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1. 发明申请

US20070138207A1 Fluid dispensing device 有权
标题翻译：流体分配装置
公开(公告)号：US20070138207A1
公开(公告)日：2007-06-21
申请号：US10598464
申请日：2005-03-10
申请人： Stanley Bonney , Hugh Connell , Michael Davies , James Godfrey , Mark Hedley , Robert Tansley
发明人： Stanley Bonney , Hugh Connell , Michael Davies , James Godfrey , Mark Hedley , Robert Tansley
IPC分类号： B67D5/64
CPC分类号： B05B11/3059 , A61M11/08 , B05B11/0038 , B05B11/3052 , B05B11/3056
摘要： A fluid dispensing device for dispensing a fluid product having a dispensing outlet from which the fluid product is dispensable, a supply of the fluid product, a dispensing member mounted for movement in a dispensing direction along an axis X-X from a first position to a second position which causes a dose of the fluid product in the supply to be dispensed from the dispensing outlet and a finger-operable actuator member mounted for movement in an actuating direction which is generally transverse to the axis.
摘要翻译：一种流体分配装置，用于分配具有分配出口的流体产品，流体产品从该分配出口是可分配的，流体产品的供应;分配构件，其被安装成沿着轴线XX沿着分配方向从第一位置移动到第二位置这导致供应中的流体产品的剂量从分配出口分配，以及手指可操作的致动器构件，其安装成用于沿大致横向于轴线的致动方向运动。

2. 发明申请

US20070062525A1 Medicament dispenser 审中-公开
标题翻译：药剂分配器
公开(公告)号：US20070062525A1
公开(公告)日：2007-03-22
申请号：US10502405
申请日：2003-01-22
申请人： Stanley Bonney , Michael Davies
发明人： Stanley Bonney , Michael Davies
IPC分类号： A61M15/00 , B65D83/06
CPC分类号： A61M15/0045 , A61M15/0003 , A61M15/0043 , A61M15/005 , A61M15/0051 , A61M15/0055 , A61M15/0068 , A61M15/007 , A61M15/008 , A61M15/009 , A61M2202/064
摘要： There is provided a medicament dispenser for use in the delivery of a combination medicament product. The dispenser comprises first and second medicament containers for containing first and second medicament active component; and first and second release means for releasing respective dose portions of the first and second medicament active component from the first and second medicament containers. The first medicament active component is kept separate from the second medicament active component until the point of release thereof for delivery in combination. The first medicament active component is selected from the group consisting of salmeterol, formoterol and any salts or solvates thereof. The second medicament active component is selected from the group consisting of beclomethasone ester, fluticasone ester and any salts or solvates thereof.
摘要翻译：提供了用于递送组合药物产品的药物分配器。分配器包括用于容纳第一和第二药物活性组分的第一和第二药物容器; 以及用于从第一和第二药物容器释放第一和第二药物活性成分的各剂量部分的第一和第二释放装置。将第一药物活性成分与第二药物活性成分保持分离，直到其释放点为组合递送。第一药物活性成分选自沙美特罗，福莫特罗及其任何盐或溶剂化物。第二药物活性成分选自倍氯米松酯，氟替卡松酯及其任何盐或溶剂化物。

3. 发明申请

US20060084908A1 Device 有权
标题翻译：设备
公开(公告)号：US20060084908A1
公开(公告)日：2006-04-20
申请号：US10534383
申请日：2003-11-05
申请人： Stanley Bonney , Michael Davies , Paul Rand
发明人： Stanley Bonney , Michael Davies , Paul Rand
IPC分类号： A61N1/30
CPC分类号： A61M15/009 , A61M15/0026 , A61M15/0068 , A61M15/0076 , A61M15/0081 , A61M15/08
摘要： A drug delivery device for delivering to a patient a drug composition from a container which contains the drug composition where the container is adapted to be placed in a dispensing mode thereof on application of an actuating condition thereto is disclosed. The device includes a dispensing unit adapted to receive the container, the dispensing unit having an actuating mechanism operable to apply the actuating condition to the container and an outlet through which the drug composition is dispensable from the device, and a removable casing unit for the dispensing unit. The dispensing and casing units have securing features for releasably, fixedly securing the units together, and the dispensing unit is operable to apply the actuating condition to the container when fixedly secured to the casing unit and when independent from the casing unit.
摘要翻译：本发明公开了一种药物输送装置，用于向包含药物组合物的容器中的药物组合物递送药物组合物，其中容器适于在施加致动条件时将其置于其分配模式中。所述装置包括适于容纳所述容器的分配单元，所述分配单元具有可操作以将所述致动条件施加到所述容器的致动机构和所述药物组合物可从所述装置分配的出口以及用于所述分配的可移除的壳体单元单元。分配和套管单元具有用于可释放地，固定地将单元固定在一起的固定特征，并且分配单元可操作以在固定地固定到壳体单元时以及独立于壳体单元时将致动条件施加到容器。

