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1. 发明授权

US09557398B2 Cooperative pulses 有权
标题翻译：合作脉冲
公开(公告)号：US09557398B2
公开(公告)日：2017-01-31
申请号：US13704994
申请日：2011-06-20
申请人： Steffen J. Glaser , Michael Braun
发明人： Steffen J. Glaser , Michael Braun
IPC分类号： G01R33/58 , G06F17/11 , G01N24/08 , G01R33/44 , G01R33/46 , G01R33/465
CPC分类号： G01R33/583 , G01N24/08 , G01R33/441 , G01R33/46 , G01R33/4616 , G01R33/465 , G06F17/11
摘要： A method is proposed for the simultaneous optimization of an arbitrary number of electromagnetic pulses, which act in a cooperative way, or mutually compensate each other's errors. The method generally relates to pulses which can have improved properties when cooperating with each other compared to single pulses. In experiments with several scans, undesired signal contributions can be suppressed by COOP pulses, which complements and generalizes the concept of phase cycling. COOP pulses can also be used in individual scans. COOP pulses can be optimized efficiently with the aid of an extended version of the optimal-control-theory-based gradient ascent pulse engineering (GRAPE) algorithm. The advantage of the COOP pulse method is demonstrated theoretically and experimentally for broadband and band-selective excitation and saturation pulses.
摘要翻译：提出了一种以协同方式同时优化任意数量的电磁脉冲或相互补偿彼此误差的方法。该方法通常涉及与单个脉冲相比相互配合时具有改进特性的脉冲。在进行几次扫描的实验中，可以通过COOP脉冲抑制不期望的信号贡献，这补充并概括了相位循环的概念。 COOP脉冲也可用于单个扫描。 COOP脉冲可以借助于基于最优控制理论的梯度上升脉冲工程（GRAPE）算法的扩展版本来有效优化。 COOP脉冲方法的优点在理论和实验上用于宽带和频带选择性激励和饱和脉冲。

2. 发明申请

US20130090884A1 Cooperative Pulses 有权
标题翻译：合作脉冲
公开(公告)号：US20130090884A1
公开(公告)日：2013-04-11
申请号：US13704994
申请日：2011-06-20
申请人： Steffen J. Glaser , Michael Braun
发明人： Steffen J. Glaser , Michael Braun
IPC分类号： G01R33/58 , G06F17/11
CPC分类号： G01R33/583 , G01N24/08 , G01R33/441 , G01R33/46 , G01R33/4616 , G01R33/465 , G06F17/11
摘要： A method is proposed for the simultaneous optimization of an arbitrary number of electromagnetic pulses, which act in a cooperative way, or mutually compensate each other's errors. The method generally relates to pulses which can have improved properties when cooperating with each other compared to single pulses. In experiments with several scans, undesired signal contributions can be suppressed by COOP pulses, which complements and generalizes the concept of phase cycling. COOP pulses can also be used in individual scans. COOP pulses can be optimized efficiently with the aid of an extended version of the optimal-control-theory-based gradient ascent pulse engineering (GRAPE) algorithm. The advantage of the COOP pulse method is demonstrated theoretically and experimentally for broadband and band-selective excitation and saturation pulses.
摘要翻译：提出了一种以协同方式同时优化任意数量的电磁脉冲或相互补偿彼此误差的方法。该方法通常涉及与单个脉冲相比相互配合时具有改进特性的脉冲。在进行几次扫描的实验中，可以通过COOP脉冲抑制不期望的信号贡献，这补充并概括了相位循环的概念。 COOP脉冲也可用于单个扫描。 COOP脉冲可以借助于基于最优控制理论的梯度上升脉冲工程（GRAPE）算法的扩展版本来有效优化。 COOP脉冲方法的优点在理论和实验上用于宽带和频带选择性激励和饱和脉冲。

