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1. 发明授权

US12138387B2 Inhaler system 有权
公开(公告)号：US12138387B2
公开(公告)日：2024-11-12
申请号：US17131154
申请日：2020-12-22
申请人： Norton (Waterford) Limited
发明人： Mark Milton-Edwards , Guilherme Safioti , Lena Granovsky , Michael Reich
IPC分类号： A61M15/00 , A61B5/00 , A61B5/08 , A61K31/138 , C07K16/24 , C07K16/28 , C07K16/42 , G16H20/10 , G16H20/13 , G16H50/30 , G16H50/70 , A61M11/00
CPC分类号： A61M15/009 , A61B5/0826 , A61B5/4848 , A61B5/7275 , A61K31/138 , A61M15/0001 , A61M15/0025 , A61M15/003 , A61M15/008 , A61M15/0091 , C07K16/244 , C07K16/247 , C07K16/2866 , C07K16/4291 , G16H20/10 , G16H20/13 , G16H50/30 , G16H50/70 , A61M11/00 , A61M15/0026 , A61M2202/064 , A61M2205/05 , A61M2205/18 , A61M2205/3327 , A61M2205/3331 , A61M2205/3358 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2230/30 , A61M2230/40 , C07K2317/21 , C07K2317/24 , C07K2317/52
摘要： Provided is a system for determining a probability of a respiratory disease exacerbation in a subject. The system comprises an inhaler arrangement for delivering a medicament to the subject. The medicament may be a rescue medicament and/or a maintenance medicament. The inhaler arrangement has a use-detection system configured to determine an inhalation performed by the subject using the inhaler arrangement. A sensor system is configured to measure a parameter relating to airflow during the inhalation. A user interface enables user-input of an indication of a status of the respiratory disease being experienced by the subject. A processor is configured to determine the probability of the respiratory disease exacerbation based on the recorded inhalation(s) from the use-detection system, the parameter(s) received from the sensor system, and the indication received from the user interface. Further provided is a method for determining the probability of a respiratory disease exacerbation in a subject.

2. 发明公开

US20240358662A1 COMPOSITIONS, METHODS AND SYSTEMS FOR AEROSOL DRUG DELIVERY 审中-公开
公开(公告)号：US20240358662A1
公开(公告)日：2024-10-31
申请号：US18577165
申请日：2022-07-08
申请人： ASTRAZENECA PHARMACEUTICALS LP
发明人： Vidya JOSHI , James ARCHBELL , Kellisa LACHACZ , Charina LAMPA , Lauren MELLO , Gertrude GUTIERREZ , David LECHUGA-BALLESTEROS , Penny TAN , Michael RIEBE
IPC分类号： A61K31/167 , A61K9/00 , A61K9/16 , A61K31/40 , A61K31/58 , A61K47/06 , A61M15/00
CPC分类号： A61K31/167 , A61K9/008 , A61K9/1617 , A61K31/40 , A61K31/58 , A61K47/06 , A61M15/0001
摘要： Compositions, methods, and systems are provided for pulmonary delivery of active agents via a metered dose inhaler. In some embodiments, the compositions comprise an HFO-1234ze (E) suspension medium, active agent particles, and suspending particles. The active agent particles may comprise one, two, three or four active agent(s) selected from a long-acting muscarinic antagonist (LAMA), a long-acting β2-agonists (LABA), a short-acting beta-agonists (SABA), an inhaled corticosteroid (ICS), and a non-corticosteroid anti-inflammatory agent.

3. 发明授权

US12115357B2 Integrated delivery device for continuous glucose sensor 有权
公开(公告)号：US12115357B2
公开(公告)日：2024-10-15
申请号：US17696198
申请日：2022-03-16
申请人： DexCom, Inc.
发明人： James H. Brauker , Mark A. Tapsak , Sean T. Saint , Apurv Ullas Kamath , Paul V. Neale , Peter C. Simpson , Michael Robert Mensinger , Dubravka Markovic
IPC分类号： A61M5/315 , A61B5/00 , A61B5/145 , A61B5/1486 , A61M5/172 , A61M11/00 , A61M15/00 , G16H10/40 , G16H20/17 , G16H40/63
CPC分类号： A61M5/31525 , A61B5/0002 , A61B5/14532 , A61B5/14865 , A61B5/4839 , A61M5/1723 , A61M11/00 , A61M15/0001 , G16H10/40 , G16H20/17 , G16H40/63 , A61B5/1486 , A61B2560/0443 , A61M2005/1726 , A61M2205/18 , A61M2205/3303 , A61M2205/502 , A61M2205/52 , A61M2230/201
摘要： Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.