4. 发明申请

US20060057201A1 Multicomponent pharmaceutical dosage form 审中-公开
标题翻译：多组分药物剂型
公开(公告)号：US20060057201A1
公开(公告)日：2006-03-16
申请号：US10519158
申请日：2003-07-24
申请人： Stanley Bonney , Adrian Brown , Michael Davies , Daniel Margetson , Wayne Matthews , Stephen McAllister , Paul Rand , Alan Wilson
发明人： Stanley Bonney , Adrian Brown , Michael Davies , Daniel Margetson , Wayne Matthews , Stephen McAllister , Paul Rand , Alan Wilson
IPC分类号： A61K9/24
CPC分类号： A61J3/071 , A61K9/2072 , A61K9/4808
摘要： A multi-component pharmaceutical dosage form suitable for retaining drug substance can be released to provide a controlled drug release profile in the gastro intestinal environment, characterized by a body e.g. comprising a delayed release polymeric material such as Eudragit 4135F, the body having at least one cavity said cavity having a mouth opening and a film means e.g. comprising an immediate release polymeric material e.g. Eudragit E100 or a blend thereof, connected to the body and closing the mouth opening.
摘要翻译：可以释放适合于保留药物的多组分药物剂型，以在胃肠环境中提供受控的药物释放曲线，其特征在于身体例如。包括延迟释放聚合材料，例如Eudragit 4135F，所述本体具有至少一个腔，所述腔具有开口和膜装置，例如，包括立即释放的聚合材料，例如 Eudragit E100或其混合物，连接到身体并关闭开口。

5. 发明申请

US20050251289A1 Medicament dispenser 审中-公开
公开(公告)号：US20050251289A1
公开(公告)日：2005-11-10
申请号：US10522319
申请日：2003-07-23
申请人： Stanley Bonney , Michael Davies
发明人： Stanley Bonney , Michael Davies
IPC分类号： A61K45/00 , A61K31/137 , A61K31/167 , A61K31/56 , A61K31/573 , A61K31/58 , A61M15/00 , A61P11/08 , A61P29/00 , G06F17/00 , G07F11/00 , G06F17/60
CPC分类号： A61M15/00 , A61M15/0003 , A61M15/0071 , A61M15/008 , A61M15/0083 , A61M2205/52 , G06Q50/24
摘要： A medicament dispenser device for use in the delivery of a combination medicament product is disclosed. The device includes a first medicament container for containing a first medicament component; a first release means for releasing the contents of the first medicament container; at least one further medicament container for containing at least one further medicament component; and at least one further release means for releasing the contents of each said at least one further medicament container. The first medicament component is kept separate from the at least one further medicament component until the point of release thereof for delivery in combination. The dispenser device can additionally include at least one actuation indicator associated with the first medicament container and the at least one further medicament container.