3. 发明授权

US09096825B2 7 α-hydroxysteroid dehydrogenase knockout mutants and use therefor 有权
标题翻译： 7α-羟基类固醇脱氢酶敲除突变体并用于此
公开(公告)号：US09096825B2
公开(公告)日：2015-08-04
申请号：US13699239
申请日：2011-05-27
申请人： Rolf Schmid , Michael Braun , Luo Liu , Arno Aigner , Dirk Weuster-Botz
发明人： Rolf Schmid , Michael Braun , Luo Liu , Arno Aigner , Dirk Weuster-Botz
IPC分类号： C12P33/00 , C12N9/04 , C12N1/20 , C12N15/00 , C12N15/87 , C07K14/245 , C12P33/06
CPC分类号： C12N9/0006 , C07K14/245 , C12P33/00 , C12P33/06 , C12Y101/01159
摘要： The invention relates to 12 α-hydroxysteroid dehydrogenases, nucleic acid sequences coding for the same, expression cassettes and vectors, recombinant microorganisms containing the corresponding coding nucleic acid sequences, a method for producing said 12 α-hydroxysteroid dehydrogenases, a method for enzymatic oxidation of 12 α-hydroxysteroids using said enzyme, a method for enzymatic reduction of 12-ketosteroids using said enzyme, a method for qualitative or quantitative determination of 12-ketosteroids and/or 12α-hydroxysteroids using said 12α-hydroxysteroid dehydrogenases and a method for production of ursodesoxycholic acid, comprising the enzyme-catalyzed cholic acid oxidation using said 12 α-hydroxysteroid dehydrogenases.
摘要翻译：本发明涉及12种α-羟基类固醇脱氢酶，编码相同的核酸序列，表达盒和载体，含有相应的编码核酸序列的重组微生物，所述12种α-羟基类固醇脱氢酶的制备方法，使用所述酶的12种α-羟基类固醇，使用所述酶酶促还原12-酮类固醇的方法，使用所述12α-羟基类固醇脱氢酶定性或定量测定12-酮类和/或12α-羟基类固醇的方法及其制备方法熊去氧胆酸，其包含使用所述12α-羟基类固醇脱氢酶的酶催化的胆酸氧化。

4. 发明申请

US20130326639A1 VIRTUAL MACHINE FOR PROCESSING MEDICAL DATA 有权
标题翻译：用于处理医疗数据的虚拟机
公开(公告)号：US20130326639A1
公开(公告)日：2013-12-05
申请号：US14000296
申请日：2011-03-29
申请人： Claudia Droste , Klaus Breitschaft , Michael Braun , Henrik Wist
发明人： Claudia Droste , Klaus Breitschaft , Michael Braun , Henrik Wist
IPC分类号： G06F21/62
CPC分类号： G06F21/6245 , G06F21/55
摘要： The present invention relates to a virtual machine (VM) for processing digital data, in particular medical data, by executing a digital data processing application program, in particular a medical data processing application program (MeDPAP), the virtual machine (VM) being a simulation of a computer, a) the virtual machine (VM) comprising a volatile memory (ViMStor) configured to comprise a storage space for temporary data (TEMP) for temporarily storing the digital data; b) the virtual machine (VM) being configured to be accessed by any virtual machine user activated on a virtual machine user list, wherein any activated maintenance virtual machine user is denied any permission regarding the storage space for temporary data (TEMP), wherein denying any permissions is performed by logging into the virtual machine (VM) as an administrator and setting corresponding options; c) wherein any administrator has been deactivated on the virtual machine user list, wherein deactivating any administrator has been performed by logging into the virtual machine (VM) as an administrator and setting corresponding options for each administrator in the virtual machine user list; d) wherein the virtual machine (VM) is in a state in which the administrator has been logged off after deactivating the administrator on the virtual machine user list.
摘要翻译：本发明涉及通过执行数字数据处理应用程序，特别是医疗数据处理应用程序（MeDPAP）来处理数字数据，特别是医疗数据的虚拟机（VM），虚拟机（VM）是计算机的仿真，a）包括易失性存储器（ViMStor）的虚拟机（VM），其被配置为包括用于临时存储数字数据的临时数据（TEMP）的存储空间; b）虚拟机（VM）被配置为由在虚拟机用户列表上激活的任何虚拟机用户访问，其中任何激活的维护虚拟机用户被拒绝关于临时数据（TEMP）的存储空间的任何许可，其中拒绝通过以管理员身份登录到虚拟机（VM）并设置相应的选项来执行任何权限; c）其中任何管理员已经在虚拟机用户列表上被停用，其中已经通过以管理员身份登录到虚拟机（VM）并且为虚拟机用户列表中的每个管理员设置相应的选项来去激活任何管理员; d）其中虚拟机（VM）处于在虚拟机用户列表上停用管理员之后管理员已经注销的状态。

