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1. 发明授权

US07597679B2 Safety system for an electrically driven medical delivery device and a computer-readable medium 有权
标题翻译：用于电驱动医疗输送装置和计算机可读介质的安全系统
公开(公告)号：US07597679B2
公开(公告)日：2009-10-06
申请号：US10397913
申请日：2003-03-26
申请人： Soren Kragh Jespersen , Jens Aage Munk , Jim Radmer , Jens Ulrik Poulsen , Lars Hofmann Christensen , Lars Peter Klitmose
发明人： Soren Kragh Jespersen , Jens Aage Munk , Jim Radmer , Jens Ulrik Poulsen , Lars Hofmann Christensen , Lars Peter Klitmose
IPC分类号： A61M31/00
CPC分类号： G05B9/02 , A61M5/168 , A61M5/172
摘要： This invention relates to a safety system for an electrically driven medical delivery device for delivering a dose of medication, wherein the safety system is configured for preventing delivery of an erroneous dose of the medicament and comprising detector means for registering mechanical movement, the system comprising at least two detector means (10, 11) for detecting a mechanical parameter and for emitting signals to control circuits (14, 15) configured for controlling the rower supply to driving means (12) for the delivery device. Further, this invention relates to a computer-readable medium comprising a program for controlling a delivery device etc. This allows providing a system that works very quickly, accurately and reliable as to preventing an erroneous dose of medication.
摘要翻译：本发明涉及一种用于输送一定剂量药物的电动医疗输送装置的安全系统，其中该安全系统构造成用于防止错误剂量的药物的递送并且包括用于对机械运动进行配准的检测器装置，该系统包括：至少两个用于检测机械参数并用于向控制电路（14,15）发射信号的检测器装置（10,11），所述控制电路被配置用于控制对于输送装置的驱动装置（12）的抽头供应。此外，本发明涉及包括用于控制递送装置等的程序的计算机可读介质。这允许提供非常快速，准确和可靠地工作以防止药物的错误剂量的系统。

2. 发明授权

US5957889A Displacement system for controlled infusion of a liquid 失效
标题翻译：用于控制液体输注的位移系统
公开(公告)号：US5957889A
公开(公告)日：1999-09-28
申请号：US615298
申请日：1996-08-29
申请人： Jens Ulrik Poulsen , Henrik Ljunggreen , Henning Munk Ejlersen , Jens Munk , Lars Peter Klitmose , Preben Broskov Nielsen , S.o slashed.ren Mikkelsen , Jens M.o slashed.ller-Jensen , Anders Heger
发明人： Jens Ulrik Poulsen , Henrik Ljunggreen , Henning Munk Ejlersen , Jens Munk , Lars Peter Klitmose , Preben Broskov Nielsen , S.o slashed.ren Mikkelsen , Jens M.o slashed.ller-Jensen , Anders Heger
IPC分类号： A61M5/145 , A61M37/00 , A61M5/315
CPC分类号： A61M5/14566 , B05C17/0113
摘要： In a displacement system for controlled infusion of a liquid from a cartridge comprising a tubular vessel (1), which is at a rear end closed by a piston (3) which may be forced by a piston rod (8) moving into the vessel (1) in the axial direction thereof to press out the liquid through an outlet (2) arranged at a front end of the vessel (1), the piston rod (8) is provided as a flexible incompressible construction which is by a piston rod guide (9) behind the rear end of the cartridge deflected away from the axis of this cartridge, preferably 180.degree.. The piston rod guide (9) has a guiding track comprising a curved part and linear parts at each end of the curved part ensuring that the piston rod is guided along a length (a) in the direction of the axis of the cartridge which length (a) is longer than the distance (b) between the two axes of the piston rod parts projecting from the piston rod guide. The guiding track is further elaborated to the very shape which the curved part of the piston rod will spontaneously adopt when its end portions are kept parallel.
摘要翻译： PCT No.PCT / DK94 / 00361 Sec。 371日期：1996年8月29日 102（e）日期1996年8月29日PCT 1994年9月27日PCT公布。公开号WO95 / 09021 日期1995年4月6日在用于从包括管状容器（1）的药筒受控输注液体的位移系统中，所述管状容器（1）的后端被可由活塞杆（8）迫使的活塞（3）封闭，沿着其轴向移动到容器（1）中以通过布置在容器（1）的前端的出口（2）将液体挤压出来，活塞杆（8）被设置为柔性不可压缩结构，其是通过活塞杆引导件（9）在盒的后端后面偏离该盒的轴线，优选地为180度。活塞杆引导件（9）具有引导轨道，该引导轨道包括弯曲部分和在弯曲部分的每个端部处的直线部分，确保活塞杆沿长度方向（a）沿长度方向（a）被引导， a）比从活塞杆引导件突出的活塞杆部件的两个轴线之间的距离（b）长。引导轨进一步细化为当其端部保持平行时活塞杆的弯曲部分将自动采用的形状。