6. 发明申请

US20050154491A1 Medicament dispenser 有权
标题翻译：药剂分配器
公开(公告)号：US20050154491A1
公开(公告)日：2005-07-14
申请号：US10502519
申请日：2003-01-22
申请人： Gregor Anderson , Stanley Bonney , Michael Davies , Daniel Thomas Lintell , Alan Wilson
发明人： Gregor Anderson , Stanley Bonney , Michael Davies , Daniel Thomas Lintell , Alan Wilson
IPC分类号： A61J7/02 , A61M15/00 , G06F17/00
CPC分类号： A61M15/0045 , A61M15/00 , A61M15/0003 , A61M15/0043 , A61M15/0051 , A61M15/0055 , A61M15/0068 , A61M15/0078 , A61M15/008 , A61M2016/0021 , A61M2202/064
摘要： There is provided a medicament dispenser for use with plural elongate form medicament carriers, each having multiple distinct medicament dose portions carried thereby, the dispenser having a dispensing mechanism for dispensing the distinct medicament dose portions carried by each of the plural medicament carriers. The mechanism comprises a receiving station for receiving each of the plural medicament carriers; a release for releasing a distinct medicament dose portion from each of the plural medicament carriers on receipt thereof by the receiving station; an outlet, positioned to be in communication with the distinct medicament dose portions releasable by said a release; and an indexer for individually indexing the distinct medicament dose portions of each of the plural medicament carriers.
摘要翻译：提供了一种用于多个细长形式药物载体的药物分配器，每个细长形式药物载体具有由其携带的多个不同的药物剂量部分，分配器具有用于分配由多个药物载体中的每一个承载的不同药物剂量部分的分配机构。该机构包括：接收站，用于接收多个药物载体中的每一个; 用于从接收站接收多个药物载体中的每一个释放不同药物剂量部分的释放物; 出口，定位成与通过所述释放可释放的不同药物剂量部分连通; 以及用于分别分配多个药物载体中的每一个的不同药物剂量部分的分度器。

7. 发明申请

US20050274378A1 Medicament dispenser 审中-公开
标题翻译：药剂分配器
公开(公告)号：US20050274378A1
公开(公告)日：2005-12-15
申请号：US10523066
申请日：2003-07-23
申请人： Stanley Bonney , Michael Davies
发明人： Stanley Bonney , Michael Davies
IPC分类号： A61M13/00 , A61M11/00 , A61M11/06 , A61M15/00 , A61M15/08 , A61M16/00
CPC分类号： A61M15/0086 , A61M11/005 , A61M11/06 , A61M15/0003 , A61M15/0026 , A61M15/0028 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0051 , A61M15/0055 , A61M15/0065 , A61M15/0075 , A61M15/008 , A61M15/0083 , A61M15/0085 , A61M15/009 , A61M15/0093 , A61M15/0096 , A61M15/08 , A61M2016/0021 , A61M2202/064 , A61M2205/3546 , A61M2205/3576 , A61M2205/505 , A61M2205/581 , A61M2205/80 , A61M2205/8206 , A61M2205/825 , A61M2205/8281 , A61M2205/8293 , A61M2206/16
摘要： A unitary dispensing device for use in the delivery of a first medicament and at least one further medicament. The device comprises a first medicament dispenser for the delivery of the first medicament and at least one further medicament dispenser for the delivery of the at least one further medicament. The first medicament dispenser and the at least one further medicament dispenser enable the first and the at least one further medicament to be kept separate until the point of delivery. The first medicament dispenser is different in type to the at least one further medicament dispenser.
摘要翻译：用于递送第一药物和至少一种其它药物的单一分配装置。该装置包括用于递送第一药物的第一药物分配器和用于递送至少一种其它药物的至少一个另外的药物分配器。第一药物分配器和至少一个另外的药物分配器使得第一和至少一个其它药物保持分开直到输送点。第一药剂分配器的类型与至少一个另外的药物分配器不同。

8. 发明申请

US20050268909A1 Medicament dispenser 审中-公开
标题翻译：药剂分配器
公开(公告)号：US20050268909A1
公开(公告)日：2005-12-08
申请号：US10523121
申请日：2003-07-23
申请人： Stanley Bonney , Michael Davies
发明人： Stanley Bonney , Michael Davies
IPC分类号： A61M13/00 , A61M11/06 , A61M15/00 , A61M16/00
CPC分类号： A61M15/0028 , A61M11/005 , A61M11/06 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0051 , A61M15/0055 , A61M15/0065 , A61M15/0066 , A61M15/008 , A61M15/0083 , A61M15/0085 , A61M15/0086 , A61M15/009 , A61M15/0096 , A61M2016/0021 , A61M2202/064 , A61M2205/3546 , A61M2205/3576 , A61M2205/505 , A61M2205/581 , A61M2205/80 , A61M2205/8206 , A61M2206/16
摘要： A medicament dispenser device for use in the delivery of a multi-component combination medicament product. The device comprises a first medicament container containing plural co-formulation compatible medicament components; first release means for releasing the contents of the first medicament container for delivery thereof; at least one further medicament container, each containing at least one co-formulation incompatible medicament component; and at least one further release means for releasing the contents of each at least one further medicament container for delivery thereof. The at least one co-formulation incompatible medicament component is kept separate from the plural co-formulation compatible components until the point of release thereof for delivery in combination.
摘要翻译：一种用于递送多组分组合药物产品的药物分配器装置。该装置包括含有多个共配方相容的药物成分的第一药物容器; 第一释放装置，用于释放用于输送第一药物容器的内容物; 至少一个另外的药物容器，每个药物容器含有至少一种共配方不相容的药物成分; 以及至少一个另外的释放装置，用于释放每个至少一个另外的药物容器的内容物用于输送。将至少一种共配方不相容的药物组分与多种共配方相容性组分保持分离，直至其释放点组合用于递送。