4. 发明公开

US20240277948A1 ELECTRONIC MODULE FOR MEDICAL DEVICE 审中-公开
公开(公告)号：US20240277948A1
公开(公告)日：2024-08-22
申请号：US18645057
申请日：2024-04-24
申请人： Norton (Waterford) Limited
发明人： James Roche , Enrique Calderon Oliveras
IPC分类号： A61M15/00 , G16H20/13 , G16H40/63 , H05K1/18
CPC分类号： A61M15/0001 , G16H20/13 , G16H40/63 , H05K1/181 , A61M2205/8206 , H05K2201/10037 , H05K2201/10628
摘要： An electronic module for a medical device such as an inhaler is disclosed, the electronic module comprising a printed circuit board, and a damper configured to dampen energy transfer to and/or from a battery when a battery is connected to the electronic module and the electronic module is exposed to mechanical shock.

5. 发明授权

US11793945B2 Droplet delivery device with push ejection 有权
公开(公告)号：US11793945B2
公开(公告)日：2023-10-24
申请号：US17846902
申请日：2022-06-22
申请人： PNEUMA RESPIRATORY, INC.
发明人： Charles Eric Hunter , Michael Scoggin , Jeffrey Miller , Jose Salazar , Brian Beach , Caley Modlin , Matthew Culpepper , Jianqiang Li , Chengjie Li , Shi Bo Wang , Chao-Ping Lee , Gregory Rapp , Judson Sidney Clements
IPC分类号： A61M11/00 , A61M15/00
CPC分类号： A61M11/003 , A61M11/005 , A61M15/0001 , A61M15/002 , A61M15/0085 , A61M2206/11
摘要： A droplet delivery device includes a housing with a mouthpiece port or outlet from a nasal device for releasing fluid droplets, a fluid reservoir, and an ejector bracket having a membrane positioned between a mesh with a plurality of openings and a vibrating member that is coupled to an electronic transducer, such as an ultrasonic transducer. The transducer vibrates the vibrating member which causes the membrane to push fluid supplied by the reservoir through the mesh to generate droplets in an ejected stream released through the outlet.

6. 发明授权

US11779056B2 Atomizer 有权
公开(公告)号：US11779056B2
公开(公告)日：2023-10-10
申请号：US17012364
申请日：2020-09-04
申请人： SHENZHEN BUDDY TECHNOLOGY DEVELOPMENT CO., LTD.
发明人： Xiang Liu
IPC分类号： A24F40/95 , A61M15/00 , A24F40/46 , A24F40/53
CPC分类号： A24F40/95 , A24F40/46 , A24F40/53 , A61M15/0001 , A61M15/0086 , A61M2205/8206 , A61M2205/8237
摘要： An atomizer is provided. The atomizer includes a battery rod, including a rod body, a battery, and a first electrical connection part arranged on the rod body and exposed from the rod body, wherein an end of the rod body is disposed with a receiving part, and the first electrical connection part is located in the receiving part, an atomizing head, including a housing and a second electrical connection part arranged on the housing and exposed from the housing, and a mechanical switch, arranged on the rod body and exposed outside the rod body, wherein the mechanical switch is electrically connected between the battery and the first electrical connection part, and configured to turn on or turn off an electrical connection between the battery and the first electrical connection part; wherein the first electrical connection part is in contact with the second electrical connection part when the atomizing head is inserted into the receiving part, the electrical connection between the battery and the first electrical connection part is turned on when the atomizing head is inserted into the receiving part and the mechanical switch is triggered, and thereby an electrical connection between the first electrical connection part and the second electrical connection part is turned on to supply a power to the atomizing head through the battery. Using the mechanical switch to control the battery rod whether supply a power to the atomizing head or not can ensure the effectiveness of triggering power supply for a long time.