3. 发明授权

US07803128B2 Needle insertion sensor 有权
标题翻译：针插入传感器
公开(公告)号：US07803128B2
公开(公告)日：2010-09-28
申请号：US11763024
申请日：2007-06-14
申请人： Lars Hofmann Christensen , Jens Ulrik Poulsen , Jan H. Simonsen
发明人： Lars Hofmann Christensen , Jens Ulrik Poulsen , Jan H. Simonsen
IPC分类号： A61M31/00
CPC分类号： A61B5/0404 , A61B5/14532
摘要： This invention relates to a doser comprising a syringe (2) with a needle (3) which extends beyond the doser (1), which comprises an engagement face (4) in the vicinity of the needle so that the engagement face rests against the surface of the tissue into which the needle is inserted. Detector means (5) are provided on said engagement face to sample signals on the skin of the patient. The invention further provides means (13) for receiving external information related to health monitoring of a patient. This provides a doser that may record heart rate, EKG, BGM and hypo-alarm administered medicine. The doser may further be arranged to calculate an appropriate dose of medication on the basis of a number of acquired inputs.
摘要翻译：本发明涉及一种配料器，其包括具有延伸超过定料器（1）的针（3）的注射器（2），其包括在针附近的接合面（4），使得接合面靠在表面的针被插入其中的组织。检测器装置（5）设置在所述接合面上以对患者的皮肤采样信号。本发明还提供了用于接收与患者的健康监测相关的外部信息的装置（13）。这提供了可以记录心率，EKG，BGM和低报警药物的加药器。可以进一步将加料器设置为基于所获取的输入的数量来计算适当剂量的药物。

4. 发明授权

US06656114B1 Method and a system for assisting a user in a medical self treatment, said self treatment comprising a plurality of actions 有权
标题翻译：方法和用于辅助用户进行医疗自我治疗的系统，所述自我治疗包括多个动作
公开(公告)号：US06656114B1
公开(公告)日：2003-12-02
申请号：US09462128
申请日：2000-10-30
申请人： Jens Ulrik Poulsen , Lars Hofmann Christensen , Søren Aasmul
发明人： Jens Ulrik Poulsen , Lars Hofmann Christensen , Søren Aasmul
IPC分类号： A61B500
CPC分类号： G06Q50/24 , A61B5/0002 , A61B5/14532 , A61B2560/0406 , A61B2560/0443 , A61B2562/0219 , A61M5/003 , A61M5/24 , A61M2205/505 , A61M2205/52 , G06F19/00 , G06F19/325 , G06F19/3468 , G06F19/3475 , G06F19/3481 , G16H10/60 , G16H50/50 , Y10S128/92 , Y10S128/921
摘要： A method of self treating a disease, such as diabetes, includes collecting in one or more databases data representing values of parameters that related to the self treatment. The data is processed to provide a plurality of alternate choices between two or more actions that may be taken and a corresponding value for each action is calculated. A computerized system may be employed to perform the above method and the system may include a computer readable medium for executing the method.
摘要翻译：自我治疗疾病如糖尿病的方法包括在一个或多个数据库中收集表示与自身治疗相关的参数值的数据。处理数据以在可以采取的两个或多个动作之间提供多个替代选择，并计算每个动作的相应值。可以采用计算机化系统来执行上述方法，并且系统可以包括用于执行该方法的计算机可读介质。