5. 发明申请

US20130185175A1 USE OF USER-GENERATED CONTENT TO RANK PRODUCTS 审中-公开
标题翻译：用户生成的内容使用产品
公开(公告)号：US20130185175A1
公开(公告)日：2013-07-18
申请号：US13822957
申请日：2011-09-13
申请人： Adam Roozen , Michael Braun
发明人： Adam Roozen , Michael Braun
IPC分类号： G06Q30/06
CPC分类号： G06Q30/0629 , G06Q30/02
摘要： Product scores are generated for products. The product scores for the products are based on amounts of user-generated content (UGC) mentioning the products and based on how favorable the UGC is toward the products. A product comparison interface is provided to a consumer. The product comparison interface comprises product elements associated with at least some of the products. Each of the product elements comprises information about a different one of the products. The product comparison interface provides information about the product scores for the products associated with the product elements.
摘要翻译：为产品生成产品分数。产品的产品分数是根据用户生成内容（UGC）提到的产品数量，并根据教资会对产品的有利程度。向消费者提供产品比较界面。产品比较界面包括与至少一些产品相关联的产品元件。每个产品元素包括关于不同产品之一的信息。产品比较界面提供与产品元素相关的产品的产品分数信息。

6. 发明授权

US08369514B2 Method for the secure determination of data 失效
标题翻译：数据安全确定方法
公开(公告)号：US08369514B2
公开(公告)日：2013-02-05
申请号：US12294806
申请日：2006-12-19
申请人： Michael Braun , Anton Kargl , Bernd Meyer , Stefan Pyka
发明人： Michael Braun , Anton Kargl , Bernd Meyer , Stefan Pyka
IPC分类号： H04L9/00
CPC分类号： H04L9/003 , G06F7/725 , G06F2207/7266 , H04L9/3066 , H04L2209/12
摘要： The aim of the embodiments is to provide a method for the secure processing of data, in which security is increased in relation to side channel attacks. To achieve this, operation codes for commanding co-processors are determined, for example for the bit-dependent transposition of register contents. The solution exploits the fact that as a result of the technical configuration for the co-processor, a shift of register contents, for example from register A to register B cannot be differentiated from the exterior from a shift from register A to register C.
摘要翻译：实施例的目的是提供一种用于数据安全处理的方法，其中相对于侧向信道攻击增加了安全性。为了实现这一点，例如用于命令协处理器的操作代码被确定为寄存器内容的位相关转置。该解决方案利用了由于协处理器的技术配置的结果，寄存器内容（例如从寄存器A到寄存器B）的移位不能从外部从寄存器A到寄存器C的移位区分开。

7. 发明申请

US20120091109A1 Special heating floor mat device for heavy duty applications 审中-公开
标题翻译：特殊加热地板垫装置用于重型应用
公开(公告)号：US20120091109A1
公开(公告)日：2012-04-19
申请号：US13206801
申请日：2011-08-10
申请人： Randy Braun , Michael Braun
发明人： Randy Braun , Michael Braun
IPC分类号： H05B3/00
CPC分类号： H05B3/34 , H05B2203/014
摘要： A heating floor mat device for heavy duty vehicle applications comprised of an electrically heat able floor mat with a non-slip surface; at least one hold down component with features to enable the mat to be safely and removably secured to a floor board; electrical conductors for the resistance heating in the mat and for connecting the mat to a power of a floor of a vehicle and connected to an on-board power source to enable controlled heat to be delivered to the floor board and to reduce icy and wet conditions in the compartment of the vehicle.
摘要翻译：一种用于重型车辆应用的加热地板垫装置，包括具有防滑表面的电热地板垫; 至少一个具有特征的压紧部件，以使垫可以安全地和可移除地固定在地板上; 电导体，用于垫中的电阻加热，并用于将垫连接到车辆地板的电力并连接到车载电源，以使受控的热量被输送到地板，并减少冰冷和潮湿的条件在车厢内。