7. 发明授权

US11771851B2 Testing method for a dry powder inhaler 有权
公开(公告)号：US11771851B2
公开(公告)日：2023-10-03
申请号：US17337325
申请日：2021-06-02
申请人： NORTON (WATERFORD) LIMITED
发明人： Denis Henry O'Sullivan , Daniel R Buck
IPC分类号： A61M15/00 , A61M16/14 , G01N15/06 , G01N15/00
CPC分类号： A61M15/0008 , A61M15/0001 , A61M15/0086 , A61M15/0091 , A61M16/14 , G01N15/06 , A61M2202/064 , G01N2015/0046 , G01N2015/0693
摘要： The invention provides a method of testing an inhaler based on performing an optical analysis of a dry powder medicament plume discharged from the inhaler upon actuation. More particularly, embodiments of the invention comprise illuminating the dry powder plume with a source of electromagnetic radiation and capturing one or more images of a pattern of radiation reflected or diffracted by the illuminated plume. The images are subsequently processed to determine and/or analyse one or more geometric and/or dynamic characteristics of the plume.

8. 发明公开

US20230277782A1 VAPORIZER CATRIDGE AND AIRFLOW PATH THERETHROUGH 审中-公开
公开(公告)号：US20230277782A1
公开(公告)日：2023-09-07
申请号：US18163130
申请日：2023-02-01
申请人： RAI STRATEGIC HOLDINGS, INC.
发明人： Nathan Andrew Terry , Noah Mark Minskoff
IPC分类号： A61M15/00 , A61M11/04 , A61M15/06 , A24F40/44 , A24F40/46 , A24F40/485
CPC分类号： A61M15/0001 , A24F40/44 , A24F40/46 , A24F40/485 , A61M11/041 , A61M11/042 , A61M15/0025 , A61M15/0035 , A61M15/06 , A61M2016/0018 , A61M2205/0205 , A61M2205/0233 , A61M2205/13 , A61M2205/3592 , A61M2205/52 , A61M2205/59 , A61M2205/8206 , A61M2230/005 , A61M2230/65
摘要： A personal vapor inhaling unit is disclosed. An electronic flameless vapor inhaler unit that may simulate a cigarette has a cavity that receives a cartridge in the distal end of the inhaler unit. The cartridge brings a substance to be vaporized in contact with a wick. When the unit is activated, and the user provides suction, the substance to be vaporized is drawn out of the cartridge, through the wick, and is atomized by the wick into a cavity containing a heating element. The heating element vaporizes the atomized substance. The vapors then continue to be pulled by the user through a mouthpiece and mouthpiece cover where they may be inhaled.

9. 发明授权

US11744965B2 System for analyzing and controlling consumable media dosing information 有权
公开(公告)号：US11744965B2
公开(公告)日：2023-09-05
申请号：US16520148
申请日：2019-07-23
申请人： Wellness Insight Technologies, Inc.
发明人： Ramon Alarcon
IPC分类号： A61M15/06 , A61M15/00
CPC分类号： A61M15/06 , A61M15/0001 , A61M15/0065
摘要： A vaporizing article, comprises a vaporizer drive circuit; one or more memories configured to store a percentage of at least one constituent in an inhalation media, one or more compensation values for at least one compensation category for the at least one constituent, and instructions; and a control circuit comprising a processor coupled with the one or more memories configured to run the instructions, the instructions configured to cause the processor to: receive a dose target for a constituent; determine whether to perform compensation for an inhalation media dose in order to ensure the dose target is met; when compensation is to be performed, determine the properly compensated inhalation media dose based on an associated compensation value for the constituent; and control the vaporizer drive circuit so as to dispense a compensated dose of the inhalation media.

10. 发明公开

US20230154604A1 HUB DEVICE FOR A PORTABLE MEDICAL DEVICE 审中-公开
公开(公告)号：US20230154604A1
公开(公告)日：2023-05-18
申请号：US17915080
申请日：2021-04-21
申请人： SHL MEDICAL AG
发明人： Slobodan Stefanov
IPC分类号： G16H40/63 , A61M5/172 , A61M15/00
CPC分类号： G16H40/63 , A61M5/172 , A61M15/0001 , A61M2005/2006 , A61M2205/3561 , A61M2205/3584
摘要： A hub device configured to enable wireless communication between portable medical devices and an external device, where the hub device has a radio transceiver device configured to receive portable medical device data from each portable medical device and configured to transmit received portable medical device data to the external device, an energy storage unit configured to power the radio transceiver device, and an energy harvesting circuit configured to harvest radio frequency energy to charge the energy storage unit, wherein the hub device is configured to communicate with the portable medical devices using a protocol that for each portable medical device enables a unique portable medical device identifier to be included in the portable medical device data, and wherein the hub device has processing circuitry configured to establish a communications link with a portable medical device if the processing circuitry confirms recognition of the unique portable medical device identifier received from the portable medical device.

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