5. 发明授权

US06585699B2 Drug delivery device provided with a one-way mechanism 有权
公开(公告)号：US06585699B2
公开(公告)日：2003-07-01
申请号：US09822162
申请日：2001-03-30
申请人： Henrik Ljunggreen , Jens Ulrik Poulsen , Soren Aasmul , Lars Hofmann Christensen , Jens Moller-Jensen , Peter Moller-Jensen
发明人： Henrik Ljunggreen , Jens Ulrik Poulsen , Soren Aasmul , Lars Hofmann Christensen , Jens Moller-Jensen , Peter Moller-Jensen
IPC分类号： A61M528
CPC分类号： A61M5/31511 , A61M5/31501 , A61M5/31543 , A61M5/3156 , A61M5/31585 , A61M5/31593 , A61M2005/31518 , A61M2005/31588
摘要： A drug delivery device comprising a housing (1) with a drug container (2) being provided with delivering means comprising a piston (5) for expelling a drug (4) from the drug container (2). The housing (1) further comprising a displaceable piston rod (6) abutting the piston (5) of the drug container (2) and rotating means being in engagement with the piston rod (6), said rotating means being provided with a one-way mechanism. The one-way mechanism comprises a helical spring (12) wound tightly around an axle (11), one end of said helical spring (12) being fixed in relation to the housing (1), the other end of the helical spring (12) being in a free state.

6. 发明授权

US06340357B1 Dose setting device 失效
标题翻译：剂量设定装置
公开(公告)号：US06340357B1
公开(公告)日：2002-01-22
申请号：US09360263
申请日：1999-07-26
申请人： Jens Ulrik Poulsen , Henrik Ljunggreen , Lars Hofmann Christensen
发明人： Jens Ulrik Poulsen , Henrik Ljunggreen , Lars Hofmann Christensen
IPC分类号： A61M500
CPC分类号： A61M5/20 , A61M5/14546 , A61M5/14566 , A61M5/31525 , A61M5/31546 , A61M2005/31588 , A61M2205/581 , G06F19/00 , Y10S128/01
摘要： The present invention relates to a drug delivery device wherein a dose to be apportioned from a cartridge is set by changing the relative position of co-operating dose setting elements (3, 5) and is injected by pressing a button (5) until this button abuts a stop (6). By operation of count up (7) or count down (8) buttons the dose is set and read into an electronic circuit (9) comprising a microprocessor and the dose setting movement of the dose setting elements relative to each other is performed by a motor (11) controlled by the circuit in accordance with the read in dose. The set dose is shown on a display (10). The motor (11) is further controlled to perform certain movements of the piston rod (3) so as retraction of this rod when a cartridge (1) is going to be changed an advancing of the piston rod to abutment with the piston (2) after the cartridge has been changed and further to advance this piston to expel air from the cartridge.
摘要翻译：本发明涉及一种药物输送装置，其中通过改变配合剂量设定元件（3,5）的相对位置来设定从药筒分配的剂量，并且通过按压按钮（5）注射直到该按钮停靠（6）。通过计数（7）或倒计时（8）按钮的操作，剂量被设置并读入包括微处理器的电子电路（9），并且剂量设定元件相对于彼此的剂量设定运动由电动机（11）由电路按照读取的剂量控制。设定的剂量显示在显示器（10）上。电动机（11）被进一步控制以执行活塞杆（3）的某些运动，以便当筒（1）将改变活塞杆的前进以与活塞（2）邻接时，该杆的缩回，在盒被改变之后，并且进一步推进该活塞以从盒中排出空气。

