIAGNOSTIC SCREENING ASSAY 审中-公开
公开(公告)号：US20130210659A1
公开(公告)日：2013-08-15
申请号：US13764459
申请日：2013-02-11
申请人： Andrew Watson , Darren Roy Link , Jeffrey Charles Olson , Michael Samuels
发明人： Andrew Watson , Darren Roy Link , Jeffrey Charles Olson , Michael Samuels
IPC分类号： C12N15/10 , C12Q1/68
CPC分类号： C12N15/1072 , C12Q1/6827 , C12Q1/6844 , C12Q1/6883 , C12Q1/6886 , C12Q2600/156 , C12Q2525/155 , C12Q2525/161 , C12Q2563/159 , C12Q2563/179 , C12Q2565/629 , C12Q2521/319 , C12Q2521/501 , C12Q2545/101
摘要： The invention generally relates to method for screening for a condition in a subject. In certain embodiments, methods of the invention involve obtaining a pool of nucleic acids from a sample, incubating the nucleic acids with first and second sets of binders, in which the first set binds uniquely to different regions of a target nucleic acid in the pool, the second set binds uniquely to different regions of a reference nucleic acid in the pool, and the first and second sets include different detectable labels, removing unbound binders, detecting the labels, and screening for a condition based upon results of the detecting step.

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