8. 发明申请

US20100217227A1 METHOD AND APPARATUS FOR DELIVERING OXYGEN AND/OR OTHER GASES AND/OR PHARMACOLOGICAL AGENTS TO TISSUE AND MEDICAL WIRE FOR USE WITHIN THE BODY 审中-公开
标题翻译：用于将氧气和/或其他气体和/或药物代谢物用于组织和医疗线用于体内的方法和装置
公开(公告)号：US20100217227A1
公开(公告)日：2010-08-26
申请号：US12578342
申请日：2009-10-13
申请人： Michael Braun , John S. Geis , Todd F. Davenport
发明人： Michael Braun , John S. Geis , Todd F. Davenport
IPC分类号： A61L31/16 , A61M25/00
CPC分类号： A61L27/56 , A61L29/146 , A61L31/146
摘要： A system comprising: a hollow tube having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end; at least a portion of the tube comprising a porous membrane; and a gas-rich perfluorocarbon solution incorporated in the porous membrane; wherein the porous membrane has a porosity in the range of 0.001-200 microns, in order that: (i) the gas-rich perfluorocarbon solution is effectively incorporated into the porous membrane; and (ii) when the porous membrane is positioned in blood, the gas-rich perfluorocarbon solution elutes out of the porous membrane, in aggregations small enough to prevent the creation of embolisms in the blood, with the elution of the gas-rich perfluorocarbon solution into the blood varying between minutes and several hours, depending on the temperature and the hemodynamics of the blood.A novel medical wire is also disclosed herein.
摘要翻译：一种系统，包括：中空管，其具有远端，近端和在远端和近端之间延伸的内腔; 所述管的至少一部分包括多孔膜; 和掺入多孔膜中的富含气体的全氟化碳溶液; 其中所述多孔膜的孔隙率在0.001-200微米的范围内，以便：（i）富气体全氟化碳溶液有效地并入多孔膜中; 和（ii）当多孔膜位于血液中时，富含气体的全氟化碳溶液以足够小的聚集体从多孔膜中洗脱出来，以防止在血液中产生栓塞，同时溶解富含气体的全氟化碳溶液根据血液的温度和血液动力学，血液在几分钟到几个小时之间变化。本文还公开了一种新颖的医用电线。

9. 发明申请

US20100172490A1 METHOD FOR THE SECURE DETERMINATION OF DATA 失效
标题翻译：数据的安全确定方法
公开(公告)号：US20100172490A1
公开(公告)日：2010-07-08
申请号：US12294806
申请日：2006-12-19
申请人： Michael Braun , Anton Kargl , Bernd Meyer , Stefan Pyka
发明人： Michael Braun , Anton Kargl , Bernd Meyer , Stefan Pyka
IPC分类号： H04L9/28
CPC分类号： H04L9/003 , G06F7/725 , G06F2207/7266 , H04L9/3066 , H04L2209/12
摘要： The aim of the embodiments is to provide a method for the secure processing of data, in which security is increased in relation to side channel attacks. To achieve this, operation codes for commanding co-processors are determined, for example for the bit-dependent transposition of register contents. The solution exploits the fact that as a result of the technical configuration for the co-processor, a shift of register contents, for example from register A to register B cannot be differentiated from the exterior from a shift from register A to register C.
摘要翻译：实施例的目的是提供一种用于数据安全处理的方法，其中相对于侧向信道攻击增加了安全性。为了实现这一点，例如用于命令协处理器的操作代码被确定为寄存器内容的位相关转置。该解决方案利用了由于协处理器的技术配置的结果，寄存器内容（例如从寄存器A到寄存器B）的移位不能从外部从寄存器A到寄存器C的移位区分开。

10. 发明申请

US20090076449A1 COATING AND METHOD FOR APPLYING A COATING TO A MEDICAL INSTRUMENT, AND MEDICAL INSTRUMENT 审中-公开
标题翻译：医用仪器和医用仪器涂层及其涂敷方法
公开(公告)号：US20090076449A1
公开(公告)日：2009-03-19
申请号：US11884666
申请日：2006-02-15
申请人： John S. Geis , Michael Braun , Adalbert Kovacs , Gerhard K. Wolf
发明人： John S. Geis , Michael Braun , Adalbert Kovacs , Gerhard K. Wolf
IPC分类号： A61M29/00 , A61M25/00
CPC分类号： A61M25/0009 , A61B2017/00853 , A61M25/0045 , A61M25/10 , A61M2025/0057 , A61M2025/105 , A61M2025/1081
摘要： The invention relates to a cover (1) for a medical instrument (3), which is characterized in that the cover (1) is a generally pipe-shaped body and consists of one single tape (11) which extends generally helicoidally about the axis of the pipe-shaped body. The invention furthermore relates to a process for applying a cover (1) onto a medical instrument (3) as well as to a medical instrument (3) which is provided with a cover (1).
摘要翻译：本发明涉及一种用于医疗器械（3）的盖（1），其特征在于，所述盖（1）是大致管状的主体，并且由一个单独的带（11）构成，所述单个带的管状体。本发明还涉及将盖（1）施加到医疗器械（3）以及设置有盖（1）的医疗器械（3）的方法。

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