9. 发明申请

US20050268908A1 Medicament dispenser 审中-公开
标题翻译：药剂分配器
公开(公告)号：US20050268908A1
公开(公告)日：2005-12-08
申请号：US10522325
申请日：2003-07-23
申请人： Stanley Bonney , Michael Davies
发明人： Stanley Bonney , Michael Davies
IPC分类号： A61K45/06 , A61K31/137 , A61K31/14 , A61K31/57 , A61M11/00 , A61M11/08 , A61M15/00 , A61P11/00 , A61P11/06 , A61P11/08 , A61P31/04 , A61P43/00 , B05D7/14 , A61M16/00 , B65D83/06
CPC分类号： A61M15/0045 , A61M15/0003 , A61M15/0043 , A61M15/0051 , A61M15/0055 , A61M15/0071 , A61M15/0076 , A61M15/008 , A61M15/0081 , A61M15/0083 , A61M15/009
摘要： A medicament dispenser device for use in the delivery of a combination medicament product is disclosed. The device includes a first medicament container for containing a first medicament component; first release means for releasing the contents of the first medicament container; at least one further medicament container for containing at least one further medicament component; at least one further release means for releasing the contents of each the at least one further medicament container; and mixing means for promoting the mixing of the released contents of the first and at least one further medicament container. The first medicament component is kept separate from the at least one further medicament component until the point of release thereof for delivery in combination.
摘要翻译：公开了用于递送组合药物产品的药物分配器装置。该装置包括用于容纳第一药物组分的第一药物容器; 用于释放第一药物容器的内容物的第一释放装置; 至少一个另外的药物容器，用于容纳至少一种其它药物成分; 至少一个另外的释放装置，用于释放每个所述至少一个另外的药物容器的内容物; 以及用于促进第一和至少一个另外的药物容器的释放内容物的混合的混合装置。将第一药物组分与至少一种其它药物组分保持分离直到其释放点为组合递送。

10. 发明申请

US20070131717A1 Fluid dispensing device 有权
标题翻译：流体分配装置
公开(公告)号：US20070131717A1
公开(公告)日：2007-06-14
申请号：US10577977
申请日：2004-11-02
申请人： Michael Davies , Mark Hedley , Margot Jones
发明人： Michael Davies , Mark Hedley , Margot Jones
IPC分类号： B67D5/64
CPC分类号： A61M15/0001 , A61M15/009 , A61M15/08 , B05B11/0037 , B05B11/0038 , B05B11/3052 , B05B11/3056 , B05B11/3059 , B65D83/16 , B65D83/201 , B65D83/386
摘要： A fluid dispensing device for dispensing a fluid form medicament formulation having a viscosity of from 10 to 2000 mPa·s. is disclosed and comprises a housing and a fluid discharge device. The fluid discharge device is arranged to be actuated by one or more levers so as to apply a force to the fluid discharge device which is used to move a container forming part of the fluid discharge device along a longitudinal axis of the fluid discharge device to cause actuation of a pump forming part of the fluid discharge device. A pre-load means is used to prevent actuation of the pump until a pre-determined force is applied to each lever of sufficient magnitude to guarantee the production of a well developed efficient spray from the fluid dispensing device.
摘要翻译：一种用于分配粘度为10-2000mPa.s的流体形式药物制剂的流体分配装置。并且包括壳体和流体排出装置。流体排出装置被布置成由一个或多个杠杆致动，以便向流体排放装置施加力，所述流体排放装置用于沿着流体排放装置的纵向轴线移动形成流体排放装置的一部分的容器以使得形成流体排出装置的一部分的泵的致动。使用预加载装置来防止泵的致动，直到对每个杠杆施加足够大的预定力，以保证从流体分配装置产生良好的有效喷雾。

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