7. 发明授权

US07282029B1 Method and a system for assisting a user in a medical self treatment, said self treatment comprising a plurality of actions 有权
标题翻译：方法和用于辅助用户进行医疗自我治疗的系统，所述自我治疗包括多个动作
公开(公告)号：US07282029B1
公开(公告)日：2007-10-16
申请号：US10663463
申请日：2003-09-16
申请人： Jens Ulrik Poulsen , Lars Hofmann Christensen , Soren Aasmul
发明人： Jens Ulrik Poulsen , Lars Hofmann Christensen , Soren Aasmul
IPC分类号： A61B5/00
CPC分类号： G06Q50/24 , A61B5/0002 , A61B5/14532 , A61B2560/0406 , A61B2560/0443 , A61B2562/0219 , A61M5/003 , A61M5/24 , A61M2205/505 , A61M2205/52 , G06F19/00 , G06F19/325 , G06F19/3468 , G06F19/3475 , G06F19/3481 , G16H10/60 , G16H50/50 , Y10S128/92 , Y10S128/921
摘要： A method of self treating a disease, such as diabetes, includes collecting in one or more databases data representing values of parameters that related to the self treatment. The data is processed to provide a plurality of alternate choices between two or more actions that may be taken and a corresponding value for each action is calculated. A computerized system may be employed to perform the above method and the system may include a computer readable medium for executing the method.
摘要翻译：自我治疗疾病如糖尿病的方法包括在一个或多个数据库中收集表示与自身治疗相关的参数值的数据。处理数据以在可以采取的两个或多个动作之间提供多个替代选择，并计算每个动作的相应值。可以采用计算机化系统来执行上述方法，并且系统可以包括用于执行该方法的计算机可读介质。

8. 发明授权

US06540672B1 Medical system and a method of controlling the system for use by a patient for medical self treatment 有权
标题翻译：医疗系统和一种控制系统供病人用于医疗自我治疗的方法
公开(公告)号：US06540672B1
公开(公告)日：2003-04-01
申请号：US09450193
申请日：1999-11-29
申请人： Jan Henning Simonsen , Jens Ulrik Poulsen , Kent Halfdan Rokkjaer , Lars Hofmann Christensen , Søren Aasmul , Steffen Iav
发明人： Jan Henning Simonsen , Jens Ulrik Poulsen , Kent Halfdan Rokkjaer , Lars Hofmann Christensen , Søren Aasmul , Steffen Iav
IPC分类号： A61B500
CPC分类号： G06F19/3468 , A61B5/0022 , A61B5/14532 , A61B5/150022 , A61B5/150267 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/15113 , A61B5/157 , A61B5/7264 , A61B2560/0406 , A61B2560/0443 , A61B2562/0219 , A61J1/03 , A61J7/0409 , A61J7/0454 , A61M5/178 , A61M5/31545 , A61M15/0065 , A61M15/0066 , A61M15/008 , A61M2005/3126 , A61M2205/05 , A61M2205/18 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3418 , G06F19/3475 , G06F19/3481 , G16H10/60 , G16H50/20 , Y10S128/903
摘要： This invention relates to an system for self treatment. The system consists of several portable modules where one of the modules is designated as a master module. The master module controls, supervises and monitors all the mutual information and data exchange between itself and the rest of the modules. The modules can e.g. consist of a BGM, a doser, an inhaler, a tablet dispenser and a storage container. The modules may be able to generate and store data which is transmitted to the master module if it is within range and active. If the master module is not within range, the data is kept locally in the module until the master module is available or a new master module is designated. The master module or another specific module can send the data to an external unit like a computer or database for further processing. A physician or an expert care-team can access the data in the database and give guidance to the patient on the basis of these processed data. This processing could also be done automatically by utilization of an expert system.
摘要翻译：本发明涉及一种用于自我治疗的系统。该系统由几个便携式模块组成，其中一个模块被指定为主模块。主模块控制，监督和监视其本身与其余模块之间的所有互信息和数据交换。模块可以例如由BGM，加药器，吸入器，片剂分配器和储存容器组成。如果模块在范围和活动范围内，则模块可能能够生成和存储传输到主模块的数据。如果主模块不在范围内，则将数据本地保存在模块中，直到主模块可用或指定了新的主模块。主模块或另一个特定模块可以将数据发送到外部单元，如计算机或数据库进行进一步处理。医生或专家护理团队可以访问数据库中的数据，并根据这些处理的数据对患者进行指导。这种处理也可以通过利用专家系统自动完成。

9. 发明授权

US5928201A Dose setting device 失效
公开(公告)号：US5928201A
公开(公告)日：1999-07-27
申请号：US878955
申请日：1997-06-19
申请人： Jens Ulrik Poulsen , Henrik Ljunggreen , Lars Hofmann Christensen
发明人： Jens Ulrik Poulsen , Henrik Ljunggreen , Lars Hofmann Christensen
IPC分类号： A61M5/172 , A61M5/145 , A61M5/20 , A61M5/00
CPC分类号： A61M5/20 , A61M2005/31588 , A61M2205/581 , A61M5/14546 , A61M5/14566 , A61M5/31525 , A61M5/31546 , Y10S128/01
摘要： The present invention relates to a drug delivery device wherein a dose to be apportioned from a cartridge is set by changing the relative position of co-operating dose setting elements (3, 5) and is injected by pressing a button (5) until this button abuts a stop (6). By operation of count up (7) or count down (8) buttons the dose is set and read into an electronic circuit (9) comprising a microprocessor and the dose setting movement of the dose setting elements relative to each other is performed by a motor (11) controlled by the circuit in accordance with the read in dose. The set dose is shown on a display (10). The motor (11) is further controlled to perform certain movements of the piston rod (3) so as retraction of this rod when a cartridge (1) is going to be changed an advancing of the piston rod to abutment with the piston (2) after the cartridge has been changed and further to advance this piston to expel air from the cartridge.

10. 发明授权

US06562011B1 Medication delivery device 失效
标题翻译：药物输送装置
公开(公告)号：US06562011B1
公开(公告)日：2003-05-13
申请号：US09348536
申请日：1999-07-07
申请人： Thomas Buch-Rasmussen , Benny Munk , Jens Ulrik Poulsen , Henrik Ljungreen , Peter Møller Jensen , Jens Møller Jensen
发明人： Thomas Buch-Rasmussen , Benny Munk , Jens Ulrik Poulsen , Henrik Ljungreen , Peter Møller Jensen , Jens Møller Jensen
IPC分类号： A61M500
CPC分类号： A61M5/24 , A61M5/31525 , A61M5/31535 , A61M5/31566 , A61M5/31578 , A61M2005/2407 , A61M2005/2488 , A61M2005/2492
摘要： The present invention relates to a medication delivery device comprising a cartridge assembly, a dosing assembly and optionally a needle assembly. The cartridge assembly comprises a cartridge having a stopper adapted to receive a plunger means. Furthermore, the cartridge assembly has one end sealed with a pierceable sealing, said end comprising coupling means for engaging a needle assembly, and another end comprising coupling means for engaging the dosing assembly. At least one of the coupling means of the cartridge assembly is unitarily moulded with the cartridge. The dosing assembly comprises a plunger means and has coupling means for engaging the cartridge assembly. The cartridge assembly and the dosing assembly are coupled together for delivering selected doses of medication. The cartridge is preferably moulded from a plastic material, such as a transparent material, and may be housed in a cartridge housing for protection of the cartridge. The coupling means may be selected from threaded locks, snap locks, hinged locks, or bajonet locks. The medication delivery device is especially suitable for delivering insulin, growth hormone or other medicines.
摘要翻译：本发明涉及药物输送装置，其包括药筒组件，剂量组合件和任选的针组件。盒组件包括具有适于容纳柱塞装置的止动件的盒。此外，盒组件具有用可刺破密封件密封的一端，所述端部包括用于接合针组件的联接装置，以及包括用于接合给药组件的联接装置的另一端。盒组件的联接装置中的至少一个与盒一体地模制。配料组件包括柱塞装置并具有用于接合盒组件的联接装置。药筒组件和剂量组合件联接在一起以递送选定剂量的药物。盒优选地由诸如透明材料的塑料材料成型，并且可以容纳在盒壳体中以保护盒。联接装置可以选自螺纹锁，卡扣锁，铰链锁或双面胶锁。药物输送装置特别适用于输送胰岛素，生长激素或其他药物。

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